Pharmacokinetics and Safety of Single-Dose Amphotericin B Colloidal Dispersion in Healthy Chinese Subjects and Population Pharmacokinetic/Pharmacodynamic Analysis to Inform Clinical Efficacy in Invasive Infections Caused by Candida albicans - Huang, Zhi-Wei; Yu, Ji-Cheng; Wang, Jing-Jing; Chen, Yuan-Cheng; Wu, Ju-Fang; Chen, Yi-Jian; Cao, Guo-Ying; Yang, Hai-Jing; He, Jin-Jie; Dai, Jing-Yi; Zhang, Ji-Yin; Zhang, Wei; et al. (Clinical therapeutics, 2021)
Keywords: Amphotericin B; Amphotericin B - adverse effects; amphotericin B colloidal dispersion; Anti-Bacterial Agents; Antifungal agents; Candida albicans; China; Creatinine; Dosage; Drug dosages; Epidemiological Models; Fungal infections; Humans; Internal Medicine; Intravenous administration; Laboratories; Lipids; Male; Microbial Sensitivity Tests; Monte Carlo Method; Monte Carlo simulation; Pharmacodynamics; pharmacokinetic/pharmacodynamic analysis; Pharmacokinetics; Population; population pharmacokinetics; Software; Treatment Outcome; China; United States--US; pharmacokinetics; amphotericin B colloidal dispersion; pharmacokinetic/pharmacodynamic analysis; population pharmacokinetics