Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex - Ebrahimi-Fakhari, Darius; Saffari, Afshin; Wahlster, Lara; Di Nardo, Alessia; Turner, Daria; Lewis, Tommy L.; Conrad, Christopher; Rothberg, Jonathan M.; Lipton, Jonathan O.; Kölker, Stefan; Hoffmann, Georg F.; Han, Min-Joon; et al. (Cell reports (Cambridge), 2016)
Keywords: Animals; autism; Autophagy; axonal transport; Axons - metabolism; carbamazepine; Cell Respiration; Humans; lysosome; Lysosomes - metabolism; Membrane Potential, Mitochondrial; Mice; mitochondria; Mitochondrial Degradation; Mitochondrial Dynamics; Models, Biological; mTOR; mTORC1; Mutation - genetics; Neurons - metabolism; Neurons - pathology; Pluripotent Stem Cells - metabolism; Presynaptic Terminals - metabolism; rapamycin; synapse; TOR Serine-Threonine Kinases - metabolism; Tuberous Sclerosis - metabolism; Tuberous Sclerosis - pathology; Tumor Suppressor Proteins - metabolism; autophagy; mitochondria; mTOR; axonal transport; synapse; mTORC1; lysosome; autism; rapamycin; carbamazepine