A new boronic acid based fluorescent reporter for catechol

Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter,...

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Published inBioorganic & medicinal chemistry letters Vol. 22; no. 23; pp. 7179 - 7182
Main Authors Wu, Zhongyu, Li, Minyong, Fang, Hao, Wang, Binghe
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier Ltd 01.12.2012
Elsevier
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Online AccessGet full text
ISSN0960-894X
1464-3405
1464-3405
DOI10.1016/j.bmcl.2012.09.060

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Abstract Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter, 2-(4-boronophenyl)quinoline-4-carboxylic acid, which exhibits significant fluorescent property changes upon binding catechol containing molecules in an aqueous solution.
AbstractList Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter, 2-(4-boronophenyl)quinoline-4-carboxylic acid, which exhibits significant fluorescent property changes upon binding catechol containing molecules in an aqueous solution.
Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter, 2-(4-boronophenyl)quinoline-4-carboxylic acid, which exhibits significant fluorescent property changes upon binding catechol containing molecules in an aqueous solution.Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter, 2-(4-boronophenyl)quinoline-4-carboxylic acid, which exhibits significant fluorescent property changes upon binding catechol containing molecules in an aqueous solution.
Author Li, Minyong
Wang, Binghe
Fang, Hao
Wu, Zhongyu
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Issue 23
Keywords Chemosensor
Boronic acid
Catechol detection
BWFFCJJLMPLDBV-UHFFFAOYSA-N
KXZJHVJKXJLBKO-UHFFFAOYSA-N
Fluorescent reporter
Boron Organic compounds
Pyrocatechol
Chemical sensor
Fluorescent compound
Detection
Language English
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Snippet Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the...
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SubjectTerms aqueous solutions
bioactive properties
Biological and medical sciences
Boronic acid
Boronic Acids - chemistry
Catechol
Catechol detection
Catechols - chemistry
Chemosensor
Electron Transport
fluorescence
Fluorescent Dyes - chemistry
Fluorescent reporter
Kinetics
Medical sciences
natural products
Pharmacology. Drug treatments
Spectrometry, Fluorescence
Title A new boronic acid based fluorescent reporter for catechol
URI https://dx.doi.org/10.1016/j.bmcl.2012.09.060
https://www.ncbi.nlm.nih.gov/pubmed/23079526
https://www.proquest.com/docview/1139616181
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