Impact of a Formulation Containing Chaga Extract, Coenzyme Q10, and Alpha-Lipoic Acid on Mitochondrial Dysfunction and Oxidative Stress: NMR Metabolomic Insights into Cellular Energy - D’Elia, Maria; Marino, Carmen; Celano, Rita; Napolitano, Enza; Colarusso, Chiara; Sorrentino, Rosalinda; D’Ursi, Anna Maria; Rastrelli, Luca (Antioxidants, 2025)
Keywords: 1H-NMR metabolomics; Amino acids; Antioxidants; Biological activity; Cell viability; Cholecystokinin; Chromatography; Chronic illnesses; Chronic pain; Coenzyme Q10; Enzymes; Fibromyalgia; Glycolysis; Ingredients; Inonotus obliquus; Lipoic acid; Membrane potential; Metabolic pathways; Metabolism; Metabolites; Metabolomics; Microbiota; Mitochondria; Neuroblastoma; Neuroblasts; NMR; Nuclear magnetic resonance; Oxidative phosphorylation; Oxidative stress; Phosphorylation; Proline; Quality control; Reactive oxygen species; Respiration; SH-SY5Y cells; Systems stability; Tyrosine; UHPLC-HRMS/MS; Variance analysis; Italy; United States--US; UHPLC-HRMS/MS; Inonotus obliquus; coenzyme Q10; neurotransmission; 1H-NMR metabolomics; fibromyalgia; SH-SY5Y cells; cellular metabolism; mitochondrial dysfunction; lipoic acid