Protein and lipid mass concentration measurement in tissues by stimulated Raman scattering microscopy - Oh, Seungeun; Lee, ChangHee; Yang, Wenlong; Li, Ang; Mukherjee, Avik; Basan, Markus; Ran, Chongzhao; Yin, Wei; Tabin, Clifford J.; Fu, Dan; Xie, X. Sunney; Kirschner, Marc W. (Proceedings of the National Academy of Sciences - PNAS, 2022)
Keywords: Alzheimer's disease; Animal tissues; Biological Sciences; Cell cycle; Cerebellum; Chemical composition; Heterogeneity; Homeostasis; Lipid Metabolism; Lipids; Microscopy; Microscopy - methods; Neurodegenerative diseases; Nonlinear Optical Microscopy; Physiology; Proteins; Purkinje cells; Raman spectra; Senescence; Spatial discrimination; Spatial resolution; Spectrum Analysis, Raman - methods; Stiffness; Substrates; Water masses; quantitative microscopy; stimulated Raman scattering; single cell mass quantification; cell size; lipid imaging