Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease - Ding, Qiang; Gaska, Jenna M.; Douam, Florian; Wei, Lei; Kim, David; Balev, Metodi; Heller, Brigitte; Ploss, Alexander (Proceedings of the National Academy of Sciences - PNAS, 2018)
Keywords: Animals; Antiviral drugs; Apes; Biodiversity; Biological Sciences; Chlorocebus aethiops; Cleavage; Cyclic GMP; Dengue fever; Disease control; Disruption; Encephalitis; Fever; Fibroblasts; HEK293 Cells; Host range; Humans; Immunity, Innate; Interferon; Membrane Proteins - genetics; Membrane Proteins - immunology; Mice; Monkeys; Peptide Hydrolases - genetics; Peptide Hydrolases - immunology; Permissivity; Phenotypes; PNAS Plus; Primates; Protease; Proteases; Proteinase; Proteolysis; Ribonucleic acid; RNA; RNA viruses; Rodents; Signal transduction; Signal Transduction - genetics; Signal Transduction - immunology; Signaling; Species Specificity; Stimulators; Tropism; Vector-borne diseases; Vero Cells; Viral diseases; Viral Nonstructural Proteins - genetics; Viral Nonstructural Proteins - immunology; Viruses; West Nile virus; Zika virus; Zika Virus - genetics; Zika Virus - immunology; viral evasion; Zika virus; antiviral immunity; species tropism; flavivirus