Transgenic Tomato Plants Overexpressing Tyramine N -Hydroxycinnamoyltransferase Exhibit Elevated Hydroxycinnamic Acid Amide Levels and Enhanced Resistance to Pseudomonas syringae
Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl...
Saved in:
| Published in | Molecular plant-microbe interactions Vol. 27; no. 10; pp. 1159 - 1169 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
The American Phytopathological Society
01.10.2014
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0894-0282 1943-7706 1943-7706 |
| DOI | 10.1094/MPMI-04-14-0104-R |
Cover
| Abstract | Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl transferase (THT) is the key enzyme in HCAA synthesis and is induced in response to pathogen infection, wounding, or elicitor treatments, preceding HCAA accumulation. We have engineered transgenic tomato plants overexpressing tomato THT. These plants displayed an enhanced THT gene expression in leaves as compared with wild type (WT) plants. Consequently, leaves of THT-overexpressing plants showed a higher constitutive accumulation of the amide coumaroyltyramine (CT). Similar results were found in flowers and fruits. Moreover, feruloyltyramine (FT) also accumulated in these tissues, being present at higher levels in transgenic plants. Accumulation of CT, FT and octopamine, and noradrenaline HCAA in response to Pseudomonas syringae pv. tomato infection was higher in transgenic plants than in the WT plants. Transgenic plants showed an enhanced resistance to the bacterial infection. In addition, this HCAA accumulation was accompanied by an increase in salicylic acid levels and pathogenesis-related gene induction. Taken together, these results suggest that HCAA may play an important role in the defense of tomato plants against P. syringae infection. |
|---|---|
| AbstractList | Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl transferase (THT) is the key enzyme in HCAA synthesis and is induced in response to pathogen infection, wounding, or elicitor treatments, preceding HCAA accumulation. We have engineered transgenic tomato plants overexpressing tomato THT. These plants displayed an enhanced THT gene expression in leaves as compared with wild type (WT) plants. Consequently, leaves of THT-overexpressing plants showed a higher constitutive accumulation of the amide coumaroyltyramine (CT). Similar results were found in flowers and fruits. Moreover, feruloyltyramine (FT) also accumulated in these tissues, being present at higher levels in transgenic plants. Accumulation of CT, FT and octopamine, and noradrenaline HCAA in response to Pseudomonas syringae pv. tomato infection was higher in transgenic plants than in the WT plants. Transgenic plants showed an enhanced resistance to the bacterial infection. In addition, this HCAA accumulation was accompanied by an increase in salicylic acid levels and pathogenesis-related gene induction. Taken together, these results suggest that HCAA may play an important role in the defense of tomato plants against P. syringae infection.Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl transferase (THT) is the key enzyme in HCAA synthesis and is induced in response to pathogen infection, wounding, or elicitor treatments, preceding HCAA accumulation. We have engineered transgenic tomato plants overexpressing tomato THT. These plants displayed an enhanced THT gene expression in leaves as compared with wild type (WT) plants. Consequently, leaves of THT-overexpressing plants showed a higher constitutive accumulation of the amide coumaroyltyramine (CT). Similar results were found in flowers and fruits. Moreover, feruloyltyramine (FT) also accumulated in these tissues, being present at higher levels in transgenic plants. Accumulation of CT, FT and octopamine, and noradrenaline HCAA in response to Pseudomonas syringae pv. tomato infection was higher in transgenic plants than in the WT plants. Transgenic plants showed an enhanced resistance to the bacterial infection. In addition, this HCAA accumulation was accompanied by an increase in salicylic acid levels and pathogenesis-related gene induction. Taken together, these results suggest that HCAA may play an important role in the defense of tomato plants against P. syringae infection. Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl transferase (THT) is the key enzyme in HCAA synthesis and is induced in response to pathogen infection, wounding, or elicitor treatments, preceding HCAA accumulation. We have engineered transgenic tomato plants overexpressing tomato THT. These plants displayed an enhanced THT gene expression in leaves as compared with wild type (WT) plants. Consequently, leaves of THT-overexpressing plants showed a higher constitutive accumulation of the amide coumaroyltyramine (CT). Similar results were found in flowers and fruits. Moreover, feruloyltyramine (FT) also accumulated in these tissues, being present at higher levels in transgenic plants. Accumulation of CT, FT and octopamine, and noradrenaline HCAA in response to Pseudomonas syringae pv. tomato infection was higher in transgenic plants than in the WT plants. Transgenic plants showed an enhanced resistance to the bacterial infection. In addition, this HCAA accumulation was accompanied by an increase in salicylic acid levels and pathogenesis-related gene induction. Taken together, these results suggest that HCAA may play an important role in the defense of tomato plants against P. syringae infection. |
| Author | Lisón, Purificación Zacarés, Laura López-Gresa, María Pilar Rodrigo, Ismael Conejero, Vicente Bellés, José María Campos, Laura |
| Author_xml | – sequence: 1 givenname: Laura surname: Campos fullname: Campos, Laura – sequence: 2 givenname: Purificación surname: Lisón fullname: Lisón, Purificación – sequence: 3 givenname: María Pilar surname: López-Gresa fullname: López-Gresa, María Pilar – sequence: 4 givenname: Ismael surname: Rodrigo fullname: Rodrigo, Ismael – sequence: 5 givenname: Laura surname: Zacarés fullname: Zacarés, Laura – sequence: 6 givenname: Vicente surname: Conejero fullname: Conejero, Vicente – sequence: 7 givenname: José María surname: Bellés fullname: Bellés, José María |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25014592$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFks1uEzEUhUeoiKaFB2CDvGQzYI_t-VlGVaCRUlpFYW3dGd9JXc3YwZ6EzGvxhHhIqfiRYGXL_s7xkc-9SM6ss5gkrxl9x2gl3t_c3SxTKlImUsriun6WzFgleFoUND9LZrSs4k1WZufJRQgPlLIql_JFcp5JyoSsslnybePBhi1a05CN62Fw5K4DOwRye0CPx53HEIzdks3ooTcWySeSXo_au-PYGGuhd2M3TB4teghIFsd7U5uBLDo8wICa_AbHV-aN0WTeG41khQfsAgGrycLeg20ivsZgwjDtyZQl4F673lkIJIw-BgF8mTxvoQv46nG9TD5_WGyurtPV7cfl1XyVNpJWQ8pRgihLiQ1gXQJqzniORSGqNqMVLzHHCnkZ_03UXFNR8lZrxiVOtGA5v0yWJ1_t4EHtvOnBj8qBUT8OnN8q8INpOlSgJaBALJkUIiuauoFK1Bmv2zqvZYbRKzt57e0Oxq_QdU-GjKqpTNXveqOoUEyoqUzlo-jtSbTz7ssew6B6ExrsYj_o9kFlNDbKpeTFf1Emc0orSYsJffOI7use9VOOnzMRAXYCGu9C8Nj-FXWau1-jrqOm-EPTmAEG42ycDdP9Q_kdkgvgYw |
| CitedBy_id | crossref_primary_10_1038_s41598_022_13876_w crossref_primary_10_1016_j_plantsci_2017_01_014 crossref_primary_10_1111_nph_17982 crossref_primary_10_1093_jxb_eraa511 crossref_primary_10_1093_plphys_kiaa043 crossref_primary_10_1371_journal_pone_0155851 crossref_primary_10_3389_fpls_2019_01390 crossref_primary_10_1021_acs_jafc_6b05136 crossref_primary_10_1002_cbdv_202100436 crossref_primary_10_1111_jipb_12480 crossref_primary_10_3389_fpls_2024_1376405 crossref_primary_10_1071_FP17299 crossref_primary_10_1093_hr_uhad248 crossref_primary_10_1093_plphys_kiab453 crossref_primary_10_1094_PHYTOFR_09_22_0101_R crossref_primary_10_1111_tpj_14420 crossref_primary_10_1038_s41598_023_47648_x crossref_primary_10_1186_s12934_015_0353_y crossref_primary_10_1111_ppl_14169 crossref_primary_10_3389_fpls_2022_922119 crossref_primary_10_3390_metabo13090997 crossref_primary_10_1007_s10295_017_1975_3 crossref_primary_10_1093_jxb_eraa582 crossref_primary_10_1016_j_scib_2021_03_015 crossref_primary_10_1093_jxb_erv423 crossref_primary_10_3390_ijms24054764 crossref_primary_10_1016_j_tplants_2020_09_011 crossref_primary_10_1111_mpp_12854 crossref_primary_10_3389_fpls_2020_617520 crossref_primary_10_1371_journal_pone_0166938 crossref_primary_10_3389_fpls_2021_675208 crossref_primary_10_1038_hortres_2016_62 crossref_primary_10_3389_fpls_2018_01522 crossref_primary_10_1016_j_phytochem_2018_02_003 crossref_primary_10_1080_07060661_2016_1199597 crossref_primary_10_1093_hr_uhad154 crossref_primary_10_1186_s12864_019_6381_y crossref_primary_10_1186_s12870_022_03939_5 crossref_primary_10_1111_jipb_13204 crossref_primary_10_1007_s11306_024_02174_3 crossref_primary_10_1007_s12374_015_0104_y crossref_primary_10_1007_s44154_023_00140_y crossref_primary_10_1016_j_jfda_2017_06_002 crossref_primary_10_1093_jxb_erad040 crossref_primary_10_1016_j_jgg_2022_02_008 crossref_primary_10_1007_s10265_022_01409_5 crossref_primary_10_1007_s11101_015_9417_1 crossref_primary_10_3390_ijms20163945 crossref_primary_10_1007_s00299_020_02629_6 crossref_primary_10_1021_jacsau_4c00577 crossref_primary_10_3389_fpls_2017_01595 crossref_primary_10_1038_s41598_023_48269_0 crossref_primary_10_3390_plants12142695 crossref_primary_10_3390_cimb46010007 crossref_primary_10_2525_ecb_54_17 crossref_primary_10_1038_s41598_020_62752_y crossref_primary_10_1111_jipb_12810 crossref_primary_10_1007_s13765_017_0315_7 crossref_primary_10_1186_s42483_022_00119_z crossref_primary_10_1016_j_biopha_2020_110762 crossref_primary_10_1186_s12870_019_2063_9 crossref_primary_10_1111_pce_12640 crossref_primary_10_32615_bp_2023_034 crossref_primary_10_3389_fpls_2023_1218914 crossref_primary_10_1094_MPMI_09_14_0292_FI crossref_primary_10_1016_j_scib_2021_06_014 crossref_primary_10_1111_tpj_13960 crossref_primary_10_1021_acschembio_5b00893 |
| Cites_doi | 10.1186/1471-2105-12-404 10.1016/0031-9422(96)00173-2 10.1094/MPMI.1999.12.3.227 10.1146/annurev.pp.40.060189.002023 10.1007/BF00015818 10.1094/MPMI-20-11-1439 10.1271/bbb.70033 10.1094/MPMI.2001.14.6.785 10.1248/cpb.45.1910 10.1016/S0031-9422(00)88735-X 10.1007/s004250050295 10.1126/science.266.5188.1247 10.1007/s00216-010-4129-2 10.1016/j.plaphy.2014.01.016 10.1093/ajcn/42.4.639 10.1016/j.scienta.2009.12.036 10.1016/B978-012214674-9/50011-4 10.1111/j.1365-313X.2005.02372.x 10.1139/b02-065 10.1016/j.scienta.2006.01.037 10.1080/11263509909381549 10.1089/jir.1998.18.423 10.1007/s00425-005-0109-8 10.1023/B:BILE.0000035483.85790.f7 10.1007/BF00203609 10.1105/tpc.108.063511 10.1016/S0031-9422(97)00620-1 10.1007/s00425-009-0960-0 10.1074/jbc.274.7.4273 10.1007/s004250050604 10.1016/j.plantsci.2008.02.008 10.1016/0031-9422(95)00866-7 10.1080/07352689991309397 10.1016/S0031-9422(00)84681-6 10.1016/j.scienta.2008.12.015 10.1111/j.1399-3054.1990.tb09057.x 10.1104/pp.104.2.315 10.1016/j.phytochem.2010.08.003 10.1016/0031-9422(84)83018-6 10.1016/j.plantsci.2006.07.012 10.1094/MPMI.1997.10.5.624 10.1007/s00425-005-1484-x 10.1074/jbc.M305084200 10.1104/pp.108.117754 10.1007/978-1-4615-7598-6_24 10.1007/BF00393865 10.1104/pp.106.086587 10.1146/annurev.phyto.44.070505.143425 10.1111/j.1432-1033.1997.01127.x 10.1016/S0176-1617(11)80392-5 10.1007/BF00196893 10.1016/j.envexpbot.2011.06.003 10.1006/bbrc.2002.6752 10.1248/bpb.27.1976 10.1089/jmf.2007.514 10.1080/10575630008041225 10.1007/s00122-002-0928-y |
| ContentType | Journal Article |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 ADTOC UNPAY DOA |
| DOI | 10.1094/MPMI-04-14-0104-R |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic Unpaywall for CDI: Periodical Content Unpaywall DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE - Academic CrossRef MEDLINE AGRICOLA |
| Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals - DOAJ (NTUSG) url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Agriculture Biology |
| EISSN | 1943-7706 |
| EndPage | 1169 |
| ExternalDocumentID | oai_doaj_org_article_ad5ae4ee8154427cbca94b23bfb6b52e 10.1094/mpmi-04-14-0104-r 25014592 10_1094_MPMI_04_14_0104_R |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- 123 29M 2WC 53G 7X2 7X7 88E 8AO 8CJ 8FE 8FH 8FI 8FJ 8FW 8R4 8R5 AAHBH AAYJJ AAYXX ABDNZ ABRJW ABUWG ACGFO ACPRK ACYGS ADBBV AENEX AEUYN AFKRA AFRAH ALMA_UNASSIGNED_HOLDINGS ATCPS BAWUL BBNVY BENPR BES BHPHI BPHCQ BVXVI C1A CCPQU CITATION CS3 D1J DIK DU5 E3Z EBS EJD F5P FRP FYUFA GROUPED_DOAJ HCIFZ HMCUK HYO LK8 M0K M1P M7P MVM OK1 P2P PHGZM PHGZT PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PUEGO Q2X RPS S0X TR2 UKHRP ~KM ALIPV CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 ADTOC UNPAY |
| ID | FETCH-LOGICAL-c509t-3e5a4885ecaeb8aed3136e7749f20938e6e9e381044b3d0483fdd135eeb8a4163 |
| IEDL.DBID | UNPAY |
| ISSN | 0894-0282 1943-7706 |
| IngestDate | Fri Oct 03 12:49:11 EDT 2025 Sun Oct 26 04:02:32 EDT 2025 Thu Sep 04 18:16:33 EDT 2025 Fri Sep 05 08:05:16 EDT 2025 Mon Jul 21 05:28:45 EDT 2025 Wed Oct 01 00:55:14 EDT 2025 Thu Apr 24 22:51:12 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 10 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c509t-3e5a4885ecaeb8aed3136e7749f20938e6e9e381044b3d0483fdd135eeb8a4163 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://proxy.k.utb.cz/login?url=https://apsjournals.apsnet.org/doi/pdf/10.1094/MPMI-04-14-0104-R |
| PMID | 25014592 |
| PQID | 1560095077 |
| PQPubID | 23479 |
| PageCount | 11 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_ad5ae4ee8154427cbca94b23bfb6b52e unpaywall_primary_10_1094_mpmi_04_14_0104_r proquest_miscellaneous_2000135537 proquest_miscellaneous_1560095077 pubmed_primary_25014592 crossref_primary_10_1094_MPMI_04_14_0104_R crossref_citationtrail_10_1094_MPMI_04_14_0104_R |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2014-10-00 2014-Oct 20141001 2014-10-01 |
| PublicationDateYYYYMMDD | 2014-10-01 |
| PublicationDate_xml | – month: 10 year: 2014 text: 2014-10-00 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Molecular plant-microbe interactions |
| PublicationTitleAlternate | Mol Plant Microbe Interact |
| PublicationYear | 2014 |
| Publisher | The American Phytopathological Society |
| Publisher_xml | – name: The American Phytopathological Society |
| References | p_49 p_45 p_46 p_47 p_48 p_42 Naranjo M. A. (p_41) 2003; 217 p_43 p_44 p_40 p_38 p_2 p_1 p_4 p_34 p_3 p_35 p_6 p_36 p_5 p_37 p_8 p_7 p_9 p_30 p_31 p_32 p_33 p_27 p_28 p_29 p_23 p_24 p_25 p_26 p_20 p_21 Muroi A. (p_39) 2012; 2 p_22 p_60 p_61 p_16 p_17 p_18 p_19 p_12 p_56 p_13 p_57 p_14 p_58 p_15 p_59 p_52 p_53 p_10 p_54 p_11 p_55 p_50 p_51 |
| References_xml | – ident: p_33 doi: 10.1186/1471-2105-12-404 – ident: p_37 doi: 10.1016/0031-9422(96)00173-2 – ident: p_2 doi: 10.1094/MPMI.1999.12.3.227 – ident: p_18 doi: 10.1146/annurev.pp.40.060189.002023 – ident: p_9 doi: 10.1007/BF00015818 – volume: 2 start-page: 689 year: 2012 ident: p_39 publication-title: Rep. – ident: p_60 doi: 10.1094/MPMI-20-11-1439 – ident: p_54 doi: 10.1271/bbb.70033 – ident: p_47 doi: 10.1094/MPMI.2001.14.6.785 – ident: p_61 doi: 10.1248/cpb.45.1910 – ident: p_34 doi: 10.1016/S0031-9422(00)88735-X – ident: p_51 doi: 10.1007/s004250050295 – ident: p_10 doi: 10.1126/science.266.5188.1247 – ident: p_19 doi: 10.1007/s00216-010-4129-2 – ident: p_6 doi: 10.1016/j.plaphy.2014.01.016 – ident: p_15 doi: 10.1093/ajcn/42.4.639 – ident: p_22 doi: 10.1016/j.scienta.2009.12.036 – ident: p_53 doi: 10.1016/B978-012214674-9/50011-4 – ident: p_8 doi: 10.1111/j.1365-313X.2005.02372.x – ident: p_13 doi: 10.1139/b02-065 – ident: p_23 doi: 10.1016/j.scienta.2006.01.037 – ident: p_14 doi: 10.1080/11263509909381549 – ident: p_24 doi: 10.1089/jir.1998.18.423 – ident: p_3 doi: 10.1007/s00425-005-0109-8 – ident: p_27 doi: 10.1023/B:BILE.0000035483.85790.f7 – ident: p_16 doi: 10.1007/BF00203609 – ident: p_31 doi: 10.1105/tpc.108.063511 – ident: p_49 doi: 10.1016/S0031-9422(97)00620-1 – ident: p_38 doi: 10.1007/s00425-009-0960-0 – ident: p_52 doi: 10.1074/jbc.274.7.4273 – ident: p_59 doi: 10.1007/s004250050604 – ident: p_4 doi: 10.1016/j.plantsci.2008.02.008 – ident: p_25 doi: 10.1016/0031-9422(95)00866-7 – ident: p_11 doi: 10.1080/07352689991309397 – ident: p_36 – ident: p_43 doi: 10.1016/S0031-9422(00)84681-6 – ident: p_21 doi: 10.1016/j.scienta.2008.12.015 – ident: p_57 doi: 10.1111/j.1399-3054.1990.tb09057.x – ident: p_29 doi: 10.1104/pp.104.2.315 – ident: p_1 doi: 10.1016/j.phytochem.2010.08.003 – ident: p_45 doi: 10.1016/0031-9422(84)83018-6 – ident: p_26 doi: 10.1016/j.plantsci.2006.07.012 – ident: p_55 doi: 10.1094/MPMI.1997.10.5.624 – ident: p_17 doi: 10.1007/s00425-005-1484-x – ident: p_58 doi: 10.1074/jbc.M305084200 – ident: p_5 doi: 10.1104/pp.108.117754 – ident: p_35 doi: 10.1007/978-1-4615-7598-6_24 – ident: p_44 doi: 10.1007/BF00393865 – volume: 217 start-page: 417 year: 2003 ident: p_41 publication-title: Panta. – ident: p_28 doi: 10.1104/pp.106.086587 – ident: p_56 doi: 10.1146/annurev.phyto.44.070505.143425 – ident: p_42 doi: 10.1111/j.1432-1033.1997.01127.x – ident: p_7 – ident: p_46 doi: 10.1016/S0176-1617(11)80392-5 – ident: p_20 doi: 10.1007/BF00196893 – ident: p_30 doi: 10.1016/j.envexpbot.2011.06.003 – ident: p_48 doi: 10.1006/bbrc.2002.6752 – ident: p_50 doi: 10.1248/bpb.27.1976 – ident: p_32 doi: 10.1089/jmf.2007.514 – ident: p_40 doi: 10.1080/10575630008041225 – ident: p_12 doi: 10.1007/s00122-002-0928-y |
| SSID | ssj0019655 |
| Score | 2.4134414 |
| Snippet | Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant... |
| SourceID | doaj unpaywall proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 1159 |
| SubjectTerms | Acyltransferases - genetics Acyltransferases - metabolism amides Amides - metabolism antifungal properties antioxidants bacterial infections coumaric acids Coumaric Acids - metabolism Disease Resistance elicitors flowers Flowers - enzymology Flowers - genetics Flowers - immunology Flowers - microbiology Fruit - enzymology Fruit - genetics Fruit - immunology Fruit - microbiology fruits Gene Expression Gene Expression Regulation, Enzymologic Gene Expression Regulation, Plant gene induction gene overexpression Genes, Reporter hydroxycinnamoyltransferase leaves Lycopersicon esculentum - enzymology Lycopersicon esculentum - genetics Lycopersicon esculentum - immunology Lycopersicon esculentum - microbiology norepinephrine octopamine pathogens plant development Plant Diseases - immunology Plant Diseases - microbiology Plant Leaves - enzymology Plant Leaves - genetics Plant Leaves - immunology Plant Leaves - microbiology Plant Proteins - genetics Plant Proteins - metabolism Plants, Genetically Modified Pseudomonas syringae - physiology Pseudomonas syringae pv. tomato salicylic acid Salicylic Acid - metabolism secondary metabolites tissues tomatoes transgenic plants tyramine Tyramine - analogs & derivatives Tyramine - metabolism |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Zj9MwELbQSgj2AcFylUtG4gkUbRI7SfNYUFcF0QVVXWnfIh-TJVKOKkmB_Cz-ITNJWnXF9cJTrnFix-PMZ8_kG8ZeoYVREETCUaHSjlSucWK02s7UelLFvvUiQ-uQy_NwcSE_XAaXB6m-KCZsoAceXtypsngzCTAl2hg_MtqoWGpf6FSHOvCBvr7uNN5Npkb_QRz2-U7xgnRoVrHzZ8bydPl5-Z7cAR5FX-B2dc0i9cT9v0Obx-zWttyo7pvK8wMLdHaX3RmhI58NVb7HbkB5wo5nV_VInwEn7OaQWrK7z370Rgi1IzN8XSEsrTjlJ2ob_gmVF74P8a_lFV93tSoQavJzZ9FZCmoxWVmqourytge1UKOh43NKpJ21fJ7DV4Snll8TxofMTGb5rMgs8I8UiNRwVVo-L7_0IQZ8BQ0hVdznVJUGtrbCEaAa3nS0tKjgAbs4m6_fLZwxPYNjEGW0joBA4fAPwCjQUwVWeCIEhJNx6ruxmEIIMRCBmJRaWKKuT631RAAkTTjwITsqqxIeM65SnSqRpl6AxbXxtNGpENKVeOi64E2Yu-uixIzc5ZRCI08GH7pMqFcTV-JMJqFeTVYT9npfZDMQd_xN-C31-16QOLf7E6iJyaiJyb80ccJe7rQmwTFKjhdVQrVtEvpbHaGsG0V_lvF7NB4EAmUeDSq3r47fO39jf8Le7HXwl0YVmyI7bFT95H806im7jRBRDuGLz9hRW2_hOcKwVr_oR9xPPyQyyw priority: 102 providerName: Directory of Open Access Journals |
| Title | Transgenic Tomato Plants Overexpressing Tyramine N -Hydroxycinnamoyltransferase Exhibit Elevated Hydroxycinnamic Acid Amide Levels and Enhanced Resistance to Pseudomonas syringae |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/25014592 https://www.proquest.com/docview/1560095077 https://www.proquest.com/docview/2000135537 https://apsjournals.apsnet.org/doi/pdf/10.1094/MPMI-04-14-0104-R https://doaj.org/article/ad5ae4ee8154427cbca94b23bfb6b52e |
| UnpaywallVersion | publishedVersion |
| Volume | 27 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVBFR databaseName: Free Medical Journals - Free Access to All customDbUrl: eissn: 1943-7706 dateEnd: 20241105 omitProxy: true ssIdentifier: ssj0019655 issn: 0894-0282 databaseCode: DIK dateStart: 19880101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3dj5NAEN9oL8bcgx-npzXarIlPGk5ggZbHanrpqa2Xpk3OJ7Ifw0lsoQGq4n_lf-gM0KbnV2J84iMD7MLMzm93ht8w9gw9jAS_LywZSGV50tZWiF7bGhjHk6FrnL6mdcjJNBgvvDcX_sXeX_xyXbQvsTjBfZye1-F8su-1iVv-I-_l5HxyRmv6DqVQ4HZ2nR0EPqLxDjtYTM-HH2rwSKy3bl0vCqfqAoGkHWwDm3iP1XqV7N8jv-Kaagb_38HOQ3Zzk65l9UUul3uu6PQ2k9tONBkon042pTrR337id_yfXt5ht1qcyoeNYt1l1yA9YofDy7zl6oAjdqOpY1ndY99rj4eqmGg-zxADZ5yKIZUFf4-WAl-bZNv0ks-rXK4Q1_KpNa4MtV8naSpXWbUsawQNOXpVPqKq3UnJR0v4jFjY8CvC-JChTgwfrhID_B1lPRVcpoaP0o91PgOfQUGwGPc5NaWAjcnQ3GTBi4rWMSXcZ4vT0fz12GprQVgaIU1pCfAljjU-aAlqIMEIRwSA2DWMXTsUAwggBGIr8zwlDPHkx8Y4wgeSJtB5zDpplsJDxmWsYini2PHxcqUdpVUshGd7eGjb4HSZvVWDSLdE6VSvYxk1AXsvou8S2R5OmyL6LtGsy57vLlk3LCF_E35FurUTJILv-gSqQNSOF5E0aEMewIDYkty-VlqGnnKFilWgfBe67OlWMyMcECjKI1PINkVEv8Yjbrb7_T_LuDX0932BMg8atd41x60jzaHbZS92ev5Lp8h29juVP_on6cesU-YbeIJ4rlQ9nMmcve3VqyG91nx_ANliTYg |
| linkProvider | Unpaywall |
| linkToUnpaywall | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1br5NAEN5oT4w5D16Otxo1a-KThgrsQstjNT2pxtaTpk2OT2Qvw5HYQgNUrf_Kf-gM0KbHW2J84pIBdmFm59ud4RvGnqGHURD0haNCpR2pXONE6LWdgfWkinzr9Q2tQ06m4Xgh354H5wd_8at12b7Esof7OD2vw_lk32ubtPxH8uXkbPKG1vQ9SqHA7ewqOwoDROMddrSYng0_1OCRWG_9ul4UTtUFAkk33AU28R6r9So9vEdxyTXVDP6_g53H7PomW6vtF7VcHrii05tM7TrRZKB86m0q3TPffuJ3_J9e3mI3WpzKh41i3WZXIDthx8OLouXqgBN2raljub3DvtceD1UxNXyeIwbOORVDqkr-Hi0FvjbJttkFn28LtUJcy6fOeGup_SbNMrXKt8uqRtBQoFflI6ranVZ8tITPiIUtvySMDxma1PLhKrXA31HWU8lVZvko-1jnM_AZlASLcZ9TU0rY2BzNTZW83NI6poK7bHE6mr8eO20tCMcgpKkcAYHCsSYAo0APFFjhiRAQu0aJ70ZiACFEQGxlUmphiSc_sdYTAZA0gc57rJPlGTxgXCU6USJJvAAv18bTRidCSFfioeuC12XuTg1i0xKlU72OZdwE7GVM3yV2JU6bYvou8azLnu8vWTcsIX8TfkW6tRckgu_6BKpA3I4XsbJoQxJgQGxJft9ooyKpfaETHerAhy57utPMGAcEivKoDPJNGdOv8Yib3X7_zzJ-Df2DQKDM_Uat983x60hz5HfZi72e_9Ipsp3DThUP_0n6EetUxQYeI56r9JPWZH8ASCNLmg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Transgenic+Tomato+Plants+Overexpressing+Tyramine+N+-Hydroxycinnamoyltransferase+Exhibit+Elevated+Hydroxycinnamic+Acid+Amide+Levels+and+Enhanced+Resistance+to+Pseudomonas+syringae&rft.jtitle=Molecular+plant-microbe+interactions&rft.au=Campos%2C+Laura&rft.au=Lis%C3%B3n%2C+Purificaci%C3%B3n&rft.au=L%C3%B3pez-Gresa%2C+Mar%C3%ADa+Pilar&rft.au=Rodrigo%2C+Ismael&rft.date=2014-10-01&rft.issn=0894-0282&rft.eissn=1943-7706&rft.volume=27&rft.issue=10&rft.spage=1159&rft.epage=1169&rft_id=info:doi/10.1094%2FMPMI-04-14-0104-R&rft.externalDBID=n%2Fa&rft.externalDocID=10_1094_MPMI_04_14_0104_R |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0894-0282&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0894-0282&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0894-0282&client=summon |