A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug - Wallace, John L.; Nagy, Peter; Feener, Troy D.; Allain, Thibault; Ditrói, Tamás; Vaughan, David J.; Muscara, Marcelo N.; Nucci, Gilberto; Buret, Andre G. (British journal of pharmacology, 2020)
Keywords: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Cyclooxygenase Inhibitors; Double-Blind Method; Dyspepsia; Esophagus; Gastroesophageal reflux; Humans; Hydrogen Sulfide; Inflammation; Naproxen; Naproxen - adverse effects; Nausea; Pharmaceutical Preparations; Plasma levels; Research Paper; Themed Section: Research Paper; Toxicity; Ulcers