Evidence that oncostatin M synergizes with IL-4 signaling to induce TSLP expression in chronic rhinosinusitis with nasal polyps - Wang, Bao-Feng; Cao, Ping-Ping; Norton, James E.; Poposki, Julie A.; Klingler, Aiko I.; Suh, Lydia A.; Carter, Roderick; Huang, Julia H.; Bai, Junqin; Stevens, Whitney W.; Tan, Bruce K.; Peters, Anju T.; et al. (Journal of allergy and clinical immunology, 2023)
Keywords: Chronic Disease; chronic rhinosinusitis; Cytokines - metabolism; Humans; IL-4Rα; Inflammation - metabolism; Interleukin-4 - metabolism; nasal epithelial cells; Nasal Mucosa - metabolism; nasal polyps; Nasal Polyps - metabolism; Oncostatin M - metabolism; OSM; OSMRβ; Proprotein Convertases - metabolism; Rhinitis - metabolism; Sinusitis - metabolism; Subtilisins - metabolism; Thymic Stromal Lymphopoietin; TSLP; type 2–dominant inflammation; IL-13Rα1; NP; IL-13Rα2; TSLP; CRS; DMSO; OSM; OSMRβ; CRSwNP; LIFR; NHBEC; BMEM; NEC; CRSsNP; EREG; PCSK3; type 2–dominant inflammation; chronic rhinosinusitis; nasal polyps; STAT6; nasal epithelial cells; ALI; IL-4Rα; UT