Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis - Huby, Anne-Cécile; Antonova, Galina; Groenendyk, Jake; Gomez-Sanchez, Celso E.; Bollag, Wendy B.; Filosa, Jessica A.; de Chantemèle, Eric J. Belin (Circulation (New York, N.Y.), 2015)
Keywords: Adipocytes - secretion; Adrenal Cortex - cytology; Adrenal Cortex - secretion; Aldosterone - secretion; Animals; Cell Line, Tumor; Cells, Cultured; Endothelium, Vascular - secretion; Female; Fibrosis - pathology; Heart Diseases - metabolism; Heart Diseases - pathology; Humans; Leptin - physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Rats; Rats, Inbred WKY; Rats, Zucker; endothelium; CYP11B2; aldosterone; adrenal glands; leptin; heart; obesity