Brain Responses to Visceral Stimuli Reflect Visceral Sensitivity Thresholds in Patients With Irritable Bowel Syndrome - Larsson, Mats B.O.; Tillisch, Kirsten; Craig, A.D.; Engström, Maria; Labus, Jennifer; Naliboff, Bruce; Lundberg, Peter; Ström, Magnus; Mayer, Emeran A.; Walter, Susanna A. (Gastroenterology (New York, N.Y. 1943), 2012)
Keywords: Abdominal Pain - diagnosis; Abdominal Pain - physiopathology; Abdominal Pain - psychology; Adult; Afferent Pathways - physiopathology; Anticipation; Anxiety - physiopathology; Anxiety - psychology; Barostat; Brain - physiopathology; Brain Mapping - methods; Case-Control Studies; Depression - physiopathology; Depression - psychology; Female; Functional MRI; Gastroenterology and Hepatology; Humans; Irritable Bowel Syndrome - diagnosis; Irritable Bowel Syndrome - physiopathology; Irritable Bowel Syndrome - psychology; Linear Models; Magnetic Resonance Imaging; Mechanotransduction, Cellular; Middle Aged; Pain Measurement; Pain Threshold; Pressure; Rectum - innervation; Sensory Receptor Cells; Severity of Illness Index; Surveys and Questionnaires; Sweden; Visceral Sensitivity; Young Adult; Sweden; HIPP; GI; pACC; DLPFC; MRI; Anticipation; HAD; ROI; INS; fMRI; Barostat; Visceral Sensitivity; Functional MRI; BOLD; HC; IBS; blood oxygen level–dependent; magnetic resonance imaging; insula; dorsolateral prefrontal cortex; pregenual anterior cingulate cortex; Hospital Anxiety and Depression scale; hippocampus; irritable bowel syndrome; gastrointestinal; region of interest; healthy control; functional magnetic resonance imaging