Anaphylaxis knowledge gaps and future research priorities: A consensus report
Despite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and prioritizing these gaps would allow limited scientific resources to be directed more effectively. We sought to systematically describe and appra...
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| Published in | Journal of allergy and clinical immunology Vol. 149; no. 3; pp. 999 - 1009 |
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| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.03.2022
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0091-6749 1097-6825 1097-6825 |
| DOI | 10.1016/j.jaci.2021.07.035 |
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| Abstract | Despite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and prioritizing these gaps would allow limited scientific resources to be directed more effectively.
We sought to systematically describe and appraise anaphylaxis knowledge gaps and future research priorities based on their potential impact and feasibility.
We convened a 25-member multidisciplinary panel of anaphylaxis experts. Panelists formulated knowledge gaps/research priority statements in an anonymous electronic survey. Four anaphylaxis themed writing groups were formed to refine statements: (1) Population Science, (2) Basic and Translational Sciences, (3) Emergency Department Care/Acute Management, and (4) Long-Term Management Strategies and Prevention. Revised statements were incorporated into an anonymous electronic survey, and panelists were asked to rate the impact and feasibility of addressing statements on a continuous 0 to 100 scale.
The panel generated 98 statements across the 4 anaphylaxis themes: Population Science (29), Basic and Translational Sciences (27), Emergency Department Care/Acute Management (24), and Long-Term Management Strategies and Prevention (18). Median scores for impact and feasibility ranged from 50.0 to 95.0 and from 40.0 to 90.0, respectively. Key statements based on median rating for impact/feasibility included the need to refine anaphylaxis diagnostic criteria, identify reliable diagnostic, predictive, and prognostic anaphylaxis bioassays, develop clinical prediction models to standardize postanaphylaxis observation periods and hospitalization criteria, and determine immunotherapy best practices.
We identified and systematically appraised anaphylaxis knowledge gaps and future research priorities. This study reinforces the need to harmonize scientific pursuits to optimize the outcomes of patients with and at risk of anaphylaxis. |
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| AbstractList | Despite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and prioritizing these gaps would allow limited scientific resources to be directed more effectively.
We sought to systematically describe and appraise anaphylaxis knowledge gaps and future research priorities based on their potential impact and feasibility.
We convened a 25-member multidisciplinary panel of anaphylaxis experts. Panelists formulated knowledge gaps/research priority statements in an anonymous electronic survey. Four anaphylaxis themed writing groups were formed to refine statements: (1) Population Science, (2) Basic and Translational Sciences, (3) Emergency Department Care/Acute Management, and (4) Long-Term Management Strategies and Prevention. Revised statements were incorporated into an anonymous electronic survey, and panelists were asked to rate the impact and feasibility of addressing statements on a continuous 0 to 100 scale.
The panel generated 98 statements across the 4 anaphylaxis themes: Population Science (29), Basic and Translational Sciences (27), Emergency Department Care/Acute Management (24), and Long-Term Management Strategies and Prevention (18). Median scores for impact and feasibility ranged from 50.0 to 95.0 and from 40.0 to 90.0, respectively. Key statements based on median rating for impact/feasibility included the need to refine anaphylaxis diagnostic criteria, identify reliable diagnostic, predictive, and prognostic anaphylaxis bioassays, develop clinical prediction models to standardize postanaphylaxis observation periods and hospitalization criteria, and determine immunotherapy best practices.
We identified and systematically appraised anaphylaxis knowledge gaps and future research priorities. This study reinforces the need to harmonize scientific pursuits to optimize the outcomes of patients with and at risk of anaphylaxis. We established and appraised anaphylaxis knowledge gaps and future research priorities; multinational, multidisciplinary collaborations are needed to resolve these gaps with the ultimate goal of optimizing patient outcomes and lessening the societal burden of anaphylaxis. Despite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and prioritizing these gaps would allow limited scientific resources to be directed more effectively.BACKGROUNDDespite a better understanding of the epidemiology, pathogenesis, and management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and prioritizing these gaps would allow limited scientific resources to be directed more effectively.We sought to systematically describe and appraise anaphylaxis knowledge gaps and future research priorities based on their potential impact and feasibility.OBJECTIVEWe sought to systematically describe and appraise anaphylaxis knowledge gaps and future research priorities based on their potential impact and feasibility.We convened a 25-member multidisciplinary panel of anaphylaxis experts. Panelists formulated knowledge gaps/research priority statements in an anonymous electronic survey. Four anaphylaxis themed writing groups were formed to refine statements: (1) Population Science, (2) Basic and Translational Sciences, (3) Emergency Department Care/Acute Management, and (4) Long-Term Management Strategies and Prevention. Revised statements were incorporated into an anonymous electronic survey, and panelists were asked to rate the impact and feasibility of addressing statements on a continuous 0 to 100 scale.METHODSWe convened a 25-member multidisciplinary panel of anaphylaxis experts. Panelists formulated knowledge gaps/research priority statements in an anonymous electronic survey. Four anaphylaxis themed writing groups were formed to refine statements: (1) Population Science, (2) Basic and Translational Sciences, (3) Emergency Department Care/Acute Management, and (4) Long-Term Management Strategies and Prevention. Revised statements were incorporated into an anonymous electronic survey, and panelists were asked to rate the impact and feasibility of addressing statements on a continuous 0 to 100 scale.The panel generated 98 statements across the 4 anaphylaxis themes: Population Science (29), Basic and Translational Sciences (27), Emergency Department Care/Acute Management (24), and Long-Term Management Strategies and Prevention (18). Median scores for impact and feasibility ranged from 50.0 to 95.0 and from 40.0 to 90.0, respectively. Key statements based on median rating for impact/feasibility included the need to refine anaphylaxis diagnostic criteria, identify reliable diagnostic, predictive, and prognostic anaphylaxis bioassays, develop clinical prediction models to standardize postanaphylaxis observation periods and hospitalization criteria, and determine immunotherapy best practices.RESULTSThe panel generated 98 statements across the 4 anaphylaxis themes: Population Science (29), Basic and Translational Sciences (27), Emergency Department Care/Acute Management (24), and Long-Term Management Strategies and Prevention (18). Median scores for impact and feasibility ranged from 50.0 to 95.0 and from 40.0 to 90.0, respectively. Key statements based on median rating for impact/feasibility included the need to refine anaphylaxis diagnostic criteria, identify reliable diagnostic, predictive, and prognostic anaphylaxis bioassays, develop clinical prediction models to standardize postanaphylaxis observation periods and hospitalization criteria, and determine immunotherapy best practices.We identified and systematically appraised anaphylaxis knowledge gaps and future research priorities. This study reinforces the need to harmonize scientific pursuits to optimize the outcomes of patients with and at risk of anaphylaxis.CONCLUSIONSWe identified and systematically appraised anaphylaxis knowledge gaps and future research priorities. This study reinforces the need to harmonize scientific pursuits to optimize the outcomes of patients with and at risk of anaphylaxis. |
| Author | Schneider, Lynda C. Wang, Julie Capucilli, Peter S. Rudders, Susan A. Campbell, Dianne E. Dribin, Timothy E. Lee, Juhee Campbell, Ronna L. Sampson, Hugh A. Witry, John K. Schnadower, David Brousseau, David C. Worm, Margitta Turner, Paul J. Zhang, Yin Castells, Mariana Risma, Kimberly A. Mistry, Rakesh D. Shaker, Marcus Vyles, David Golden, David B.K. Michelson, Kenneth A. Camargo, Carlos A. Pistiner, Michael Spergel, Jonathan M. Neuman, Mark I. Sobolewski, Brad Assa’ad, Amal H. |
| AuthorAffiliation | 9 Division of Allergy and Immunology, Children’s Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 2 Division of Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY 7 Section of Pediatric Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 20 Division of Emergency Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 5 Dartmouth Geisel School of Medicine, and Dartmouth-Hitchcock Medical Center, Hanover and Lebanon, NH 6 Division of Immunology, Boston Children’s Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA 4 Division of Emergency Medicine, Boston Children’s Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA 17 Department of Allergy and Immunology, Children’s Hospital at Westmead, Sydney, Australia 1 Division of Emergency Medicine, Cincinnati Children’s Hospital Medical Center, and the Department of Ped |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34390722$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.anai.2019.01.014 10.1016/S0140-6736(19)30420-9 10.1016/j.jaip.2016.06.003 10.2196/jmir.3.2.e20 10.1016/j.jaip.2019.07.034 10.1111/cea.13287 10.1001/jamanetworkopen.2019.13951 10.1016/j.jaip.2019.07.018 10.1016/j.iac.2011.10.002 10.1097/ACI.0000000000000305 10.1016/j.jaci.2016.02.015 10.1111/all.13132 10.1016/j.jbi.2008.08.010 10.1111/acem.12922 10.1016/j.jaip.2019.09.037 10.1007/s11882-018-0831-5 10.1016/j.waojou.2019.100066 10.1038/s41598-019-56961-3 10.1016/j.jaip.2020.11.005 10.1016/j.waojou.2020.100472 10.1016/j.anai.2020.05.029 10.1056/NEJMoa1200435 10.1016/j.jaip.2020.05.007 10.1016/j.jaip.2019.01.006 10.1038/s41591-018-0324-z 10.1016/j.jaip.2020.08.041 10.1007/s11577-017-0454-1 10.1016/j.jaci.2020.01.017 10.1016/j.jaci.2013.08.016 10.1016/j.jaci.2009.07.055 10.1016/j.jaip.2021.03.005 10.1016/j.jaci.2020.06.033 10.1016/j.jaip.2019.09.028 10.1056/NEJMoa022952 10.1111/all.14468 10.1016/j.jaci.2011.09.030 10.1016/j.jaci.2020.06.008 10.1016/j.jaci.2021.02.012 10.1016/j.jaip.2021.02.046 10.1016/S2213-2600(15)00087-9 10.1016/j.jaci.2014.10.021 10.1111/all.12437 10.1172/JCI138448 10.1056/NEJMoa070030 10.1016/j.jaci.2021.01.003 10.18865/ed.30.S1.129 10.1016/j.jaip.2018.10.052 10.1126/science.aaw6433 10.1016/j.jaip.2019.11.027 10.1016/j.jaci.2021.04.017 10.1016/j.jaci.2017.02.007 10.1016/j.jaci.2017.06.012 10.1016/j.jaci.2020.08.015 10.1016/j.jaci.2020.06.035 10.1016/j.jaci.2021.04.031 10.1177/1558689818778469 10.1016/j.jaip.2015.12.019 10.1016/j.jaip.2014.03.014 10.1016/j.jaci.2011.01.031 10.1016/j.jaci.2005.12.1303 10.1016/j.jaip.2017.06.031 10.1056/NEJMra1807761 10.1016/j.jaci.2013.06.015 10.1016/j.resuscitation.2021.04.010 10.1016/j.anai.2020.09.003 10.1016/j.anai.2019.12.023 10.3389/fimmu.2015.00620 10.1016/j.jaci.2018.02.018 10.3389/fimmu.2018.01584 |
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| References | DeJonckheere, Lindquist-Grantz, Toraman, Haddad, Vaughn (bib60) 2018; 13 Ruiz-Garcia, Bartra, Alvarez, Lakhani, Patel, Tang (bib44) 2021; 147 Pascal, Perez-Gordo, Caballero, Escribese, Lopez Longo, Luengo (bib14) 2018; 9 Castells (bib13) 2017; 140 Sloane, Govindarajulu, Harrow-Mortelliti, Barry, Hsu, Hong (bib4) 2016; 4 Tanno, Chalmers, Jacob, Kostanjsek, Bierrenbach, Martin (bib63) 2020; 75 Krystel-Whittemore, Dileepan, Wood (bib42) 2016; 6 Shaker, Wallace, Golden, Oppenheimer, Greenhawt (bib47) 2019; 2 Griffith (bib68) 2020; 30 Dribin, Sampson, Camargo, Brousseau, Spergel, Neuman (bib28) 2020; 146 Castells, Khan, Phillips (bib52) 2019; 381 Sampson, Muñoz-Furlong, Campbell, Adkinson, Bock, Branum (bib1) 2006; 117 Harris, Taylor, Thielke, Payne, Gonzalez, Conde (bib30) 2009; 42 Bilaver, Chadha, Doshi, O’Dweyer, Gupta (bib8) 2019; 122 Arthur (bib22) 2015; 3 Greenhawt, Shaker (bib57) 2020; 125 Schoonenboom, Johnson (bib61) 2017; 69 Stafford, Patel, Turner (bib31) 2021; 148 Shaker, Mosnaim, Oppenheimer, Stukus, Abrams, Greenhawt (bib59) 2020; 8 Hemmings, Kwok, McKendry, Santos (bib66) 2018; 18 Chong, Ruiz-Garcia, Patel, Boyle, Turner (bib34) 2020; 124 Cardona, Ansotegui, Ebisawa, El-Gamal, Fernandez Rivas, Fineman (bib18) 2020; 13 Turner, Jerschow, Umasunthar, Lin, Campbell, Boyle (bib11) 2017; 5 Brown, Asai, Cordell, Campbell, Zhao, Liao (bib27) 2011; 127 Burks, Jones, Wood, Fleischer, Sicherer, Lindblad (bib19) 2012; 367 Dribin, Schnadower, Spergel, Campbell, Shaker, Neuman (bib29) 2021; 148 Brown, Stone, Fatovich, Burrows, Holdgate, Celenza (bib16) 2013; 132 Hogan (bib32) 2021; 148 Gowthaman, Chen, Zhang, Flynn, Lu, Song (bib35) 2019; 365 Dribin, Michelson, Monuteaux, Schnadower, Neuman (bib46) 2020; 8 Robinson, Arroyo, Faridi, Rudders, Camargo (bib48) 2021; 126 Francuzik, Ruëff, Bauer, Bilò, Cardona, Christoff (bib33) 2021; 147 Vadas, Gold, Perelman, Liss, Lack, Blyth (bib15) 2008; 358 Cianferoni, Muraro (bib7) 2012; 32 Turner, Ruiz-Garcia, Durham, Boyle (bib43) 2021; 9 Finkelman, Khodoun, Strait (bib25) 2016; 137 Dodd, Hughes, Sargant, Whyte, Soar, Turner (bib51) 2021; 163 Eysenbach (bib69) 2001; 3 Turner, Gowland, Sharma, Ierodiakonou, Harper, Garcez (bib23) 2015; 135 Valent, Akin, Bonadonna, Hartmann, Brockow, Niedoszytko (bib40) 2019; 7 Huang, Marsland, Bunyavanich, O’Mahony, Leung, Muraro (bib37) 2017; 139 Feehley, Plunkett, Bao, Choi Hong, Culleen, Belda-Ferre (bib36) 2019; 25 Turner, Campbell (bib41) 2016; 16 Aun, Blanca, Garro, Ribeiro, Kalil, Motta (bib6) 2014; 2 Stone, Cotterell, Isbister, Holdgate, Brown (bib26) 2009; 124 Goldberg, Nachshon, Levy, Elizur, Katz (bib56) 2020; 8 Cianferoni (bib24) 2021; 147 Muraro, Lemanske, Castells, Torres, Khan, Simon (bib62) 2017; 72 Greenhawt, Gupta, Meadows, Pistiner, Spergel, Camargo (bib50) 2019; 7 Pistiner, Mendez-Reyes, Eftekhari, Carver, Lieberman, Wang (bib49) 2021; 9 Chu, Wood, French, Fiocchi, Jordana, Waserman (bib54) 2019; 393 Golden, Kagey-Sobotka, Norman, Hamilton, Lichtenstein (bib20) 2004; 351 Michelson, Dribin, Vyles, Neuman (bib9) 2020; 8 Turner, Campbell, Motosue, Campbell (bib3) 2020; 8 Lyons, Chovanec, O’Connell, Liu, Šelb, Zanotti (bib38) 2021; 147 Muraro, Roberts, Worm, Bilò, Brockow, Fernández Rivas (bib53) 2014; 69 Campbell, Hagan, Manivannan, Decker, Kanthala, Bellolio (bib64) 2012; 129 Dispenza, Krier-Burris, Chhiba, Undem, Robida, Bochner (bib67) 2020; 130 Luskin, White, Lyons (bib39) 2021; 9 Isabwe, Garcia Neuer, de las Vecillas Sanchez, Lynch, Marquis, Castells (bib5) 2018; 142 Pouessel, Turner, Worm, Cardona, Deschildre, Beaudouin (bib12) 2018; 48 Turner, Worm, Ansotegui, El-Gamal, Rivas, Fineman (bib17) 2019; 12 Wood, Camargo, Lieberman, Sampson, Schwartz, Zitt (bib10) 2014; 133 Shaker, Wallace, Golden, Oppenheimer, Bernstein, Campbell (bib2) 2020; 145 Grzeskowiak, Tao, Knight, Cohen-Woods, Chataway (bib21) 2020; 10 Michelson, Monuteaux, Neuman (bib45) 2016; 23 Wasserman, Factor, Windom, Abrams, Begin, Chan (bib55) 2021; 9 Shaker, Briggs, Dbouk, Dutille, Oppenheimer, Greenhawt (bib58) 2020; 8 Brauer, Motosue, Li, Hagan, Bellolio, Lee (bib65) 2016; 4 Griffith (10.1016/j.jaci.2021.07.035_bib68) 2020; 30 Michelson (10.1016/j.jaci.2021.07.035_bib9) 2020; 8 Dribin (10.1016/j.jaci.2021.07.035_bib29) 2021; 148 Feehley (10.1016/j.jaci.2021.07.035_bib36) 2019; 25 Turner (10.1016/j.jaci.2021.07.035_bib23) 2015; 135 Greenhawt (10.1016/j.jaci.2021.07.035_bib50) 2019; 7 Ruiz-Garcia (10.1016/j.jaci.2021.07.035_bib44) 2021; 147 Dodd (10.1016/j.jaci.2021.07.035_bib51) 2021; 163 Muraro (10.1016/j.jaci.2021.07.035_bib62) 2017; 72 Aun (10.1016/j.jaci.2021.07.035_bib6) 2014; 2 Chong (10.1016/j.jaci.2021.07.035_bib34) 2020; 124 Cianferoni (10.1016/j.jaci.2021.07.035_bib7) 2012; 32 Stafford (10.1016/j.jaci.2021.07.035_bib31) 2021; 148 Cianferoni (10.1016/j.jaci.2021.07.035_bib24) 2021; 147 Goldberg (10.1016/j.jaci.2021.07.035_bib56) 2020; 8 Turner (10.1016/j.jaci.2021.07.035_bib41) 2016; 16 Sampson (10.1016/j.jaci.2021.07.035_bib1) 2006; 117 Michelson (10.1016/j.jaci.2021.07.035_bib45) 2016; 23 Robinson (10.1016/j.jaci.2021.07.035_bib48) 2021; 126 Hemmings (10.1016/j.jaci.2021.07.035_bib66) 2018; 18 Huang (10.1016/j.jaci.2021.07.035_bib37) 2017; 139 Greenhawt (10.1016/j.jaci.2021.07.035_bib57) 2020; 125 Valent (10.1016/j.jaci.2021.07.035_bib40) 2019; 7 Sloane (10.1016/j.jaci.2021.07.035_bib4) 2016; 4 Cardona (10.1016/j.jaci.2021.07.035_bib18) 2020; 13 Chu (10.1016/j.jaci.2021.07.035_bib54) 2019; 393 Campbell (10.1016/j.jaci.2021.07.035_bib64) 2012; 129 Vadas (10.1016/j.jaci.2021.07.035_bib15) 2008; 358 Shaker (10.1016/j.jaci.2021.07.035_bib47) 2019; 2 Turner (10.1016/j.jaci.2021.07.035_bib17) 2019; 12 Wasserman (10.1016/j.jaci.2021.07.035_bib55) 2021; 9 Eysenbach (10.1016/j.jaci.2021.07.035_bib69) 2001; 3 Stone (10.1016/j.jaci.2021.07.035_bib26) 2009; 124 Golden (10.1016/j.jaci.2021.07.035_bib20) 2004; 351 Finkelman (10.1016/j.jaci.2021.07.035_bib25) 2016; 137 Lyons (10.1016/j.jaci.2021.07.035_bib38) 2021; 147 Luskin (10.1016/j.jaci.2021.07.035_bib39) 2021; 9 Schoonenboom (10.1016/j.jaci.2021.07.035_bib61) 2017; 69 Turner (10.1016/j.jaci.2021.07.035_bib11) 2017; 5 Castells (10.1016/j.jaci.2021.07.035_bib52) 2019; 381 Castells (10.1016/j.jaci.2021.07.035_bib13) 2017; 140 Brown (10.1016/j.jaci.2021.07.035_bib27) 2011; 127 DeJonckheere (10.1016/j.jaci.2021.07.035_bib60) 2018; 13 Bilaver (10.1016/j.jaci.2021.07.035_bib8) 2019; 122 Wood (10.1016/j.jaci.2021.07.035_bib10) 2014; 133 Pistiner (10.1016/j.jaci.2021.07.035_bib49) 2021; 9 Brauer (10.1016/j.jaci.2021.07.035_bib65) 2016; 4 Hogan (10.1016/j.jaci.2021.07.035_bib32) 2021; 148 Shaker (10.1016/j.jaci.2021.07.035_bib2) 2020; 145 Turner (10.1016/j.jaci.2021.07.035_bib3) 2020; 8 Dribin (10.1016/j.jaci.2021.07.035_bib28) 2020; 146 Pascal (10.1016/j.jaci.2021.07.035_bib14) 2018; 9 Francuzik (10.1016/j.jaci.2021.07.035_bib33) 2021; 147 Shaker (10.1016/j.jaci.2021.07.035_bib59) 2020; 8 Grzeskowiak (10.1016/j.jaci.2021.07.035_bib21) 2020; 10 Krystel-Whittemore (10.1016/j.jaci.2021.07.035_bib42) 2016; 6 Pouessel (10.1016/j.jaci.2021.07.035_bib12) 2018; 48 Gowthaman (10.1016/j.jaci.2021.07.035_bib35) 2019; 365 Harris (10.1016/j.jaci.2021.07.035_bib30) 2009; 42 Dribin (10.1016/j.jaci.2021.07.035_bib46) 2020; 8 Tanno (10.1016/j.jaci.2021.07.035_bib63) 2020; 75 Dispenza (10.1016/j.jaci.2021.07.035_bib67) 2020; 130 Isabwe (10.1016/j.jaci.2021.07.035_bib5) 2018; 142 Burks (10.1016/j.jaci.2021.07.035_bib19) 2012; 367 Turner (10.1016/j.jaci.2021.07.035_bib43) 2021; 9 Arthur (10.1016/j.jaci.2021.07.035_bib22) 2015; 3 Muraro (10.1016/j.jaci.2021.07.035_bib53) 2014; 69 Shaker (10.1016/j.jaci.2021.07.035_bib58) 2020; 8 Brown (10.1016/j.jaci.2021.07.035_bib16) 2013; 132 |
| References_xml | – volume: 13 year: 2020 ident: bib18 article-title: World Allergy Organization Anaphylaxis Guidance 2020 publication-title: World Allergy Organ J – volume: 2 year: 2019 ident: bib47 article-title: Simulation of health and economic benefits of extended observation of resolved anaphylaxis publication-title: JAMA Netw Open – volume: 7 start-page: 1148 year: 2019 end-page: 1156.e5 ident: bib50 article-title: Guiding principles for the recognition, diagnosis, and management of infants with anaphylaxis: an expert panel consensus publication-title: J Allergy Clin Immunol Pract – volume: 145 start-page: 1082 year: 2020 end-page: 1123 ident: bib2 article-title: Anaphylaxis--a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis publication-title: J Allergy Clin Immunol – volume: 147 start-page: 653 year: 2021 end-page: 662.e9 ident: bib33 article-title: Phenotype and risk factors of venom-induced anaphylaxis: a case-control study of the European Anaphylaxis Registry publication-title: J Allergy Clin Immunol – volume: 117 start-page: 391 year: 2006 end-page: 397 ident: bib1 article-title: Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium publication-title: J Allergy Clin Immunol – volume: 4 start-page: 497 year: 2016 end-page: 504 ident: bib4 article-title: Safety, costs, and efficacy of rapid drug desensitizations to chemotherapy and monoclonal antibodies publication-title: J Allergy Clin Immunol Pract – volume: 6 start-page: 620 year: 2016 ident: bib42 article-title: Mast cell: a multi-functional master cell publication-title: Front Immunol – volume: 135 start-page: 956 year: 2015 end-page: 963.e1 ident: bib23 article-title: Increase in anaphylaxis-related hospitalizations but no increase in fatalities: an analysis of United Kingdom national anaphylaxis data, 1992-2012 publication-title: J Allergy Clin Immunol – volume: 148 start-page: 83 year: 2021 end-page: 85 ident: bib31 article-title: Anaphylaxis – moving beyond severity… publication-title: J Allergy Clin Immunol – volume: 367 start-page: 233 year: 2012 end-page: 243 ident: bib19 article-title: Oral immunotherapy for treatment of egg allergy in children publication-title: N Engl J Med – volume: 72 start-page: 1006 year: 2017 end-page: 1021 ident: bib62 article-title: Precision medicine in allergic disease — food allergy, drug allergy, and anaphylaxis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology publication-title: Allergy – volume: 148 start-page: 86 year: 2021 end-page: 88 ident: bib32 article-title: Commentary: severity grading system for acute allergic reactions. Time for validation and assessment of best practices publication-title: J Allergy Clin Immunol – volume: 25 start-page: 448 year: 2019 end-page: 453 ident: bib36 article-title: Healthy infants harbor intestinal bacteria that protect against food allergy publication-title: Nat Med – volume: 13 start-page: 481 year: 2018 end-page: 502 ident: bib60 article-title: Intersection of mixed methods and community-based participatory research: a methodological review publication-title: J Mix Methods Res – volume: 16 start-page: 441 year: 2016 end-page: 450 ident: bib41 article-title: Epidemiology of severe anaphylaxis: can we use population-based data to understand anaphylaxis? publication-title: Curr Opin Allergy Clin Immunol – volume: 8 start-page: 2310 year: 2020 end-page: 2321.e4 ident: bib59 article-title: Health and economic outcomes of home maintenance allergen immunotherapy in select patients with high health literacy during the COVID-19 pandemic: a cost-effectiveness analysis during exceptional times publication-title: J Allergy Clin Immunol Pract – volume: 142 start-page: 159 year: 2018 end-page: 170.e2 ident: bib5 article-title: Hypersensitivity reactions to therapeutic monoclonal antibodies: phenotypes and endotypes publication-title: J Allergy Clin Immunol – volume: 393 start-page: 2222 year: 2019 end-page: 2232 ident: bib54 article-title: Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety publication-title: Lancet – volume: 133 start-page: 461 year: 2014 end-page: 467 ident: bib10 article-title: Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States publication-title: J Allergy Clin Immunol – volume: 4 start-page: 1220 year: 2016 end-page: 1226 ident: bib65 article-title: Prospective validation of the NIAID/FAAN Criteria for Emergency Department Diagnosis of Anaphylaxis publication-title: J Allergy Clin Immunol Pract – volume: 48 start-page: 1584 year: 2018 end-page: 1593 ident: bib12 article-title: Food-induced fatal anaphylaxis: from epidemiological data to general prevention strategies publication-title: Clin Exp Allergy – volume: 2 start-page: 414 year: 2014 end-page: 420 ident: bib6 article-title: Nonsteroidal anti-inflammatory drugs are major causes of drug-induced anaphylaxis publication-title: J Allergy Clin Immunol Pract – volume: 147 start-page: 633 year: 2021 end-page: 642 ident: bib44 article-title: Cardiovascular changes during peanut-induced allergic reactions in human subjects publication-title: J Allergy Clin Immunol – volume: 140 start-page: 321 year: 2017 end-page: 333 ident: bib13 article-title: Diagnosis and management of anaphylaxis in precision medicine publication-title: J Allergy Clin Immunol – volume: 163 start-page: 86 year: 2021 end-page: 96 ident: bib51 article-title: Evidence update for the treatment of anaphylaxis publication-title: Resuscitation – volume: 8 start-page: 565 year: 2020 end-page: 572 ident: bib58 article-title: Estimation of health and economic benefits of clinic versus home administration of omalizumab and mepolizumab publication-title: J Allergy Clin Immunol Pract – volume: 9 start-page: 527 year: 2021 end-page: 530.e1 ident: bib43 article-title: Limited effect of intramuscular epinephrine on cardiovascular parameters during peanut-induced anaphylaxis: an observational cohort study publication-title: J Allergy Clin Immunol Pract – volume: 32 start-page: 165 year: 2012 end-page: 195 ident: bib7 article-title: Food-induced anaphylaxis publication-title: Immunol Allergy Clin North Am – volume: 10 start-page: 659 year: 2020 ident: bib21 article-title: Adverse events associated with peanut oral immunotherapy in children – a systematic review and meta-analysis publication-title: Sci Rep – volume: 124 start-page: 473 year: 2020 end-page: 478 ident: bib34 article-title: Reaction phenotypes in IgE-mediated food allergy and anaphylaxis publication-title: Ann Allergy Asthma Immunol – volume: 9 start-page: 1826 year: 2021 end-page: 1838.e8 ident: bib55 article-title: An approach to the office-based practice of food oral immunotherapy publication-title: J Allergy Clin Immunol Pract – volume: 8 start-page: 125 year: 2020 end-page: 131 ident: bib56 article-title: Risk factors and treatment outcomes for oral immunotherapy–induced gastrointestinal symptoms and eosinophilic responses (OITIGER) publication-title: J Allergy Clin Immunol Pract – volume: 147 start-page: 1123 year: 2021 end-page: 1131 ident: bib24 article-title: Non--IgE-mediated anaphylaxis publication-title: J Allergy Clin Immunol – volume: 23 start-page: 623 year: 2016 end-page: 627 ident: bib45 article-title: Variation and trends in anaphylaxis care in United States children’s hospitals publication-title: Acad Emerg Med – volume: 69 start-page: 1026 year: 2014 end-page: 1045 ident: bib53 article-title: Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology publication-title: Allergy – volume: 12 year: 2019 ident: bib17 article-title: Time to revisit the definition and clinical criteria for anaphylaxis? publication-title: World Allergy Organ J – volume: 8 start-page: 1169 year: 2020 end-page: 1176 ident: bib3 article-title: Global trends in anaphylaxis epidemiology and clinical implications publication-title: J Allergy Clin Immunol Pract – volume: 129 start-page: 748 year: 2012 end-page: 752 ident: bib64 article-title: Evaluation of National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network criteria for the diagnosis of anaphylaxis in emergency department patients publication-title: J Allergy Clin Immunol – volume: 122 start-page: 373 year: 2019 end-page: 380 ident: bib8 article-title: Economic burden of food allergy—a systematic review publication-title: Ann Allergy Asthma Immunol – volume: 30 start-page: 129 year: 2020 end-page: 134 ident: bib68 article-title: Precision medicine approaches to health disparities research publication-title: Ethn Dis – volume: 125 start-page: 124 year: 2020 end-page: 125 ident: bib57 article-title: Keeping risk in context while rethinking the setting of asthma biologics in patient-centered care publication-title: Ann Allergy Asthma Immunol – volume: 132 start-page: 1141 year: 2013 end-page: 1149.e5 ident: bib16 article-title: Anaphylaxis: clinical patterns, mediator release, and severity publication-title: J Allergy Clin Immunol – volume: 42 start-page: 377 year: 2009 end-page: 381 ident: bib30 article-title: Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support publication-title: J Biomed Inf – volume: 75 start-page: 2206 year: 2020 end-page: 2218 ident: bib63 article-title: Global implementation of the World Health Organization’s International Classification of Diseases (ICD)-11: the allergic and hypersensitivity conditions model publication-title: Allergy – volume: 358 start-page: 28 year: 2008 end-page: 35 ident: bib15 article-title: Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis publication-title: N Engl J Med – volume: 146 start-page: 1089 year: 2020 end-page: 1096 ident: bib28 article-title: Persistent, refractory, and biphasic anaphylaxis: a multidisciplinary Delphi study publication-title: J Allergy Clin Immunol – volume: 381 start-page: 2338 year: 2019 end-page: 2351 ident: bib52 article-title: Penicillin allergy publication-title: N Engl J Med – volume: 351 start-page: 668 year: 2004 end-page: 674 ident: bib20 article-title: Outcomes of allergy to insect stings in children, with and without venom immunotherapy publication-title: N Engl J Med – volume: 9 start-page: 311 year: 2021 end-page: 320.e2 ident: bib49 article-title: Caregiver reported presentation of severe food-induced allergic reactions in infants and toddlers publication-title: J Allergy Clin Immunol Pract – volume: 126 start-page: 168 year: 2021 end-page: 174.e3 ident: bib48 article-title: Trends in US hospitalizations for anaphylaxis among infants and toddlers: 2006 to 2015 publication-title: Ann Allergy Asthma Immunol – volume: 3 start-page: 350 year: 2015 end-page: 351 ident: bib22 article-title: Epinephrine: a short history publication-title: Lancet Respir Med – volume: 148 start-page: 173 year: 2021 end-page: 181 ident: bib29 article-title: Severity grading system for acute allergic reactions: a multidisciplinary Delphi study publication-title: J Allergy Clin Immunol – volume: 139 start-page: 1099 year: 2017 end-page: 1110 ident: bib37 article-title: The microbiome in allergic disease: current understanding and future opportunities--2017 PRACTALL document of the American Academy of Allergy, Asthma and Immunology and the European Academy of Allergy and Clinical Immunology publication-title: J Allergy Clin Immunol – volume: 9 start-page: 1584 year: 2018 ident: bib14 article-title: Microbiome and allergic diseases publication-title: Front Immunol – volume: 137 start-page: 1674 year: 2016 end-page: 1680 ident: bib25 article-title: Human IgE-independent systemic anaphylaxis publication-title: J Allergy Clin Immunol – volume: 5 start-page: 1169 year: 2017 end-page: 1178 ident: bib11 article-title: Fatal anaphylaxis: mortality rate and risk factors publication-title: J Allergy Clin Immunol Pract – volume: 18 start-page: 77 year: 2018 ident: bib66 article-title: Basophil activation test: old and new applications in allergy publication-title: Curr Allergy Asthma Rep – volume: 130 start-page: 4759 year: 2020 end-page: 4770 ident: bib67 article-title: Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis publication-title: J Clin Invest – volume: 3 year: 2001 ident: bib69 article-title: What is e-health? publication-title: J Med Internet Res – volume: 127 start-page: 661 year: 2011 end-page: 667 ident: bib27 article-title: Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy publication-title: J Allergy Clin Immunol – volume: 365 year: 2019 ident: bib35 article-title: Identification of a T follicular helper cell subset that drives anaphylactic IgE publication-title: Science – volume: 124 start-page: 786 year: 2009 end-page: 792.e4 ident: bib26 article-title: Elevated serum cytokines during human anaphylaxis: identification of potential mediators of acute allergic reactions publication-title: J Allergy Clin Immunol – volume: 9 start-page: 2235 year: 2021 end-page: 2242 ident: bib39 article-title: The genetic basis and clinical impact of hereditary alpha-tryptasemia publication-title: J Allergy Clin Immunol Pract – volume: 69 start-page: 107 year: 2017 end-page: 131 ident: bib61 article-title: How to construct a mixed methods research design publication-title: Kolner Z Soz Sozpsychol – volume: 7 start-page: 1125 year: 2019 end-page: 1133.e1 ident: bib40 article-title: Proposed diagnostic algorithm for patients with suspected mast cell activation syndrome publication-title: J Allergy Clin Immunol Pract – volume: 8 start-page: 1400 year: 2020 end-page: 1402.e2 ident: bib46 article-title: Timing and predictors of repeat epinephrine administration among children hospitalized for anaphylaxis publication-title: J Allergy Clin Immunol Pract – volume: 8 start-page: 767 year: 2020 end-page: 768.e2 ident: bib9 article-title: Trends in emergency care for anaphylaxis publication-title: J Allergy Clin Immunol Pract – volume: 147 start-page: 622 year: 2021 end-page: 632 ident: bib38 article-title: Heritable risk for severe anaphylaxis associated with increased α-tryptase–encoding germline copy number at TPSAB1 publication-title: J Allergy Clin Immunol – volume: 122 start-page: 373 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib8 article-title: Economic burden of food allergy—a systematic review publication-title: Ann Allergy Asthma Immunol doi: 10.1016/j.anai.2019.01.014 – volume: 393 start-page: 2222 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib54 article-title: Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety publication-title: Lancet doi: 10.1016/S0140-6736(19)30420-9 – volume: 4 start-page: 1220 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib65 article-title: Prospective validation of the NIAID/FAAN Criteria for Emergency Department Diagnosis of Anaphylaxis publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2016.06.003 – volume: 3 year: 2001 ident: 10.1016/j.jaci.2021.07.035_bib69 article-title: What is e-health? publication-title: J Med Internet Res doi: 10.2196/jmir.3.2.e20 – volume: 8 start-page: 125 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib56 article-title: Risk factors and treatment outcomes for oral immunotherapy–induced gastrointestinal symptoms and eosinophilic responses (OITIGER) publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.07.034 – volume: 48 start-page: 1584 year: 2018 ident: 10.1016/j.jaci.2021.07.035_bib12 article-title: Food-induced fatal anaphylaxis: from epidemiological data to general prevention strategies publication-title: Clin Exp Allergy doi: 10.1111/cea.13287 – volume: 2 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib47 article-title: Simulation of health and economic benefits of extended observation of resolved anaphylaxis publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2019.13951 – volume: 8 start-page: 767 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib9 article-title: Trends in emergency care for anaphylaxis publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.07.018 – volume: 32 start-page: 165 year: 2012 ident: 10.1016/j.jaci.2021.07.035_bib7 article-title: Food-induced anaphylaxis publication-title: Immunol Allergy Clin North Am doi: 10.1016/j.iac.2011.10.002 – volume: 16 start-page: 441 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib41 article-title: Epidemiology of severe anaphylaxis: can we use population-based data to understand anaphylaxis? publication-title: Curr Opin Allergy Clin Immunol doi: 10.1097/ACI.0000000000000305 – volume: 137 start-page: 1674 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib25 article-title: Human IgE-independent systemic anaphylaxis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2016.02.015 – volume: 72 start-page: 1006 year: 2017 ident: 10.1016/j.jaci.2021.07.035_bib62 article-title: Precision medicine in allergic disease — food allergy, drug allergy, and anaphylaxis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology publication-title: Allergy doi: 10.1111/all.13132 – volume: 42 start-page: 377 year: 2009 ident: 10.1016/j.jaci.2021.07.035_bib30 article-title: Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support publication-title: J Biomed Inf doi: 10.1016/j.jbi.2008.08.010 – volume: 23 start-page: 623 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib45 article-title: Variation and trends in anaphylaxis care in United States children’s hospitals publication-title: Acad Emerg Med doi: 10.1111/acem.12922 – volume: 8 start-page: 565 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib58 article-title: Estimation of health and economic benefits of clinic versus home administration of omalizumab and mepolizumab publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.09.037 – volume: 18 start-page: 77 year: 2018 ident: 10.1016/j.jaci.2021.07.035_bib66 article-title: Basophil activation test: old and new applications in allergy publication-title: Curr Allergy Asthma Rep doi: 10.1007/s11882-018-0831-5 – volume: 12 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib17 article-title: Time to revisit the definition and clinical criteria for anaphylaxis? publication-title: World Allergy Organ J doi: 10.1016/j.waojou.2019.100066 – volume: 10 start-page: 659 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib21 article-title: Adverse events associated with peanut oral immunotherapy in children – a systematic review and meta-analysis publication-title: Sci Rep doi: 10.1038/s41598-019-56961-3 – volume: 9 start-page: 311 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib49 article-title: Caregiver reported presentation of severe food-induced allergic reactions in infants and toddlers publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2020.11.005 – volume: 13 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib18 article-title: World Allergy Organization Anaphylaxis Guidance 2020 publication-title: World Allergy Organ J doi: 10.1016/j.waojou.2020.100472 – volume: 125 start-page: 124 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib57 article-title: Keeping risk in context while rethinking the setting of asthma biologics in patient-centered care publication-title: Ann Allergy Asthma Immunol doi: 10.1016/j.anai.2020.05.029 – volume: 367 start-page: 233 year: 2012 ident: 10.1016/j.jaci.2021.07.035_bib19 article-title: Oral immunotherapy for treatment of egg allergy in children publication-title: N Engl J Med doi: 10.1056/NEJMoa1200435 – volume: 8 start-page: 2310 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib59 article-title: Health and economic outcomes of home maintenance allergen immunotherapy in select patients with high health literacy during the COVID-19 pandemic: a cost-effectiveness analysis during exceptional times publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2020.05.007 – volume: 7 start-page: 1125 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib40 article-title: Proposed diagnostic algorithm for patients with suspected mast cell activation syndrome publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.01.006 – volume: 25 start-page: 448 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib36 article-title: Healthy infants harbor intestinal bacteria that protect against food allergy publication-title: Nat Med doi: 10.1038/s41591-018-0324-z – volume: 9 start-page: 527 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib43 article-title: Limited effect of intramuscular epinephrine on cardiovascular parameters during peanut-induced anaphylaxis: an observational cohort study publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2020.08.041 – volume: 69 start-page: 107 year: 2017 ident: 10.1016/j.jaci.2021.07.035_bib61 article-title: How to construct a mixed methods research design publication-title: Kolner Z Soz Sozpsychol doi: 10.1007/s11577-017-0454-1 – volume: 145 start-page: 1082 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib2 article-title: Anaphylaxis--a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2020.01.017 – volume: 133 start-page: 461 year: 2014 ident: 10.1016/j.jaci.2021.07.035_bib10 article-title: Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2013.08.016 – volume: 124 start-page: 786 year: 2009 ident: 10.1016/j.jaci.2021.07.035_bib26 article-title: Elevated serum cytokines during human anaphylaxis: identification of potential mediators of acute allergic reactions publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.07.055 – volume: 9 start-page: 2235 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib39 article-title: The genetic basis and clinical impact of hereditary alpha-tryptasemia publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2021.03.005 – volume: 147 start-page: 633 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib44 article-title: Cardiovascular changes during peanut-induced allergic reactions in human subjects publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2020.06.033 – volume: 8 start-page: 1400 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib46 article-title: Timing and predictors of repeat epinephrine administration among children hospitalized for anaphylaxis publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.09.028 – volume: 351 start-page: 668 year: 2004 ident: 10.1016/j.jaci.2021.07.035_bib20 article-title: Outcomes of allergy to insect stings in children, with and without venom immunotherapy publication-title: N Engl J Med doi: 10.1056/NEJMoa022952 – volume: 75 start-page: 2206 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib63 article-title: Global implementation of the World Health Organization’s International Classification of Diseases (ICD)-11: the allergic and hypersensitivity conditions model publication-title: Allergy doi: 10.1111/all.14468 – volume: 129 start-page: 748 year: 2012 ident: 10.1016/j.jaci.2021.07.035_bib64 article-title: Evaluation of National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network criteria for the diagnosis of anaphylaxis in emergency department patients publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2011.09.030 – volume: 147 start-page: 653 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib33 article-title: Phenotype and risk factors of venom-induced anaphylaxis: a case-control study of the European Anaphylaxis Registry publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2020.06.008 – volume: 147 start-page: 1123 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib24 article-title: Non--IgE-mediated anaphylaxis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2021.02.012 – volume: 9 start-page: 1826 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib55 article-title: An approach to the office-based practice of food oral immunotherapy publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2021.02.046 – volume: 3 start-page: 350 year: 2015 ident: 10.1016/j.jaci.2021.07.035_bib22 article-title: Epinephrine: a short history publication-title: Lancet Respir Med doi: 10.1016/S2213-2600(15)00087-9 – volume: 135 start-page: 956 year: 2015 ident: 10.1016/j.jaci.2021.07.035_bib23 article-title: Increase in anaphylaxis-related hospitalizations but no increase in fatalities: an analysis of United Kingdom national anaphylaxis data, 1992-2012 publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2014.10.021 – volume: 69 start-page: 1026 year: 2014 ident: 10.1016/j.jaci.2021.07.035_bib53 article-title: Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology publication-title: Allergy doi: 10.1111/all.12437 – volume: 130 start-page: 4759 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib67 article-title: Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis publication-title: J Clin Invest doi: 10.1172/JCI138448 – volume: 358 start-page: 28 year: 2008 ident: 10.1016/j.jaci.2021.07.035_bib15 article-title: Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis publication-title: N Engl J Med doi: 10.1056/NEJMoa070030 – volume: 148 start-page: 173 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib29 article-title: Severity grading system for acute allergic reactions: a multidisciplinary Delphi study publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2021.01.003 – volume: 30 start-page: 129 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib68 article-title: Precision medicine approaches to health disparities research publication-title: Ethn Dis doi: 10.18865/ed.30.S1.129 – volume: 7 start-page: 1148 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib50 article-title: Guiding principles for the recognition, diagnosis, and management of infants with anaphylaxis: an expert panel consensus publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2018.10.052 – volume: 365 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib35 article-title: Identification of a T follicular helper cell subset that drives anaphylactic IgE publication-title: Science doi: 10.1126/science.aaw6433 – volume: 8 start-page: 1169 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib3 article-title: Global trends in anaphylaxis epidemiology and clinical implications publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.11.027 – volume: 148 start-page: 83 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib31 article-title: Anaphylaxis – moving beyond severity… publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2021.04.017 – volume: 139 start-page: 1099 year: 2017 ident: 10.1016/j.jaci.2021.07.035_bib37 article-title: The microbiome in allergic disease: current understanding and future opportunities--2017 PRACTALL document of the American Academy of Allergy, Asthma and Immunology and the European Academy of Allergy and Clinical Immunology publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2017.02.007 – volume: 140 start-page: 321 year: 2017 ident: 10.1016/j.jaci.2021.07.035_bib13 article-title: Diagnosis and management of anaphylaxis in precision medicine publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2017.06.012 – volume: 146 start-page: 1089 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib28 article-title: Persistent, refractory, and biphasic anaphylaxis: a multidisciplinary Delphi study publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2020.08.015 – volume: 147 start-page: 622 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib38 article-title: Heritable risk for severe anaphylaxis associated with increased α-tryptase–encoding germline copy number at TPSAB1 publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2020.06.035 – volume: 148 start-page: 86 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib32 article-title: Commentary: severity grading system for acute allergic reactions. Time for validation and assessment of best practices publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2021.04.031 – volume: 13 start-page: 481 year: 2018 ident: 10.1016/j.jaci.2021.07.035_bib60 article-title: Intersection of mixed methods and community-based participatory research: a methodological review publication-title: J Mix Methods Res doi: 10.1177/1558689818778469 – volume: 4 start-page: 497 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib4 article-title: Safety, costs, and efficacy of rapid drug desensitizations to chemotherapy and monoclonal antibodies publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2015.12.019 – volume: 2 start-page: 414 year: 2014 ident: 10.1016/j.jaci.2021.07.035_bib6 article-title: Nonsteroidal anti-inflammatory drugs are major causes of drug-induced anaphylaxis publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2014.03.014 – volume: 127 start-page: 661 year: 2011 ident: 10.1016/j.jaci.2021.07.035_bib27 article-title: Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2011.01.031 – volume: 117 start-page: 391 year: 2006 ident: 10.1016/j.jaci.2021.07.035_bib1 article-title: Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2005.12.1303 – volume: 5 start-page: 1169 year: 2017 ident: 10.1016/j.jaci.2021.07.035_bib11 article-title: Fatal anaphylaxis: mortality rate and risk factors publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2017.06.031 – volume: 381 start-page: 2338 year: 2019 ident: 10.1016/j.jaci.2021.07.035_bib52 article-title: Penicillin allergy publication-title: N Engl J Med doi: 10.1056/NEJMra1807761 – volume: 132 start-page: 1141 year: 2013 ident: 10.1016/j.jaci.2021.07.035_bib16 article-title: Anaphylaxis: clinical patterns, mediator release, and severity publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2013.06.015 – volume: 163 start-page: 86 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib51 article-title: Evidence update for the treatment of anaphylaxis publication-title: Resuscitation doi: 10.1016/j.resuscitation.2021.04.010 – volume: 126 start-page: 168 year: 2021 ident: 10.1016/j.jaci.2021.07.035_bib48 article-title: Trends in US hospitalizations for anaphylaxis among infants and toddlers: 2006 to 2015 publication-title: Ann Allergy Asthma Immunol doi: 10.1016/j.anai.2020.09.003 – volume: 124 start-page: 473 year: 2020 ident: 10.1016/j.jaci.2021.07.035_bib34 article-title: Reaction phenotypes in IgE-mediated food allergy and anaphylaxis publication-title: Ann Allergy Asthma Immunol doi: 10.1016/j.anai.2019.12.023 – volume: 6 start-page: 620 year: 2016 ident: 10.1016/j.jaci.2021.07.035_bib42 article-title: Mast cell: a multi-functional master cell publication-title: Front Immunol doi: 10.3389/fimmu.2015.00620 – volume: 142 start-page: 159 year: 2018 ident: 10.1016/j.jaci.2021.07.035_bib5 article-title: Hypersensitivity reactions to therapeutic monoclonal antibodies: phenotypes and endotypes publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2018.02.018 – volume: 9 start-page: 1584 year: 2018 ident: 10.1016/j.jaci.2021.07.035_bib14 article-title: Microbiome and allergic diseases publication-title: Front Immunol doi: 10.3389/fimmu.2018.01584 |
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| SubjectTerms | Allergy anaphylaxis Anaphylaxis - diagnosis Anaphylaxis - epidemiology Anaphylaxis - prevention & control basic science Consensus emergency department feasibility Hospitalization Humans impact population science Surveys and Questionnaires translational science |
| Title | Anaphylaxis knowledge gaps and future research priorities: A consensus report |
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