Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo - Wible, Ryan S.; Tran, Quynh T.; Fathima, Samreen; Sutter, Carrie H.; Kensler, Thomas W.; Sutter, Thomas R. (Molecular pharmacology, 2018)
Keywords: Animals; Gene Regulatory Networks - drug effects; Gene Regulatory Networks - genetics; Imidazoles - metabolism; Imidazoles - pharmacology; Kelch-Like ECH-Associated Protein 1 - agonists; Kelch-Like ECH-Associated Protein 1 - genetics; Kelch-Like ECH-Associated Protein 1 - metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2 - agonists; NF-E2-Related Factor 2 - genetics; NF-E2-Related Factor 2 - metabolism; Oleanolic Acid - analogs & derivatives; Oleanolic Acid - metabolism; Oleanolic Acid - pharmacology; Pharmacogenetics - methods; Signal Transduction - drug effects; Signal Transduction - physiology; SREBP; D3T; CDDO-Im; aRNA; DAVID; GST; PKC; LSS; NQO; Nrf2; KEGG; qPCR; IPA; Wt