Two Innovative Approaches to Optimize Vancomycin Dosing Using Estimated AUC after First Dose: Validation Using Data Generated from Population PK Model Coupled with Monte-Carlo Simulation and Comparison with the First-Order PK Equation Approach - Liu, Qingxia; Huang, Huiping; Xu, Baohua; Li, Dandan; Liu, Maobai; Shaik, Imam H.; Wu, Xuemei (Pharmaceutics, 2022)
Keywords: Antibiotics; dose optimization; Monte Carlo simulation; Patients; Pharmacokinetics; pharmacokinetics/pharmacodynamics; Population; population pharmacokinetics; Software; Staphylococcus infections; vancomycin; vancomycin; dose optimization; Monte Carlo simulation; pharmacokinetics/pharmacodynamics; population pharmacokinetics