Parametric and Nonparametric Population Pharmacokinetic Models to Assess Probability of Target Attainment of Imipenem Concentrations in Critically Ill Patients - de Velde, Femke; de Winter, Brenda C. M.; Neely, Michael N.; Strojil, Jan; Yamada, Walter M.; Harbarth, Stephan; Huttner, Angela; van Gelder, Teun; Koch, Birgit C. P.; Muller, Anouk E. (Pharmaceutics, 2021)
Keywords: Antibiotics; Body mass index; Creatinine; Drug dosages; imipenem; nonparametric; Nonparametric statistics; parametric; Patients; Pharmacokinetics; Plasma; Population; population pharmacokinetic modeling; Simulation; simulations; imipenem; nonparametric; population pharmacokinetic modeling; parametric; simulations