A bioinformatician's guide to the forefront of suffix array construction algorithms

The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe Di...

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Published inBriefings in bioinformatics Vol. 15; no. 2; pp. 138 - 154
Main Authors Shrestha, A. M. S., Frith, M. C., Horton, P.
Format Journal Article
LanguageEnglish
Published England Oxford Publishing Limited (England) 01.03.2014
Oxford University Press
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Online AccessGet full text
ISSN1467-5463
1477-4054
1477-4054
DOI10.1093/bib/bbt081

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Abstract The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe DisLex, a technique that allows standard suffix array construction algorithms to create modified suffix arrays designed to enable a simple form of inexact matching needed to support 'spaced seeds' and 'subset seeds' used in many biological applications.
AbstractList The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe DisLex, a technique that allows standard suffix array construction algorithms to create modified suffix arrays designed to enable a simple form of inexact matching needed to support 'spaced seeds' and 'subset seeds' used in many biological applications.
The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe DisLex, a technique that allows standard suffix array construction algorithms to create modified suffix arrays designed to enable a simple form of inexact matching needed to support 'spaced seeds' and 'subset seeds' used in many biological applications. [PUBLICATION ABSTRACT]
The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe DisLex, a technique that allows standard suffix array construction algorithms to create modified suffix arrays designed to enable a simple form of inexact matching needed to support 'spaced seeds' and 'subset seeds' used in many biological applications.The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in mind, we provide an accessible exposition of the SA-IS algorithm, which is the state of the art in suffix array construction. We also describe DisLex, a technique that allows standard suffix array construction algorithms to create modified suffix arrays designed to enable a simple form of inexact matching needed to support 'spaced seeds' and 'subset seeds' used in many biological applications.
Author Shrestha, A. M. S.
Frith, M. C.
Horton, P.
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Issue 2
Keywords subset seeds
text index
spaced seeds
suffix array construction
linear-time algorithm
Language English
License This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
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Snippet The suffix array and its variants are text-indexing data structures that have become indispensable in the field of bioinformatics. With the uninitiated in...
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SubjectTerms Algorithms
Bioinformatics
Computational Biology - methods
Databases, Nucleic Acid - statistics & numerical data
Grammar
Humans
Pattern Recognition, Automated - statistics & numerical data
Software
Title A bioinformatician's guide to the forefront of suffix array construction algorithms
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