Double-hit B-cell lymphomas
In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint...
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| Published in | Blood Vol. 117; no. 8; pp. 2319 - 2331 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Washington, DC
Elsevier Inc
24.02.2011
Americain Society of Hematology |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0006-4971 1528-0020 1528-0020 |
| DOI | 10.1182/blood-2010-09-297879 |
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| Abstract | In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, mainly a t(14;18)(q32;q21) involving BCL2. Recently, these lymphomas have received increased attention, which contributed to the introduction of a novel category of lymphomas in the 2008 WHO classification, “B cell lymphoma unclassifiable with features intermediate between DLBCL and BL.” In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with their functions, as well as their pathology and clinical aspects including therapy and prognosis. The incidence of aggressive B-cell lymphomas other than Burkitt lymphoma with a MYC breakpoint and in particular a double hit is difficult to assess, because screening by methods like FISH has not been applied on large, unselected series, and the published cytogenetic data may be biased to specific categories of lymphomas. DH lymphomas have been classified heterogeneously but mostly as DLBCL, the majority having a germinal center phenotype and expression of BCL2. Patients with DH lymphomas often present with poor prognostic parameters, including elevated LDH, bone marrow and CNS involvement, and a high IPI score. All studies on larger series of patients suggest a poor prognosis, also if treated with RCHOP or high-intensity treatment modalities. Importantly, this poor outcome cannot be accounted for by the mere presence of a MYC/8q24 breakpoint. Likely, the combination of MYC and BCL2 expression and/or a related high genomic complexity are more important. Compared to these DH lymphomas, BCL6+/MYC+ DH lymphomas are far less common, and in fact most of these cases represent BCL2+/BCL6+/MYC+ triple-hit lymphomas with involvement of BCL2 as well. CCND1+/MYC+ DH lymphomas with involvement of 11q13 may also be relatively frequent, the great majority being classified as aggressive variants of mantle cell lymphoma. This suggests that activation of MYC might be an important progression pathway in mantle cell lymphoma as well. Based on clinical significance and the fact that no other solid diagnostic tools are available to identify DH lymphomas, it seems advisable to test all diffuse large B-cell and related lymphomas for MYC and other breakpoints. |
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| AbstractList | In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, mainly a t(14;18)(q32;q21) involving BCL2. Recently, these lymphomas have received increased attention, which contributed to the introduction of a novel category of lymphomas in the 2008 WHO classification, "B cell lymphoma unclassifiable with features intermediate between DLBCL and BL." In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with their functions, as well as their pathology and clinical aspects including therapy and prognosis. The incidence of aggressive B-cell lymphomas other than Burkitt lymphoma with a MYC breakpoint and in particular a double hit is difficult to assess, because screening by methods like FISH has not been applied on large, unselected series, and the published cytogenetic data may be biased to specific categories of lymphomas. DH lymphomas have been classified heterogeneously but mostly as DLBCL, the majority having a germinal center phenotype and expression of BCL2. Patients with DH lymphomas often present with poor prognostic parameters, including elevated LDH, bone marrow and CNS involvement, and a high IPI score. All studies on larger series of patients suggest a poor prognosis, also if treated with RCHOP or high-intensity treatment modalities. Importantly, this poor outcome cannot be accounted for by the mere presence of a MYC/8q24 breakpoint. Likely, the combination of MYC and BCL2 expression and/or a related high genomic complexity are more important. Compared to these DH lymphomas, BCL6(+)/MYC(+) DH lymphomas are far less common, and in fact most of these cases represent BCL2(+)/BCL6(+)/MYC(+) triple-hit lymphomas with involvement of BCL2 as well. CCND1(+)/MYC(+) DH lymphomas with involvement of 11q13 may also be relatively frequent, the great majority being classified as aggressive variants of mantle cell lymphoma. This suggests that activation of MYC might be an important progression pathway in mantle cell lymphoma as well. Based on clinical significance and the fact that no other solid diagnostic tools are available to identify DH lymphomas, it seems advisable to test all diffuse large B-cell and related lymphomas for MYC and other breakpoints. In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, mainly a t(14;18)(q32;q21) involving BCL2. Recently, these lymphomas have received increased attention, which contributed to the introduction of a novel category of lymphomas in the 2008 WHO classification, "B cell lymphoma unclassifiable with features intermediate between DLBCL and BL." In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with their functions, as well as their pathology and clinical aspects including therapy and prognosis. The incidence of aggressive B-cell lymphomas other than Burkitt lymphoma with a MYC breakpoint and in particular a double hit is difficult to assess, because screening by methods like FISH has not been applied on large, unselected series, and the published cytogenetic data may be biased to specific categories of lymphomas. DH lymphomas have been classified heterogeneously but mostly as DLBCL, the majority having a germinal center phenotype and expression of BCL2. Patients with DH lymphomas often present with poor prognostic parameters, including elevated LDH, bone marrow and CNS involvement, and a high IPI score. All studies on larger series of patients suggest a poor prognosis, also if treated with RCHOP or high-intensity treatment modalities. Importantly, this poor outcome cannot be accounted for by the mere presence of a MYC/8q24 breakpoint. Likely, the combination of MYC and BCL2 expression and/or a related high genomic complexity are more important. Compared to these DH lymphomas, BCL6(+)/MYC(+) DH lymphomas are far less common, and in fact most of these cases represent BCL2(+)/BCL6(+)/MYC(+) triple-hit lymphomas with involvement of BCL2 as well. CCND1(+)/MYC(+) DH lymphomas with involvement of 11q13 may also be relatively frequent, the great majority being classified as aggressive variants of mantle cell lymphoma. This suggests that activation of MYC might be an important progression pathway in mantle cell lymphoma as well. Based on clinical significance and the fact that no other solid diagnostic tools are available to identify DH lymphomas, it seems advisable to test all diffuse large B-cell and related lymphomas for MYC and other breakpoints.In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, mainly a t(14;18)(q32;q21) involving BCL2. Recently, these lymphomas have received increased attention, which contributed to the introduction of a novel category of lymphomas in the 2008 WHO classification, "B cell lymphoma unclassifiable with features intermediate between DLBCL and BL." In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with their functions, as well as their pathology and clinical aspects including therapy and prognosis. The incidence of aggressive B-cell lymphomas other than Burkitt lymphoma with a MYC breakpoint and in particular a double hit is difficult to assess, because screening by methods like FISH has not been applied on large, unselected series, and the published cytogenetic data may be biased to specific categories of lymphomas. DH lymphomas have been classified heterogeneously but mostly as DLBCL, the majority having a germinal center phenotype and expression of BCL2. Patients with DH lymphomas often present with poor prognostic parameters, including elevated LDH, bone marrow and CNS involvement, and a high IPI score. All studies on larger series of patients suggest a poor prognosis, also if treated with RCHOP or high-intensity treatment modalities. Importantly, this poor outcome cannot be accounted for by the mere presence of a MYC/8q24 breakpoint. Likely, the combination of MYC and BCL2 expression and/or a related high genomic complexity are more important. Compared to these DH lymphomas, BCL6(+)/MYC(+) DH lymphomas are far less common, and in fact most of these cases represent BCL2(+)/BCL6(+)/MYC(+) triple-hit lymphomas with involvement of BCL2 as well. CCND1(+)/MYC(+) DH lymphomas with involvement of 11q13 may also be relatively frequent, the great majority being classified as aggressive variants of mantle cell lymphoma. This suggests that activation of MYC might be an important progression pathway in mantle cell lymphoma as well. Based on clinical significance and the fact that no other solid diagnostic tools are available to identify DH lymphomas, it seems advisable to test all diffuse large B-cell and related lymphomas for MYC and other breakpoints. |
| Author | van Imhoff, Gustaaf W. Siebert, Reiner Boerma, Evert-Jan Kluin-Nelemans, Hanneke C. Aukema, Sietse M. Kluin, Philip M. Schuuring, Ed |
| Author_xml | – sequence: 1 givenname: Sietse M. surname: Aukema fullname: Aukema, Sietse M. email: s.m.aukema@student.rug.nl organization: Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands – sequence: 2 givenname: Reiner surname: Siebert fullname: Siebert, Reiner organization: Institute of Human Genetics, Christian-Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany – sequence: 3 givenname: Ed surname: Schuuring fullname: Schuuring, Ed organization: Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands – sequence: 4 givenname: Gustaaf W. surname: van Imhoff fullname: van Imhoff, Gustaaf W. organization: Department of Hematology, University Medical Center Groningen, University of Groningen, The Netherlands; and – sequence: 5 givenname: Hanneke C. surname: Kluin-Nelemans fullname: Kluin-Nelemans, Hanneke C. organization: Department of Hematology, University Medical Center Groningen, University of Groningen, The Netherlands; and – sequence: 6 givenname: Evert-Jan surname: Boerma fullname: Boerma, Evert-Jan organization: Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands – sequence: 7 givenname: Philip M. surname: Kluin fullname: Kluin, Philip M. organization: Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands |
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| Cites_doi | 10.1111/j.1600-0609.2004.00338.x 10.1038/modpathol.3800500 10.1111/j.1365-2141.2010.08159.x 10.1056/NEJMoa055351 10.1038/sj.onc.1204641 10.1056/NEJM198805263182106 10.1073/pnas.94.13.6658 10.1182/blood-2008-01-136465 10.1182/blood-2009-06-227017 10.1084/jem.20062104 10.1182/blood.V95.11.3520 10.3324/haematol.11305 10.1126/science.3929382 10.1182/blood.V86.1.45.bloodjournal86145 10.1038/nature03147 10.1016/S1074-7613(00)80291-5 10.1073/pnas.90.7.2935 10.1080/10428190701836845 10.1016/S0165-4608(00)00383-6 10.1309/NKK3FEX2BE5L7EKB 10.1038/nature08159 10.1182/blood-2009-05-220095 10.1172/JCI113235 10.1038/sj.leu.2404035 10.1002/j.1460-2075.1994.tb06488.x 10.1002/j.1460-2075.1988.tb02791.x 10.1016/0092-8674(89)90174-8 10.1182/blood.V85.9.2528.bloodjournal8592528 10.1182/blood.V88.4.1177.bloodjournal8841177 10.2174/156652408785747988 10.1002/path.2410 10.1073/pnas.92.14.6577 10.3324/haematol.2009.013177 10.1093/ajcp/112.6.828 10.1038/leu.2008.102 10.1200/JCO.2006.08.7999 10.3109/10428190109097743 10.1038/sj.leu.2404529 10.1016/j.cell.2008.10.035 10.1182/blood-2007-01-069575 10.1073/pnas.84.24.9257 10.1182/blood-2008-03-145128 10.1073/pnas.86.12.4589 10.3324/haematol.13220 10.1097/PAS.0b013e3181cd3aeb 10.1002/gcc.20609 10.1038/ng0697-161 10.1016/j.molcel.2007.12.029 10.1084/jem.20070884 10.1097/01.pas.0000168176.71405.e5 10.3324/haematol.2008.005355 10.1038/sj.leu.2404695 10.1016/S1535-6108(03)00028-X 10.1056/NEJMoa055759 10.1182/blood.V99.2.716 10.1038/sj.onc.1201156 10.1084/jem.20082271 10.1126/science.6093263 10.1097/00001622-200109000-00002 10.3324/haematol.13190 10.1038/349254a0 10.1016/j.cell.2008.09.062 10.1182/blood.V80.3.758.758 10.1182/blood.V84.5.1361.1361 10.1182/blood.V99.9.3376 10.1002/gcc.2870030304 10.1136/jcp.2009.065227 10.1097/01.MP.0000037310.82136.99 10.1126/science.2251503 10.1084/jem.169.3.613 10.1002/j.1460-2075.1994.tb06655.x 10.1038/leu.2009.31 10.1016/j.semcancer.2006.07.014 10.1016/S1074-7613(00)00020-0 10.1038/modpathol.2010.76 10.1002/(SICI)1098-2264(199709)20:1<64::AID-GCC10>3.0.CO;2-F 10.1200/JCO.2009.22.7058 10.1038/leu.2008.281 10.1038/348331a0 10.1309/EQJR3D3V0CCQGP04 10.1016/0165-4608(84)90084-0 10.1002/j.1460-2075.1995.tb00311.x 10.1073/pnas.0804295105 10.4049/jimmunol.173.2.1158 10.1007/s00277-004-0855-x 10.1126/science.276.5312.589 10.1016/j.molcel.2009.11.007 10.1016/j.ccr.2007.08.011 10.1111/j.1349-7006.2008.01035.x 10.1038/sj.onc.1201771 10.1200/JCO.2009.26.3947 10.1182/blood-2008-12-193037 10.1200/JCO.2006.05.5897 10.1182/blood.V99.12.4265 10.1080/10428190290016890 10.1080/10428190600612909 10.1126/science.2006410 10.3324/haematol.13071 10.1080/10428190701852024 10.1200/JCO.1999.17.5.1558 10.1182/blood.V86.1.28.bloodjournal86128 10.1016/j.dnarep.2006.05.012 10.1093/oxfordjournals.annonc.a010568 10.1111/j.1365-2559.2008.03076.x 10.1038/leu.2008.230 10.1111/j.1365-2141.2010.08111.x 10.1038/ng.2007.30 10.1093/jncimonographs/lgn020 10.1182/blood-2009-03-212191 10.1073/pnas.0903854106 10.1016/j.cell.2004.08.006 10.1016/0092-8674(90)90347-H 10.1038/leu.2008.344 10.1016/j.ccr.2005.03.037 10.1038/nature03677 10.1073/pnas.0437996100 10.1093/jncimonographs/lgn015 10.1016/j.humpath.2008.06.032 10.1097/PAS.0b013e3181f3e29f 10.1080/10428190410001711479 10.1084/jem.20061292 |
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| Keywords | Malignant hemopathy B-Lymphocyte Hematology Lymphoma Lymphoproliferative syndrome Cancer |
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| References | Tsai, Lu, Raghavan, Muschen, Hsieh, Lieber (bib50) 2008; 135 Mohamed, Palutke, Eisenberg, Al Katib (bib106) 2001; 126 Bhatia, Huppi, McKeithan, Siwarski, Mushinski, Magrath (bib85) 1991; 6 Avet-Loiseau, Li, Facon (bib78) 1998; 58 Oschlies, Salaverria, Mahn (bib113) 2010; 95 Shim, Dolde, Lewis (bib25) 1997; 94 McKeithan, Takimoto, Ohno (bib92) 1997; 20 Kienle, Katzenberger, Ott (bib121) 2007; 25 Dent, Shaffer, Yu, Allman, Staudt (bib67) 1997; 276 Fenton, Vaandrager, Aarts (bib47) 2002; 99 Macpherson, Lesack, Klasa (bib112) 1999; 17 Ong, Hackbarth, Degenstein, Baunoch, Anastasi, McKeithan (bib93) 1998; 16 Klein, Tu, Stolovitzky (bib29) 2003; 100 Jerkeman, Anderson, Dictor, Kvaloy, Akerman, Cavallin-Stahl (bib123) 2004; 83 Janssen, Vaandrager, Heuser (bib84) 2000; 95 Boerma, Siebert, Kluin, Baudis (bib95) 2009; 23 Cattoretti, Chang, Cechova (bib64) 1995; 86 Ramiro, Jankovic, Eisenreich (bib31) 2004; 118 Mead, Barrans, Qian (bib115) 2008; 112 Limpens, Stad, Vos (bib57) 1995; 85 Klapper, Szczepanowski, Burkhardt (bib122) 2008; 112 Yoon, Jeon, Paik (bib129) 2008; 53 Offit, Jhanwar, Ladanyi, Filippa, Chaganti (bib3) 1991; 3 Onizuka, Moriyama, Yamochi (bib65) 1995; 86 Strasser, Harris, Bath, Cory (bib62) 1990; 348 (bib8) 2010 Bergsagel, Kuehl (bib17) 2001; 20 Copie-Bergman, Gaulard, Leroy (bib132) 2009; 27 Wang, Gao, May, Zhang, Flagg, Deng (bib46) 2008; 29 Muller, Janz, Goedert, Potter, Rabkin (bib38) 1995; 92 Leucci, Cocco, Onnis (bib127) 2008; 216 Niitsu, Okamoto, Miura, Hirano (bib117) 2009; 100 Bertrand, Maingonnat, Ruminy, Tilly, Bastard (bib20) 2007; 92 Hummel, Bentink, Berger (bib109) 2006; 354 Yunis, Oken, Theologides, Howe, Kaplan (bib2) 1984; 13 Phan, Dalla-Favera (bib73) 2004; 432 Janz (bib37) 2008 Harris, Jaffe, Stein (bib9) 1994; 84 Ohno, Doi, Yabumoto, Fukuhara, McKeithan (bib91) 1993; 7 de Boer, Kluin-Nelemans, Dreef (bib81) 1996; 7 Nunez, Seto, Seremetis (bib56) 1989; 86 van Imhoff, Boerma, van der Holt (bib133) 2006; 24 Chang, Yu, Lee (bib27) 2008; 40 Hardianti, Tatsumi, Syampurnawati (bib102) 2005; 74 Saito, Novak, Piovan (bib43) 2009; 106 Kuo, Shaffer, Haddad, Choi, Staudt, Calame (bib71) 2007; 204 Gabrea, Leif Bergsagel, Michael Kuehl (bib16) 2006; 5 Gauwerky, Hoxie, Nowell, Croce (bib100) 1988; 2 Yano, Jaffe, Longo, Raffeld (bib105) 1992; 80 Dave, Fu, Wright (bib110) 2006; 354 Roulland, Navarro, Grenot (bib60) 2006; 203 Basso, Saito, Sumazin (bib68) 2010; 115 Jager, Bocskor, Le (bib51) 2000; 95 Klapper, Stoecklein, Zeynalova (bib108) 2008; 22 Le Gouill, Talmant, Touzeau (bib10) 2007; 92 Cong, Raffeld, Teruya-Feldstein, Sorbara, Pittaluga, Jaffe (bib61) 2002; 99 Felten, Stephenson, Ortiz, Hertzberg (bib99) 2004; 45 Robertus, Kluiver, Weggemans (bib26) 2010; 149 Tsujimoto, Finger, Yunis, Nowell, Croce (bib41) 1984; 226 Lenz, Wright, Emre (bib107) 2008; 105 Tunyaplin, Shaffer, Angelin-Duclos, Yu, Staudt, Calame (bib72) 2004; 173 Roulland, Lebailly, Lecluse, Heutte, Nadel, Gauduchon (bib58) 2006; 20 Ohno, Takimoto, McKeithan (bib87) 1990; 60 Roschke, Kopantzev, Dertzbaugh, Rudikoff (bib39) 1997; 14 Cattoretti, Pasqualucci, Ballon (bib76) 2005; 7 Tsujimoto, Gorham, Cossman, Jaffe, Croce (bib49) 1985; 229 Obermann, Csato, Dirnhofer, Tzankov (bib130) 2009; 62 Bertrand, Bastard, Maingonnat (bib40) 2007; 21 Au, Gascoyne, Viswanatha, Connors, Klasa, Horsman (bib79) 2002; 43 Avet-Loiseau (bib19) 2007; 92 Kobrin, Cha, Qin (bib103) 2006; 47 Lecluse, Lebailly, Roulland, Gac, Nadel, Gauduchon (bib83) 2009; 23 Seto, Jaeger, Hockett (bib45) 1988; 7 Rosenwald, Wright, Wiestner (bib120) 2003; 3 Chuang, Ye, Du (bib125) 2007; 128 Gu, Cechova, Tassi, Dalla-Favera (bib24) 1993; 90 De Jong, Voetdijk, van Ommen, Kluin-Nelemans, Beverstock, Kluin (bib94) 1989; 169 Kluin, Harris, Stein (bib6) 2008 Lovec, Grzeschiczek, Kowalski, Moroy (bib97) 1994; 13 Blackwood, Eisenman (bib22) 1991; 251 Ci, Polo, Cerchietti (bib44) 2009; 113 Franzoso, Carlson, Scharton-Kersten (bib86) 1997; 6 Niitsu, Okamoto, Miura, Hirano (bib12) 2009; 23 Chapiro, Radford-Weiss, Bastard (bib88) 2008; 22 Ye, Cattoretti, Shen (bib66) 1997; 16 Siebert (bib4) 2009 Robbiani, Bothmer, Callen (bib34) 2008; 135 Wang, Gostissa, Yan (bib53) 2009; 460 Valera, Balague, Colomo (bib18) 2010; 34 Shaffer, Yu, He, Boldrick, Chan, Staudt (bib70) 2000; 13 Bodrug, Warner, Bath, Lindeman, Harris, Adams (bib96) 1994; 13 Blackwell, Kretzner, Blackwood, Eisenman, Weintraub (bib23) 1990; 250 Martin-Subero, Ibbotson, Klapper (bib89) 2007; 21 Robbiani, Bunting, Feldhahn (bib33) 2009; 36 De Jong, Voetdijk, Beverstock, van Ommen, Willemze, Kluin (bib48) 1988; 318 Tibiletti, Martin, Bernasconi (bib131) 2009; 40 Klapproth, Wirth (bib30) 2010; 149 Ye, Chaganti, Chang (bib74) 1995; 14 Kanungo, Medeiros, Abruzzo, Lin (bib13) 2006; 19 McKeithan, Rowley, Shows, Diaz (bib90) 1987; 84 Savage, Johnson, Ben Neriah (bib128) 2009; 114 Prochownik (bib36) 2008; 8 McDonnell, Korsmeyer (bib63) 1991; 349 Bloomfield, Arthur, Frizzera, Levine, Peterson, Gajl-Peczalska (bib1) 1983; 43 Parekh, Polo, Shaknovich (bib69) 2007; 110 Welzel, Le, Marculescu (bib82) 2001; 61 Roulland, Lebailly, Gauduchon (bib59) 2003; 63 Saito, Gao, Basso (bib75) 2007; 12 Christie, Kernohan, Levison (bib104) 2008; 49 Siebert, Rosenwald, Staudt, Morris (bib5) 2001; 13 Dorsett, Robbiani, Jankovic, Reina-San-Martin, Eisenreich, Nussenzweig (bib32) 2007; 204 Nadel, Marculescu, Le, Rudnicki, Bocskor, Jager (bib52) 2001; 42 Hao, Sanger, Onciu, Lai, Schlette, Medeiros (bib118) 2002; 15 Haralambieva, Boerma, van Imhoff (bib124) 2005; 29 Lin, O'Brien, Faber (bib126) 1999; 112 Tomita, Tokunaka, Nakamura (bib11) 2009; 94 Snuderl, Kolman, Chen (bib14) 2010; 34 Seegmiller, Garcia, Huang, Maleki, Karandikar, Chen (bib116) 2010; 23 Graninger, Seto, Boutain, Goldman, Korsmeyer (bib42) 1987; 80 Guikema, Schuuring, Kluin (bib35) 2008 Salaverria, Zettl, Bea (bib111) 2008; 93 McDonnell, Deane, Platt (bib55) 1989; 57 Reddy, Ansari-Lari, Dipasquale (bib119) 2008; 49 Dang, O'Donnell, Zeller, Nguyen, Osthus, Li (bib21) 2006; 16 Johnson, Savage, Ludkovski (bib15) 2009; 114 Biagi, Seymour (bib7) 2002; 99 O'Donnell, Wentzel, Zeller, Dang, Mendell (bib28) 2005; 435 Young, Xie, Zhou (bib101) 2008; 129 Salaverria, Espinet, Carrio (bib80) 2008; 47 Barrans, Crouch, Smith (bib114) 2010; 28 Au, Horsman, Viswanatha, Connors, Klasa, Gascoyne (bib98) 2000; 85 Wang, Alt, Gostissa (bib54) 2008; 205 Vaandrager, Schuuring, Zwikstra (bib77) 1996; 88 Oschlies (2019111810181455200_B113) 2010; 95 Christie (2019111810181455200_B104) 2008; 49 Tomita (2019111810181455200_B11) 2009; 94 McKeithan (2019111810181455200_B92) 1997; 20 Dorsett (2019111810181455200_B32) 2007; 204 Janz (2019111810181455200_B37) 2008 Tsujimoto (2019111810181455200_B41) 1984; 226 Yoon (2019111810181455200_B129) 2008; 53 Robbiani (2019111810181455200_B34) 2008; 135 Ci (2019111810181455200_B44) 2009; 113 Shaffer (2019111810181455200_B70) 2000; 13 Muller (2019111810181455200_B38) 1995; 92 Bodrug (2019111810181455200_B96) 1994; 13 Copie-Bergman (2019111810181455200_B132) 2009; 27 Fenton (2019111810181455200_B47) 2002; 99 McKeithan (2019111810181455200_B90) 1987; 84 Phan (2019111810181455200_B73) 2004; 432 Boerma (2019111810181455200_B95) 2009; 23 Hummel (2019111810181455200_B109) 2006; 354 Lecluse (2019111810181455200_B83) 2009; 23 Vaandrager (2019111810181455200_B77) 1996; 88 Tunyaplin (2019111810181455200_B72) 2004; 173 Salaverria (2019111810181455200_B111) 2008; 93 Savage (2019111810181455200_B128) 2009; 114 Young (2019111810181455200_B101) 2008; 129 Prochownik (2019111810181455200_B36) 2008; 8 Harris (2019111810181455200_B9) 1994; 84 Salaverria (2019111810181455200_B80) 2008; 47 Chang (2019111810181455200_B27) 2008; 40 Hardianti (2019111810181455200_B102) 2005; 74 Hao (2019111810181455200_B118) 2002; 15 Leucci (2019111810181455200_B127) 2008; 216 Bertrand (2019111810181455200_B40) 2007; 21 Dave (2019111810181455200_B110) 2006; 354 Gabrea (2019111810181455200_B16) 2006; 5 Ye (2019111810181455200_B66) 1997; 16 Tsai (2019111810181455200_B50) 2008; 135 Roulland (2019111810181455200_B59) 2003; 63 Chuang (2019111810181455200_B125) 2007; 128 van Imhoff (2019111810181455200_B133) 2006; 24 Robertus (2019111810181455200_B26) 2010; 149 Basso (2019111810181455200_B68) 2010; 115 Ramiro (2019111810181455200_B31) 2004; 118 Kienle (2019111810181455200_B121) 2007; 25 Cong (2019111810181455200_B61) 2002; 99 Gu (2019111810181455200_B24) 1993; 90 Dent (2019111810181455200_B67) 1997; 276 Ohno (2019111810181455200_B91) 1993; 7 Welzel (2019111810181455200_B82) 2001; 61 Ong (2019111810181455200_B93) 1998; 16 Lenz (2019111810181455200_B107) 2008; 105 Niitsu (2019111810181455200_B117) 2009; 100 Lin (2019111810181455200_B126) 1999; 112 Franzoso (2019111810181455200_B86) 1997; 6 Niitsu (2019111810181455200_B12) 2009; 23 Onizuka (2019111810181455200_B65) 1995; 86 Le Gouill (2019111810181455200_B10) 2007; 92 Roulland (2019111810181455200_B60) 2006; 203 Dang (2019111810181455200_B21) 2006; 16 McDonnell (2019111810181455200_B63) 1991; 349 2019111810181455200_B8 Roschke (2019111810181455200_B39) 1997; 14 Wang (2019111810181455200_B54) 2008; 205 Klapproth (2019111810181455200_B30) 2010; 149 Au (2019111810181455200_B79) 2002; 43 Shim (2019111810181455200_B25) 1997; 94 Snuderl (2019111810181455200_B14) 2010; 34 Felten (2019111810181455200_B99) 2004; 45 Bergsagel (2019111810181455200_B17) 2001; 20 Janssen (2019111810181455200_B84) 2000; 95 Offit (2019111810181455200_B3) 1991; 3 Klein (2019111810181455200_B29) 2003; 100 Seto (2019111810181455200_B45) 1988; 7 Jerkeman (2019111810181455200_B123) 2004; 83 Guikema (2019111810181455200_B35) 2008 Lovec (2019111810181455200_B97) 1994; 13 de Boer (2019111810181455200_B81) 1996; 7 Saito (2019111810181455200_B75) 2007; 12 Nunez (2019111810181455200_B56) 1989; 86 Avet-Loiseau (2019111810181455200_B78) 1998; 58 Strasser (2019111810181455200_B62) 1990; 348 Obermann (2019111810181455200_B130) 2009; 62 O'Donnell (2019111810181455200_B28) 2005; 435 Au (2019111810181455200_B98) 2000; 85 Seegmiller (2019111810181455200_B116) 2010; 23 Kuo (2019111810181455200_B71) 2007; 204 Blackwell (2019111810181455200_B23) 1990; 250 Bhatia (2019111810181455200_B85) 1991; 6 Reddy (2019111810181455200_B119) 2008; 49 Klapper (2019111810181455200_B122) 2008; 112 Biagi (2019111810181455200_B7) 2002; 99 Avet-Loiseau (2019111810181455200_B19) 2008; 93 McDonnell (2019111810181455200_B55) 1989; 57 Yano (2019111810181455200_B105) 1992; 80 De Jong (2019111810181455200_B94) 1989; 169 Parekh (2019111810181455200_B69) 2007; 110 Cattoretti (2019111810181455200_B76) 2005; 7 Graninger (2019111810181455200_B42) 1987; 80 Kobrin (2019111810181455200_B103) 2006; 47 Macpherson (2019111810181455200_B112) 1999; 17 Jager (2019111810181455200_B51) 2000; 95 Ohno (2019111810181455200_B87) 1990; 60 Bertrand (2019111810181455200_B20) 2008; 93 Ye (2019111810181455200_B74) 1995; 14 Wang (2019111810181455200_B46) 2008; 29 Wang (2019111810181455200_B53) 2009; 460 Cattoretti (2019111810181455200_B64) 1995; 86 Blackwood (2019111810181455200_B22) 1991; 251 Roulland (2019111810181455200_B58) 2006; 20 Martin-Subero (2019111810181455200_B89) 2007; 21 Kanungo (2019111810181455200_B13) 2006; 19 Valera (2019111810181455200_B18) 2010; 34 Nadel (2019111810181455200_B52) 2001; 42 Rosenwald (2019111810181455200_B120) 2003; 3 Saito (2019111810181455200_B43) 2009; 106 Siebert (2019111810181455200_B5) 2001; 13 Mohamed (2019111810181455200_B106) 2001; 126 Tibiletti (2019111810181455200_B131) 2009; 40 Robbiani (2019111810181455200_B33) 2009; 36 Siebert (2019111810181455200_B4) 2009 Kluin (2019111810181455200_B6) 2008 Limpens (2019111810181455200_B57) 1995; 85 Gauwerky (2019111810181455200_B100) 1988; 2 Bloomfield (2019111810181455200_B1) 1983; 43 Johnson (2019111810181455200_B15) 2009; 114 Tsujimoto (2019111810181455200_B49) 1985; 229 Mead (2019111810181455200_B115) 2008; 112 Klapper (2019111810181455200_B108) 2008; 22 De Jong (2019111810181455200_B48) 1988; 318 Haralambieva (2019111810181455200_B124) 2005; 29 Chapiro (2019111810181455200_B88) 2008; 22 Yunis (2019111810181455200_B2) 1984; 13 Barrans (2019111810181455200_B114) 2010; 28 |
| References_xml | – volume: 95 start-page: 2691 year: 2000 end-page: 2698 ident: bib84 article-title: Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32) publication-title: Blood – volume: 8 start-page: 446 year: 2008 end-page: 458 ident: bib36 article-title: c-Myc: linking transformation and genomic instability publication-title: Curr Mol Med – volume: 53 start-page: 205 year: 2008 end-page: 217 ident: bib129 article-title: MYC translocation and an increased copy number predict poor prognosis in adult diffuse large B-cell lymphoma (DLBCL), especially in germinal centre-like B cell (GCB) type publication-title: Histopathology – volume: 7 start-page: 251 year: 1996 end-page: 256 ident: bib81 article-title: Involvement of the CCND1 gene in hairy cell leukemia publication-title: Ann Oncol – volume: 149 start-page: 484 year: 2010 end-page: 497 ident: bib30 article-title: Advances in the understanding of MYC-induced lymphomagenesis publication-title: Br J Haematol – volume: 6 start-page: 1569 year: 1991 end-page: 1573 ident: bib85 article-title: Mouse bcl-3: cDNA structure, mapping and stage-dependent expression in B lymphocytes publication-title: Oncogene – volume: 74 start-page: 11 year: 2005 end-page: 19 ident: bib102 article-title: Presence of somatic hypermutation and activation-induced cytidine deaminase in acute lymphoblastic leukemia L2 with t(14;18)(q32;q21) publication-title: Eur J Haematol – volume: 47 start-page: 1523 year: 2006 end-page: 1534 ident: bib103 article-title: Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis publication-title: Leuk Lymphoma – volume: 99 start-page: 716 year: 2002 end-page: 718 ident: bib47 article-title: Follicular lymphoma with a novel t(14;18) breakpoint involving the immunoglobulin heavy chain switch mu region indicates an origin from germinal center B cells publication-title: Blood – volume: 7 start-page: 2057 year: 1993 end-page: 2063 ident: bib91 article-title: Molecular characterization of the t(14;19)(q32;q13) translocation in chronic lymphocytic leukemia publication-title: Leukemia – volume: 204 start-page: 2225 year: 2007 end-page: 2232 ident: bib32 article-title: A role for AID in chromosome translocations between c-myc and the IgH variable region publication-title: J Exp Med – volume: 93 start-page: 1327 year: 2008 end-page: 1334 ident: bib111 article-title: Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma publication-title: Haematologica – year: 2009 ident: bib4 article-title: Mature B- and T-cell neoplasms and Hodgkin lymphomas publication-title: Cancer Cytogenetics – start-page: 37 year: 2008 end-page: 40 ident: bib37 article-title: Genetic and environmental cofactors of Myc translocations in plasma cell tumor development in mice publication-title: J Natl Cancer Inst Monogr – volume: 21 start-page: 515 year: 2007 end-page: 523 ident: bib40 article-title: Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas publication-title: Leukemia – volume: 92 start-page: 1335 year: 2007 end-page: 1342 ident: bib20 article-title: Comment to: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement publication-title: Haematologica – volume: 204 start-page: 819 year: 2007 end-page: 830 ident: bib71 article-title: Repression of BCL-6 is required for the formation of human memory B cells in vitro publication-title: J Exp Med – volume: 34 start-page: 327 year: 2010 end-page: 340 ident: bib14 article-title: B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma publication-title: Am J Surg Pathol – volume: 229 start-page: 1390 year: 1985 end-page: 1393 ident: bib49 article-title: The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining publication-title: Science – volume: 42 start-page: 1181 year: 2001 end-page: 1194 ident: bib52 article-title: Novel insights into the mechanism of t(14;18)(q32;q21) translocation in follicular lymphoma publication-title: Leuk Lymphoma – volume: 112 start-page: 828 year: 1999 end-page: 835 ident: bib126 article-title: De novo CD5+ Burkitt lymphoma/leukemia publication-title: Am J Clin Pathol – volume: 20 start-page: 158 year: 2006 end-page: 162 ident: bib58 article-title: Long-term clonal persistence and evolution of t(14;18)-bearing B cells in healthy individuals publication-title: Leukemia – volume: 100 start-page: 2639 year: 2003 end-page: 2644 ident: bib29 article-title: Transcriptional analysis of the B cell germinal center reaction publication-title: Proc Natl Acad Sci U S A – volume: 80 start-page: 1512 year: 1987 end-page: 1515 ident: bib42 article-title: Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells publication-title: J Clin Invest – volume: 86 start-page: 45 year: 1995 end-page: 53 ident: bib64 article-title: BCL-6 protein is expressed in germinal-center B cells publication-title: Blood – volume: 17 start-page: 1558 year: 1999 end-page: 1567 ident: bib112 article-title: Small noncleaved, non-Burkitt's (Burkit-Like) lymphoma: cytogenetics predict outcome and reflect clinical presentation publication-title: J Clin Oncol – volume: 90 start-page: 2935 year: 1993 end-page: 2939 ident: bib24 article-title: Opposite regulation of gene transcription and cell proliferation by c-Myc and Max publication-title: Proc Natl Acad Sci U S A – volume: 432 start-page: 635 year: 2004 end-page: 639 ident: bib73 article-title: The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells publication-title: Nature – volume: 95 start-page: 253 year: 2010 end-page: 259 ident: bib113 article-title: Pediatric follicular lymphoma–a clinico-pathological study of a population-based series of patients treated within the Non-Hodgkin's Lymphoma–Berlin-Frankfurt-Munster (NHL-BFM) multicenter trials publication-title: Haematologica – volume: 88 start-page: 1177 year: 1996 end-page: 1182 ident: bib77 article-title: Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization publication-title: Blood – volume: 250 start-page: 1149 year: 1990 end-page: 1151 ident: bib23 article-title: Sequence-specific DNA binding by the c-Myc protein publication-title: Science – volume: 16 start-page: 161 year: 1997 end-page: 170 ident: bib66 article-title: The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation publication-title: Nat Genet – volume: 23 start-page: 777 year: 2009 end-page: 783 ident: bib12 article-title: Clinical features and prognosis of de novo diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC translocations publication-title: Leukemia – volume: 61 start-page: 1629 year: 2001 end-page: 1636 ident: bib82 article-title: Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma publication-title: Cancer Res – volume: 3 start-page: 185 year: 2003 end-page: 197 ident: bib120 article-title: The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma publication-title: Cancer Cell – volume: 14 start-page: 6209 year: 1995 end-page: 6217 ident: bib74 article-title: Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma publication-title: EMBO J – volume: 129 start-page: 157 year: 2008 end-page: 166 ident: bib101 article-title: Transformation of follicular lymphoma to precursor B-cell lymphoblastic lymphoma with c-myc gene rearrangement as a critical event publication-title: Am J Clin Pathol – volume: 112 start-page: 2248 year: 2008 end-page: 2260 ident: bib115 article-title: A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic Burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial) publication-title: Blood – volume: 99 start-page: 4265 year: 2002 end-page: 4275 ident: bib7 article-title: Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation publication-title: Blood – volume: 169 start-page: 613 year: 1989 end-page: 624 ident: bib94 article-title: Translocation t(14;18) in B cell lymphomas as a cause for defective immunoglobulin production publication-title: J Exp Med – volume: 92 start-page: 1335 year: 2007 end-page: 1342 ident: bib19 article-title: Reply to: Comment to: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement publication-title: Haematologica – volume: 2 start-page: 431 year: 1988 end-page: 435 ident: bib100 article-title: Pre-B-cell leukemia with a t(8; 14) and a t(14; 18) translocation is preceded by follicular lymphoma publication-title: Oncogene – volume: 43 start-page: 2975 year: 1983 end-page: 2984 ident: bib1 article-title: Nonrandom chromosome abnormalities in lymphoma publication-title: Cancer Res – volume: 135 start-page: 1028 year: 2008 end-page: 1038 ident: bib34 article-title: AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations publication-title: Cell – volume: 226 start-page: 1097 year: 1984 end-page: 1099 ident: bib41 article-title: Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation publication-title: Science – volume: 216 start-page: 440 year: 2008 end-page: 450 ident: bib127 article-title: MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation publication-title: J Pathol – volume: 85 start-page: 2528 year: 1995 end-page: 2536 ident: bib57 article-title: Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals publication-title: Blood – volume: 47 start-page: 1086 year: 2008 end-page: 1097 ident: bib80 article-title: Multiple recurrent chromosomal breakpoints in mantle cell lymphoma revealed by a combination of molecular cytogenetic techniques publication-title: Genes Chromosomes Cancer – volume: 23 start-page: 225 year: 2009 end-page: 234 ident: bib95 article-title: Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of today's knowledge publication-title: Leukemia – volume: 113 start-page: 5536 year: 2009 end-page: 5548 ident: bib44 article-title: The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL publication-title: Blood – volume: 460 start-page: 231 year: 2009 end-page: 236 ident: bib53 article-title: Mechanisms promoting translocations in editing and switching peripheral B cells publication-title: Nature – volume: 27 start-page: 5573 year: 2009 end-page: 5579 ident: bib132 article-title: Immuno-fluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: a GELA study publication-title: J Clin Oncol – volume: 83 start-page: 414 year: 2004 end-page: 419 ident: bib123 article-title: Assessment of biological prognostic factors provides clinically relevant information in patients with diffuse large B-cell lymphoma–a Nordic Lymphoma Group study publication-title: Ann Hematol – volume: 86 start-page: 4589 year: 1989 end-page: 4593 ident: bib56 article-title: Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells publication-title: Proc Natl Acad Sci U S A – volume: 92 start-page: 1335 year: 2007 end-page: 1342 ident: bib10 article-title: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement publication-title: Haematologica – volume: 114 start-page: 3533 year: 2009 end-page: 3537 ident: bib128 article-title: MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy publication-title: Blood – volume: 318 start-page: 1373 year: 1988 end-page: 1378 ident: bib48 article-title: Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma publication-title: N Engl J Med – volume: 22 start-page: 2123 year: 2008 end-page: 2127 ident: bib88 article-title: The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia publication-title: Leukemia – volume: 6 start-page: 479 year: 1997 end-page: 490 ident: bib86 article-title: Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions publication-title: Immunity – volume: 86 start-page: 28 year: 1995 end-page: 37 ident: bib65 article-title: BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts publication-title: Blood – volume: 16 start-page: 2333 year: 1998 end-page: 2343 ident: bib93 article-title: Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice publication-title: Oncogene – year: 2008 ident: bib6 article-title: B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma publication-title: WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues – volume: 15 start-page: 1266 year: 2002 end-page: 1272 ident: bib118 article-title: Mantle cell lymphoma with 8q24 chromosomal abnormalities: a report of 5 cases with blastoid features publication-title: Mod Pathol – volume: 49 start-page: 470 year: 2008 end-page: 476 ident: bib104 article-title: C-MYC translocation in t(14;18) positive follicular lymphoma at presentation: An adverse prognostic indicator? publication-title: Leuk Lymphoma – volume: 3 start-page: 189 year: 1991 end-page: 201 ident: bib3 article-title: Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment publication-title: Genes Chromosomes Cancer – volume: 251 start-page: 1211 year: 1991 end-page: 1217 ident: bib22 article-title: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc publication-title: Science – volume: 106 start-page: 11294 year: 2009 end-page: 11299 ident: bib43 article-title: BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma publication-title: Proc Natl Acad Sci U S A – volume: 115 start-page: 975 year: 2010 end-page: 984 ident: bib68 article-title: Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells publication-title: Blood – volume: 94 start-page: 935 year: 2009 end-page: 943 ident: bib11 article-title: Clinicopathological features of lymphoma/leukemia patients carrying both BCL2 and MYC translocations publication-title: Haematologica – volume: 128 start-page: 558 year: 2007 end-page: 564 ident: bib125 article-title: Histopathology and immunohistochemistry in distinguishing Burkitt lymphoma from diffuse large B-cell lymphoma with very high proliferation index and with or without a starry-sky pattern: a comparative study with EBER and FISH publication-title: Am J Clin Pathol – volume: 57 start-page: 79 year: 1989 end-page: 88 ident: bib55 article-title: bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation publication-title: Cell – volume: 29 start-page: 1086 year: 2005 end-page: 1094 ident: bib124 article-title: Clinical, immunophenotypic, and genetic analysis of adult lymphomas with morphologic features of Burkitt lymphoma publication-title: Am J Surg Pathol – volume: 25 start-page: 2770 year: 2007 end-page: 2777 ident: bib121 article-title: Quantitative gene expression deregulation in mantle-cell lymphoma: correlation with clinical and biologic factors publication-title: J Clin Oncol – volume: 23 start-page: 909 year: 2010 end-page: 920 ident: bib116 article-title: Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas publication-title: Mod Pathol – volume: 110 start-page: 2067 year: 2007 end-page: 2074 ident: bib69 article-title: BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms publication-title: Blood – volume: 58 start-page: 5640 year: 1998 end-page: 5645 ident: bib78 article-title: High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies publication-title: Cancer Res – volume: 13 start-page: 3487 year: 1994 end-page: 3495 ident: bib97 article-title: Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice publication-title: EMBO J – volume: 16 start-page: 253 year: 2006 end-page: 264 ident: bib21 article-title: The c-Myc target gene network publication-title: Semin Cancer Biol – volume: 5 start-page: 1225 year: 2006 end-page: 1233 ident: bib16 article-title: Distinguishing primary and secondary translocations in multiple myeloma publication-title: DNA Repair – volume: 205 start-page: 3079 year: 2008 end-page: 3090 ident: bib54 article-title: Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching publication-title: J Exp Med – volume: 348 start-page: 331 year: 1990 end-page: 333 ident: bib62 article-title: Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2 publication-title: Nature – volume: 60 start-page: 991 year: 1990 end-page: 997 ident: bib87 article-title: The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control publication-title: Cell – volume: 349 start-page: 254 year: 1991 end-page: 256 ident: bib63 article-title: Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18) publication-title: Nature – volume: 99 start-page: 3376 year: 2002 end-page: 3382 ident: bib61 article-title: In situ localization of follicular lymphoma: description and analysis by laser capture microdissection publication-title: Blood – volume: 21 start-page: 1532 year: 2007 end-page: 1544 ident: bib89 article-title: A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation publication-title: Leukemia – volume: 13 start-page: 17 year: 1984 end-page: 28 ident: bib2 article-title: Recurrent chromosomal defects are found in most patients with non-Hodgkin's-lymphoma publication-title: Cancer Genet Cytogenet – volume: 149 start-page: 896 year: 2010 end-page: 899 ident: bib26 article-title: MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma publication-title: Br J Haematol – volume: 13 start-page: 199 year: 2000 end-page: 212 ident: bib70 article-title: BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control publication-title: Immunity – volume: 22 start-page: 2226 year: 2008 end-page: 2229 ident: bib108 article-title: Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL) publication-title: Leukemia – volume: 23 start-page: 1190 year: 2009 end-page: 1193 ident: bib83 article-title: t(11;14)-positive clones can persist over a long period of time in the peripheral blood of healthy individuals publication-title: Leukemia – volume: 20 start-page: 64 year: 1997 end-page: 72 ident: bib92 article-title: BCL3 rearrangements and t(14;19) in chronic lymphocytic leukemia and other B-cell malignancies: a molecular and cytogenetic study publication-title: Genes Chromosomes Cancer – volume: 95 start-page: 3520 year: 2000 end-page: 3529 ident: bib51 article-title: Follicular lymphomas' BCL-2/IgH junctions contain templated nucleotide insertions: novel insights into the mechanism of t(14;18) translocation publication-title: Blood – volume: 105 start-page: 13520 year: 2008 end-page: 13525 ident: bib107 article-title: Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways publication-title: Proc Natl Acad Sci U S A – volume: 118 start-page: 431 year: 2004 end-page: 438 ident: bib31 article-title: AID is required for c-myc/IgH chromosome translocations in vivo publication-title: Cell – volume: 84 start-page: 1361 year: 1994 end-page: 1392 ident: bib9 article-title: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group publication-title: Blood – volume: 112 start-page: 1374 year: 2008 end-page: 1381 ident: bib122 article-title: Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials publication-title: Blood – volume: 13 start-page: 2124 year: 1994 end-page: 2130 ident: bib96 article-title: Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene publication-title: EMBO J – volume: 24 start-page: 4135 year: 2006 end-page: 4142 ident: bib133 article-title: Prognostic impact of germinal center-associated proteins and chromosomal breakpoints in poor-risk diffuse large B-cell lymphoma publication-title: J Clin Oncol – year: 2010 ident: bib8 publication-title: Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer – volume: 114 start-page: 2273 year: 2009 end-page: 2279 ident: bib15 article-title: Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival publication-title: Blood – volume: 92 start-page: 6577 year: 1995 end-page: 6581 ident: bib38 article-title: Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men publication-title: Proc Natl Acad Sci U S A – volume: 7 start-page: 123 year: 1988 end-page: 131 ident: bib45 article-title: Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma publication-title: EMBO J – volume: 7 start-page: 445 year: 2005 end-page: 455 ident: bib76 article-title: Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice publication-title: Cancer Cell – volume: 94 start-page: 6658 year: 1997 end-page: 6663 ident: bib25 article-title: c-Myc transactivation of LDH-A: implications for tumor metabolism and growth publication-title: Proc Natl Acad Sci U S A – volume: 435 start-page: 839 year: 2005 end-page: 843 ident: bib28 article-title: c-Myc-regulated microRNAs modulate E2F1 expression publication-title: Nature – volume: 14 start-page: 3011 year: 1997 end-page: 3016 ident: bib39 article-title: Chromosomal translocations deregulating c-myc are associated with normal immune responses publication-title: Oncogene – volume: 276 start-page: 589 year: 1997 end-page: 592 ident: bib67 article-title: Control of inflammation, cytokine expression, and germinal center formation by BCL-6 publication-title: Science – volume: 80 start-page: 758 year: 1992 end-page: 767 ident: bib105 article-title: MYC rearrangements in histologically progressed follicular lymphomas publication-title: Blood – volume: 12 start-page: 280 year: 2007 end-page: 292 ident: bib75 article-title: A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma publication-title: Cancer Cell – volume: 203 start-page: 2425 year: 2006 end-page: 2431 ident: bib60 article-title: Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis publication-title: J Exp Med – volume: 135 start-page: 1130 year: 2008 end-page: 1142 ident: bib50 article-title: Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity publication-title: Cell – volume: 34 start-page: 1686 year: 2010 end-page: 1694 ident: bib18 article-title: IG/MYC rearrangements are the main cytogenetic alteration in plasmablastic lymphomas publication-title: Am J Surg Pathol – volume: 36 start-page: 631 year: 2009 end-page: 641 ident: bib33 article-title: AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations publication-title: Mol Cell – start-page: 32 year: 2008 end-page: 36 ident: bib35 article-title: Structure and consequences of IGH switch breakpoints in Burkitt lymphoma publication-title: J Natl Cancer Inst Monogr – volume: 354 start-page: 2419 year: 2006 end-page: 2430 ident: bib109 article-title: A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling publication-title: N Engl J Med – volume: 43 start-page: 783 year: 2002 end-page: 791 ident: bib79 article-title: Cytogenetic analysis in mantle cell lymphoma: a review of 214 cases publication-title: Leuk Lymphoma – volume: 126 start-page: 45 year: 2001 end-page: 51 ident: bib106 article-title: Chromosomal analyses of 52 cases of follicular lymphoma with t(14;18), including blastic/blastoid variant publication-title: Cancer Genet Cytogenet – volume: 173 start-page: 1158 year: 2004 end-page: 1165 ident: bib72 article-title: Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation publication-title: J Immunol – volume: 85 start-page: 1225 year: 2000 end-page: 1227 ident: bib98 article-title: 8q24 translocations in blastic transformation of mantle cell lymphoma publication-title: Haematologica – volume: 40 start-page: 645 year: 2009 end-page: 652 ident: bib131 article-title: BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: a multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome publication-title: Hum Pathol – volume: 62 start-page: 754 year: 2009 end-page: 756 ident: bib130 article-title: Aberrations of the MYC gene in unselected cases of diffuse large B-cell lymphoma are rare and unpredictable by morphological or immunohistochemical assessment publication-title: J Clin Pathol – volume: 13 start-page: 316 year: 2001 end-page: 324 ident: bib5 article-title: Molecular features of B-cell lymphoma publication-title: Curr Opin Oncol – volume: 100 start-page: 233 year: 2009 end-page: 237 ident: bib117 article-title: Clinical significance of 8q24/c-MYC translocation in diffuse large B-cell lymphoma publication-title: Cancer Sci – volume: 84 start-page: 9257 year: 1987 end-page: 9260 ident: bib90 article-title: Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia publication-title: Proc Natl Acad Sci U S A – volume: 29 start-page: 488 year: 2008 end-page: 498 ident: bib46 article-title: Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway publication-title: Mol Cell – volume: 20 start-page: 5611 year: 2001 end-page: 5622 ident: bib17 article-title: Chromosome translocations in multiple myeloma publication-title: Oncogene – volume: 63 start-page: 1722 year: 2003 end-page: 1723 ident: bib59 article-title: Correspondence re: Welzel et al, Cancer Res 2001, 61(4):1629-1636 publication-title: Cancer Res – volume: 354 start-page: 2431 year: 2006 end-page: 2442 ident: bib110 article-title: Molecular diagnosis of Burkitt's lymphoma publication-title: N Engl J Med – volume: 40 start-page: 43 year: 2008 end-page: 50 ident: bib27 article-title: Widespread microRNA repression by Myc contributes to tumorigenesis publication-title: Nat Genet – volume: 28 start-page: 3360 year: 2010 end-page: 3365 ident: bib114 article-title: Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab publication-title: J Clin Oncol – volume: 49 start-page: 740 year: 2008 end-page: 750 ident: bib119 article-title: Blastic mantle cell lymphoma with a Burkitt translocation publication-title: Leuk Lymphoma – volume: 19 start-page: 25 year: 2006 end-page: 33 ident: bib13 article-title: Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis publication-title: Mod Pathol – volume: 45 start-page: 2143 year: 2004 end-page: 2147 ident: bib99 article-title: Burkitt transformation of mantle cell lymphoma publication-title: Leuk Lymphoma – volume: 74 start-page: 11 issue: 1 year: 2005 ident: 2019111810181455200_B102 article-title: Presence of somatic hypermutation and activation-induced cytidine deaminase in acute lymphoblastic leukemia L2 with t(14;18)(q32;q21). publication-title: Eur J Haematol doi: 10.1111/j.1600-0609.2004.00338.x – volume: 19 start-page: 25 issue: 1 year: 2006 ident: 2019111810181455200_B13 article-title: Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis. publication-title: Mod Pathol doi: 10.1038/modpathol.3800500 – volume: 149 start-page: 484 issue: 4 year: 2010 ident: 2019111810181455200_B30 article-title: Advances in the understanding of MYC-induced lymphomagenesis. publication-title: Br J Haematol doi: 10.1111/j.1365-2141.2010.08159.x – volume: 354 start-page: 2419 issue: 23 year: 2006 ident: 2019111810181455200_B109 article-title: A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. publication-title: N Engl J Med doi: 10.1056/NEJMoa055351 – volume: 20 start-page: 5611 issue: 40 year: 2001 ident: 2019111810181455200_B17 article-title: Chromosome translocations in multiple myeloma. publication-title: Oncogene doi: 10.1038/sj.onc.1204641 – volume: 318 start-page: 1373 issue: 21 year: 1988 ident: 2019111810181455200_B48 article-title: Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma. publication-title: N Engl J Med doi: 10.1056/NEJM198805263182106 – volume: 94 start-page: 6658 issue: 13 year: 1997 ident: 2019111810181455200_B25 article-title: c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.94.13.6658 – volume: 112 start-page: 1374 issue: 4 year: 2008 ident: 2019111810181455200_B122 article-title: Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. publication-title: Blood doi: 10.1182/blood-2008-01-136465 – volume: 115 start-page: 975 issue: 5 year: 2010 ident: 2019111810181455200_B68 article-title: Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. publication-title: Blood doi: 10.1182/blood-2009-06-227017 – volume: 204 start-page: 819 issue: 4 year: 2007 ident: 2019111810181455200_B71 article-title: Repression of BCL-6 is required for the formation of human memory B cells in vitro. publication-title: J Exp Med doi: 10.1084/jem.20062104 – volume: 95 start-page: 3520 issue: 11 year: 2000 ident: 2019111810181455200_B51 article-title: Follicular lymphomas' BCL-2/IgH junctions contain templated nucleotide insertions: novel insights into the mechanism of t(14;18) translocation. publication-title: Blood doi: 10.1182/blood.V95.11.3520 – volume: 92 start-page: 1335 issue: 10 year: 2007 ident: 2019111810181455200_B10 article-title: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement. publication-title: Haematologica doi: 10.3324/haematol.11305 – volume: 229 start-page: 1390 issue: 4720 year: 1985 ident: 2019111810181455200_B49 article-title: The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. publication-title: Science doi: 10.1126/science.3929382 – volume: 86 start-page: 45 issue: 1 year: 1995 ident: 2019111810181455200_B64 article-title: BCL-6 protein is expressed in germinal-center B cells. publication-title: Blood doi: 10.1182/blood.V86.1.45.bloodjournal86145 – volume: 432 start-page: 635 issue: 7017 year: 2004 ident: 2019111810181455200_B73 article-title: The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. publication-title: Nature doi: 10.1038/nature03147 – volume: 2 start-page: 431 issue: 5 year: 1988 ident: 2019111810181455200_B100 article-title: Pre-B-cell leukemia with a t(8; 14) and a t(14; 18) translocation is preceded by follicular lymphoma. publication-title: Oncogene – volume: 6 start-page: 479 issue: 4 year: 1997 ident: 2019111810181455200_B86 article-title: Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions. publication-title: Immunity doi: 10.1016/S1074-7613(00)80291-5 – volume: 90 start-page: 2935 issue: 7 year: 1993 ident: 2019111810181455200_B24 article-title: Opposite regulation of gene transcription and cell proliferation by c-Myc and Max. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.90.7.2935 – volume: 49 start-page: 470 issue: 3 year: 2008 ident: 2019111810181455200_B104 article-title: C-MYC translocation in t(14;18) positive follicular lymphoma at presentation: An adverse prognostic indicator? publication-title: Leuk Lymphoma doi: 10.1080/10428190701836845 – volume: 126 start-page: 45 issue: 1 year: 2001 ident: 2019111810181455200_B106 article-title: Chromosomal analyses of 52 cases of follicular lymphoma with t(14;18), including blastic/blastoid variant. publication-title: Cancer Genet Cytogenet doi: 10.1016/S0165-4608(00)00383-6 – volume: 129 start-page: 157 issue: 1 year: 2008 ident: 2019111810181455200_B101 article-title: Transformation of follicular lymphoma to precursor B-cell lymphoblastic lymphoma with c-myc gene rearrangement as a critical event. publication-title: Am J Clin Pathol doi: 10.1309/NKK3FEX2BE5L7EKB – volume: 460 start-page: 231 issue: 7252 year: 2009 ident: 2019111810181455200_B53 article-title: Mechanisms promoting translocations in editing and switching peripheral B cells. publication-title: Nature doi: 10.1038/nature08159 – volume: 114 start-page: 3533 issue: 17 year: 2009 ident: 2019111810181455200_B128 article-title: MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy. publication-title: Blood doi: 10.1182/blood-2009-05-220095 – volume: 80 start-page: 1512 issue: 5 year: 1987 ident: 2019111810181455200_B42 article-title: Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells. publication-title: J Clin Invest doi: 10.1172/JCI113235 – volume: 20 start-page: 158 issue: 1 year: 2006 ident: 2019111810181455200_B58 article-title: Long-term clonal persistence and evolution of t(14;18)-bearing B cells in healthy individuals. publication-title: Leukemia doi: 10.1038/sj.leu.2404035 – volume: 13 start-page: 2124 issue: 9 year: 1994 ident: 2019111810181455200_B96 article-title: Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. publication-title: EMBO J doi: 10.1002/j.1460-2075.1994.tb06488.x – volume: 7 start-page: 2057 issue: 12 year: 1993 ident: 2019111810181455200_B91 article-title: Molecular characterization of the t(14;19)(q32;q13) translocation in chronic lymphocytic leukemia. publication-title: Leukemia – volume: 95 start-page: 2691 issue: 8 year: 2000 ident: 2019111810181455200_B84 article-title: Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32). publication-title: Blood – volume: 7 start-page: 123 issue: 1 year: 1988 ident: 2019111810181455200_B45 article-title: Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. publication-title: EMBO J doi: 10.1002/j.1460-2075.1988.tb02791.x – volume: 57 start-page: 79 issue: 1 year: 1989 ident: 2019111810181455200_B55 article-title: bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. publication-title: Cell doi: 10.1016/0092-8674(89)90174-8 – volume: 85 start-page: 2528 issue: 9 year: 1995 ident: 2019111810181455200_B57 article-title: Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals. publication-title: Blood doi: 10.1182/blood.V85.9.2528.bloodjournal8592528 – volume: 88 start-page: 1177 issue: 4 year: 1996 ident: 2019111810181455200_B77 article-title: Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization. publication-title: Blood doi: 10.1182/blood.V88.4.1177.bloodjournal8841177 – volume: 8 start-page: 446 issue: 6 year: 2008 ident: 2019111810181455200_B36 article-title: c-Myc: linking transformation and genomic instability. publication-title: Curr Mol Med doi: 10.2174/156652408785747988 – volume: 216 start-page: 440 issue: 4 year: 2008 ident: 2019111810181455200_B127 article-title: MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation. publication-title: J Pathol doi: 10.1002/path.2410 – volume: 92 start-page: 6577 issue: 14 year: 1995 ident: 2019111810181455200_B38 article-title: Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.92.14.6577 – volume: 95 start-page: 253 issue: 2 year: 2010 ident: 2019111810181455200_B113 article-title: Pediatric follicular lymphoma–a clinico-pathological study of a population-based series of patients treated within the Non-Hodgkin's Lymphoma–Berlin-Frankfurt-Munster (NHL-BFM) multicenter trials. publication-title: Haematologica doi: 10.3324/haematol.2009.013177 – volume: 112 start-page: 828 issue: 6 year: 1999 ident: 2019111810181455200_B126 article-title: De novo CD5+ Burkitt lymphoma/leukemia. publication-title: Am J Clin Pathol doi: 10.1093/ajcp/112.6.828 – volume: 43 start-page: 2975 issue: 6 year: 1983 ident: 2019111810181455200_B1 article-title: Nonrandom chromosome abnormalities in lymphoma. publication-title: Cancer Res – volume: 61 start-page: 1629 issue: 4 year: 2001 ident: 2019111810181455200_B82 article-title: Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma. publication-title: Cancer Res – volume: 22 start-page: 2123 issue: 11 year: 2008 ident: 2019111810181455200_B88 article-title: The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia. publication-title: Leukemia doi: 10.1038/leu.2008.102 – volume: 25 start-page: 2770 issue: 19 year: 2007 ident: 2019111810181455200_B121 article-title: Quantitative gene expression deregulation in mantle-cell lymphoma: correlation with clinical and biologic factors. publication-title: J Clin Oncol doi: 10.1200/JCO.2006.08.7999 – volume: 42 start-page: 1181 issue: 6 year: 2001 ident: 2019111810181455200_B52 article-title: Novel insights into the mechanism of t(14;18)(q32;q21) translocation in follicular lymphoma. publication-title: Leuk Lymphoma doi: 10.3109/10428190109097743 – volume: 21 start-page: 515 issue: 3 year: 2007 ident: 2019111810181455200_B40 article-title: Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas. publication-title: Leukemia doi: 10.1038/sj.leu.2404529 – volume: 135 start-page: 1130 issue: 6 year: 2008 ident: 2019111810181455200_B50 article-title: Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. publication-title: Cell doi: 10.1016/j.cell.2008.10.035 – volume: 6 start-page: 1569 issue: 9 year: 1991 ident: 2019111810181455200_B85 article-title: Mouse bcl-3: cDNA structure, mapping and stage-dependent expression in B lymphocytes. publication-title: Oncogene – volume: 110 start-page: 2067 issue: 6 year: 2007 ident: 2019111810181455200_B69 article-title: BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms. publication-title: Blood doi: 10.1182/blood-2007-01-069575 – volume: 84 start-page: 9257 issue: 24 year: 1987 ident: 2019111810181455200_B90 article-title: Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.84.24.9257 – volume: 112 start-page: 2248 issue: 6 year: 2008 ident: 2019111810181455200_B115 article-title: A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic Burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial). publication-title: Blood doi: 10.1182/blood-2008-03-145128 – volume: 86 start-page: 4589 issue: 12 year: 1989 ident: 2019111810181455200_B56 article-title: Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.86.12.4589 – volume: 93 start-page: e54 issue: 7 year: 2008 ident: 2019111810181455200_B19 article-title: Reply to: Comment to: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement. Haematologica. 2007; 92(10):1335-1342. publication-title: Haematologica doi: 10.3324/haematol.13220 – volume: 34 start-page: 327 issue: 3 year: 2010 ident: 2019111810181455200_B14 article-title: B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma. publication-title: Am J Surg Pathol doi: 10.1097/PAS.0b013e3181cd3aeb – volume: 47 start-page: 1086 issue: 12 year: 2008 ident: 2019111810181455200_B80 article-title: Multiple recurrent chromosomal breakpoints in mantle cell lymphoma revealed by a combination of molecular cytogenetic techniques. publication-title: Genes Chromosomes Cancer doi: 10.1002/gcc.20609 – volume: 16 start-page: 161 issue: 2 year: 1997 ident: 2019111810181455200_B66 article-title: The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. publication-title: Nat Genet doi: 10.1038/ng0697-161 – volume: 29 start-page: 488 issue: 4 year: 2008 ident: 2019111810181455200_B46 article-title: Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway. publication-title: Mol Cell doi: 10.1016/j.molcel.2007.12.029 – volume: 204 start-page: 2225 issue: 9 year: 2007 ident: 2019111810181455200_B32 article-title: A role for AID in chromosome translocations between c-myc and the IgH variable region. publication-title: J Exp Med doi: 10.1084/jem.20070884 – volume: 29 start-page: 1086 issue: 8 year: 2005 ident: 2019111810181455200_B124 article-title: Clinical, immunophenotypic, and genetic analysis of adult lymphomas with morphologic features of Burkitt lymphoma. publication-title: Am J Surg Pathol doi: 10.1097/01.pas.0000168176.71405.e5 – volume: 94 start-page: 935 issue: 7 year: 2009 ident: 2019111810181455200_B11 article-title: Clinicopathological features of lymphoma/leukemia patients carrying both BCL2 and MYC translocations. publication-title: Haematologica doi: 10.3324/haematol.2008.005355 – volume: 21 start-page: 1532 issue: 7 year: 2007 ident: 2019111810181455200_B89 article-title: A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation. publication-title: Leukemia doi: 10.1038/sj.leu.2404695 – volume: 3 start-page: 185 issue: 2 year: 2003 ident: 2019111810181455200_B120 article-title: The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. publication-title: Cancer Cell doi: 10.1016/S1535-6108(03)00028-X – volume: 354 start-page: 2431 issue: 23 year: 2006 ident: 2019111810181455200_B110 article-title: Molecular diagnosis of Burkitt's lymphoma. publication-title: N Engl J Med doi: 10.1056/NEJMoa055759 – volume: 99 start-page: 716 issue: 2 year: 2002 ident: 2019111810181455200_B47 article-title: Follicular lymphoma with a novel t(14;18) breakpoint involving the immunoglobulin heavy chain switch mu region indicates an origin from germinal center B cells. publication-title: Blood doi: 10.1182/blood.V99.2.716 – volume: 14 start-page: 3011 issue: 25 year: 1997 ident: 2019111810181455200_B39 article-title: Chromosomal translocations deregulating c-myc are associated with normal immune responses. publication-title: Oncogene doi: 10.1038/sj.onc.1201156 – volume: 205 start-page: 3079 issue: 13 year: 2008 ident: 2019111810181455200_B54 article-title: Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching. publication-title: J Exp Med doi: 10.1084/jem.20082271 – volume: 226 start-page: 1097 issue: 4678 year: 1984 ident: 2019111810181455200_B41 article-title: Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. publication-title: Science doi: 10.1126/science.6093263 – volume: 13 start-page: 316 issue: 5 year: 2001 ident: 2019111810181455200_B5 article-title: Molecular features of B-cell lymphoma. publication-title: Curr Opin Oncol doi: 10.1097/00001622-200109000-00002 – volume: 93 start-page: e53 issue: 7 year: 2008 ident: 2019111810181455200_B20 article-title: Comment to: The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement. Haematologica. 2007; 92(10):1335-1342. publication-title: Haematologica doi: 10.3324/haematol.13190 – volume: 349 start-page: 254 issue: 6306 year: 1991 ident: 2019111810181455200_B63 article-title: Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18). publication-title: Nature doi: 10.1038/349254a0 – volume: 135 start-page: 1028 issue: 6 year: 2008 ident: 2019111810181455200_B34 article-title: AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. publication-title: Cell doi: 10.1016/j.cell.2008.09.062 – volume: 80 start-page: 758 issue: 3 year: 1992 ident: 2019111810181455200_B105 article-title: MYC rearrangements in histologically progressed follicular lymphomas. publication-title: Blood doi: 10.1182/blood.V80.3.758.758 – volume: 84 start-page: 1361 issue: 5 year: 1994 ident: 2019111810181455200_B9 article-title: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. publication-title: Blood doi: 10.1182/blood.V84.5.1361.1361 – volume: 99 start-page: 3376 issue: 9 year: 2002 ident: 2019111810181455200_B61 article-title: In situ localization of follicular lymphoma: description and analysis by laser capture microdissection. publication-title: Blood doi: 10.1182/blood.V99.9.3376 – ident: 2019111810181455200_B8 – volume: 3 start-page: 189 issue: 3 year: 1991 ident: 2019111810181455200_B3 article-title: Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment. publication-title: Genes Chromosomes Cancer doi: 10.1002/gcc.2870030304 – volume: 62 start-page: 754 issue: 8 year: 2009 ident: 2019111810181455200_B130 article-title: Aberrations of the MYC gene in unselected cases of diffuse large B-cell lymphoma are rare and unpredictable by morphological or immunohistochemical assessment. publication-title: J Clin Pathol doi: 10.1136/jcp.2009.065227 – volume-title: WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues year: 2008 ident: 2019111810181455200_B6 article-title: B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. – volume: 15 start-page: 1266 issue: 12 year: 2002 ident: 2019111810181455200_B118 article-title: Mantle cell lymphoma with 8q24 chromosomal abnormalities: a report of 5 cases with blastoid features. publication-title: Mod Pathol doi: 10.1097/01.MP.0000037310.82136.99 – volume: 250 start-page: 1149 issue: 4984 year: 1990 ident: 2019111810181455200_B23 article-title: Sequence-specific DNA binding by the c-Myc protein. publication-title: Science doi: 10.1126/science.2251503 – volume: 169 start-page: 613 issue: 3 year: 1989 ident: 2019111810181455200_B94 article-title: Translocation t(14;18) in B cell lymphomas as a cause for defective immunoglobulin production. publication-title: J Exp Med doi: 10.1084/jem.169.3.613 – volume: 13 start-page: 3487 issue: 15 year: 1994 ident: 2019111810181455200_B97 article-title: Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. publication-title: EMBO J doi: 10.1002/j.1460-2075.1994.tb06655.x – volume: 23 start-page: 1190 issue: 6 year: 2009 ident: 2019111810181455200_B83 article-title: t(11;14)-positive clones can persist over a long period of time in the peripheral blood of healthy individuals. publication-title: Leukemia doi: 10.1038/leu.2009.31 – volume: 16 start-page: 253 issue: 4 year: 2006 ident: 2019111810181455200_B21 article-title: The c-Myc target gene network. publication-title: Semin Cancer Biol doi: 10.1016/j.semcancer.2006.07.014 – volume: 13 start-page: 199 issue: 2 year: 2000 ident: 2019111810181455200_B70 article-title: BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. publication-title: Immunity doi: 10.1016/S1074-7613(00)00020-0 – volume: 23 start-page: 909 issue: 7 year: 2010 ident: 2019111810181455200_B116 article-title: Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas. publication-title: Mod Pathol doi: 10.1038/modpathol.2010.76 – volume: 58 start-page: 5640 issue: 24 year: 1998 ident: 2019111810181455200_B78 article-title: High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies. publication-title: Cancer Res – volume: 20 start-page: 64 issue: 1 year: 1997 ident: 2019111810181455200_B92 article-title: BCL3 rearrangements and t(14;19) in chronic lymphocytic leukemia and other B-cell malignancies: a molecular and cytogenetic study. publication-title: Genes Chromosomes Cancer doi: 10.1002/(SICI)1098-2264(199709)20:1<64::AID-GCC10>3.0.CO;2-F – volume: 27 start-page: 5573 issue: 33 year: 2009 ident: 2019111810181455200_B132 article-title: Immuno-fluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: a GELA study. publication-title: J Clin Oncol doi: 10.1200/JCO.2009.22.7058 – volume: 23 start-page: 225 issue: 2 year: 2009 ident: 2019111810181455200_B95 article-title: Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of today's knowledge. publication-title: Leukemia doi: 10.1038/leu.2008.281 – volume: 348 start-page: 331 issue: 6299 year: 1990 ident: 2019111810181455200_B62 article-title: Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. publication-title: Nature doi: 10.1038/348331a0 – volume: 128 start-page: 558 issue: 4 year: 2007 ident: 2019111810181455200_B125 article-title: Histopathology and immunohistochemistry in distinguishing Burkitt lymphoma from diffuse large B-cell lymphoma with very high proliferation index and with or without a starry-sky pattern: a comparative study with EBER and FISH. publication-title: Am J Clin Pathol doi: 10.1309/EQJR3D3V0CCQGP04 – volume: 13 start-page: 17 issue: 1 year: 1984 ident: 2019111810181455200_B2 article-title: Recurrent chromosomal defects are found in most patients with non-Hodgkin's-lymphoma. publication-title: Cancer Genet Cytogenet doi: 10.1016/0165-4608(84)90084-0 – volume: 14 start-page: 6209 issue: 24 year: 1995 ident: 2019111810181455200_B74 article-title: Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. publication-title: EMBO J doi: 10.1002/j.1460-2075.1995.tb00311.x – volume: 105 start-page: 13520 issue: 36 year: 2008 ident: 2019111810181455200_B107 article-title: Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0804295105 – volume: 173 start-page: 1158 issue: 2 year: 2004 ident: 2019111810181455200_B72 article-title: Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation. publication-title: J Immunol doi: 10.4049/jimmunol.173.2.1158 – volume: 83 start-page: 414 issue: 7 year: 2004 ident: 2019111810181455200_B123 article-title: Assessment of biological prognostic factors provides clinically relevant information in patients with diffuse large B-cell lymphoma–a Nordic Lymphoma Group study. publication-title: Ann Hematol doi: 10.1007/s00277-004-0855-x – volume: 276 start-page: 589 issue: 5312 year: 1997 ident: 2019111810181455200_B67 article-title: Control of inflammation, cytokine expression, and germinal center formation by BCL-6. publication-title: Science doi: 10.1126/science.276.5312.589 – volume: 36 start-page: 631 issue: 4 year: 2009 ident: 2019111810181455200_B33 article-title: AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. publication-title: Mol Cell doi: 10.1016/j.molcel.2009.11.007 – volume: 12 start-page: 280 issue: 3 year: 2007 ident: 2019111810181455200_B75 article-title: A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.08.011 – volume: 100 start-page: 233 issue: 2 year: 2009 ident: 2019111810181455200_B117 article-title: Clinical significance of 8q24/c-MYC translocation in diffuse large B-cell lymphoma. publication-title: Cancer Sci doi: 10.1111/j.1349-7006.2008.01035.x – volume: 85 start-page: 1225 issue: 11 year: 2000 ident: 2019111810181455200_B98 article-title: 8q24 translocations in blastic transformation of mantle cell lymphoma. publication-title: Haematologica – volume: 16 start-page: 2333 issue: 18 year: 1998 ident: 2019111810181455200_B93 article-title: Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. publication-title: Oncogene doi: 10.1038/sj.onc.1201771 – volume: 28 start-page: 3360 issue: 20 year: 2010 ident: 2019111810181455200_B114 article-title: Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab. publication-title: J Clin Oncol doi: 10.1200/JCO.2009.26.3947 – volume: 63 start-page: 1722 issue: 7 year: 2003 ident: 2019111810181455200_B59 article-title: Correspondence re: Welzel et al, Cancer Res 2001, 61(4):1629-1636. publication-title: Cancer Res – volume: 113 start-page: 5536 issue: 22 year: 2009 ident: 2019111810181455200_B44 article-title: The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL. publication-title: Blood doi: 10.1182/blood-2008-12-193037 – volume: 24 start-page: 4135 issue: 25 year: 2006 ident: 2019111810181455200_B133 article-title: Prognostic impact of germinal center-associated proteins and chromosomal breakpoints in poor-risk diffuse large B-cell lymphoma. publication-title: J Clin Oncol doi: 10.1200/JCO.2006.05.5897 – volume: 99 start-page: 4265 issue: 12 year: 2002 ident: 2019111810181455200_B7 article-title: Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation. publication-title: Blood doi: 10.1182/blood.V99.12.4265 – volume: 43 start-page: 783 issue: 4 year: 2002 ident: 2019111810181455200_B79 article-title: Cytogenetic analysis in mantle cell lymphoma: a review of 214 cases. publication-title: Leuk Lymphoma doi: 10.1080/10428190290016890 – volume: 47 start-page: 1523 issue: 8 year: 2006 ident: 2019111810181455200_B103 article-title: Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis. publication-title: Leuk Lymphoma doi: 10.1080/10428190600612909 – volume: 251 start-page: 1211 issue: 4998 year: 1991 ident: 2019111810181455200_B22 article-title: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. publication-title: Science doi: 10.1126/science.2006410 – volume: 93 start-page: 1327 issue: 9 year: 2008 ident: 2019111810181455200_B111 article-title: Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma. publication-title: Haematologica doi: 10.3324/haematol.13071 – volume: 49 start-page: 740 issue: 4 year: 2008 ident: 2019111810181455200_B119 article-title: Blastic mantle cell lymphoma with a Burkitt translocation. publication-title: Leuk Lymphoma doi: 10.1080/10428190701852024 – volume: 17 start-page: 1558 issue: 5 year: 1999 ident: 2019111810181455200_B112 article-title: Small noncleaved, non-Burkitt's (Burkit-Like) lymphoma: cytogenetics predict outcome and reflect clinical presentation. publication-title: J Clin Oncol doi: 10.1200/JCO.1999.17.5.1558 – volume: 86 start-page: 28 issue: 1 year: 1995 ident: 2019111810181455200_B65 article-title: BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts. publication-title: Blood doi: 10.1182/blood.V86.1.28.bloodjournal86128 – volume: 5 start-page: 1225 issue: 9-10 year: 2006 ident: 2019111810181455200_B16 article-title: Distinguishing primary and secondary translocations in multiple myeloma. publication-title: DNA Repair doi: 10.1016/j.dnarep.2006.05.012 – volume: 7 start-page: 251 issue: 3 year: 1996 ident: 2019111810181455200_B81 article-title: Involvement of the CCND1 gene in hairy cell leukemia. publication-title: Ann Oncol doi: 10.1093/oxfordjournals.annonc.a010568 – volume: 53 start-page: 205 issue: 2 year: 2008 ident: 2019111810181455200_B129 article-title: MYC translocation and an increased copy number predict poor prognosis in adult diffuse large B-cell lymphoma (DLBCL), especially in germinal centre-like B cell (GCB) type. publication-title: Histopathology doi: 10.1111/j.1365-2559.2008.03076.x – volume: 22 start-page: 2226 issue: 12 year: 2008 ident: 2019111810181455200_B108 article-title: Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). publication-title: Leukemia doi: 10.1038/leu.2008.230 – volume: 149 start-page: 896 issue: 6 year: 2010 ident: 2019111810181455200_B26 article-title: MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma. publication-title: Br J Haematol doi: 10.1111/j.1365-2141.2010.08111.x – volume: 40 start-page: 43 issue: 1 year: 2008 ident: 2019111810181455200_B27 article-title: Widespread microRNA repression by Myc contributes to tumorigenesis. publication-title: Nat Genet doi: 10.1038/ng.2007.30 – start-page: 32 issue: 39 year: 2008 ident: 2019111810181455200_B35 article-title: Structure and consequences of IGH switch breakpoints in Burkitt lymphoma. publication-title: J Natl Cancer Inst Monogr doi: 10.1093/jncimonographs/lgn020 – volume-title: Cancer Cytogenetics year: 2009 ident: 2019111810181455200_B4 article-title: Mature B- and T-cell neoplasms and Hodgkin lymphomas. – volume: 114 start-page: 2273 issue: 11 year: 2009 ident: 2019111810181455200_B15 article-title: Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival. publication-title: Blood doi: 10.1182/blood-2009-03-212191 – volume: 106 start-page: 11294 issue: 27 year: 2009 ident: 2019111810181455200_B43 article-title: BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0903854106 – volume: 118 start-page: 431 issue: 4 year: 2004 ident: 2019111810181455200_B31 article-title: AID is required for c-myc/IgH chromosome translocations in vivo. publication-title: Cell doi: 10.1016/j.cell.2004.08.006 – volume: 60 start-page: 991 issue: 6 year: 1990 ident: 2019111810181455200_B87 article-title: The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. publication-title: Cell doi: 10.1016/0092-8674(90)90347-H – volume: 23 start-page: 777 issue: 4 year: 2009 ident: 2019111810181455200_B12 article-title: Clinical features and prognosis of de novo diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC translocations. publication-title: Leukemia doi: 10.1038/leu.2008.344 – volume: 7 start-page: 445 issue: 5 year: 2005 ident: 2019111810181455200_B76 article-title: Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice. publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.03.037 – volume: 435 start-page: 839 issue: 7043 year: 2005 ident: 2019111810181455200_B28 article-title: c-Myc-regulated microRNAs modulate E2F1 expression. publication-title: Nature doi: 10.1038/nature03677 – volume: 100 start-page: 2639 issue: 5 year: 2003 ident: 2019111810181455200_B29 article-title: Transcriptional analysis of the B cell germinal center reaction. publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0437996100 – start-page: 37 issue: 39 year: 2008 ident: 2019111810181455200_B37 article-title: Genetic and environmental cofactors of Myc translocations in plasma cell tumor development in mice. publication-title: J Natl Cancer Inst Monogr doi: 10.1093/jncimonographs/lgn015 – volume: 40 start-page: 645 issue: 5 year: 2009 ident: 2019111810181455200_B131 article-title: BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: a multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome. publication-title: Hum Pathol doi: 10.1016/j.humpath.2008.06.032 – volume: 34 start-page: 1686 issue: 11 year: 2010 ident: 2019111810181455200_B18 article-title: IG/MYC rearrangements are the main cytogenetic alteration in plasmablastic lymphomas. publication-title: Am J Surg Pathol doi: 10.1097/PAS.0b013e3181f3e29f – volume: 45 start-page: 2143 issue: 10 year: 2004 ident: 2019111810181455200_B99 article-title: Burkitt transformation of mantle cell lymphoma. publication-title: Leuk Lymphoma doi: 10.1080/10428190410001711479 – volume: 203 start-page: 2425 issue: 11 year: 2006 ident: 2019111810181455200_B60 article-title: Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis. publication-title: J Exp Med doi: 10.1084/jem.20061292 |
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| Snippet | In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double-... |
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| SubjectTerms | Biological and medical sciences Chromosome Breakpoints Genes, myc Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - classification Lymphoma, B-Cell - genetics Medical sciences Prognosis |
| Title | Double-hit B-cell lymphomas |
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