Dietary total antioxidant capacity and its association with sleep, stress, anxiety, and depression score: A cross-sectional study among diabetic women

• Published in: Clinical nutrition ESPEN Vol. 37; pp. 187 - 194
• Main Authors: Daneshzad, Elnaz, Keshavarz, Seyed-Ali, Qorbani, Mostafa, Larijani, Bagher, Azadbakht, Leila
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2020
• Subjects: Antioxidants; anxiety; Anxiety - epidemiology; chronic diseases; Cross-Sectional Studies; Depression; Depression - epidemiology; Diabetes Mellitus, Type 2; Diabetic patients; Diet; Dietary total antioxidant capacity; Female; food frequency questionnaires; food intake; Gastroenterology and Hepatology; Humans; noninsulin-dependent diabetes mellitus; oxygen radical absorbance capacity; patients; Prospective Studies; Sleep; sleep disorders; Women; Women; Dietary total antioxidant capacity; Depression; Sleep; Diabetic patients
• ISSN: 2405-4577; 2405-4577
• DOI: 10.1016/j.clnesp.2020.03.002

Diabetes as a common chronic disease leads to several serious disabilities and complications. Patients with type 2 diabetes are involved with psychological and sleep disorders which diet can be effective in the management of these problems. The present study aimed to investigate the association of Dietary Total Antioxidant Capacity (DTAC) and sleep, stress, anxiety, and depression among diabetic women. This cross-sectional study conducted on 265 women with type 2 diabetes. A validated food frequency questionnaire was filled to evaluate dietary intakes. We calculated DTAC based on amounts of antioxidant in each dietary item using the ferric reducing ability of plasma (FRAP) and oxygen radical absorbance capacity (ORAC) databases. Pittsburgh Sleep Quality Index was used to assess sleep quality. Moreover, 21 items Depression, Anxiety, and Stress Scale was used to assess mental disorders. Subjects in the highest tertile of FRAP and ORAC score compared to those in the lowest tertile of these scores had 94% and 87% lower risk of poor sleep, respectively. The odds of depression were negatively related to the highest tertile of FRAP and ORAC score (OR: 0.21, 95%CI: 0.09–0.50 and OR: 0.21, 95%CI: 0.10–0.48, respectively). Participants with the highest tertile of FRAP compared to those within the lowest tertile of FRAP score had a 59% lower risk of anxiety. The odds of stress were negatively related to the highest tertile of FRAP and ORAC score (OR: 0.10, 95%CI: 0.04–0.23 and OR: 0.13, 95%CI: 0.06–0.29, respectively). There is a significant association between DTAC, sleep status and psychological disorders. However, prospective studies in both genders should be conducted to confirm the actual relationship.