Immunological aspects in chronic lymphocytic leukemia (CLL) development - García-Muñoz, Ricardo; Roldan Galiacho, Verónica; Llorente, Luis (Annals of hematology, 2012)
Keywords: Anergy; Animals; Apoptosis; Autoantigens; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; B-Lymphocytes - physiology; Biomarkers, Tumor - analysis; Biomarkers, Tumor - genetics; Biomarkers, Tumor - physiology; Bone marrow; CD5 antigen; Cell activation; Cell Differentiation - genetics; Cell Differentiation - immunology; Cell survival; Cell Transformation, Neoplastic - genetics; Cell Transformation, Neoplastic - immunology; Chronic lymphatic leukemia; Development; Gene Expression Profiling; Germinal centers; Hematology; Humans; Immune Tolerance - genetics; Immune Tolerance - physiology; Immunoglobulins; Immunological aspects; Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis; Leukemia, Lymphocytic, Chronic, B-Cell - etiology; Leukemia, Lymphocytic, Chronic, B-Cell - immunology; Lymphocytes B; Malignancy; Medicine & Public Health; Models, Biological; Neoplastic Stem Cells - immunology; Neoplastic Stem Cells - physiology; Oncology; Pathogens; Review; Review Article; somatic hypermutation; Somatic Hypermutation, Immunoglobulin - genetics; Somatic Hypermutation, Immunoglobulin - physiology; Surface markers; Self-reactive B cells; Anergy; Clonal deletion; Receptor editing; Receptor revision; Memory B cell checkpoints; CD5+ expression