Characteristics of Adults in the Hepatitis B Research Network in North America Reflect Their Country of Origin and Hepatitis B Virus Genotype

Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from t...

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Published inClinical gastroenterology and hepatology Vol. 13; no. 1; pp. 183 - 192
Main Authors Ghany, Marc G., Perrillo, Robert, Li, Ruosha, Belle, Steven H., Janssen, Harry L.A., Terrault, Norah A., Shuhart, Margaret C., Lau, Daryl T.-Y., Kim, W. Ray, Fried, Michael W., Sterling, Richard K., Di Bisceglie, Adrian M., Han, Steven-Huy B., Ganova-Raeva, Lilia Milkova, Chang, Kyong-Mi, Lok, Anna Suk-Fong, Chung, Raymond T., Roberts, Lewis R., Smith, Coleman I., Lisker-Melman, Mauricio, Wong, David K., Feld, Jordan, Heathcoate, Jenny, Lee, William M., Do, Son, Khalili, Mandana, Fontana, Robert J., Tsai, Naoky, Patel, Keyur, Evon, Donna, Carithers, Robert C., Kowdley, Kris V., Wang, Chia C., Liang, T. Jake, Park, Jang-June, Wahed, Abdus, Kleiner, David, Afdhal, Nezam, Javaid, Asad, Niu, Jianghe, Han, Johanna, Nasser, Imad, Stahler, Alisha C., Stadheim, Linda, Hassan, Mohamed, King, Debra L., La, Danie, Liu, Lucie, Minshall, Stacey, Bass, Sheila, French, Samuel, Peacock, Velma, Ungermann, Ashley, Ayala, Claudia, Olson, Emma, Lau, Ivy, Podolskaya, Veronika, DeVole, Nata, McKenna, Barbara, Oberhelman, Kelly, Kaza, Sravanthi, Rodd, Cassandra, Huddleston, Leslie, Poerzgen, Peter, Darling, Jama M., Barritt, A. Sidney, Marsh, Tiffany, Metheny, Vikki, Cardona, Danielle, Luketic, Velimir A., Smith, Paula G., Mathisen, Terri, Strom, Susan, Mooney, Jody, Cardona-Gonzalez, Lupita, Fryzek, Nancy, Rivera, Elenita, Morris, Nevitt, Haynes-Williams, Vanessa, Valiga, Mary E., Torrey, Keith, Levine, Danielle, Keith, James, Betts, Michael, Montaner, Luis J., Teo, Chong-Gee, Khudyakov, Yury, Punkova, Lili T., Cloonan, Yona, Haller, Tamara, Johnson, Geoffrey, Kelley, Stephanie, Lawlor, Sharon, Lombardero, Manuel, MacGregor, Joan M., Pelesko, Andrew, Stoliker, Donna, Walters, Barbara, Zadorozny, Ella
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.2015
Subjects
Adolescent
Adult
Aged
Aged, 80 and over
ALT
Canada
Chronic Hepatitis B Virus Infection
Emigrants and Immigrants
Female
Gastroenterology and Hepatology
Genotype
HBeAg
Hepatitis B virus - classification
Hepatitis B virus - genetics
Hepatitis B virus - isolation & purification
Hepatitis B, Chronic - virology
Humans
Male
Middle Aged
United States
USA
Young Adult
Canada
United States
USA
Chronic Hepatitis B Virus Infection
DCC
HBeAg
ALT
HBsAg
HCC
HIV
ULN
HBRN
CHB
HBV
NIDDK
chronic hepatitis B
hepatitis B surface antigen
National Institute of Diabetes and Digestive and Kidney Diseases
hepatitis B virus
alanine aminotransferase
hepatitis B e antigen
upper limit of normal
Hepatitis B Research Network
Data Coordinating Center
human immunodeficiency virus
hepatocellular carcinoma
Online AccessGet full text
ISSN1542-3565
1542-7714
1542-7714
DOI10.1016/j.cgh.2014.06.028

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Abstract Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network. The HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America. Half of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range. The HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.
AbstractList Background & Aims Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network. Methods The HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America. Results Half of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range. Conclusions The HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.
Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network. The HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America. Half of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range. The HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.
Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network.BACKGROUND & AIMSChronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network.The HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America.METHODSThe HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America.Half of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range.RESULTSHalf of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range.The HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.CONCLUSIONSThe HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.
Author Niu, Jianghe
Fontana, Robert J.
Rodd, Cassandra
Podolskaya, Veronika
Kelley, Stephanie
Wang, Chia C.
Liang, T. Jake
Han, Johanna
Kowdley, Kris V.
Johnson, Geoffrey
Kleiner, David
Terrault, Norah A.
Fryzek, Nancy
Chung, Raymond T.
Lawlor, Sharon
Barritt, A. Sidney
Metheny, Vikki
Pelesko, Andrew
Ghany, Marc G.
Khalili, Mandana
Ungermann, Ashley
Mathisen, Terri
Punkova, Lili T.
Li, Ruosha
Sterling, Richard K.
Zadorozny, Ella
Khudyakov, Yury
Cloonan, Yona
Haller, Tamara
McKenna, Barbara
Hassan, Mohamed
Di Bisceglie, Adrian M.
Olson, Emma
Liu, Lucie
Huddleston, Leslie
Heathcoate, Jenny
Feld, Jordan
Cardona, Danielle
Peacock, Velma
Ganova-Raeva, Lilia Milkova
Stoliker, Donna
Valiga, Mary E.
Lau, Ivy
Perrillo, Robert
Minshall, Stacey
Wong, David K.
Marsh, Tiffany
Lisker-Melman, Mauricio
Carithers, Robert C.
Wahed, Abdus
DeVole, Nata
Tsai, Naoky
Torrey, Keith
Roberts, Lewis R.
Cardona-Gonzalez, Lupita
Fried, Michael W.
Mooney, Jody
Stahler, Alisha C.
Poerzgen, Peter
Han, Steven-Huy B.
Lau, Daryl T.-Y.
King, Debra L.
Javaid, Asad
Ayala, Claudia
Kim, W. Ray
P
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/25010003$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1055/s-0033-1345716
10.1016/S0016-5085(03)00895-3
10.7326/0003-4819-155-3-201108020-00020
10.1046/j.1365-2893.2002.00304.x
10.1016/S1386-6532(05)00384-7
10.1128/JCM.00813-10
10.1002/hep.24804
10.1371/journal.pone.0027717
10.1016/S0140-6736(12)61728-0
10.2105/AJPH.89.1.14
10.1053/jhep.2001.27834
10.1016/j.jhep.2006.05.013
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Poerzgen, Peter
Rodd, Cassandra
Podolskaya, Veronika
Kelley, Stephanie
Han, Johanna
Javaid, Asad
Ayala, Claudia
Smith, Coleman I
Johnson, Geoffrey
Wang, Chia C
Montaner, Luis J
Patel, Keyur
Betts, Michael
Luketic, Velimir A
Kleiner, David
La, Danie
Park, Jang-June
Tran, Tram T
Lombardero, Manuel
Fryzek, Nancy
Keith, James
Levine, Danielle
King, Debra L
Lawlor, Sharon
Metheny, Vikki
Pelesko, Andrew
Khalili, Mandana
Hofmann, Charlotte
Lee, William M
Kaza, Sravanthi
Ungermann, Ashley
Mathisen, Terri
Walters, Barbara
Bass, Sheila
Haynes-Williams, Vanessa
Fontana, Robert J
Evon, Donna
Darling, Jama M
Stahler, Alisha C
Li, Ruosha
Zadorozny, Ella
Do, Son
Teo, Chong-Gee
Khudyakov, Yury
Cloonan, Yona
Haller, Tamara
Afdhal, Nezam
McKenna, Barbara
Yim, Colina
Hassan, Mohamed
Olson, Emma
Carithers, Robert C
Liu, Lucie
Huddleston, Leslie
Heathcoate, Jenny
Feld, Jordan
Cardona, Danielle
Stadheim, Linda
Peacock, Velma
Morris, Nevitt
Stoliker, Donna
Wong, David K
French, Samuel
Nasser, Imad
Lau, Ivy
Smith, Paula G
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Marsh, Tiffany
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Published by Elsevier Inc.
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CorporateAuthor Hepatitis B Research Network
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Issue 1
Keywords USA
Chronic Hepatitis B Virus Infection
DCC
HBeAg
ALT
HBsAg
HCC
HIV
ULN
HBRN
CHB
HBV
NIDDK
chronic hepatitis B
hepatitis B surface antigen
National Institute of Diabetes and Digestive and Kidney Diseases
hepatitis B virus
alanine aminotransferase
hepatitis B e antigen
upper limit of normal
Hepatitis B Research Network
Data Coordinating Center
human immunodeficiency virus
hepatocellular carcinoma
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References Lozano, Naghavi, Foreman (bib2) 2012; 380
Rotermann, Langlois, Andonov (bib14) 2013; 24
Mitchell, Armstrong, Hu (bib12) 2011; 6
Lavanchy (bib1) 2005; 34
Schwarz, RosenthL, Murray (bib7) 2012; 56
McQuillan, Coleman, Kruszon-Moran (bib4) 1999; 89
Ganova-Raeva, Ramachandran, Honisch (bib6) 2010; 48
Perz, Armstrong, Farrington (bib3) 2006; 45
Wang, Pong, Pollack (bib13) 2011; 155
Chu, Keeffe, Han (bib11) 2003; 125
Kowdley, Wang, Welch (bib5) 2012; 56
Hadziyannis, Vassilopoulos (bib8) 2001; 34
Funk, Rosenberg, Lok (bib9) 2002; 9
Liu, Kao (bib10) 2013; 33
Ganova-Raeva (10.1016/j.cgh.2014.06.028_bib6) 2010; 48
Kowdley (10.1016/j.cgh.2014.06.028_bib5) 2012; 56
Liu (10.1016/j.cgh.2014.06.028_bib10) 2013; 33
Perz (10.1016/j.cgh.2014.06.028_bib3) 2006; 45
Funk (10.1016/j.cgh.2014.06.028_bib9) 2002; 9
Hadziyannis (10.1016/j.cgh.2014.06.028_bib8) 2001; 34
Lavanchy (10.1016/j.cgh.2014.06.028_bib1) 2005; 34
Lozano (10.1016/j.cgh.2014.06.028_bib2) 2012; 380
Chu (10.1016/j.cgh.2014.06.028_bib11) 2003; 125
Schwarz (10.1016/j.cgh.2014.06.028_bib7) 2012; 56
Wang (10.1016/j.cgh.2014.06.028_bib13) 2011; 155
Rotermann (10.1016/j.cgh.2014.06.028_bib14) 2013; 24
McQuillan (10.1016/j.cgh.2014.06.028_bib4) 1999; 89
Mitchell (10.1016/j.cgh.2014.06.028_bib12) 2011; 6
References_xml – volume: 48
  start-page: 4161
  year: 2010
  end-page: 4168
  ident: bib6
  article-title: Robust hepatitis B virus genotyping by mass spectrometry
  publication-title: J Clin Microbiol
– volume: 89
  start-page: 14
  year: 1999
  end-page: 18
  ident: bib4
  article-title: Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994
  publication-title: Am J Public Health
– volume: 380
  start-page: 2095
  year: 2012
  end-page: 2128
  ident: bib2
  article-title: Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
  publication-title: Lancet
– volume: 56
  start-page: 635A
  year: 2012
  ident: bib7
  article-title: Phenotypes of North American children with hepatitis B virus (HBV) infection
  publication-title: Hepatology
– volume: 34
  start-page: 617
  year: 2001
  end-page: 624
  ident: bib8
  article-title: Hepatitis B e antigen-negative chronic hepatitis B
  publication-title: Hepatology
– volume: 6
  start-page: e27717
  year: 2011
  ident: bib12
  article-title: The increasing burden of imported chronic hepatitis B–United States, 1974-2008
  publication-title: PLoS One
– volume: 125
  start-page: 444
  year: 2003
  end-page: 451
  ident: bib11
  article-title: Hepatitis B virus genotypes in the United States: results of a nationwide study
  publication-title: Gastroenterology
– volume: 45
  start-page: 529
  year: 2006
  end-page: 538
  ident: bib3
  article-title: The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
  publication-title: J Hepatol
– volume: 24
  start-page: 3
  year: 2013
  end-page: 13
  ident: bib14
  article-title: Seroprevalence of hepatitis B and C virus infections: results from the 2007 to 2009 and 2009 to 2011 Canadian Health Measures Survey
  publication-title: Health Rep
– volume: 9
  start-page: 52
  year: 2002
  end-page: 61
  ident: bib9
  article-title: World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants
  publication-title: J Viral Hepat
– volume: 155
  start-page: 204
  year: 2011
  end-page: 205
  ident: bib13
  article-title: Hepatitis B virus in the United States
  publication-title: Ann Intern Med
– volume: 56
  start-page: 422
  year: 2012
  end-page: 433
  ident: bib5
  article-title: Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin
  publication-title: Hepatology
– volume: 33
  start-page: 97
  year: 2013
  end-page: 102
  ident: bib10
  article-title: Global perspective on the natural history of chronic hepatitis B: role of hepatitis B virus genotypes A to J
  publication-title: Semin Liver Dis
– volume: 34
  start-page: S1
  year: 2005
  end-page: S3
  ident: bib1
  article-title: Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention
  publication-title: J Clin Virol
– volume: 33
  start-page: 97
  year: 2013
  ident: 10.1016/j.cgh.2014.06.028_bib10
  article-title: Global perspective on the natural history of chronic hepatitis B: role of hepatitis B virus genotypes A to J
  publication-title: Semin Liver Dis
  doi: 10.1055/s-0033-1345716
– volume: 125
  start-page: 444
  year: 2003
  ident: 10.1016/j.cgh.2014.06.028_bib11
  article-title: Hepatitis B virus genotypes in the United States: results of a nationwide study
  publication-title: Gastroenterology
  doi: 10.1016/S0016-5085(03)00895-3
– volume: 24
  start-page: 3
  year: 2013
  ident: 10.1016/j.cgh.2014.06.028_bib14
  article-title: Seroprevalence of hepatitis B and C virus infections: results from the 2007 to 2009 and 2009 to 2011 Canadian Health Measures Survey
  publication-title: Health Rep
– volume: 155
  start-page: 204
  year: 2011
  ident: 10.1016/j.cgh.2014.06.028_bib13
  article-title: Hepatitis B virus in the United States
  publication-title: Ann Intern Med
  doi: 10.7326/0003-4819-155-3-201108020-00020
– volume: 9
  start-page: 52
  year: 2002
  ident: 10.1016/j.cgh.2014.06.028_bib9
  article-title: World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants
  publication-title: J Viral Hepat
  doi: 10.1046/j.1365-2893.2002.00304.x
– volume: 34
  start-page: S1
  issue: Suppl 1
  year: 2005
  ident: 10.1016/j.cgh.2014.06.028_bib1
  article-title: Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention
  publication-title: J Clin Virol
  doi: 10.1016/S1386-6532(05)00384-7
– volume: 48
  start-page: 4161
  year: 2010
  ident: 10.1016/j.cgh.2014.06.028_bib6
  article-title: Robust hepatitis B virus genotyping by mass spectrometry
  publication-title: J Clin Microbiol
  doi: 10.1128/JCM.00813-10
– volume: 56
  start-page: 422
  year: 2012
  ident: 10.1016/j.cgh.2014.06.028_bib5
  article-title: Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin
  publication-title: Hepatology
  doi: 10.1002/hep.24804
– volume: 56
  start-page: 635A
  year: 2012
  ident: 10.1016/j.cgh.2014.06.028_bib7
  article-title: Phenotypes of North American children with hepatitis B virus (HBV) infection
  publication-title: Hepatology
– volume: 6
  start-page: e27717
  year: 2011
  ident: 10.1016/j.cgh.2014.06.028_bib12
  article-title: The increasing burden of imported chronic hepatitis B–United States, 1974-2008
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0027717
– volume: 380
  start-page: 2095
  year: 2012
  ident: 10.1016/j.cgh.2014.06.028_bib2
  article-title: Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
  publication-title: Lancet
  doi: 10.1016/S0140-6736(12)61728-0
– volume: 89
  start-page: 14
  year: 1999
  ident: 10.1016/j.cgh.2014.06.028_bib4
  article-title: Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994
  publication-title: Am J Public Health
  doi: 10.2105/AJPH.89.1.14
– volume: 34
  start-page: 617
  year: 2001
  ident: 10.1016/j.cgh.2014.06.028_bib8
  article-title: Hepatitis B e antigen-negative chronic hepatitis B
  publication-title: Hepatology
  doi: 10.1053/jhep.2001.27834
– volume: 45
  start-page: 529
  year: 2006
  ident: 10.1016/j.cgh.2014.06.028_bib3
  article-title: The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
  publication-title: J Hepatol
  doi: 10.1016/j.jhep.2006.05.013
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Snippet Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United...
Background & Aims Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate...
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SubjectTerms Adolescent
Adult
Aged
Aged, 80 and over
ALT
Canada
Chronic Hepatitis B Virus Infection
Emigrants and Immigrants
Female
Gastroenterology and Hepatology
Genotype
HBeAg
Hepatitis B virus - classification
Hepatitis B virus - genetics
Hepatitis B virus - isolation & purification
Hepatitis B, Chronic - virology
Humans
Male
Middle Aged
United States
USA
Young Adult
Title Characteristics of Adults in the Hepatitis B Research Network in North America Reflect Their Country of Origin and Hepatitis B Virus Genotype
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https://dx.doi.org/10.1016/j.cgh.2014.06.028
https://www.ncbi.nlm.nih.gov/pubmed/25010003
https://www.proquest.com/docview/1637573166
Volume 13
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