The Task Matters: A Comprehensive Review and Proposed Literature Score of the Effects of Chemical and Physical Parameters on Embryo Developmental Competence

To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed original papers using specific keywords and medical subject heading terms. Studies of interest were selected from an initial cohort of 4141 pote...

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Published inLife (Basel, Switzerland) Vol. 13; no. 11; p. 2161
Main Authors Bartolacci, Alessandro, Tondo, Francesca, Alteri, Alessandra, Solano Narduche, Lisett, de Girolamo, Sofia, D’Alessandro, Giulia, Rabellotti, Elisa, Papaleo, Enrico, Pagliardini, Luca
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.11.2023
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ISSN2075-1729
2075-1729
DOI10.3390/life13112161

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Abstract To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed original papers using specific keywords and medical subject heading terms. Studies of interest were selected from an initial cohort of 4141 potentially relevant records retrieved. The most relevant publications were critically evaluated to identify the effect of these parameters on embryo development. Moreover, we generated a literature score (LS) using the following procedure: (i) the number of studies favoring a reference group was expressed as a fraction of all analyzed papers; (ii) the obtained fraction was multiplied by 10 and converted into a decimal number. We identified and discussed six parameters (oxygen, temperature, humidity, oil overlay, light, pH). Moreover, we generated a LS according to five different comparisons (37 °C vs. <37 °C; 5% vs. 20% oxygen; 5–2% vs. 5% oxygen; humidity conditions vs. dry conditions; light exposure vs. reduced/protected light exposure). Only two comparisons (37 °C vs. <37 °C and 5% vs. 20% oxygen) yielded a medium-high LS (8.3 and 7, respectively), suggesting a prevalence of studies in favor of the reference group (37 °C and 5% oxygen). In summary, this review and LS methodology offer semi-quantitative information on studies investigating the effects of chemical and physical parameters on embryo developmental competence.
AbstractList To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed original papers using specific keywords and medical subject heading terms. Studies of interest were selected from an initial cohort of 4141 potentially relevant records retrieved. The most relevant publications were critically evaluated to identify the effect of these parameters on embryo development. Moreover, we generated a literature score (LS) using the following procedure: (i) the number of studies favoring a reference group was expressed as a fraction of all analyzed papers; (ii) the obtained fraction was multiplied by 10 and converted into a decimal number. We identified and discussed six parameters (oxygen, temperature, humidity, oil overlay, light, pH). Moreover, we generated a LS according to five different comparisons (37 °C vs. <37 °C; 5% vs. 20% oxygen; 5-2% vs. 5% oxygen; humidity conditions vs. dry conditions; light exposure vs. reduced/protected light exposure). Only two comparisons (37 °C vs. <37 °C and 5% vs. 20% oxygen) yielded a medium-high LS (8.3 and 7, respectively), suggesting a prevalence of studies in favor of the reference group (37 °C and 5% oxygen). In summary, this review and LS methodology offer semi-quantitative information on studies investigating the effects of chemical and physical parameters on embryo developmental competence.To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed original papers using specific keywords and medical subject heading terms. Studies of interest were selected from an initial cohort of 4141 potentially relevant records retrieved. The most relevant publications were critically evaluated to identify the effect of these parameters on embryo development. Moreover, we generated a literature score (LS) using the following procedure: (i) the number of studies favoring a reference group was expressed as a fraction of all analyzed papers; (ii) the obtained fraction was multiplied by 10 and converted into a decimal number. We identified and discussed six parameters (oxygen, temperature, humidity, oil overlay, light, pH). Moreover, we generated a LS according to five different comparisons (37 °C vs. <37 °C; 5% vs. 20% oxygen; 5-2% vs. 5% oxygen; humidity conditions vs. dry conditions; light exposure vs. reduced/protected light exposure). Only two comparisons (37 °C vs. <37 °C and 5% vs. 20% oxygen) yielded a medium-high LS (8.3 and 7, respectively), suggesting a prevalence of studies in favor of the reference group (37 °C and 5% oxygen). In summary, this review and LS methodology offer semi-quantitative information on studies investigating the effects of chemical and physical parameters on embryo developmental competence.
To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed original papers using specific keywords and medical subject heading terms. Studies of interest were selected from an initial cohort of 4141 potentially relevant records retrieved. The most relevant publications were critically evaluated to identify the effect of these parameters on embryo development. Moreover, we generated a literature score (LS) using the following procedure: (i) the number of studies favoring a reference group was expressed as a fraction of all analyzed papers; (ii) the obtained fraction was multiplied by 10 and converted into a decimal number. We identified and discussed six parameters (oxygen, temperature, humidity, oil overlay, light, pH). Moreover, we generated a LS according to five different comparisons (37 °C vs. <37 °C; 5% vs. 20% oxygen; 5–2% vs. 5% oxygen; humidity conditions vs. dry conditions; light exposure vs. reduced/protected light exposure). Only two comparisons (37 °C vs. <37 °C and 5% vs. 20% oxygen) yielded a medium-high LS (8.3 and 7, respectively), suggesting a prevalence of studies in favor of the reference group (37 °C and 5% oxygen). In summary, this review and LS methodology offer semi-quantitative information on studies investigating the effects of chemical and physical parameters on embryo developmental competence.
Audience Academic
Author Rabellotti, Elisa
Solano Narduche, Lisett
D’Alessandro, Giulia
Pagliardini, Luca
Bartolacci, Alessandro
Tondo, Francesca
Alteri, Alessandra
de Girolamo, Sofia
Papaleo, Enrico
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Cites_doi 10.1016/j.fertnstert.2016.07.1028
10.1002/(SICI)1098-2795(199805)50:1<30::AID-MRD4>3.0.CO;2-Y
10.1038/bjc.2014.166
10.1530/jrf.0.0990673
10.1093/humrep/dey370
10.1016/j.fertnstert.2018.07.1015
10.1016/S0093-691X(01)00509-X
10.1093/humrep/16.11.2374
10.1016/j.fertnstert.2018.07.1012
10.1093/humrep/den368
10.1095/biolreprod64.6.1845
10.1093/humrep/15.4.896
10.1007/s10815-022-02479-z
10.1093/humrep/deaa370
10.1007/s10815-023-02818-8
10.5653/cerm.2020.03552
10.1016/j.fertnstert.2007.03.040
10.1093/humupd/dmv034
10.1007/s10517-014-2515-z
10.1016/j.rbmo.2018.11.020
10.1007/s10815-014-0247-7
10.1016/S0093-691X(00)00456-8
10.1038/s41598-023-31472-4
10.1016/j.fertnstert.2016.01.035
10.1016/S1472-6483(10)60199-X
10.1093/humrep/den432
10.1007/s10815-006-9088-3
10.1016/j.rbmo.2014.01.004
10.1007/s10815-019-01515-9
10.1093/molehr/gan065
10.1016/S0015-0282(16)58097-2
10.1071/RD22125
10.1016/S0015-0282(02)03117-5
10.1016/j.fertnstert.2009.03.077
10.1007/s10815-016-0693-5
10.1093/humrep/deac165
10.1093/humrep/dei006
10.1016/j.fertnstert.2007.01.036
10.1117/1.JBO.19.3.035006
10.1016/j.fertnstert.2008.07.1707
10.1093/humrep/dew016
10.1002/mrd.1080330310
10.1093/humrep/deac107.164
10.1016/j.fertnstert.2004.02.121
10.1016/j.rbmo.2018.03.011
10.1159/000509016
10.1016/j.fertnstert.2008.03.051
10.1016/S0015-0282(00)01800-8
10.1016/S0015-0282(16)57305-1
10.1016/j.fertnstert.2006.05.066
10.1016/j.fertnstert.2017.05.036
10.1002/(SICI)1098-2795(199912)54:4<396::AID-MRD10>3.0.CO;2-6
10.1210/er.2014-1046
10.1038/201316a0
10.1016/j.jri.2019.02.003
10.1016/S0015-0282(16)60377-1
10.1155/2022/9603185
10.1016/j.fertnstert.2018.07.163
10.1093/humrep/13.4.964
10.1093/humrep/14.2.465
10.1016/j.rbmo.2019.02.009
10.1038/s41598-021-01782-6
10.1016/j.fertnstert.2010.10.018
10.1016/j.fertnstert.2018.02.119
10.1530/jrf.0.0850477
10.1016/j.fertnstert.2014.06.009
10.1093/humrep/deab245
10.1093/humrep/13.12.3441
10.1007/BF00318226
10.1016/0093-691X(94)90086-X
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References Barlow (ref_51) 1992; 33
Kovacic (ref_25) 2010; 94
Kaser (ref_7) 2018; 109
ref_10
Bedford (ref_52) 1989; 85
Bontekoe (ref_6) 2012; 11
Roman (ref_29) 2017; 32
Jeon (ref_62) 2022; 34
Phillips (ref_66) 2000; 15
Higdon (ref_35) 2008; 89
Nakayama (ref_55) 1994; 41
Swain (ref_73) 2019; 39
Sakharova (ref_61) 2014; 157
Li (ref_57) 2014; 31
Geraghty (ref_71) 2014; 111
Kea (ref_20) 2007; 87
Bodis (ref_64) 2020; 29
Fischer (ref_50) 1988; 50
Schumacher (ref_49) 1998; 50
Korhonen (ref_59) 2009; 24
Papadopoulou (ref_31) 2022; 37
Chi (ref_43) 2020; 47
Albert (ref_47) 2018; 110
Holmes (ref_13) 2018; 110
Fischer (ref_18) 1993; 99
Fawzy (ref_41) 2018; 36
Wang (ref_37) 2002; 77
Bartolacci (ref_17) 2023; 40
Chen (ref_32) 2023; 13
Daniel (ref_58) 1964; 201
Fujiwara (ref_72) 2007; 24
Fawzy (ref_15) 2017; 108
Dinkins (ref_63) 2001; 55
Squirrell (ref_65) 2001; 64
Lane (ref_67) 1999; 54
Dumoulin (ref_22) 1999; 14
Oh (ref_60) 2007; 88
Kruger (ref_53) 1985; 68
Schumacher (ref_54) 1988; 178
Mestres (ref_48) 2022; 37
Scarica (ref_9) 2022; 39
Brouillet (ref_33) 2021; 11
Mestres (ref_45) 2021; 36
Bedaiwy (ref_5) 2004; 82
ref_30
Yumoto (ref_14) 2019; 36
Yang (ref_8) 2016; 33
Swain (ref_12) 2014; 28
Thouas (ref_76) 2015; 36
Wale (ref_2) 2016; 22
Leese (ref_4) 2008; 14
Edwards (ref_70) 1998; 13
Swain (ref_3) 2016; 105
Dale (ref_69) 1998; 13
Lane (ref_74) 2001; 55
Wang (ref_38) 2001; 16
Zenzes (ref_36) 2001; 75
Baak (ref_42) 2019; 9
Hentemann (ref_68) 2011; 95
Ciray (ref_23) 2009; 91
Kovacic (ref_24) 2008; 17
Swain (ref_46) 2016; 106
Bognar (ref_11) 2019; 132
Valera (ref_16) 2022; 37
Bahat (ref_34) 2005; 20
Hellberg (ref_19) 2009; 91
Janssens (ref_40) 2019; 38
Hong (ref_39) 2014; 102
Dumoulin (ref_21) 1995; 63
ref_1
Guo (ref_26) 2014; 15
Meintjes (ref_27) 2009; 24
Schumacher (ref_56) 1991; 183
Swain (ref_44) 2018; 110
Gardner (ref_75) 1996; 65
Janssens (ref_28) 2019; 34
References_xml – volume: 183
  start-page: 559
  year: 1991
  ident: ref_56
  article-title: Effects of visible light and room temperature on the ultrastructure of preimplantation rabbit embryos: A time course study
  publication-title: Anat. Embryol.
– volume: 106
  start-page: 362
  year: 2016
  ident: ref_46
  article-title: Media osmolality changes over 7 days following culture in a non-humidified benchtop incubator
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2016.07.1028
– volume: 50
  start-page: 30
  year: 1998
  ident: ref_49
  article-title: DNA ploidy abnormalities in rabbit preimplantation embryos are not increased by conditions associated with in vitro culture
  publication-title: Mol. Reprod. Dev.
  doi: 10.1002/(SICI)1098-2795(199805)50:1<30::AID-MRD4>3.0.CO;2-Y
– volume: 111
  start-page: 1021
  year: 2014
  ident: ref_71
  article-title: Guidelines for the use of cell lines in biomedical research
  publication-title: Br. J. Cancer
  doi: 10.1038/bjc.2014.166
– volume: 9
  start-page: CD012192
  year: 2019
  ident: ref_42
  article-title: Temperature of embryo culture for assisted reproduction
  publication-title: Cochrane Database Syst. Rev.
– volume: 99
  start-page: 673
  year: 1993
  ident: ref_18
  article-title: Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits
  publication-title: J. Reprod. Fertil.
  doi: 10.1530/jrf.0.0990673
– volume: 34
  start-page: 228
  year: 2019
  ident: ref_28
  article-title: Influence of ultra-low oxygen (2%) tension on in-vitro human embryo development
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/dey370
– volume: 110
  start-page: e363
  year: 2018
  ident: ref_44
  article-title: Media evaporation in a dry culture incubator; effect of dish, drop size and oil on media osmolality
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2018.07.1015
– volume: 55
  start-page: 1639
  year: 2001
  ident: ref_63
  article-title: Photosensitive chemical and laser light treatments decrease epizootic hemorrhagic disease virus associated with in vitro produced bovine embryos
  publication-title: Theriogenology
  doi: 10.1016/S0093-691X(01)00509-X
– volume: 16
  start-page: 2374
  year: 2001
  ident: ref_38
  article-title: Limited recovery of meiotic spindles in living human oocytes after cooling-rewarming observed using polarized light microscopy
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/16.11.2374
– volume: 110
  start-page: e362
  year: 2018
  ident: ref_47
  article-title: Humid vs. dry embryo culture conditions on embryo development: A continuous embryo monitoring assessment
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2018.07.1012
– volume: 24
  start-page: 300
  year: 2009
  ident: ref_27
  article-title: A controlled randomized trial evaluating the effect of lowered incubator oxygen tension on live births in a predominantly blastocyst transfer program
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/den368
– volume: 64
  start-page: 1845
  year: 2001
  ident: ref_65
  article-title: Altering intracellular pH disrupts development and cellular organization in preimplantation hamster embryos
  publication-title: Biol. Reprod.
  doi: 10.1095/biolreprod64.6.1845
– volume: 15
  start-page: 896
  year: 2000
  ident: ref_66
  article-title: Intracellular pH regulation in human preimplantation embryos
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/15.4.896
– volume: 39
  start-page: 883
  year: 2022
  ident: ref_9
  article-title: Use of mineral oil in IVF culture systems: Physico-chemical aspects, management, and safety
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-022-02479-z
– volume: 36
  start-page: 605
  year: 2021
  ident: ref_45
  article-title: Factors of the human embryo culture system that may affect media evaporation and osmolality
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/deaa370
– volume: 68
  start-page: 743
  year: 1985
  ident: ref_53
  article-title: The effect on cleavage of two-cell mouse embryos after a delay in embryo retrieval in a human in vitro fertilization programme
  publication-title: S. Afr. Med. J.
– volume: 40
  start-page: 1429
  year: 2023
  ident: ref_17
  article-title: Humidified atmosphere in a time-lapse embryo culture system does not improve ongoing pregnancy rate: A retrospective propensity score model study derived from 496 first ICSI cycles
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-023-02818-8
– volume: 47
  start-page: 284
  year: 2020
  ident: ref_43
  article-title: Effect of evaporation-induced osmotic changes in culture media in a dry-type incubator on clinical outcomes in in vitro fertilization-embryo transfer cycles
  publication-title: Clin. Exp. Reprod. Med.
  doi: 10.5653/cerm.2020.03552
– volume: 89
  start-page: 703
  year: 2008
  ident: ref_35
  article-title: Incubator management in an assisted reproductive technology laboratory
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2007.03.040
– volume: 22
  start-page: 2
  year: 2016
  ident: ref_2
  article-title: The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction
  publication-title: Hum. Reprod. Update
  doi: 10.1093/humupd/dmv034
– volume: 157
  start-page: 162
  year: 2014
  ident: ref_61
  article-title: Analysis of the effects of blue light on morphofunctional status of in vitro cultured blastocysts from mice carrying gene of enhanced green fluorescent protein (EGFP)
  publication-title: Bull. Exp. Biol. Med.
  doi: 10.1007/s10517-014-2515-z
– volume: 38
  start-page: 508
  year: 2019
  ident: ref_40
  article-title: The effect of different temperature conditions on human embryosin vitro: Two sibling studies
  publication-title: Reprod. Biomed. Online
  doi: 10.1016/j.rbmo.2018.11.020
– volume: 31
  start-page: 795
  year: 2014
  ident: ref_57
  article-title: Effect of red light on the development and quality of mammalian embryos
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-014-0247-7
– volume: 55
  start-page: 225
  year: 2001
  ident: ref_74
  article-title: Mechanisms for managing cellular and homeostatic stress in vitro
  publication-title: Theriogenology
  doi: 10.1016/S0093-691X(00)00456-8
– volume: 13
  start-page: 4330
  year: 2023
  ident: ref_32
  article-title: Biphasic oxygen tension promotes the formation of transferable blastocysts in patients without euploid embryos in previous monophasic oxygen cycles
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-023-31472-4
– volume: 105
  start-page: 571
  year: 2016
  ident: ref_3
  article-title: Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2016.01.035
– volume: 17
  start-page: 229
  year: 2008
  ident: ref_24
  article-title: Influence of atmospheric versus reduced oxygen concentration on development of human blastocysts in vitro: A prospective study on sibling oocytes
  publication-title: Reprod. Biomed. Online
  doi: 10.1016/S1472-6483(10)60199-X
– volume: 24
  start-page: 308
  year: 2009
  ident: ref_59
  article-title: Viability of bovine embryos following exposure to the green filtered or wider bandwidth light during in vitro embryo production
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/den432
– volume: 24
  start-page: 5
  year: 2007
  ident: ref_72
  article-title: Effect of micro-environment maintenance on embryo culture after in-vitro fertilization: Comparison of top-load mini incubator and conventional front-load incubator
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-006-9088-3
– volume: 28
  start-page: 535
  year: 2014
  ident: ref_12
  article-title: Decisions for the IVF laboratory: Comparative analysis of embryo culture incubators
  publication-title: Reprod. Biomed. Online
  doi: 10.1016/j.rbmo.2014.01.004
– volume: 32
  start-page: i26
  year: 2017
  ident: ref_29
  article-title: Ultra-low (2%) oxygen tension significantly improves human blastocyst development and quality
  publication-title: Hum. Reprod.
– volume: 36
  start-page: 1571
  year: 2019
  ident: ref_14
  article-title: Unstable osmolality of microdrops cultured in non-humidified incubators
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-019-01515-9
– volume: 14
  start-page: 667
  year: 2008
  ident: ref_4
  article-title: Metabolism of the viable mammalian embryo: Quietness revisited
  publication-title: Mol. Hum. Reprod.
  doi: 10.1093/molehr/gan065
– volume: 65
  start-page: 349
  year: 1996
  ident: ref_75
  article-title: Environment of the preimplantation human embryo in vivo: Metabolite analysis of oviduct and uterine fluids and metabolism of cumulus cells
  publication-title: Fertil. Steril.
  doi: 10.1016/S0015-0282(16)58097-2
– volume: 34
  start-page: 1052
  year: 2022
  ident: ref_62
  article-title: Effects of light wavelength exposure during in vitro blastocyst production on preimplantation development of mouse embryos
  publication-title: Reprod. Fertil. Dev.
  doi: 10.1071/RD22125
– volume: 77
  start-page: 1274
  year: 2002
  ident: ref_37
  article-title: Rigorous thermal control during intracytoplasmic sperm injection stabilizes the meiotic spindle and improves fertilization and pregnancy rates
  publication-title: Fertil. Steril.
  doi: 10.1016/S0015-0282(02)03117-5
– volume: 94
  start-page: 511
  year: 2010
  ident: ref_25
  article-title: A prospective, randomized trial on the effect of atmospheric versus reduced oxygen concentration on the outcome of intracytoplasmic sperm injection cycles
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2009.03.077
– volume: 11
  start-page: CD008950
  year: 2012
  ident: ref_6
  article-title: Low oxygen concentrations for embryo culture in assisted reproductive technologies
  publication-title: Cochrane Database Syst. Rev.
– volume: 33
  start-page: 919
  year: 2016
  ident: ref_8
  article-title: Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos
  publication-title: J. Assist. Reprod. Genet.
  doi: 10.1007/s10815-016-0693-5
– volume: 37
  start-page: 1980
  year: 2022
  ident: ref_16
  article-title: A propensity score-based, comparative study assessing humid and dry time-lapse incubation, with single-step medium, on embryo development and clinical outcomes
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/deac165
– volume: 20
  start-page: 2118
  year: 2005
  ident: ref_34
  article-title: Periovulatory increase in temperature difference within the rabbit oviduct
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/dei006
– volume: 88
  start-page: 1150
  year: 2007
  ident: ref_60
  article-title: Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2007.01.036
– ident: ref_10
  doi: 10.1117/1.JBO.19.3.035006
– volume: 91
  start-page: 1459
  year: 2009
  ident: ref_23
  article-title: In vitro culture under physiologic oxygen concentration improves blastocyst yield and quality: A prospective randomized survey on sibling oocytes
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2008.07.1707
– ident: ref_1
  doi: 10.1093/humrep/dew016
– volume: 33
  start-page: 297
  year: 1992
  ident: ref_51
  article-title: In vitro fertilization, development, and implantation after exposure of mature mouse oocytes to visible light
  publication-title: Mol. Reprod. Dev.
  doi: 10.1002/mrd.1080330310
– volume: 37
  start-page: 270
  year: 2022
  ident: ref_31
  article-title: Low 5% vs. ultra-low 3% O2 concentration on embryo culture: Is there any difference in quality and ploidy?
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/deac107.164
– volume: 82
  start-page: 593
  year: 2004
  ident: ref_5
  article-title: Differential growth of human embryos in vitro: Role of reactive oxygen species
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2004.02.121
– volume: 36
  start-page: 620
  year: 2018
  ident: ref_41
  article-title: Comparing 36.5 °C with 37 °C for human embryo culture: A prospective randomized controlled trial
  publication-title: Reprod. Biomed. Online
  doi: 10.1016/j.rbmo.2018.03.011
– volume: 29
  start-page: 558
  year: 2020
  ident: ref_64
  article-title: How to reduce the potential harmful effects of light on blastocyst development during IVF
  publication-title: Med. Princ. Pract.
  doi: 10.1159/000509016
– volume: 91
  start-page: 2461
  year: 2009
  ident: ref_19
  article-title: Low-oxygen compared with high-oxygen atmosphere in blastocyst culture, a prospective randomized study
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2008.03.051
– volume: 75
  start-page: 769
  year: 2001
  ident: ref_36
  article-title: Effects of chilling to 0 degrees C on the morphology of meiotic spindles in human metaphase II oocytes
  publication-title: Fertil. Steril.
  doi: 10.1016/S0015-0282(00)01800-8
– volume: 63
  start-page: 115
  year: 1995
  ident: ref_21
  article-title: Effect of oxygen concentration on in vitro fertilization and embryo culture in the human and the mouse
  publication-title: Fertil. Steril.
  doi: 10.1016/S0015-0282(16)57305-1
– volume: 87
  start-page: 213
  year: 2007
  ident: ref_20
  article-title: Effect of reduced oxygen concentrations on the outcome of in vitro fertilization
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2006.05.066
– volume: 108
  start-page: 277
  year: 2017
  ident: ref_15
  article-title: Humid versus dry incubator: A prospective, randomized, controlled trial
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2017.05.036
– volume: 54
  start-page: 396
  year: 1999
  ident: ref_67
  article-title: Regulation of intracellular pH in bovine oocytes and cleavage stage embryos
  publication-title: Mol. Reprod. Dev.
  doi: 10.1002/(SICI)1098-2795(199912)54:4<396::AID-MRD10>3.0.CO;2-6
– volume: 36
  start-page: 92
  year: 2015
  ident: ref_76
  article-title: Soluble ligands and their receptors in human embryo development and implantation
  publication-title: Endocr. Rev.
  doi: 10.1210/er.2014-1046
– volume: 201
  start-page: 316
  year: 1964
  ident: ref_58
  article-title: Clevage of mammalian ova inhibited by visible light
  publication-title: Nature
  doi: 10.1038/201316a0
– volume: 132
  start-page: 21
  year: 2019
  ident: ref_11
  article-title: The effect of light exposure on the cleavage rate and implantation capacity of preimplantation murine embryos
  publication-title: J. Reprod. Immunol.
  doi: 10.1016/j.jri.2019.02.003
– volume: 50
  start-page: 938
  year: 1988
  ident: ref_50
  article-title: Potential risk of light and room temperature exposure to preimplantation embryos
  publication-title: Fertil. Steril.
  doi: 10.1016/S0015-0282(16)60377-1
– ident: ref_30
  doi: 10.1155/2022/9603185
– volume: 110
  start-page: 52
  year: 2018
  ident: ref_13
  article-title: Humidification of a dry benchtop IVF incubator: Impact on culture media parameters
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2018.07.163
– volume: 13
  start-page: 964
  year: 1998
  ident: ref_69
  article-title: Intracellular pH regulation in the human oocyte
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/13.4.964
– volume: 14
  start-page: 465
  year: 1999
  ident: ref_22
  article-title: Effect of oxygen concentration on human in-vitro fertilization and embryo culture
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/14.2.465
– volume: 39
  start-page: 19
  year: 2019
  ident: ref_73
  article-title: Controversies in ART: Considerations and risks for uninterrupted embryo culture
  publication-title: Reprod. Biomed. Online
  doi: 10.1016/j.rbmo.2019.02.009
– volume: 11
  start-page: 22461
  year: 2021
  ident: ref_33
  article-title: Biphasic (5–2%) oxygen concentration strategy significantly improves the usable blastocyst and cumulative live birth rates in in vitro fertilization
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-021-01782-6
– volume: 95
  start-page: 1291
  year: 2011
  ident: ref_68
  article-title: Differential pH in embryo culture
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2010.10.018
– volume: 15
  start-page: 6191
  year: 2014
  ident: ref_26
  article-title: Two different concentrations of oxygen for culturing precompaction stage embryos on human embryo development competence: A prospective randomized sibling-oocyte study
  publication-title: Int. J. Clin. Exp. Pathol.
– volume: 109
  start-page: 1030
  year: 2018
  ident: ref_7
  article-title: Randomized controlled trial of low (5%) versus ultralow (2%) oxygen for extended culture using bipronucleate and tripronucleate human preimplantation embryos
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2018.02.119
– volume: 85
  start-page: 477
  year: 1989
  ident: ref_52
  article-title: Light exposure of oocytes and pregnancy rates after their transfer in the rabbit
  publication-title: J. Reprod. Fertil.
  doi: 10.1530/jrf.0.0850477
– volume: 102
  start-page: 767
  year: 2014
  ident: ref_39
  article-title: Examining the temperature of embryo culture in in vitro fertilization: A randomized controlled trial comparing traditional core temperature (37 °C) to a more physiologic, cooler temperature (36 °C)
  publication-title: Fertil. Steril.
  doi: 10.1016/j.fertnstert.2014.06.009
– volume: 37
  start-page: 212
  year: 2022
  ident: ref_48
  article-title: Characterization and comparison of commercial oils used for human embryo culture
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/deab245
– volume: 13
  start-page: 3441
  year: 1998
  ident: ref_70
  article-title: Intracellular pH of the mouse preimplantation embryo: Amino acids act as buffers of intracellular pH
  publication-title: Hum. Reprod.
  doi: 10.1093/humrep/13.12.3441
– volume: 178
  start-page: 229
  year: 1988
  ident: ref_54
  article-title: Ultrastructure of preimplantation rabbit embryos exposed to visible light and room temperature
  publication-title: Anat. Embryol.
  doi: 10.1007/BF00318226
– volume: 41
  start-page: 499
  year: 1994
  ident: ref_55
  article-title: Effects of visible light and other environmental factors on the production of oxygen radicals by hamster embryos
  publication-title: Theriogenology
  doi: 10.1016/0093-691X(94)90086-X
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Snippet To explore the effects of chemical and physical parameters on embryo developmental competence, we conducted a systematic search on PubMed for peer-reviewed...
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SubjectTerms Biochemistry
Cell culture
Clinical outcomes
Embryology, Experimental
Embryonic development
Embryos
Fertilization in vitro
Humidity
In vitro fertilization
Light
Literature reviews
Metabolism
Methods
oil overlay
Oxygen
Parameter identification
Physical properties
Pregnancy
temperature
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Title The Task Matters: A Comprehensive Review and Proposed Literature Score of the Effects of Chemical and Physical Parameters on Embryo Developmental Competence
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