Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease

Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional dopaminergic systems, including Parkinson’s disease, attention deficit hyperactivity disorder, and sub...

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Published inPharmacological reviews Vol. 67; no. 4; pp. 1005 - 1024
Main Authors German, Christopher L., Baladi, Michelle G., McFadden, Lisa M., Hanson, Glen R., Fleckenstein, Annette E.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2015
The American Society for Pharmacology and Experimental Therapeutics
Subjects
Adrenergic Uptake Inhibitors - pharmacology
Animals
Central Nervous System Diseases - physiopathology
Dopamine - metabolism
Dopamine Agents - pharmacology
Dopamine Plasma Membrane Transport Proteins - pharmacology
Dopamine Plasma Membrane Transport Proteins - physiology
Glycosylation
Humans
Phosphorylation - physiology
Review
Signal Transduction
Synaptic Transmission
Vesicular Monoamine Transport Proteins - classification
Vesicular Monoamine Transport Proteins - pharmacology
Vesicular Monoamine Transport Proteins - physiology
MPD
AADC
VMAT
PD128907
PAL-1045
PKA
GZ-793A
METH
CNS
PKC
PACAP38
RTI55
TBZ
WIN35428
PD
TH
DAT
l-DOPA
PICK1
AMPH
JHW007
JHW013
DA
Online AccessGet full text
ISSN0031-6997
1521-0081
1521-0081
DOI10.1124/pr.114.010397

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Abstract Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional dopaminergic systems, including Parkinson’s disease, attention deficit hyperactivity disorder, and substance abuse. Drugs that modify the DA system are clinically effective in treating symptoms of these diseases or are involved in their manifestation, implicating DA in their etiology. DA signaling and distribution are primarily modulated by the DA transporter (DAT) and by vesicular monoamine transporter (VMAT)-2, which transport DA into presynaptic terminals and synaptic vesicles, respectively. These transporters are regulated by complex processes such as phosphorylation, protein–protein interactions, and changes in intracellular localization. This review provides an overview of 1) the current understanding of DAT and VMAT2 neurobiology, including discussion of studies ranging from those conducted in vitro to those involving human subjects; 2) the role of these transporters in disease and how these transporters are affected by disease; and 3) and how selected drugs alter the function and expression of these transporters. Understanding the regulatory processes and the pathologic consequences of DAT and VMAT2 dysfunction underlies the evolution of therapeutic development for the treatment of DA-related disorders.
AbstractList Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional dopaminergic systems, including Parkinson’s disease, attention deficit hyperactivity disorder, and substance abuse. Drugs that modify the DA system are clinically effective in treating symptoms of these diseases or are involved in their manifestation, implicating DA in their etiology. DA signaling and distribution are primarily modulated by the DA transporter (DAT) and by vesicular monoamine transporter (VMAT)-2, which transport DA into presynaptic terminals and synaptic vesicles, respectively. These transporters are regulated by complex processes such as phosphorylation, protein–protein interactions, and changes in intracellular localization. This review provides an overview of 1) the current understanding of DAT and VMAT2 neurobiology, including discussion of studies ranging from those conducted in vitro to those involving human subjects; 2) the role of these transporters in disease and how these transporters are affected by disease; and 3) and how selected drugs alter the function and expression of these transporters. Understanding the regulatory processes and the pathologic consequences of DAT and VMAT2 dysfunction underlies the evolution of therapeutic development for the treatment of DA-related disorders.
Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional dopaminergic systems, including Parkinson's disease, attention deficit hyperactivity disorder, and substance abuse. Drugs that modify the DA system are clinically effective in treating symptoms of these diseases or are involved in their manifestation, implicating DA in their etiology. DA signaling and distribution are primarily modulated by the DA transporter (DAT) and by vesicular monoamine transporter (VMAT)-2, which transport DA into presynaptic terminals and synaptic vesicles, respectively. These transporters are regulated by complex processes such as phosphorylation, protein-protein interactions, and changes in intracellular localization. This review provides an overview of 1) the current understanding of DAT and VMAT2 neurobiology, including discussion of studies ranging from those conducted in vitro to those involving human subjects; 2) the role of these transporters in disease and how these transporters are affected by disease; and 3) and how selected drugs alter the function and expression of these transporters. Understanding the regulatory processes and the pathologic consequences of DAT and VMAT2 dysfunction underlies the evolution of therapeutic development for the treatment of DA-related disorders.Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional dopaminergic systems, including Parkinson's disease, attention deficit hyperactivity disorder, and substance abuse. Drugs that modify the DA system are clinically effective in treating symptoms of these diseases or are involved in their manifestation, implicating DA in their etiology. DA signaling and distribution are primarily modulated by the DA transporter (DAT) and by vesicular monoamine transporter (VMAT)-2, which transport DA into presynaptic terminals and synaptic vesicles, respectively. These transporters are regulated by complex processes such as phosphorylation, protein-protein interactions, and changes in intracellular localization. This review provides an overview of 1) the current understanding of DAT and VMAT2 neurobiology, including discussion of studies ranging from those conducted in vitro to those involving human subjects; 2) the role of these transporters in disease and how these transporters are affected by disease; and 3) and how selected drugs alter the function and expression of these transporters. Understanding the regulatory processes and the pathologic consequences of DAT and VMAT2 dysfunction underlies the evolution of therapeutic development for the treatment of DA-related disorders.
Author German, Christopher L.
Baladi, Michelle G.
Hanson, Glen R.
McFadden, Lisa M.
Fleckenstein, Annette E.
Author_xml – sequence: 1
  givenname: Christopher L.
  surname: German
  fullname: German, Christopher L.
– sequence: 2
  givenname: Michelle G.
  surname: Baladi
  fullname: Baladi, Michelle G.
– sequence: 3
  givenname: Lisa M.
  surname: McFadden
  fullname: McFadden, Lisa M.
– sequence: 4
  givenname: Glen R.
  surname: Hanson
  fullname: Hanson, Glen R.
– sequence: 5
  givenname: Annette E.
  surname: Fleckenstein
  fullname: Fleckenstein, Annette E.
  email: fleckenstein@hsc.utah.edu
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26408528$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1002/syn.1089
10.1016/j.biopsych.2005.09.018
10.1016/j.tips.2013.07.005
10.1074/jbc.M112.367706
10.1016/S0304-3940(00)01040-5
10.1016/0024-3205(65)90312-7
10.1176/ajp.2007.164.1.160
10.1523/JNEUROSCI.0387-04.2004
10.1038/srep01447
10.1176/appi.ajp.158.3.377
10.1016/0005-2736(94)90051-5
10.1016/S0169-328X(97)00082-X
10.1038/366344a0
10.1016/S0026-895X(25)08925-4
10.1074/jbc.M301845200
10.1002/ana.410400312
10.1371/journal.pone.0016350
10.1523/JNEUROSCI.4559-08.2009
10.1016/0006-2952(82)90332-X
10.1002/(SICI)1098-2396(199706)26:2<194::AID-SYN10>3.0.CO;2-Y
10.1126/science.1948035
10.1016/0006-8993(90)90889-J
10.1016/S0021-9258(17)37272-1
10.1016/S0014-2999(99)00588-9
10.1124/jpet.302.2.497
10.1016/S0014-2999(02)01985-4
10.1016/S0014-2999(99)00487-2
10.1016/S0022-3565(25)13104-2
10.1016/j.neuroimage.2006.10.014
10.1016/S0197-4580(02)00065-9
10.2165/11534430-000000000-00000
10.1176/appi.ajp.157.10.1619
10.1097/NMD.0b013e31817d0153
10.1016/B978-0-12-420118-7.00004-4
10.1146/annurev.pharmtox.47.120505.105140
10.1073/pnas.89.24.11988
10.2147/PRBM.S47013
10.1016/S0022-3565(24)36858-2
10.1016/S0022-3565(24)29485-4
10.1016/j.drugalcdep.2014.12.005
10.1016/j.drugalcdep.2014.10.027
10.1074/jbc.M311972200
10.1074/jbc.M109.054510
10.1016/j.mam.2012.07.002
10.1074/jbc.M011785200
10.1159/000054345
10.1007/s12031-007-0037-0
10.1016/j.neuint.2013.12.003
10.1124/jpet.111.188946
10.1002/ajmg.b.30142
10.1111/add.12608
10.1016/j.neuint.2014.01.002
10.1111/j.1471-4159.2012.07875.x
10.1523/JNEUROSCI.5386-08.2009
10.1074/jbc.M112.441295
10.1046/j.1471-4159.1999.0732406.x
10.1124/jpet.113.205310
10.1111/j.1471-4159.2010.06922.x
10.1053/scnp.2003.50012
10.1073/pnas.90.19.8861
10.1006/bbrc.2002.6384
10.1523/JNEUROSCI.17-11-04037.1997
10.1074/jbc.M501969200
10.1016/0166-4328(93)90109-4
10.1038/nn1478
10.1016/j.jns.2014.01.015
10.1096/fasebj.4.10.2197154
10.1046/j.1471-4159.2000.0742221.x
10.1111/j.1471-4159.1965.tb10247.x
10.1016/B978-0-12-420118-7.00002-0
10.1016/j.neuropharm.2011.02.028
10.4088/JCP.v65n0507
10.1002/ana.22284
10.1074/jbc.M110.150565
10.1089/cap.2000.10.311
10.1046/j.1471-4159.2002.00820.x
10.1016/0014-5793(91)81406-X
10.1016/j.pneurobio.2005.04.003
10.1016/S1353-8020(13)70011-7
10.1176/appi.ajp.2011.11010126
10.1523/JNEUROSCI.5298-09.2010
10.1111/j.1471-4159.2009.06135.x
10.1016/j.tins.2004.03.011
10.1021/bi700429z
10.1111/j.1471-4159.1993.tb02185.x
10.1016/j.ejphar.2003.08.060
10.1111/j.1600-0854.2008.00771.x
10.1172/JCI73778
10.1523/JNEUROSCI.4778-04.2005
10.1093/brain/114.5.2283
10.1001/archpsyc.63.7.824
10.1016/S0021-9258(19)69274-4
10.1046/j.1471-4159.2002.00893.x
10.1016/S0022-3565(25)24030-7
10.1046/j.1471-4159.1996.67020593.x
10.1212/01.WNL.0000126440.16612.51
10.1083/jcb.152.6.1159
10.1124/jpet.111.191056
10.1111/j.1471-4159.2006.04326.x
10.1038/sj.jcbfm.9600276
10.1016/0140-6736(92)90730-Q
10.1046/j.1471-4159.2001.00284.x
10.1124/jpet.102.045005
10.1371/journal.pone.0025790
10.1146/annurev.cellbio.15.1.733
10.1208/aapsj070481
10.1124/pr.108.000869
10.1111/j.1476-5381.1977.tb08395.x
10.1016/S0014-2999(98)00008-9
10.1002/jnr.21125
10.1371/journal.pbio.0020078
10.1016/S0021-9258(19)69022-8
10.1016/S0896-6273(01)00267-7
10.1016/j.mcn.2008.06.011
10.1038/clpt.2010.307
10.1074/jbc.M200294200
10.1016/j.drugalcdep.2009.09.002
10.1111/j.1360-0443.2006.01782.x
10.1016/j.neuroscience.2013.11.059
10.1016/j.neuron.2006.06.028
10.5483/BMBRep.2014.47.7.086
10.1073/pnas.89.22.10993
10.1523/JNEUROSCI.19-18-07699.1999
10.1371/journal.pone.0060763
10.1007/7854_2010_93
10.1073/pnas.181344298
10.1176/appi.ajp.160.1.47
10.1523/JNEUROSCI.3008-08.2008
10.1093/oxfordjournals.schbul.a033504
10.1046/j.1471-4159.1995.64041819.x
10.1016/j.biopsych.2012.03.022
10.1007/BF00998279
10.1016/S1054-3589(08)57007-4
10.1038/nature12533
10.1074/jbc.274.50.35794
10.1126/science.2820058
10.1126/science.276.5321.2045
10.1016/j.nbd.2009.09.002
10.1016/j.pharmthera.2009.06.014
10.1016/S0022-3565(24)29365-4
10.1074/jbc.M210652200
10.1097/00004714-200110000-00010
10.1038/sj.mp.4000711
10.1016/j.jaac.2010.05.017
10.1016/S0006-3223(00)00981-1
10.1111/j.1471-4159.2009.05910.x
10.1001/jama.2009.1308
10.1038/nn.2146
10.1016/j.neuropharm.2004.07.007
10.1007/s11065-007-9019-9
10.1111/j.1365-2265.2009.03586.x
10.1056/NEJMoa1207281
10.1074/jbc.M110.187872
10.1208/aapsj080124
10.1016/S0140-6736(99)04030-1
10.1016/S0014-2999(97)01175-8
10.1016/S0022-3565(24)38814-7
10.1074/jbc.M110.131003
10.1124/jpet.110.173260
10.1124/jpet.109.154302
10.1016/j.drugalcdep.2008.04.014
10.1074/jbc.272.10.6752
10.1016/S0022-3565(25)27006-9
10.1016/j.neuropharm.2005.08.018
10.1016/j.neuropharm.2012.02.005
10.1016/S0014-2999(03)02080-6
10.1016/j.neuron.2011.02.010
10.1126/science.133.3458.1072
10.1016/0006-2952(75)90152-5
10.1046/j.1471-4159.2000.0742217.x
10.1016/S1474-4422(10)70269-6
10.1124/jpet.105.091231
10.1016/j.drugalcdep.2008.10.016
10.1001/archpsyc.62.6.617
10.1001/jamapsychiatry.2013.277
10.1124/jpet.111.185025
10.1016/S0022-3565(24)39008-1
10.1074/jbc.M506618200
10.1111/j.1471-4159.2007.04837.x
10.1111/j.1749-6632.2009.05118.x
10.1124/pr.109.002071
10.1038/nchembio.1545
10.1523/JNEUROSCI.18-20-08417.1998
10.1091/mbc.e06-08-0704
10.1126/science.1948034
10.1074/jbc.M205058200
10.1016/S0169-328X(97)00116-2
10.1021/bi801696n
10.1016/S0022-3565(24)37287-8
10.1038/npp.2009.110
10.1093/ijnp/pyv024
10.1124/jpet.104.072264
10.1016/j.npep.2008.04.003
10.1016/0091-3057(88)90354-1
10.1111/j.1471-4159.1993.tb03181.x
10.1016/S0006-8993(02)04087-8
10.1074/jbc.M201926200
10.1016/S0165-6147(99)01379-6
10.1124/jpet.113.208264
10.1111/j.1360-0443.2009.02717.x
10.1016/0165-3806(94)90178-3
10.1111/j.1471-4159.2010.06599.x
10.1037/1064-1297.10.3.286
10.1073/pnas.110035297
10.1074/jbc.M111.294702
10.1074/jbc.271.35.21672
10.1523/JNEUROSCI.22-19-08705.2002
10.1111/j.1600-0854.2005.00259.x
10.1124/mol.107.039800
10.1186/1750-2187-1-5
10.1038/tp.2014.90
10.1016/S0024-3205(03)00388-6
10.1038/nn920
10.1038/sj.mp.4000290
10.1073/pnas.0407737102
10.1016/0006-8993(94)91698-5
10.1016/j.pnpbp.2013.01.016
10.1016/j.spen.2010.10.005
10.1007/s00213-002-1183-2
10.1073/pnas.92.19.8773
10.1038/379606a0
10.1124/jpet.107.126888
10.1146/annurev.neuro.20.1.125
10.1016/S0010-440X(96)90054-1
10.1124/jpet.108.145813
10.1111/j.1471-4159.2008.05262.x
10.1073/pnas.1417294111
10.1016/j.ejphar.2011.02.027
10.1073/pnas.93.10.5166
10.1097/00004850-199010000-00001
10.1016/j.ejphar.2004.09.049
10.1016/j.brainresrev.2008.02.004
10.1021/jm901189z
10.1038/ncomms2568
10.1007/s00213-006-0330-6
10.1001/archgenpsychiatry.2009.137
10.1002/syn.20075
10.1016/0006-2952(68)90354-7
10.1523/JNEUROSCI.21-04-01413.2001
10.1001/archpsyc.64.8.932
10.1073/pnas.95.7.4029
10.1016/j.mcn.2010.08.016
10.1586/14737175.6.4.455
10.1038/sj.emboj.7601656
10.1016/S0304-3940(96)12963-3
10.1523/JNEUROSCI.1863-04.2004
10.1097/00004714-199712000-00008
10.1016/j.brainres.2009.12.093
10.1523/JNEUROSCI.5456-13.2014
10.1016/S0014-2999(00)00639-7
10.1038/npp.2010.167
10.1074/jbc.M409282200
10.1016/j.neuropharm.2005.08.003
10.1016/S0022-3999(02)00308-2
10.1038/nn.2781
10.1016/j.neuropharm.2009.08.013
10.1038/nature07605
10.1124/jpet.110.166660
10.1111/j.1471-4159.2005.03289.x
10.1523/JNEUROSCI.4177-08.2009
10.1093/brain/awu022
10.1523/JNEUROSCI.16-02-00436.1996
10.1523/JNEUROSCI.17-03-00960.1997
10.1016/j.drugalcdep.2011.06.013
10.1523/JNEUROSCI.1301-06.2006
10.1111/jnc.13025
10.1016/S0022-3565(24)36962-9
10.1126/science.1147614
10.1523/JNEUROSCI.20-19-07297.2000
10.1523/JNEUROSCI.6033-11.2012
10.1074/jbc.272.24.15541
10.1046/j.1471-4159.2002.00892.x
10.1523/JNEUROSCI.16-13-04135.1996
10.1007/s11910-013-0362-3
10.1371/journal.pbio.0050274
10.1016/j.ejphar.2008.07.002
10.1002/(SICI)1098-108X(199609)20:2<163::AID-EAT6>3.0.CO;2-E
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References Li, Chen, Ramamoorthy, Chi, Cui, Wang, Reith (bib146) 2004; 279
Takahashi, Uhl (bib242) 1997; 49
Loder, Melikian (bib152) 2003; 278
Bossé, Rivest, Di Paolo (bib17) 1997; 46
Carvelli, Morón, Kahlig, Ferrer, Sen, Lechleiter, Leeb-Lundberg, Merrill, Lafer, Ballou (bib30) 2002; 81
Mash, Pablo, Ouyang, Hearn, Izenwasser (bib159) 2002; 81
Mooney, Herin, Schmitz, Moukaddam, Green, Grabowski (bib174) 2009; 101
Richards, Zahniser (bib208) 2009; 108
Hamilton, Belovich, Khelashvili, Saunders, Erreger, Javitch, Sitte, Weinstein, Matthies, Galli (bib102) 2014; 10
Nirenberg, Chan, Vaughan, Uhl, Kuhar, Pickel (bib186) 1997; 17
Volz, Schenk (bib262) 2004; 54
Lynch, Roth, Carroll (bib156) 2002; 164
Crits-Christoph, Newberg, Wintering, Ploessl, Gibbons, Ring-Kurtz, Gallop, Present (bib41) 2008; 98
Floor, Meng (bib74) 1996; 215
Eriksen, Bjørn-Yoshimoto, Jørgensen, Newman, Gether (bib57) 2010; 285
Lee, Liu, Pristupa, Niznik (bib142) 2001; 15
Nickell, Siripurapu, Vartak, Crooks, Dwoskin (bib182) 2014; 69
Johnson, Furman, Zhang, Guptaroy, Gnegy (bib124) 2005; 49
Sonders, Zhu, Zahniser, Kavanaugh, Amara (bib232) 1997; 17
Brown, Hanson, Fleckenstein (bib21) 2000; 74
Foster, Pananusorn, Vaughan (bib77) 2002; 277
Barrett, Miller, Dohrmann, Caine (bib8) 2004; 47
Franko, Dorer, Keel, Jackson, Manzo, Herzog (bib82) 2008; 196
Daws, Callaghan, Morón, Kahlig, Shippenberg, Javitch, Galli (bib45) 2002; 290
Sevak, Koek, Owens, Galli, Daws, France (bib226) 2008; 592
Curtin, Fleckenstein, Robison, Crookston, Smith, Hanson (bib42) 2015; 146
Figlewicz, Evans, Murphy, Hoen, Baskin (bib67) 2003; 964
Milner, Béliveau, Jarvis (bib171) 1994; 1190
Weyandt, Oster, Marraccini, Gudmundsdottir, Munro, Zavras, Kuhar (bib267) 2014; 7
Kahlig, Binda, Khoshbouei, Blakely, McMahon, Javitch, Galli (bib128) 2005; 102
Sorkina, Hoover, Zahniser, Sorkin (bib234) 2005; 6
Torres, Ruoho (bib247) 2014; 259
Schubiner, Saules, Arfken, Johanson, Schuster, Lockhart, Edwards, Donlin, Pihlgren (bib224) 2002; 10
Snyder, Glowinski, Axelrod (bib230) 1965; 4
Ling, Chang, Hillhouse, Ang, Striebel, Jenkins, Hernandez, Olaer, Mooney, Reed (bib149) 2014; 109
Boileau, Rusjan, Houle, Wilkins, Tong, Selby, Guttman, Saint-Cyr, Wilson, Kish (bib16) 2008; 28
Ishibashi, Oda, Ishiwata, Ishii (bib121) 2014; 339
Zubieta, Taylor, Huguelet, Koeppe, Kilbourn, Frey (bib280) 2001; 49
Chang, Alicata, Ernst, Volkow (bib31) 2007; 102
Kantor, Gnegy (bib283) 1998; 284
Fleckenstein, Haughey, Metzger, Kokoshka, Riddle, Hanson, Gibb, Hanson (bib282) 1999; 382
Harrod, Dwoskin, Crooks, Klebaur, Bardo (bib106) 2001; 298
Fearnley, Lees (bib64) 1991; 114
Loland, Desai, Zou, Cao, Grundt, Gerstbrein, Sitte, Newman, Katz, Gether (bib153) 2008; 73
Penmatsa, Wang, Gouaux (bib195) 2013; 503
Vaughan, Huff, Uhl, Kuhar (bib254) 1997; 272
Patel, Cerruti, Vaughan, Kuhar (bib193) 1994; 83
Zhu, Kavanaugh, Sonders, Amara, Zahniser (bib278) 1997; 282
Foster, Yang, Moritz, Challasivakanaka, Smith, Holy, Wilebski, Sitte, Vaughan (bib79) 2012; 287
Kurian, Li, Zhen, Meyer, Hai, Christen, Hoffmann, Jardine, von Moers, Mordekar (bib139) 2011; 10
Bohnen, Albin, Koeppe, Wernette, Kilbourn, Minoshima, Frey (bib15) 2006; 26
Carroll, Blough, Abraham, Mills, Holleman, Wolckenhauer, Decker, Landavazo, McElroy, Navarro (bib27) 2009; 52
Chu, Hadlock, Vieira-Brock, Stout, Hanson, Fleckenstein (bib35) 2010; 115
Nakamura, Sekine, Ouchi, Tsujii, Yoshikawa, Futatsubashi, Tsuchiya, Sugihara, Iwata, Suzuki (bib177) 2010; 67
Rilstone, Alkhater, Minassian (bib214) 2013; 368
Ingram, Prasad, Amara (bib120) 2002; 5
Brown, Hanson, Fleckenstein (bib22) 2001; 298
Johanson, Frey, Lundahl, Keenan, Lockhart, Roll, Galloway, Koeppe, Kilbourn, Robbins (bib123) 2006; 185
Taylor, Russo (bib245) 2000; 10
Torres, Yao, Mohn, Quan, Kim, Levey, Staudinger, Caron (bib249) 2001; 30
Lee, Pei, Moszczynska, Vukusic, Fletcher, Liu (bib143) 2007; 26
Li, Kopajtic, O’Callaghan, Agoston, Cao, Newman, Katz (bib147) 2011; 336
Schmitt, Reith (bib222) 2011; 6
Truong, Newman, Hanson, Fleckenstein (bib250) 2004; 504
Colburn, Goodwin, Murphy, Bunney, Davis (bib36) 1968; 17
McCann, Wong, Yokoi, Villemagne, Dannals, Ricaurte (bib162) 1998; 18
Hiranita, Kohut, Soto, Tanda, Kopajtic, Katz (bib111) 2014; 348
Vosburg, Hart, Haney, Rubin, Foltin (bib263) 2010; 106
Berman, Zigmond, Hastings (bib10) 1996; 67
Volkow, Wang, Kollins, Wigal, Newcorn, Telang, Fowler, Zhu, Logan, Ma (bib258) 2009; 302
Guillot, Richardson, Wang, Li, Taylor, Ciliax, Zachrisson, Mercer, Miller (bib99) 2008; 42
Sakrikar, Mazei-Robison, Mergy, Richtand, Han, Hamilton, Bowton, Galli, Veenstra-Vanderweele, Gill (bib218) 2012; 32
Rickhag, Hansen, Sørensen, Strandfelt, Andresen, Gotfryd, Madsen, Vestergaard-Klewe, Ammendrup-Johnsen, Eriksen (bib210) 2013; 4
Ng, Zhen, Meyer, Erreger, Li, Kakar, Ahmad, Thiele, Kubisch, Rider (bib180) 2014; 137
Reith, Blough, Hong, Jones, Schmitt, Baumann, Partilla, Rothman, Katz (bib204) 2015; 147
Hiranita, Soto, Newman, Katz (bib113) 2009; 329
Holton, Loder, Melikian (bib115) 2005; 8
Foster, Adkins, Lever, Vaughan (bib76) 2008; 105
Bowton, Saunders, Reddy, Campbell, Hamilton, Henry, Coon, Sakrikar, Veenstra-VanderWeele, Blakely (bib19) 2014; 4
Callaghan, Cunningham, Sykes, Kish (bib25) 2012; 120
Khoshbouei, Sen, Guptaroy, Johnson, Lund, Gnegy, Galli, Javitch (bib131) 2004; 2
Bjerggaard, Fog, Hastrup, Madsen, Loland, Javitch, Gether (bib13) 2004; 24
Grünhage, Schulze, Müller, Lanczik, Franzek, Albus, Borrmann-Hassenbach, Knapp, Cichon, Maier (bib98) 2000; 5
Owens, Sevak, Galici, Chang, Javors, Galli, France, Daws (bib192) 2005; 94
Cameron, Williams (bib26) 1993; 366
Zhen, Antonio, Cheng, Ali, Jones, Reith (bib276) 2015; 133
Chavez, Hollaus, Scarr, Pavey, Gogos, van den Buuse (bib33) 2010; 1321
Merikangas, He, Burstein, Swanson, Avenevoli, Cui, Benjet, Georgiades, Swendsen (bib168) 2010; 49
Liu, Edwards (bib151) 1997; 20
Rice, Cragg (bib207) 2008; 58
Brown, Hanson, Fleckenstein (bib23) 2001; 296
Wiederman, Pryor (bib269) 1996; 20
Nirenberg, Chan, Liu, Edwards, Pickel (bib184) 1996; 16
Frey, Koeppe, Kilbourn (bib83) 2001; 86
Tanda, Newman, Katz (bib244) 2009; 57
Bernstein, Stout, Miller (bib11) 2014; 73
Fleckenstein, Gibb, Hanson (bib70) 2000; 406
Baladi, Horton, Owens, Daws, France (bib7) 2015; 18
Boudanova, Navaroli, Stevens, Melikian (bib18) 2008; 39
Baladi, Daws, France (bib6) 2012; 63
Nguyen, Roth, Kyzar, Poudel, Wong, Stewart, Kalueff (bib181) 2014; 66
Bobb, Addington, Sidransky, Gornick, Lerch, Greenstein, Clasen, Sharp, Inoff-Germain, Wavrant-De Vrièze (bib14) 2005; 134B
Tanda, Newman, Ebbs, Tronci, Green, Tallarida, Katz (bib243) 2009; 330
Kristensen, Andersen, Jørgensen, Sørensen, Eriksen, Loland, Strømgaard, Gether (bib137) 2011; 63
Shan, Javitch, Shi, Weinstein (bib227) 2011; 6
Wheeler, Edwards, Chapman, Ondo (bib268) 1993; 18
Miranda, Dionne, Sorkina, Sorkin (bib172) 2007; 18
Schmitt, Rothman, Reith (bib223) 2013; 346
Hiranita, Soto, Kohut, Kopajtic, Cao, Newman, Tanda, Katz (bib112) 2011; 339
Søgaard, Michalow, Butler, Lund Laursen, Ingersen, Skrumsager, Rafaelsen (bib231) 1990; 5
Chang, Lee, Kim, Lee, Kim, Son, Lee (bib32) 2001; 77
Mukherjee, Decina, Bocola, Saraceni, Scapicchio (bib176) 1996; 37
Eyerman, Yamamoto (bib60) 2005; 312
Suzuki, Desmond, Albin, Frey (bib240) 2001; 41
Zhou, Zhen, Karpowich, Goetz, Law, Reith, Wang (bib277) 2007; 317
Furman, Chen, Guptaroy, Zhang, Holz, Gnegy (bib84) 2009; 29
Giros, el Mestikawy, Bertrand, Caron (bib90) 1991; 295
Volkow, Wang, Newcorn, Telang, Solanto, Fowler, Logan, Ma, Schulz, Pradhan (bib260) 2007; 64
Knoth, Isaacs, Njus (bib133) 1981; 256
Truong, Rau, Hanson, Fleckenstein (bib251) 2003; 474
Pifl, Rajput, Reither, Blesa, Cavada, Obeso, Rajput, Hornykiewicz (bib197) 2014; 34
Torres, Carneiro, Seamans, Fiorentini, Sweeney, Yao, Caron (bib248) 2003; 278
Gillies, McArthur (bib88) 2010; 62
Covey, Juliano, Garris (bib38) 2013; 8
Levey, Hersch, Rye, Sunahara, Niznik, Kitt, Price, Maggio, Brann, Ciliax (bib144) 1993; 90
Figlewicz (bib66) 2003; 8
Gill, Daly, Heron, Hawi, Fitzgerald (bib87) 1997; 2
Metzger, Haughey, Wilkins, Gibb, Hanson, Fleckenstein (bib169) 2000; 295
Eyerman, Yamamoto (bib61) 2007; 103
Gorentla, Moritz, Foster, Vaughan (bib94) 2009; 48
Anker, Carroll (bib4) 2011; 8
Vaughan, Kuhar (bib255) 1996; 271
Granas, Ferrer, Loland, Javitch, Gether (bib97) 2003; 278
Fei, Grygoruk, Brooks, Chen, Krantz (bib65) 2008; 9
Faith, Matz, Jorge (bib63) 2002; 53
Huang, Zhou, Chase, Gusella, Aronin, DiFiglia (bib119) 1992; 89
Mazei-Robison, Couch, Shelton, Stein, Blakely (bib161) 2005; 49
Rothman, Partilla, Baumann, Lightfoot-Siordia, Blough (bib216) 2012; 341
Beuming, Kniazeff, Bergmann, Shi, Gracia, Raniszewska, Newman, Javitch, Weinstein, Gether (bib12) 2008; 11
Nirenberg, Chan, Liu, Edwards, Pickel (bib185) 1997; 26
Hogan, Staal, Sonsalla (bib114) 2000; 74
Miranda, Wu, Sorkina, Korstjens, Sorkin (bib173) 2005; 280
Carroll, Howard, Howell, Fox, Kuhar (bib28) 2006; 8
Assmann, Robinson, Surtees, Bräutigam, Heales, Wevers, Zschocke, Hyland, Sharma, Hoffmann (bib5) 2004; 62
Sulzer, Sonders, Poulsen, Galli (bib239) 2005; 75
Rao, Simmons, Sorkin (bib202) 2011; 46
Reith, Berfield, Wang, Ferrer, Javitch (bib203) 2001; 276
Fleckenstein, Metzger, Beyeler, Gibb, Hanson (bib71) 1997; 334
Jones, Gainetdinov, Jaber, Giros, Wightman, Caron (bib126) 1998; 95
Daws, Avison, Robertson, Niswender, Galli, Saunders (bib44) 2011; 61
Desai, Kopajtic, Koffarnus, Newman, Katz (bib49) 2005; 25
Sandoval, Riddle, Hanson, Fleckenstein (bib219) 2002; 22
Rickhag, Owens, Winkler, Strandfelt, Rathje, Sørensen, Andresen, Madsen, Jørgensen, Wörtwein (bib211) 2013; 288
Hanson, Hoonakker, Robson, McFadden, Frankel, Alburges (bib105) 2013; 346
Dougherty, Bonab, Spencer, Rauch, Madras, Fischman (bib52) 1999; 354
Kang, Wan, Arstikaitis, Takahashi, Huang, Bailey, Thompson, Roth, Drisdel, Mastro (bib129) 2008; 456
Wilson, Levey, Bergeron, Kalasinsky, Ang, Peretti, Adams, Smialek, Anderson, Shannak (bib272) 1996; 40
Hart, Radua, Nakao, Mataix-Cols, Rubia (bib107) 2013; 70
Riddle, Fleckenstein, Hanson (bib212) 2005; 7
Jones, Joseph, Barak, Caron, Wightman (bib127) 1999; 73
Patterson, Brot, Zavosh, Schenk, Szot, Figlewicz (bib194) 1998; 68
Volz, Fa
Eriksen (10.1124/pr.114.010397_bib59) 2009; 29
Takahashi (10.1124/pr.114.010397_bib242) 1997; 49
Frank (10.1124/pr.114.010397_bib81) 2010; 70
Sorkina (10.1124/pr.114.010397_bib235) 2006; 26
Figlewicz (10.1124/pr.114.010397_bib67) 2003; 964
Mergy (10.1124/pr.114.010397_bib167) 2014; 111
Beuming (10.1124/pr.114.010397_bib12) 2008; 11
Covey (10.1124/pr.114.010397_bib38) 2013; 8
Adkins (10.1124/pr.114.010397_bib1) 2007; 46
Brown (10.1124/pr.114.010397_bib21) 2000; 74
Loder (10.1124/pr.114.010397_bib152) 2003; 278
Zubieta (10.1124/pr.114.010397_bib280) 2001; 49
Chavez (10.1124/pr.114.010397_bib33) 2010; 1321
Fiorino (10.1124/pr.114.010397_bib69) 1993; 55
Liu (10.1124/pr.114.010397_bib151) 1997; 20
Desai (10.1124/pr.114.010397_bib48) 2005; 315
Floor (10.1124/pr.114.010397_bib74) 1996; 215
Merikangas (10.1124/pr.114.010397_bib168) 2010; 49
Turner (10.1124/pr.114.010397_bib252) 2006; 6
Krause (10.1124/pr.114.010397_bib136) 2000; 285
McCann (10.1124/pr.114.010397_bib162) 1998; 18
Fog (10.1124/pr.114.010397_bib75) 2006; 51
Yao (10.1124/pr.114.010397_bib274) 2007; 100
Cho (10.1124/pr.114.010397_bib34) 2009; 71
Levey (10.1124/pr.114.010397_bib144) 1993; 90
Peter (10.1124/pr.114.010397_bib196) 1994; 269
Mukherjee (10.1124/pr.114.010397_bib176) 1996; 37
Kilty (10.1124/pr.114.010397_bib132) 1991; 254
Curtin (10.1124/pr.114.010397_bib42) 2015; 146
Zhou (10.1124/pr.114.010397_bib277) 2007; 317
Sulzer (10.1124/pr.114.010397_bib238) 1993; 60
German (10.1124/pr.114.010397_bib86) 2012; 123
Madsen (10.1124/pr.114.010397_bib157) 2012; 287
Sulzer (10.1124/pr.114.010397_bib239) 2005; 75
Volkow (10.1124/pr.114.010397_bib257) 2001; 158
Facchini (10.1124/pr.114.010397_bib62) 1992; 339
Zhu (10.1124/pr.114.010397_bib278) 1997; 282
Cartier (10.1124/pr.114.010397_bib29) 2010; 285
Jones (10.1124/pr.114.010397_bib126) 1998; 95
Sandoval (10.1124/pr.114.010397_bib219) 2002; 22
Penmatsa (10.1124/pr.114.010397_bib195) 2013; 503
Desai (10.1124/pr.114.010397_bib49) 2005; 25
Cragg (10.1124/pr.114.010397_bib39) 2004; 27
Polymeropoulos (10.1124/pr.114.010397_bib199) 1997; 276
Kurian (10.1124/pr.114.010397_bib139) 2011; 10
Rothman (10.1124/pr.114.010397_bib216) 2012; 341
Mayfield (10.1124/pr.114.010397_bib160) 2001; 59
Swanson (10.1124/pr.114.010397_bib241) 2007; 17
Eriksen (10.1124/pr.114.010397_bib58) 2010; 113
Watson (10.1124/pr.114.010397_bib266) 1999; 220
Nirenberg (10.1124/pr.114.010397_bib184) 1996; 16
Foster (10.1124/pr.114.010397_bib79) 2012; 287
Sakrikar (10.1124/pr.114.010397_bib218) 2012; 32
Weyandt (10.1124/pr.114.010397_bib267) 2014; 7
Kang (10.1124/pr.114.010397_bib129) 2008; 456
Galloway (10.1124/pr.114.010397_bib85) 2011; 89
Disshon (10.1124/pr.114.010397_bib50) 1998; 345
Baucum (10.1124/pr.114.010397_bib9) 2004; 24
Kufahl (10.1124/pr.114.010397_bib138) 2011; S1
Baladi (10.1124/pr.114.010397_bib6) 2012; 63
Fountaine (10.1124/pr.114.010397_bib80) 2007; 85
Ng (10.1124/pr.114.010397_bib180) 2014; 137
Torres (10.1124/pr.114.010397_bib248) 2003; 278
Huang (10.1124/pr.114.010397_bib119) 1992; 89
Metzger (10.1124/pr.114.010397_bib169) 2000; 295
Mooney (10.1124/pr.114.010397_bib174) 2009; 101
Milner (10.1124/pr.114.010397_bib171) 1994; 1190
Ingram (10.1124/pr.114.010397_bib120) 2002; 5
Patterson (10.1124/pr.114.010397_bib194) 1998; 68
Gill (10.1124/pr.114.010397_bib87) 1997; 2
Anker (10.1124/pr.114.010397_bib4) 2011; 8
Dougherty (10.1124/pr.114.010397_bib52) 1999; 354
Johnson (10.1124/pr.114.010397_bib124) 2005; 49
Fleckenstein (10.1124/pr.114.010397_bib72) 1997; 282
Hannah (10.1124/pr.114.010397_bib103) 1999; 15
Dixon (10.1124/pr.114.010397_bib51) 2000; 26
Watson (10.1124/pr.114.010397_bib265) 2006; 1
Carvelli (10.1124/pr.114.010397_bib30) 2002; 81
Fleckenstein (10.1124/pr.114.010397_bib282) 1999; 382
Bossé (10.1124/pr.114.010397_bib17) 1997; 46
McGuire (10.1124/pr.114.010397_bib164) 2011; 658
Miranda (10.1124/pr.114.010397_bib173) 2005; 280
Truong (10.1124/pr.114.010397_bib250) 2004; 504
Volkow (10.1124/pr.114.010397_bib258) 2009; 302
Chang (10.1124/pr.114.010397_bib31) 2007; 102
Marek (10.1124/pr.114.010397_bib158) 1990; 516
Nakamura (10.1124/pr.114.010397_bib177) 2010; 67
Schmitt (10.1124/pr.114.010397_bib223) 2013; 346
Sulzer (10.1124/pr.114.010397_bib237) 2011; 69
Torres (10.1124/pr.114.010397_bib249) 2001; 30
Rickhag (10.1124/pr.114.010397_bib211) 2013; 288
Spatola (10.1124/pr.114.010397_bib236) 2014; 20
Schmitt (10.1124/pr.114.010397_bib222) 2011; 6
Bohnen (10.1124/pr.114.010397_bib15) 2006; 26
Lee (10.1124/pr.114.010397_bib143) 2007; 26
Sandoval (10.1124/pr.114.010397_bib220) 2003; 304
Glowinski (10.1124/pr.114.010397_bib93) 1965; 12
Kristensen (10.1124/pr.114.010397_bib137) 2011; 63
Truong (10.1124/pr.114.010397_bib251) 2003; 474
Boileau (10.1124/pr.114.010397_bib16) 2008; 28
Longo (10.1124/pr.114.010397_bib155) 2010; 105
Pletscher (10.1124/pr.114.010397_bib198) 1977; 59
Hadlock (10.1124/pr.114.010397_bib100) 2010; 335
Zhen (10.1124/pr.114.010397_bib276) 2015; 133
Figlewicz (10.1124/pr.114.010397_bib66) 2003; 8
Eyerman (10.1124/pr.114.010397_bib60) 2005; 312
Haughey (10.1124/pr.114.010397_bib109) 1999; 379
Bjerggaard (10.1124/pr.114.010397_bib13) 2004; 24
Suzuki (10.1124/pr.114.010397_bib240) 2001; 41
Chang (10.1124/pr.114.010397_bib32) 2001; 77
Grabowski (10.1124/pr.114.010397_bib95) 2001; 21
Brown (10.1124/pr.114.010397_bib24) 2002; 302
Daws (10.1124/pr.114.010397_bib45) 2002; 290
Sonders (10.1124/pr.114.010397_bib232) 1997; 17
Crits-Christoph (10.1124/pr.114.010397_bib41) 2008; 98
Boudanova (10.1124/pr.114.010397_bib18) 2008; 39
Bowton (10.1124/pr.114.010397_bib19) 2014; 4
Foster (10.1124/pr.114.010397_bib77) 2002; 277
Volkow (10.1124/pr.114.010397_bib259) 2007; 34
Knoth (10.1124/pr.114.010397_bib133) 1981; 256
Daniels (10.1124/pr.114.010397_bib43) 1999; 274
Patel (10.1124/pr.114.010397_bib193) 1994; 83
Figlewicz (10.1124/pr.114.010397_bib68) 1994; 644
Miranda (10.1124/pr.114.010397_bib172) 2007; 18
Holton (10.1124/pr.114.010397_bib115) 2005; 8
Kahlig (10.1124/pr.114.010397_bib128) 2005; 102
Zubieta (10.1124/pr.114.010397_bib279) 2000; 157
Nirenberg (10.1124/pr.114.010397_bib187) 1995; 92
Johnson (10.1124/pr.114.010397_bib125) 1981; 256
Reith (10.1124/pr.114.010397_bib204) 2015; 147
Schubiner (10.1124/pr.114.010397_bib224) 2002; 10
Onoa (10.1124/pr.114.010397_bib191) 2010; 30
Søgaard (10.1124/pr.114.010397_bib231) 1990; 5
Carroll (10.1124/pr.114.010397_bib27) 2009; 52
Li (10.1124/pr.114.010397_bib146) 2004; 279
Granas (10.1124/pr.114.010397_bib97) 2003; 278
Williams (10.1124/pr.114.010397_bib271) 2007; 5
Seeman (10.1124/pr.114.010397_bib225) 1990; 4
Fleckenstein (10.1124/pr.114.010397_bib71) 1997; 334
Lynch (10.1124/pr.114.010397_bib156) 2002; 164
Carroll (10.1124/pr.114.010397_bib28) 2006; 8
Chu (10.1124/pr.114.010397_bib35) 2010; 115
Hanson (10.1124/pr.114.010397_bib105) 2013; 346
Nickell (10.1124/pr.114.010397_bib182) 2014; 69
Fleckenstein (10.1124/pr.114.010397_bib70) 2000; 406
Sevak (10.1124/pr.114.010397_bib226) 2008; 592
Little (10.1124/pr.114.010397_bib150) 2003; 160
Fearnley (10.1124/pr.114.010397_bib64) 1991; 114
Sorkina (10.1124/pr.114.010397_bib233) 2003; 278
Hong (10.1124/pr.114.010397_bib116) 2010; 285
Brown (10.1124/pr.114.010397_bib23) 2001; 296
Wheeler (10.1124/pr.114.010397_bib268) 1993; 18
Volz (10.1124/pr.114.010397_bib262) 2004; 54
Omiatek (10.1124/pr.114.010397_bib190) 2013; 3
Tanda (10.1124/pr.114.010397_bib243) 2009; 330
Richards (10.1124/pr.114.010397_bib208) 2009; 108
Harrod (10.1124/pr.114.010397_bib106) 2001; 298
Volkow (10.1124/pr.114.010397_bib260) 2007; 64
Pothos (10.1124/pr.114.010397_bib200) 2000; 20
Riddle (10.1124/pr.114.010397_bib212) 2005; 7
Snyder (10.1124/pr.114.010397_bib230) 1965; 4
Eriksen (10.1124/pr.114.010397_bib57) 2010; 285
Khoshbouei (10.1124/pr.114.010397_bib131) 2004; 2
Nguyen (10.1124/pr.114.010397_bib181) 2014; 66
Giros (10.1124/pr.114.010397_bib90) 1991; 295
Hart (10.1124/pr.114.010397_bib107) 2013; 70
Johanson (10.1124/pr.114.010397_bib123) 2006; 185
Owens (10.1124/pr.114.010397_bib192) 2005; 94
Shan (10.1124/pr.114.010397_bib227) 2011; 6
Loland (10.1124/pr.114.010397_bib153) 2008; 73
Moszczynska (10.1124/pr.114.010397_bib175) 2007; 32
Nirenberg (10.1124/pr.114.010397_bib188) 1996; 16
Foster (10.1124/pr.114.010397_bib76) 2008; 105
Wigal (10.1124/pr.114.010397_bib270) 2010; 17
Eyerman (10.1124/pr.114.010397_bib61) 2007; 103
Hiranita (10.1124/pr.114.010397_bib112) 2011; 339
Cameron (10.1124/pr.114.010397_bib26) 1993; 366
Wilson (10.1124/pr.114.010397_bib272) 1996; 40
Vaughan (10.1124/pr.114.010397_bib253) 2013; 34
Melikian (10.1124/pr.114.010397_bib166) 1999; 19
Barrett (10.1124/pr.114.010397_bib8) 2004; 47
Callaghan (10.1124/pr.114.010397_bib25) 2012; 120
Gillies (10.1124/pr.114.010397_bib88) 2010; 62
Tiihonen (10.1124/pr.114.010397_bib246) 2007; 164
Howell (10.1124/pr.114.010397_bib118) 2014; 69
Kurian (10.1124/pr.114.010397_bib140) 2009; 119
Meiergerd (10.1124/pr.114.010397_bib165) 1993; 61
Grabowski (10.1124/pr.114.010397_bib96) 1997; 17
Halliday (10.1124/pr.114.010397_bib101) 2010; 1184
Velázquez-Sánchez (10.1124/pr.114.010397_bib256) 2013; 44
Heikkila (10.1124/pr.114.010397_bib110) 1975; 24
Kantor (10.1124/pr.114.010397_bib283) 1998; 284
Franko (10.1124/pr.114.010397_bib82) 2008; 196
Loland (10.1124/pr.114.010397_bib154) 2012; 72
Afonso-Oramas (10.1124/pr.114.010397_bib2) 2009; 36
Pifl (10.1124/pr.114.010397_bib197) 2014; 34
Berman (10.1124/pr.114.010397_bib10) 1996; 67
Wiederman (10.1124/pr.114.010397_bib269) 1996; 20
Pramod (10.1124/pr.114.010397_bib201) 2013; 34
Bernstein (10.1124/pr.114.010397_bib11) 2014; 73
de la Fuente-Fernández (10.1124/pr.114.010397_bib46) 2011; 69
Vaughan (10.1124/pr.114.010397_bib254) 1997; 272
Copeland (10.1124/pr.114.010397_bib37) 1996; 277
Guillot (10.1124/pr.114.010397_bib99) 2008; 42
Levitt (10.1124/pr.114.010397_bib145) 1965; 148
Mazei-Robison (10.1124/pr.114.010397_bib161) 2005; 49
Assmann (10.1124/pr.114.010397_bib5) 2004; 62
Fleckenstein (10.1124/pr.114.010397_bib73) 2007; 47
Reith (10.1124/pr.114.010397_bib203) 2001; 276
Cervinski (10.1124/pr.114.010397_bib281) 2005; 280
Dengler (10.1124/pr.114.010397_bib47) 1961; 133
Furman (10.1124/pr.114.010397_bib84) 2009; 29
Jones (10.1124/pr.114.010397_bib127) 1999; 73
Reith (10.1124/pr.114.010397_bib205)
References_xml – volume: 103
  start-page: 1219
  year: 2007
  end-page: 1227
  ident: bib61
  article-title: A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine
  publication-title: J Neurochem
– volume: 256
  start-page: 5773
  year: 1981
  end-page: 5780
  ident: bib125
  article-title: Proton: substrate stoichiometries during active transport of biogenic amines in chromaffin ghosts
  publication-title: J Biol Chem
– volume: 49
  start-page: 110
  year: 2001
  end-page: 116
  ident: bib280
  article-title: Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects
  publication-title: Biol Psychiatry
– volume: 114
  start-page: 2283
  year: 1991
  end-page: 2301
  ident: bib64
  article-title: Ageing and Parkinson’s disease: substantia nigra regional selectivity
  publication-title: Brain
– volume: 334
  start-page: 111
  year: 1997
  end-page: 114
  ident: bib71
  article-title: Oxygen radicals diminish dopamine transporter function in rat striatum
  publication-title: Eur J Pharmacol
– volume: 254
  start-page: 576
  year: 1991
  end-page: 578
  ident: bib228
  article-title: Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA
  publication-title: Science
– volume: 274
  start-page: 35794
  year: 1999
  end-page: 35801
  ident: bib43
  article-title: Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
  publication-title: J Biol Chem
– volume: 278
  start-page: 4990
  year: 2003
  end-page: 5000
  ident: bib97
  article-title: N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization
  publication-title: J Biol Chem
– volume: 81
  start-page: 859
  year: 2002
  end-page: 869
  ident: bib30
  article-title: PI 3-kinase regulation of dopamine uptake
  publication-title: J Neurochem
– volume: 6
  start-page: 455
  year: 2006
  end-page: 468
  ident: bib252
  article-title: A review of the use of modafinil for attention-deficit hyperactivity disorder
  publication-title: Expert Rev Neurother
– volume: 10
  start-page: 311
  year: 2000
  end-page: 320
  ident: bib245
  article-title: Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults
  publication-title: J Child Adolesc Psychopharmacol
– volume: 147
  start-page: 1
  year: 2015
  end-page: 19
  ident: bib204
  article-title: Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter
  publication-title: Drug Alcohol Depend
– volume: 120
  start-page: 35
  year: 2012
  end-page: 40
  ident: bib25
  article-title: Increased risk of Parkinson’s disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs
  publication-title: Drug Alcohol Depend
– volume: 282
  start-page: 1358
  year: 1997
  end-page: 1365
  ident: bib278
  article-title: Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes
  publication-title: J Pharmacol Exp Ther
– volume: 52
  start-page: 6768
  year: 2009
  end-page: 6781
  ident: bib27
  article-title: Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction
  publication-title: J Med Chem
– volume: 382
  start-page: 45
  year: 1999
  end-page: 49
  ident: bib282
  article-title: Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function
  publication-title: Eur J Pharmacol
– volume: 134B
  start-page: 67
  year: 2005
  end-page: 72
  ident: bib14
  article-title: Support for association between ADHD and two candidate genes: NET1 and DRD1
  publication-title: Am J Med Genet B Neuropsychiatr Genet
– volume: 339
  start-page: 1128
  year: 1992
  end-page: 1130
  ident: bib62
  article-title: Insulin resistance and cigarette smoking
  publication-title: Lancet
– volume: 102
  start-page: 3495
  year: 2005
  end-page: 3500
  ident: bib128
  article-title: Amphetamine induces dopamine efflux through a dopamine transporter channel
  publication-title: Proc Natl Acad Sci USA
– volume: 196
  start-page: 556
  year: 2008
  end-page: 561
  ident: bib82
  article-title: Interactions between eating disorders and drug abuse
  publication-title: J Nerv Ment Dis
– volume: 62
  start-page: 617
  year: 2005
  end-page: 627
  ident: bib130
  article-title: Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
  publication-title: Arch Gen Psychiatry
– volume: 285
  start-page: 107
  year: 2000
  end-page: 110
  ident: bib136
  article-title: Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography
  publication-title: Neurosci Lett
– volume: 9
  start-page: 1425
  year: 2008
  end-page: 1436
  ident: bib65
  article-title: Trafficking of vesicular neurotransmitter transporters
  publication-title: Traffic
– volume: 21
  start-page: 522
  year: 2001
  end-page: 526
  ident: bib95
  article-title: Dextroamphetamine for cocaine-dependence treatment: a double-blind randomized clinical trial
  publication-title: J Clin Psychopharmacol
– volume: 28
  start-page: 9850
  year: 2008
  end-page: 9856
  ident: bib16
  article-title: Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?
  publication-title: J Neurosci
– volume: 279
  start-page: 54380
  year: 2004
  end-page: 54386
  ident: bib122
  article-title: Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter
  publication-title: J Biol Chem
– volume: 474
  start-page: 223
  year: 2003
  end-page: 226
  ident: bib251
  article-title: Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson’s neurodegeneration
  publication-title: Eur J Pharmacol
– volume: 123
  start-page: 288
  year: 2012
  end-page: 297
  ident: bib86
  article-title: Amphetamine and methamphetamine reduce striatal dopamine transporter function without concurrent dopamine transporter relocalization
  publication-title: J Neurochem
– volume: 503
  start-page: 85
  year: 2013
  end-page: 90
  ident: bib195
  article-title: X-ray structure of dopamine transporter elucidates antidepressant mechanism
  publication-title: Nature
– volume: 42
  start-page: 383
  year: 1992
  end-page: 390
  ident: bib91
  article-title: Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
  publication-title: Mol Pharmacol
– volume: 29
  start-page: 4592
  year: 2009
  end-page: 4604
  ident: bib54
  article-title: Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3
  publication-title: J Neurosci
– volume: 32
  start-page: 217
  year: 2007
  end-page: 227
  ident: bib175
  article-title: Parkin disrupts the alpha-synuclein/dopamine transporter interaction: consequences toward dopamine-induced toxicity
  publication-title: J Mol Neurosci
– volume: 4
  start-page: 2737
  year: 1990
  end-page: 2744
  ident: bib225
  article-title: Dopamine receptors and transporters in Parkinson's disease and schizophrenia
  publication-title: FASEB J
– volume: 26
  start-page: 8195
  year: 2006
  end-page: 8205
  ident: bib235
  article-title: RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis
  publication-title: J Neurosci
– volume: 279
  start-page: 21012
  year: 2004
  end-page: 21020
  ident: bib146
  article-title: The role of N-glycosylation in function and surface trafficking of the human dopamine transporter
  publication-title: J Biol Chem
– volume: 59
  start-page: 113
  year: 2001
  end-page: 121
  ident: bib160
  article-title: Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent
  publication-title: Mol Pharmacol
– volume: 133
  start-page: 167
  year: 2015
  end-page: 173
  ident: bib276
  article-title: Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities
  publication-title: J Neurochem
– volume: 17
  start-page: 485
  year: 1997
  end-page: 488
  ident: bib96
  article-title: Replacement medication for cocaine dependence: methylphenidate
  publication-title: J Clin Psychopharmacol
– volume: 272
  start-page: 15541
  year: 1997
  end-page: 15546
  ident: bib254
  article-title: Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
  publication-title: J Biol Chem
– volume: 312
  start-page: 160
  year: 2005
  end-page: 169
  ident: bib60
  article-title: Lobeline attenuates methamphetamine-induced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum
  publication-title: J Pharmacol Exp Ther
– volume: 284
  start-page: 592
  year: 1998
  end-page: 598
  ident: bib283
  article-title: Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
  publication-title: J Pharmacol Exp Ther
– volume: 54
  start-page: 173
  year: 2004
  end-page: 182
  ident: bib262
  article-title: L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism
  publication-title: Synapse
– volume: 26
  start-page: 2127
  year: 2007
  end-page: 2136
  ident: bib143
  article-title: Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
  publication-title: EMBO J
– volume: 6
  year: 2011
  ident: bib227
  article-title: The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter
  publication-title: PLoS One
– volume: 5
  start-page: 237
  year: 1990
  end-page: 251
  ident: bib231
  article-title: A tolerance study of single and multiple dosing of the selective dopamine uptake inhibitor GBR 12909 in healthy subjects
  publication-title: Int Clin Psychopharmacol
– volume: 329
  start-page: 677
  year: 2009
  end-page: 686
  ident: bib113
  article-title: Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors
  publication-title: J Pharmacol Exp Ther
– volume: 110
  start-page: 581
  year: 2009
  end-page: 594
  ident: bib206
  article-title: The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter-2
  publication-title: J Neurochem
– volume: 17
  start-page: 957
  year: 1968
  end-page: 964
  ident: bib36
  article-title: Quantitative studies of norepinephrine uptake by synaptosomes
  publication-title: Biochem Pharmacol
– volume: 24
  start-page: 847
  year: 1975
  end-page: 852
  ident: bib110
  article-title: Studies on the distinction between uptake inhibition and release of (3H)dopamine in rat brain tissue slices
  publication-title: Biochem Pharmacol
– volume: 271
  start-page: 1444
  year: 1994
  end-page: 1452
  ident: bib205
  article-title: Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts
  publication-title: J Pharmacol Exp Ther
– volume: 4
  start-page: 1580
  year: 2013
  ident: bib210
  article-title: A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter
  publication-title: Nat Commun
– volume: 379
  start-page: 606
  year: 1996
  end-page: 612
  ident: bib92
  article-title: Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
  publication-title: Nature
– volume: 133
  start-page: 1072
  year: 1961
  end-page: 1073
  ident: bib47
  article-title: Uptake of tritium-labeled norepinephrine in brain and other tissues of cat in vitro
  publication-title: Science
– volume: 456
  start-page: 904
  year: 2008
  end-page: 909
  ident: bib129
  article-title: Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
  publication-title: Nature
– volume: 2
  year: 2004
  ident: bib131
  article-title: N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux
  publication-title: PLoS Biol
– volume: S1
  start-page: 003
  year: 2011
  ident: bib138
  article-title: Investigating methamphetamine craving using the extinction-reinstatement model in the rat
  publication-title: J Addict Res Ther
– volume: 8
  start-page: 82
  year: 2003
  end-page: 93
  ident: bib66
  article-title: Insulin, food intake, and reward
  publication-title: Semin Clin Neuropsychiatry
– volume: 42
  start-page: 423
  year: 2008
  end-page: 434
  ident: bib99
  article-title: PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity
  publication-title: Neuropeptides
– volume: 17
  start-page: 4037
  year: 1997
  end-page: 4044
  ident: bib186
  article-title: Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area
  publication-title: J Neurosci
– volume: 157
  start-page: 1619
  year: 2000
  end-page: 1628
  ident: bib279
  article-title: High vesicular monoamine transporter binding in asymptomatic bipolar I disorder: sex differences and cognitive correlates
  publication-title: Am J Psychiatry
– volume: 1
  start-page: 5
  year: 2006
  ident: bib265
  article-title: Estradiol effects on the dopamine transporter - protein levels, subcellular location, and function
  publication-title: J Mol Signal
– volume: 100
  start-page: 1387
  year: 2007
  end-page: 1396
  ident: bib274
  article-title: The vesicular monoamine transporter 2 contains trafficking signals in both its N-glycosylation and C-terminal domains
  publication-title: J Neurochem
– volume: 19
  start-page: 7699
  year: 1999
  end-page: 7710
  ident: bib166
  article-title: Membrane trafficking regulates the activity of the human dopamine transporter
  publication-title: J Neurosci
– volume: 18
  start-page: pyv024
  year: 2015
  ident: bib7
  article-title: Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents
  publication-title: Int J Neuropsychopharmacol
– volume: 18
  start-page: 8417
  year: 1998
  end-page: 8422
  ident: bib162
  article-title: Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428
  publication-title: J Neurosci
– volume: 5
  year: 2007
  ident: bib271
  article-title: Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine
  publication-title: PLoS Biol
– volume: 70
  start-page: 561
  year: 2010
  end-page: 571
  ident: bib81
  article-title: Advances in the pharmacological management of Huntington’s disease
  publication-title: Drugs
– volume: 137
  start-page: 1107
  year: 2014
  end-page: 1119
  ident: bib180
  article-title: Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood
  publication-title: Brain
– volume: 59
  start-page: 1151
  year: 2006
  end-page: 1159
  ident: bib179
  article-title: The mesolimbic dopamine reward circuit in depression
  publication-title: Biol Psychiatry
– volume: 22
  start-page: 8705
  year: 2002
  end-page: 8710
  ident: bib219
  article-title: Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors
  publication-title: J Neurosci
– volume: 83
  start-page: 53
  year: 1994
  end-page: 58
  ident: bib193
  article-title: Developmentally regulated glycosylation of dopamine transporter
  publication-title: Brain Res Dev Brain Res
– volume: 40
  start-page: 428
  year: 1996
  end-page: 439
  ident: bib272
  article-title: Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users
  publication-title: Ann Neurol
– volume: 93
  start-page: 5166
  year: 1996
  end-page: 5171
  ident: bib56
  article-title: Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter
  publication-title: Proc Natl Acad Sci USA
– volume: 449
  start-page: 71
  year: 2002
  end-page: 74
  ident: bib213
  article-title: Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine
  publication-title: Eur J Pharmacol
– volume: 68
  start-page: 11
  year: 1998
  end-page: 20
  ident: bib194
  article-title: Food deprivation decreases mRNA and activity of the rat dopamine transporter
  publication-title: Neuroendocrinology
– volume: 90
  start-page: 8861
  year: 1993
  end-page: 8865
  ident: bib144
  article-title: Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies
  publication-title: Proc Natl Acad Sci USA
– volume: 109
  start-page: 1489
  year: 2014
  end-page: 1500
  ident: bib149
  article-title: Sustained-release methylphenidate in a randomized trial of treatment of methamphetamine use disorder
  publication-title: Addiction
– volume: 964
  start-page: 107
  year: 2003
  end-page: 115
  ident: bib67
  article-title: Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
  publication-title: Brain Res
– volume: 92
  start-page: 8773
  year: 1995
  end-page: 8777
  ident: bib187
  article-title: The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei
  publication-title: Proc Natl Acad Sci USA
– volume: 298
  start-page: 1150
  year: 2001
  end-page: 1153
  ident: bib22
  article-title: Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors
  publication-title: J Pharmacol Exp Ther
– volume: 30
  start-page: 7917
  year: 2010
  end-page: 7927
  ident: bib191
  article-title: Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways
  publication-title: J Neurosci
– volume: 269
  start-page: 7231
  year: 1994
  end-page: 7237
  ident: bib196
  article-title: The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors
  publication-title: J Biol Chem
– volume: 63
  start-page: 585
  year: 2011
  end-page: 640
  ident: bib137
  article-title: SLC6 neurotransmitter transporters: structure, function, and regulation
  publication-title: Pharmacol Rev
– volume: 336
  start-page: 575
  year: 2011
  end-page: 585
  ident: bib147
  article-title: N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects
  publication-title: J Pharmacol Exp Ther
– volume: 72
  start-page: 405
  year: 2012
  end-page: 413
  ident: bib154
  article-title: R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse
  publication-title: Biol Psychiatry
– volume: 282
  start-page: 834
  year: 1997
  end-page: 838
  ident: bib72
  article-title: Rapid and reversible effects of methamphetamine on dopamine transporters
  publication-title: J Pharmacol Exp Ther
– volume: 63
  start-page: 76
  year: 2012
  end-page: 86
  ident: bib6
  article-title: You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists
  publication-title: Neuropharmacology
– volume: 61
  start-page: 1123
  year: 2011
  end-page: 1128
  ident: bib44
  article-title: Insulin signaling and addiction
  publication-title: Neuropharmacology
– volume: 77
  start-page: 754
  year: 2001
  end-page: 761
  ident: bib32
  article-title: Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein
  publication-title: J Neurochem
– volume: 185
  start-page: 327
  year: 2006
  end-page: 338
  ident: bib123
  article-title: Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers
  publication-title: Psychopharmacology (Berl)
– volume: 259
  start-page: 194
  year: 2014
  end-page: 202
  ident: bib247
  article-title: N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux
  publication-title: Neuroscience
– volume: 5
  start-page: 971
  year: 2002
  end-page: 978
  ident: bib120
  article-title: Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons
  publication-title: Nat Neurosci
– volume: 302
  start-page: 1084
  year: 2009
  end-page: 1091
  ident: bib258
  article-title: Evaluating dopamine reward pathway in ADHD: clinical implications
  publication-title: JAMA
– volume: 346
  start-page: 2
  year: 2013
  end-page: 10
  ident: bib223
  article-title: Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates
  publication-title: J Pharmacol Exp Ther
– volume: 8
  start-page: 881
  year: 2005
  end-page: 888
  ident: bib115
  article-title: Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
  publication-title: Nat Neurosci
– volume: 278
  start-page: 22168
  year: 2003
  end-page: 22174
  ident: bib152
  article-title: The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines
  publication-title: J Biol Chem
– volume: 317
  start-page: 1390
  year: 2007
  end-page: 1393
  ident: bib277
  article-title: LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
  publication-title: Science
– volume: 73
  start-page: 679
  year: 2003
  end-page: 690
  ident: bib209
  article-title: Neurotensin agonists: possible drugs for treatment of psychostimulant abuse
  publication-title: Life Sci
– volume: 2
  start-page: 311
  year: 1997
  end-page: 313
  ident: bib87
  article-title: Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism
  publication-title: Mol Psychiatry
– volume: 49
  start-page: 750
  year: 2005
  end-page: 758
  ident: bib124
  article-title: Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation
  publication-title: Neuropharmacology
– volume: 345
  start-page: 207
  year: 1998
  end-page: 211
  ident: bib50
  article-title: Inhibition of striatal dopamine transporter activity by 17beta-estradiol
  publication-title: Eur J Pharmacol
– volume: 66
  start-page: 15
  year: 2014
  end-page: 26
  ident: bib181
  article-title: Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)
  publication-title: Neurochem Int
– volume: 354
  start-page: 2132
  year: 1999
  end-page: 2133
  ident: bib52
  article-title: Dopamine transporter density in patients with attention deficit hyperactivity disorder
  publication-title: Lancet
– volume: 164
  start-page: 160
  year: 2007
  end-page: 162
  ident: bib246
  article-title: A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence
  publication-title: Am J Psychiatry
– volume: 11
  start-page: 780
  year: 2008
  end-page: 789
  ident: bib12
  article-title: The binding sites for cocaine and dopamine in the dopamine transporter overlap
  publication-title: Nat Neurosci
– volume: 34
  start-page: 8210
  year: 2014
  end-page: 8218
  ident: bib197
  article-title: Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum
  publication-title: J Neurosci
– volume: 298
  start-page: 172
  year: 2001
  end-page: 179
  ident: bib106
  article-title: Lobeline attenuates d-methamphetamine self-administration in rats
  publication-title: J Pharmacol Exp Ther
– volume: 302
  start-page: 497
  year: 2002
  end-page: 501
  ident: bib24
  article-title: A single methamphetamine administration rapidly decreases vesicular dopamine uptake
  publication-title: J Pharmacol Exp Ther
– volume: 164
  start-page: 121
  year: 2002
  end-page: 137
  ident: bib156
  article-title: Biological basis of sex differences in drug abuse: preclinical and clinical studies
  publication-title: Psychopharmacology (Berl)
– volume: 47
  start-page: 369
  year: 2014
  end-page: 375
  ident: bib141
  article-title: Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases
  publication-title: BMB Rep
– volume: 278
  start-page: 2731
  year: 2003
  end-page: 2739
  ident: bib248
  article-title: Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter
  publication-title: J Biol Chem
– volume: 8
  start-page: 73
  year: 2011
  end-page: 96
  ident: bib4
  article-title: Females are more vulnerable to drug abuse than males: evidence from preclinical studies and the role of ovarian hormones
  publication-title: Curr Top Behav Neurosci
– volume: 20
  start-page: 125
  year: 1997
  end-page: 156
  ident: bib151
  article-title: The role of vesicular transport proteins in synaptic transmission and neural degeneration
  publication-title: Annu Rev Neurosci
– volume: 65
  start-page: 634
  year: 2004
  end-page: 651
  ident: bib163
  article-title: Are mood disorders and obesity related? A review for the mental health professional
  publication-title: J Clin Psychiatry
– volume: 124
  start-page: 3107
  year: 2014
  end-page: 3120
  ident: bib104
  article-title: Missense dopamine transporter mutations associate with adult parkinsonism and ADHD
  publication-title: J Clin Invest
– volume: 7
  start-page: 223
  year: 2014
  end-page: 249
  ident: bib267
  article-title: Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants
  publication-title: Psychol Res Behav Manag
– volume: 12
  start-page: 25
  year: 1965
  end-page: 30
  ident: bib93
  article-title: Metabolism of (H3)Norepinephrine in the Rat Brain
  publication-title: J Neurochem
– volume: 10
  start-page: 286
  year: 2002
  end-page: 294
  ident: bib224
  article-title: Double-blind placebo-controlled trial of methylphenidate in the treatment of adult ADHD patients with comorbid cocaine dependence
  publication-title: Exp Clin Psychopharmacol
– volume: 102
  start-page: 16
  year: 2007
  end-page: 32
  ident: bib31
  article-title: Structural and metabolic brain changes in the striatum associated with methamphetamine abuse
  publication-title: Addiction
– volume: 26
  start-page: 903
  year: 2000
  end-page: 912
  ident: bib51
  article-title: Prevalence and correlates of diabetes in national schizophrenia samples
  publication-title: Schizophr Bull
– volume: 89
  start-page: 276
  year: 2011
  end-page: 282
  ident: bib85
  article-title: A randomized, placebo-controlled trial of sustained-release dextroamphetamine for treatment of methamphetamine addiction
  publication-title: Clin Pharmacol Ther
– volume: 89
  start-page: 11988
  year: 1992
  end-page: 11992
  ident: bib119
  article-title: Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus
  publication-title: Proc Natl Acad Sci USA
– volume: 152
  start-page: 1159
  year: 2001
  end-page: 1168
  ident: bib264
  article-title: An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles
  publication-title: J Cell Biol
– volume: 106
  start-page: 233
  year: 2010
  end-page: 236
  ident: bib263
  article-title: Modafinil does not serve as a reinforcer in cocaine abusers
  publication-title: Drug Alcohol Depend
– volume: 287
  start-page: 29702
  year: 2012
  end-page: 29712
  ident: bib79
  article-title: Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux
  publication-title: J Biol Chem
– volume: 39
  start-page: 211
  year: 2008
  end-page: 217
  ident: bib18
  article-title: Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization
  publication-title: Mol Cell Neurosci
– volume: 160
  start-page: 47
  year: 2003
  end-page: 55
  ident: bib150
  article-title: Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users
  publication-title: Am J Psychiatry
– volume: 18
  start-page: 927
  year: 1993
  end-page: 936
  ident: bib268
  article-title: A model of the sodium dependence of dopamine uptake in rat striatal synaptosomes
  publication-title: Neurochem Res
– volume: 124
  start-page: 235
  year: 2009
  end-page: 247
  ident: bib273
  article-title: Anti-relapse medications: preclinical models for drug addiction treatment
  publication-title: Pharmacol Ther
– volume: 98
  start-page: 70
  year: 2008
  end-page: 76
  ident: bib41
  article-title: Dopamine transporter levels in cocaine dependent subjects
  publication-title: Drug Alcohol Depend
– volume: 51
  start-page: 417
  year: 2006
  end-page: 429
  ident: bib75
  article-title: Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport
  publication-title: Neuron
– volume: 516
  start-page: 1
  year: 1990
  end-page: 7
  ident: bib158
  article-title: The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat
  publication-title: Brain Res
– volume: 64
  start-page: 932
  year: 2007
  end-page: 940
  ident: bib260
  article-title: Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder
  publication-title: Arch Gen Psychiatry
– volume: 1190
  start-page: 185
  year: 1994
  end-page: 187
  ident: bib171
  article-title: The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation
  publication-title: Biochim Biophys Acta
– volume: 17
  start-page: 39
  year: 2007
  end-page: 59
  ident: bib241
  article-title: Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis
  publication-title: Neuropsychol Rev
– volume: 53
  start-page: 935
  year: 2002
  end-page: 942
  ident: bib63
  article-title: Obesity-depression associations in the population
  publication-title: J Psychosom Res
– volume: 277
  start-page: 1527
  year: 1996
  end-page: 1532
  ident: bib37
  article-title: Protein kinase C activators decrease dopamine uptake into striatal synaptosomes
  publication-title: J Pharmacol Exp Ther
– volume: 34
  start-page: 1182
  year: 2007
  end-page: 1190
  ident: bib259
  article-title: Brain dopamine transporter levels in treatment and drug naïve adults with ADHD
  publication-title: Neuroimage
– volume: 15
  start-page: 916
  year: 2001
  end-page: 926
  ident: bib142
  article-title: Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
  publication-title: FASEB J
– volume: 46
  start-page: 10484
  year: 2007
  end-page: 10497
  ident: bib1
  article-title: Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching
  publication-title: Biochemistry
– volume: 24
  start-page: 7024
  year: 2004
  end-page: 7036
  ident: bib13
  article-title: Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions
  publication-title: J Neurosci
– volume: 379
  start-page: 107
  year: 1999
  end-page: 110
  ident: bib109
  article-title: Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters
  publication-title: Eur J Pharmacol
– volume: 74
  start-page: 2221
  year: 2000
  end-page: 2223
  ident: bib21
  article-title: Methamphetamine rapidly decreases vesicular dopamine uptake
  publication-title: J Neurochem
– volume: 339
  start-page: 207
  year: 2014
  end-page: 209
  ident: bib121
  article-title: Comparison of dopamine transporter decline in a patient with Parkinson’s disease and normal aging effect
  publication-title: J Neurol Sci
– volume: 146
  start-page: 30
  year: 2015
  end-page: 38
  ident: bib42
  article-title: Methamphetamine/amphetamine abuse and risk of Parkinson’s disease in Utah: a population-based assessment
  publication-title: Drug Alcohol Depend
– volume: 49
  start-page: 724
  year: 2005
  end-page: 736
  ident: bib161
  article-title: Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder
  publication-title: Neuropharmacology
– volume: 69
  start-page: 129
  year: 2014
  end-page: 176
  ident: bib118
  article-title: Monoamine transporter inhibitors and substrates as treatments for stimulant abuse
  publication-title: Adv Pharmacol
– volume: 49
  start-page: 980
  year: 2010
  end-page: 989
  ident: bib168
  article-title: Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication--Adolescent Supplement (NCS-A)
  publication-title: J Am Acad Child Adolesc Psychiatry
– volume: 75
  start-page: 406
  year: 2005
  end-page: 433
  ident: bib239
  article-title: Mechanisms of neurotransmitter release by amphetamines: a review
  publication-title: Prog Neurobiol
– volume: 98
  start-page: 10055
  year: 2001
  end-page: 10060
  ident: bib108
  article-title: Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment
  publication-title: Proc Natl Acad Sci USA
– volume: 41
  start-page: 329
  year: 2001
  end-page: 336
  ident: bib240
  article-title: Vesicular neurotransmitter transporters in Huntington’s disease: initial observations and comparison with traditional synaptic markers
  publication-title: Synapse
– volume: 35
  start-page: 217
  year: 2010
  end-page: 238
  ident: bib134
  article-title: Neurocircuitry of addiction
  publication-title: Neuropsychopharmacology
– volume: 17
  start-page: 230
  year: 2010
  end-page: 236
  ident: bib270
  article-title: Advances in the treatment of attention-deficit/hyperactivity disorder: a guide for pediatric neurologists
  publication-title: Semin Pediatr Neurol
– volume: 59
  start-page: 419
  year: 1977
  end-page: 424
  ident: bib198
  article-title: Effect of neuroleptics and other drugs on monoamine uptake by membranes of adrenal chromaffin granules
  publication-title: Br J Pharmacol
– volume: 348
  start-page: 174
  year: 2014
  end-page: 191
  ident: bib111
  article-title: Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats
  publication-title: J Pharmacol Exp Ther
– volume: 58
  start-page: 303
  year: 2008
  end-page: 313
  ident: bib207
  article-title: Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway
  publication-title: Brain Res Brain Res Rev
– volume: 315
  start-page: 397
  year: 2005
  end-page: 404
  ident: bib48
  article-title: Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-2-[bis-(4-fluorophenyl)methoxy]ethyl-4-(3-phenylpropyl)piperazine], and benztropine analogs
  publication-title: J Pharmacol Exp Ther
– volume: 10
  start-page: 54
  year: 2011
  end-page: 62
  ident: bib139
  article-title: Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study
  publication-title: Lancet Neurol
– volume: 101
  start-page: 34
  year: 2009
  end-page: 41
  ident: bib174
  article-title: Effects of oral methamphetamine on cocaine use: a randomized, double-blind, placebo-controlled trial
  publication-title: Drug Alcohol Depend
– volume: 49
  start-page: 7
  year: 1997
  end-page: 14
  ident: bib242
  article-title: Murine vesicular monoamine transporter 2: molecular cloning and genomic structure
  publication-title: Brain Res Mol Brain Res
– volume: 323
  start-page: 738
  year: 2007
  end-page: 745
  ident: bib261
  article-title: Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles
  publication-title: J Pharmacol Exp Ther
– volume: 70
  start-page: 9
  year: 2006
  end-page: 15
  ident: bib117
  article-title: The discovery of dopamine deficiency in the parkinsonian brain
  publication-title: J Neural Transm Suppl
– volume: 14
  start-page: 469
  year: 2011
  end-page: 477
  ident: bib40
  article-title: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT
  publication-title: Nat Neurosci
– volume: 31
  start-page: 327
  year: 1988
  end-page: 335
  ident: bib183
  article-title: Effects of cocaine on release and uptake of dopamine in vivo: differentiation by mathematical modeling
  publication-title: Pharmacol Biochem Behav
– volume: 74
  start-page: 2217
  year: 2000
  end-page: 2220
  ident: bib114
  article-title: Analysis of VMAT2 binding after methamphetamine or MPTP treatment: disparity between homogenates and vesicle preparations
  publication-title: J Neurochem
– volume: 280
  start-page: 35617
  year: 2005
  end-page: 35624
  ident: bib173
  article-title: Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C
  publication-title: J Biol Chem
– volume: 6
  year: 2011
  ident: bib222
  article-title: The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors
  publication-title: PLoS One
– volume: 17
  start-page: 960
  year: 1997
  end-page: 974
  ident: bib232
  article-title: Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants
  publication-title: J Neurosci
– volume: 295
  start-page: 1077
  year: 2000
  end-page: 1085
  ident: bib169
  article-title: Methamphetamine-induced rapid decrease in dopamine transporter function: role of dopamine and hyperthermia
  publication-title: J Pharmacol Exp Ther
– volume: 148
  start-page: 1
  year: 1965
  end-page: 8
  ident: bib145
  article-title: Elucidation of the rate-limiting step in norepinephrine biosynthesis in the perfused guinea-pig heart
  publication-title: J Pharmacol Exp Ther
– volume: 286
  start-page: 5175
  year: 2011
  end-page: 5186
  ident: bib78
  article-title: Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation
  publication-title: J Biol Chem
– volume: 67
  start-page: 593
  year: 1996
  end-page: 600
  ident: bib10
  article-title: Modification of dopamine transporter function: effect of reactive oxygen species and dopamine
  publication-title: J Neurochem
– volume: 69
  start-page: 628
  year: 2011
  end-page: 649
  ident: bib237
  article-title: How addictive drugs disrupt presynaptic dopamine neurotransmission
  publication-title: Neuron
– volume: 89
  start-page: 10993
  year: 1992
  end-page: 10997
  ident: bib55
  article-title: Expression cloning of a reserpine-sensitive vesicular monoamine transporter
  publication-title: Proc Natl Acad Sci USA
– volume: 592
  start-page: 109
  year: 2008
  end-page: 115
  ident: bib226
  article-title: Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats
  publication-title: Eur J Pharmacol
– volume: 237
  start-page: 1219
  year: 1987
  end-page: 1223
  ident: bib215
  article-title: Cocaine receptors on dopamine transporters are related to self-administration of cocaine
  publication-title: Science
– volume: 111
  start-page: E4779
  year: 2014
  end-page: E4788
  ident: bib167
  article-title: The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants
  publication-title: Proc Natl Acad Sci USA
– volume: 3
  start-page: 1447
  year: 2013
  ident: bib190
  article-title: The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry
  publication-title: Sci Rep
– volume: 47
  start-page: 681
  year: 2007
  end-page: 698
  ident: bib73
  article-title: New insights into the mechanism of action of amphetamines
  publication-title: Annu Rev Pharmacol Toxicol
– volume: 330
  start-page: 802
  year: 2009
  end-page: 809
  ident: bib243
  article-title: Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity
  publication-title: J Pharmacol Exp Ther
– volume: 5
  start-page: 275
  year: 2000
  end-page: 282
  ident: bib98
  article-title: Systematic screening for DNA sequence variation in the coding region of the human dopamine transporter gene (DAT1)
  publication-title: Mol Psychiatry
– volume: 296
  start-page: 762
  year: 2001
  end-page: 767
  ident: bib23
  article-title: Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants
  publication-title: J Pharmacol Exp Ther
– volume: 24
  start-page: 3436
  year: 2004
  end-page: 3443
  ident: bib9
  article-title: Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine- and hyperthermia-associated mechanism
  publication-title: J Neurosci
– volume: 27
  start-page: 270
  year: 2004
  end-page: 277
  ident: bib39
  article-title: DAncing past the DAT at a DA synapse
  publication-title: Trends Neurosci
– volume: 119
  start-page: 1595
  year: 2009
  end-page: 1603
  ident: bib140
  article-title: Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia
  publication-title: J Clin Invest
– volume: 276
  start-page: 29012
  year: 2001
  end-page: 29018
  ident: bib203
  article-title: The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter
  publication-title: J Biol Chem
– volume: 46
  start-page: 343
  year: 1997
  end-page: 346
  ident: bib17
  article-title: Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain
  publication-title: Brain Res Mol Brain Res
– volume: 18
  start-page: 313
  year: 2007
  end-page: 323
  ident: bib172
  article-title: Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter
  publication-title: Mol Biol Cell
– volume: 37
  start-page: 68
  year: 1996
  end-page: 73
  ident: bib176
  article-title: Diabetes mellitus in schizophrenic patients
  publication-title: Compr Psychiatry
– volume: 32
  start-page: 5385
  year: 2012
  end-page: 5397
  ident: bib218
  article-title: Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation
  publication-title: J Neurosci
– volume: 290
  start-page: 1545
  year: 2002
  end-page: 1550
  ident: bib45
  article-title: Cocaine increases dopamine uptake and cell surface expression of dopamine transporters
  publication-title: Biochem Biophys Res Commun
– volume: 278
  start-page: 28274
  year: 2003
  end-page: 28283
  ident: bib233
  article-title: Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy
  publication-title: J Biol Chem
– volume: 6
  start-page: 157
  year: 2005
  end-page: 170
  ident: bib234
  article-title: Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism
  publication-title: Traffic
– volume: 47
  start-page: 256
  year: 2004
  end-page: 273
  ident: bib8
  article-title: Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats
  publication-title: Neuropharmacology
– volume: 158
  start-page: 377
  year: 2001
  end-page: 382
  ident: bib257
  article-title: Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers
  publication-title: Am J Psychiatry
– volume: 341
  start-page: 251
  year: 2012
  end-page: 262
  ident: bib216
  article-title: Studies of the biogenic amine transporters. 14. Identification of low-efficacy “partial” substrates for the biogenic amine transporters
  publication-title: J Pharmacol Exp Ther
– volume: 44
  start-page: 73
  year: 2013
  end-page: 80
  ident: bib256
  article-title: The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens
  publication-title: Prog Neuropsychopharmacol Biol Psychiatry
– volume: 20
  start-page: 7297
  year: 2000
  end-page: 7306
  ident: bib200
  article-title: Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size
  publication-title: J Neurosci
– volume: 304
  start-page: 1181
  year: 2003
  end-page: 1187
  ident: bib220
  article-title: Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits
  publication-title: J Pharmacol Exp Ther
– volume: 94
  start-page: 1402
  year: 2005
  end-page: 1410
  ident: bib192
  article-title: Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine
  publication-title: J Neurochem
– volume: 4
  year: 2014
  ident: bib19
  article-title: SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking
  publication-title: Transl Psychiatry
– volume: 285
  start-page: 1957
  year: 2010
  end-page: 1966
  ident: bib29
  article-title: A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles
  publication-title: J Biol Chem
– volume: 30
  start-page: 121
  year: 2001
  end-page: 134
  ident: bib249
  article-title: Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
  publication-title: Neuron
– volume: 406
  start-page: 1
  year: 2000
  end-page: 13
  ident: bib70
  article-title: Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
  publication-title: Eur J Pharmacol
– volume: 277
  start-page: 25178
  year: 2002
  end-page: 25186
  ident: bib77
  article-title: Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
  publication-title: J Biol Chem
– volume: 57
  start-page: 640
  year: 2009
  end-page: 652
  ident: bib217
  article-title: Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task
  publication-title: Neuropharmacology
– volume: 479
  start-page: 93
  year: 2003
  end-page: 106
  ident: bib53
  article-title: Dopamine transporter as target for drug development of cocaine dependence medications
  publication-title: Eur J Pharmacol
– volume: 346
  start-page: 173
  year: 2013
  end-page: 181
  ident: bib105
  article-title: Response of neurotensin basal ganglia systems during extinction of methamphetamine self-administration in rat
  publication-title: J Pharmacol Exp Ther
– volume: 288
  start-page: 27534
  year: 2013
  end-page: 27544
  ident: bib211
  article-title: Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release
  publication-title: J Biol Chem
– volume: 108
  start-page: 1575
  year: 2009
  end-page: 1584
  ident: bib208
  article-title: Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: rat dorsal striatum versus nucleus accumbens
  publication-title: J Neurochem
– volume: 21
  start-page: 1413
  year: 2001
  end-page: 1419
  ident: bib284
  article-title: Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model
  publication-title: J Neurosci
– volume: 169
  start-page: 55
  year: 2012
  end-page: 63
  ident: bib178
  article-title: In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in cocaine abusers
  publication-title: Am J Psychiatry
– volume: 25
  start-page: 1889
  year: 2005
  end-page: 1893
  ident: bib49
  article-title: Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine
  publication-title: J Neurosci
– volume: 46
  start-page: 148
  year: 2011
  end-page: 158
  ident: bib202
  article-title: Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons
  publication-title: Mol Cell Neurosci
– volume: 220
  start-page: 9
  year: 1999
  end-page: 19
  ident: bib266
  article-title: Membrane-initiated steroid actions and the proteins that mediate them
  publication-title: Proc Soc Exp Biol Med
– volume: 48
  start-page: 1067
  year: 2009
  end-page: 1076
  ident: bib94
  article-title: Proline-directed phosphorylation of the dopamine transporter N-terminal domain
  publication-title: Biochemistry
– volume: 295
  start-page: 149
  year: 1991
  end-page: 154
  ident: bib90
  article-title: Cloning and functional characterization of a cocaine-sensitive dopamine transporter
  publication-title: FEBS Lett
– volume: 67
  start-page: 59
  year: 2010
  end-page: 68
  ident: bib177
  article-title: Brain serotonin and dopamine transporter bindings in adults with high-functioning autism
  publication-title: Arch Gen Psychiatry
– volume: 7
  start-page: E847
  year: 2005
  end-page: E851
  ident: bib212
  article-title: Role of monoamine transporters in mediating psychostimulant effects
  publication-title: AAPS J
– volume: 71
  start-page: 679
  year: 2009
  end-page: 685
  ident: bib34
  article-title: Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study
  publication-title: Clin Endocrinol (Oxf)
– volume: 55
  start-page: 131
  year: 1993
  end-page: 141
  ident: bib69
  article-title: Electrical stimulation of reward sites in the ventral tegmental area increases dopamine transmission in the nucleus accumbens of the rat
  publication-title: Behav Brain Res
– volume: 63
  start-page: 824
  year: 2006
  end-page: 830
  ident: bib229
  article-title: Association between obesity and psychiatric disorders in the US adult population
  publication-title: Arch Gen Psychiatry
– volume: 368
  start-page: 543
  year: 2013
  end-page: 550
  ident: bib214
  article-title: Brain dopamine-serotonin vesicular transport disease and its treatment
  publication-title: N Engl J Med
– volume: 95
  start-page: 4029
  year: 1998
  end-page: 4034
  ident: bib126
  article-title: Profound neuronal plasticity in response to inactivation of the dopamine transporter
  publication-title: Proc Natl Acad Sci USA
– volume: 69
  start-page: 71
  year: 2014
  end-page: 106
  ident: bib182
  article-title: The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse
  publication-title: Adv Pharmacol
– volume: 73
  start-page: 813
  year: 2008
  end-page: 823
  ident: bib153
  article-title: Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors
  publication-title: Mol Pharmacol
– volume: 36
  start-page: 359
  year: 2011
  end-page: 360
  ident: bib189
  article-title: Insulin regulation of monoamine signaling: pathway to obesity
  publication-title: Neuropsychopharmacology
– volume: 70
  start-page: 185
  year: 2013
  end-page: 198
  ident: bib107
  article-title: Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects
  publication-title: JAMA Psychiatry
– volume: 1184
  start-page: 188
  year: 2010
  end-page: 195
  ident: bib101
  article-title: The progression of pathology in Parkinson’s disease
  publication-title: Ann N Y Acad Sci
– volume: 64
  start-page: 1819
  year: 1995
  end-page: 1825
  ident: bib89
  article-title: Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine
  publication-title: J Neurochem
– volume: 60
  start-page: 527
  year: 1993
  end-page: 535
  ident: bib238
  article-title: Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons
  publication-title: J Neurochem
– volume: 15
  start-page: 733
  year: 1999
  end-page: 798
  ident: bib103
  article-title: Synaptic vesicle biogenesis
  publication-title: Annu Rev Cell Dev Biol
– volume: 1321
  start-page: 51
  year: 2010
  end-page: 59
  ident: bib33
  article-title: The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study
  publication-title: Brain Res
– volume: 115
  start-page: 325
  year: 2010
  end-page: 332
  ident: bib35
  article-title: Methamphetamine alters vesicular monoamine transporter-2 function and potassium-stimulated dopamine release
  publication-title: J Neurochem
– volume: 57
  start-page: 253
  year: 2009
  end-page: 289
  ident: bib244
  article-title: Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors
  publication-title: Adv Pharmacol
– volume: 85
  start-page: 351
  year: 2007
  end-page: 363
  ident: bib80
  article-title: RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport
  publication-title: J Neurosci Res
– volume: 29
  start-page: 6794
  year: 2009
  end-page: 6808
  ident: bib59
  article-title: Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs
  publication-title: J Neurosci
– volume: 97
  start-page: 6850
  year: 2000
  end-page: 6855
  ident: bib221
  article-title: Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism
  publication-title: Proc Natl Acad Sci USA
– volume: 86
  start-page: 237
  year: 2001
  end-page: 247
  ident: bib83
  article-title: Imaging the vesicular monoamine transporter
  publication-title: Adv Neurol
– volume: 16
  start-page: 436
  year: 1996
  end-page: 447
  ident: bib188
  article-title: The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons
  publication-title: J Neurosci
– volume: 105
  start-page: 1683
  year: 2008
  end-page: 1699
  ident: bib76
  article-title: Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
  publication-title: J Neurochem
– volume: 16
  start-page: 4135
  year: 1996
  end-page: 4145
  ident: bib184
  article-title: Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: potential sites for somatodendritic storage and release of dopamine
  publication-title: J Neurosci
– volume: 26
  start-page: 1198
  year: 2006
  end-page: 1212
  ident: bib15
  article-title: Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease
  publication-title: J Cereb Blood Flow Metab
– volume: 73
  start-page: 2406
  year: 1999
  end-page: 2414
  ident: bib127
  article-title: Dopamine neuronal transport kinetics and effects of amphetamine
  publication-title: J Neurochem
– volume: 276
  start-page: 2045
  year: 1997
  end-page: 2047
  ident: bib199
  article-title: Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
  publication-title: Science
– volume: 285
  start-page: 27289
  year: 2010
  end-page: 27301
  ident: bib57
  article-title: Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons
  publication-title: J Biol Chem
– volume: 31
  start-page: 983
  year: 1982
  end-page: 992
  ident: bib148
  article-title: Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine
  publication-title: Biochem Pharmacol
– volume: 61
  start-page: 764
  year: 1993
  end-page: 767
  ident: bib165
  article-title: D2 receptors may modulate the function of the striatal transporter for dopamine: kinetic evidence from studies in vitro and in vivo
  publication-title: J Neurochem
– volume: 20
  start-page: 424
  year: 1999
  end-page: 429
  ident: bib170
  article-title: Dopamine transporters and neuronal injury
  publication-title: Trends Pharmacol Sci
– volume: 339
  start-page: 662
  year: 2011
  end-page: 677
  ident: bib112
  article-title: Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors
  publication-title: J Pharmacol Exp Ther
– volume: 285
  start-page: 32616
  year: 2010
  end-page: 32626
  ident: bib116
  article-title: Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding
  publication-title: J Biol Chem
– volume: 658
  start-page: 156
  year: 2011
  end-page: 159
  ident: bib164
  article-title: Eating high-fat chow enhances sensitization to the effects of methamphetamine on locomotion in rats
  publication-title: Eur J Pharmacol
– volume: 26
  start-page: 194
  year: 1997
  end-page: 198
  ident: bib185
  article-title: Vesicular monoamine transporter-2: immunogold localization in striatal axons and terminals
  publication-title: Synapse
– volume: 215
  start-page: 53
  year: 1996
  end-page: 56
  ident: bib74
  article-title: Amphetamine releases dopamine from synaptic vesicles by dual mechanisms
  publication-title: Neurosci Lett
– volume: 13
  start-page: 362
  year: 2013
  ident: bib3
  article-title: Vesicular integrity in Parkinson’s disease
  publication-title: Curr Neurol Neurosci Rep
– volume: 29
  start-page: 3328
  year: 2009
  end-page: 3336
  ident: bib84
  article-title: Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy
  publication-title: J Neurosci
– volume: 81
  start-page: 1035
  year: 2002
  end-page: 1042
  ident: bib275
  article-title: D(3) receptor ligands modulate extracellular dopamine clearance in the nucleus accumbens
  publication-title: J Neurochem
– volume: 113
  start-page: 27
  year: 2010
  end-page: 41
  ident: bib58
  article-title: Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges
  publication-title: J Neurochem
– volume: 287
  start-page: 12293
  year: 2012
  end-page: 12308
  ident: bib157
  article-title: Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway
  publication-title: J Biol Chem
– volume: 8
  start-page: E196
  year: 2006
  end-page: E203
  ident: bib28
  article-title: Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse
  publication-title: AAPS J
– volume: 69
  start-page: 803
  year: 2011
  end-page: 810
  ident: bib46
  article-title: Age-specific progression of nigrostriatal dysfunction in Parkinson’s disease
  publication-title: Ann Neurol
– volume: 81
  start-page: 292
  year: 2002
  end-page: 300
  ident: bib159
  article-title: Dopamine transport function is elevated in cocaine users
  publication-title: J Neurochem
– volume: 20
  start-page: S35
  year: 2014
  end-page: S38
  ident: bib236
  article-title: Genetics of Parkinson’s disease: the yield
  publication-title: Parkinsonism Relat Disord
– volume: 280
  start-page: 40442
  year: 2005
  end-page: 40449
  ident: bib281
  article-title: Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms
  publication-title: J Biol Chem
– volume: 271
  start-page: 21672
  year: 1996
  end-page: 21680
  ident: bib255
  article-title: Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis
  publication-title: J Biol Chem
– volume: 8
  year: 2013
  ident: bib38
  article-title: Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine
  publication-title: PLoS One
– volume: 272
  start-page: 6752
  year: 1997
  end-page: 6759
  ident: bib135
  article-title: Phosphorylation of a vesicular monoamine transporter by casein kinase II
  publication-title: J Biol Chem
– volume: 504
  start-page: 27
  year: 2004
  end-page: 32
  ident: bib250
  article-title: Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein
  publication-title: Eur J Pharmacol
– volume: 10
  start-page: 582
  year: 2014
  end-page: 589
  ident: bib102
  article-title: PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein
  publication-title: Nat Chem Biol
– volume: 34
  start-page: 489
  year: 2013
  end-page: 496
  ident: bib253
  article-title: Mechanisms of dopamine transporter regulation in normal and disease states
  publication-title: Trends Pharmacol Sci
– volume: 34
  start-page: 197
  year: 2013
  end-page: 219
  ident: bib201
  article-title: SLC6 transporters: structure, function, regulation, disease association and therapeutics
  publication-title: Mol Aspects Med
– volume: 62
  start-page: 1872
  year: 2004
  end-page: 1874
  ident: bib5
  article-title: Infantile Parkinsonism-dystonia and elevated dopamine metabolites in CSF
  publication-title: Neurology
– volume: 256
  start-page: 6541
  year: 1981
  end-page: 6543
  ident: bib133
  article-title: Amine transport in chromaffin granule ghosts. pH dependence implies cationic form is translocated
  publication-title: J Biol Chem
– volume: 4
  start-page: 797
  year: 1965
  end-page: 807
  ident: bib230
  article-title: The Storage of Norepinephrine and Some of Its Derivatives in Brain Synaptosomes
  publication-title: Life Sci
– volume: 20
  start-page: 163
  year: 1996
  end-page: 168
  ident: bib269
  article-title: Substance use among women with eating disorders
  publication-title: Int J Eat Disord
– volume: 24
  start-page: 197
  year: 2003
  end-page: 211
  ident: bib20
  article-title: Staging of brain pathology related to sporadic Parkinson’s disease
  publication-title: Neurobiol Aging
– volume: 62
  start-page: 155
  year: 2010
  end-page: 198
  ident: bib88
  article-title: Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines
  publication-title: Pharmacol Rev
– volume: 335
  start-page: 207
  year: 2010
  end-page: 212
  ident: bib100
  article-title: Methamphetamine-induced dopamine transporter complex formation and dopaminergic deficits: the role of D2 receptor activation
  publication-title: J Pharmacol Exp Ther
– volume: 254
  start-page: 578
  year: 1991
  end-page: 579
  ident: bib132
  article-title: Cloning and expression of a cocaine-sensitive rat dopamine transporter
  publication-title: Science
– volume: 36
  start-page: 494
  year: 2009
  end-page: 508
  ident: bib2
  article-title: Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson’s disease
  publication-title: Neurobiol Dis
– volume: 366
  start-page: 344
  year: 1993
  end-page: 347
  ident: bib26
  article-title: Dopamine D1 receptors facilitate transmitter release
  publication-title: Nature
– volume: 105
  start-page: 146
  year: 2010
  end-page: 154
  ident: bib155
  article-title: Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence
  publication-title: Addiction
– volume: 644
  start-page: 331
  year: 1994
  end-page: 334
  ident: bib68
  article-title: Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra
  publication-title: Brain Res
– volume: 73
  start-page: 89
  year: 2014
  end-page: 97
  ident: bib11
  article-title: The vesicular monoamine transporter 2: an underexplored pharmacological target
  publication-title: Neurochem Int
– volume: 41
  start-page: 329
  year: 2001
  ident: 10.1124/pr.114.010397_bib240
  article-title: Vesicular neurotransmitter transporters in Huntington’s disease: initial observations and comparison with traditional synaptic markers
  publication-title: Synapse
  doi: 10.1002/syn.1089
– volume: 59
  start-page: 1151
  year: 2006
  ident: 10.1124/pr.114.010397_bib179
  article-title: The mesolimbic dopamine reward circuit in depression
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2005.09.018
– volume: 34
  start-page: 489
  year: 2013
  ident: 10.1124/pr.114.010397_bib253
  article-title: Mechanisms of dopamine transporter regulation in normal and disease states
  publication-title: Trends Pharmacol Sci
  doi: 10.1016/j.tips.2013.07.005
– volume: 287
  start-page: 29702
  year: 2012
  ident: 10.1124/pr.114.010397_bib79
  article-title: Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M112.367706
– volume: 285
  start-page: 107
  year: 2000
  ident: 10.1124/pr.114.010397_bib136
  article-title: Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography
  publication-title: Neurosci Lett
  doi: 10.1016/S0304-3940(00)01040-5
– volume: 4
  start-page: 797
  year: 1965
  ident: 10.1124/pr.114.010397_bib230
  article-title: The Storage of Norepinephrine and Some of Its Derivatives in Brain Synaptosomes
  publication-title: Life Sci
  doi: 10.1016/0024-3205(65)90312-7
– volume: 164
  start-page: 160
  year: 2007
  ident: 10.1124/pr.114.010397_bib246
  article-title: A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence
  publication-title: Am J Psychiatry
  doi: 10.1176/ajp.2007.164.1.160
– volume: 24
  start-page: 3436
  year: 2004
  ident: 10.1124/pr.114.010397_bib9
  article-title: Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine- and hyperthermia-associated mechanism
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.0387-04.2004
– volume: 3
  start-page: 1447
  year: 2013
  ident: 10.1124/pr.114.010397_bib190
  article-title: The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry
  publication-title: Sci Rep
  doi: 10.1038/srep01447
– volume: 158
  start-page: 377
  year: 2001
  ident: 10.1124/pr.114.010397_bib257
  article-title: Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.158.3.377
– volume: 1190
  start-page: 185
  year: 1994
  ident: 10.1124/pr.114.010397_bib171
  article-title: The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(94)90051-5
– volume: 46
  start-page: 343
  year: 1997
  ident: 10.1124/pr.114.010397_bib17
  article-title: Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/S0169-328X(97)00082-X
– volume: 366
  start-page: 344
  year: 1993
  ident: 10.1124/pr.114.010397_bib26
  article-title: Dopamine D1 receptors facilitate transmitter release
  publication-title: Nature
  doi: 10.1038/366344a0
– volume: 42
  start-page: 383
  year: 1992
  ident: 10.1124/pr.114.010397_bib91
  article-title: Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
  publication-title: Mol Pharmacol
  doi: 10.1016/S0026-895X(25)08925-4
– volume: 278
  start-page: 22168
  year: 2003
  ident: 10.1124/pr.114.010397_bib152
  article-title: The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M301845200
– volume: 40
  start-page: 428
  year: 1996
  ident: 10.1124/pr.114.010397_bib272
  article-title: Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users
  publication-title: Ann Neurol
  doi: 10.1002/ana.410400312
– volume: 6
  year: 2011
  ident: 10.1124/pr.114.010397_bib227
  article-title: The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0016350
– volume: 29
  start-page: 4592
  year: 2009
  ident: 10.1124/pr.114.010397_bib54
  article-title: Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.4559-08.2009
– volume: 31
  start-page: 983
  year: 1982
  ident: 10.1124/pr.114.010397_bib148
  article-title: Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine
  publication-title: Biochem Pharmacol
  doi: 10.1016/0006-2952(82)90332-X
– volume: 26
  start-page: 194
  year: 1997
  ident: 10.1124/pr.114.010397_bib185
  article-title: Vesicular monoamine transporter-2: immunogold localization in striatal axons and terminals
  publication-title: Synapse
  doi: 10.1002/(SICI)1098-2396(199706)26:2<194::AID-SYN10>3.0.CO;2-Y
– volume: 254
  start-page: 578
  year: 1991
  ident: 10.1124/pr.114.010397_bib132
  article-title: Cloning and expression of a cocaine-sensitive rat dopamine transporter
  publication-title: Science
  doi: 10.1126/science.1948035
– volume: 516
  start-page: 1
  year: 1990
  ident: 10.1124/pr.114.010397_bib158
  article-title: The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat
  publication-title: Brain Res
  doi: 10.1016/0006-8993(90)90889-J
– volume: 269
  start-page: 7231
  year: 1994
  ident: 10.1124/pr.114.010397_bib196
  article-title: The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(17)37272-1
– volume: 382
  start-page: 45
  year: 1999
  ident: 10.1124/pr.114.010397_bib282
  article-title: Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(99)00588-9
– volume: 302
  start-page: 497
  year: 2002
  ident: 10.1124/pr.114.010397_bib24
  article-title: A single methamphetamine administration rapidly decreases vesicular dopamine uptake
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.302.2.497
– volume: 449
  start-page: 71
  year: 2002
  ident: 10.1124/pr.114.010397_bib213
  article-title: Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(02)01985-4
– volume: 379
  start-page: 107
  year: 1999
  ident: 10.1124/pr.114.010397_bib109
  article-title: Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(99)00487-2
– volume: 277
  start-page: 1527
  year: 1996
  ident: 10.1124/pr.114.010397_bib37
  article-title: Protein kinase C activators decrease dopamine uptake into striatal synaptosomes
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(25)13104-2
– volume: 34
  start-page: 1182
  year: 2007
  ident: 10.1124/pr.114.010397_bib259
  article-title: Brain dopamine transporter levels in treatment and drug naïve adults with ADHD
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2006.10.014
– volume: 24
  start-page: 197
  year: 2003
  ident: 10.1124/pr.114.010397_bib20
  article-title: Staging of brain pathology related to sporadic Parkinson’s disease
  publication-title: Neurobiol Aging
  doi: 10.1016/S0197-4580(02)00065-9
– volume: 70
  start-page: 561
  year: 2010
  ident: 10.1124/pr.114.010397_bib81
  article-title: Advances in the pharmacological management of Huntington’s disease
  publication-title: Drugs
  doi: 10.2165/11534430-000000000-00000
– volume: 157
  start-page: 1619
  year: 2000
  ident: 10.1124/pr.114.010397_bib279
  article-title: High vesicular monoamine transporter binding in asymptomatic bipolar I disorder: sex differences and cognitive correlates
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.157.10.1619
– volume: 196
  start-page: 556
  year: 2008
  ident: 10.1124/pr.114.010397_bib82
  article-title: Interactions between eating disorders and drug abuse
  publication-title: J Nerv Ment Dis
  doi: 10.1097/NMD.0b013e31817d0153
– volume: 69
  start-page: 129
  year: 2014
  ident: 10.1124/pr.114.010397_bib118
  article-title: Monoamine transporter inhibitors and substrates as treatments for stimulant abuse
  publication-title: Adv Pharmacol
  doi: 10.1016/B978-0-12-420118-7.00004-4
– volume: 47
  start-page: 681
  year: 2007
  ident: 10.1124/pr.114.010397_bib73
  article-title: New insights into the mechanism of action of amphetamines
  publication-title: Annu Rev Pharmacol Toxicol
  doi: 10.1146/annurev.pharmtox.47.120505.105140
– volume: 89
  start-page: 11988
  year: 1992
  ident: 10.1124/pr.114.010397_bib119
  article-title: Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.89.24.11988
– volume: 70
  start-page: 9
  year: 2006
  ident: 10.1124/pr.114.010397_bib117
  article-title: The discovery of dopamine deficiency in the parkinsonian brain
  publication-title: J Neural Transm Suppl
– volume: 7
  start-page: 223
  year: 2014
  ident: 10.1124/pr.114.010397_bib267
  article-title: Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants
  publication-title: Psychol Res Behav Manag
  doi: 10.2147/PRBM.S47013
– volume: 282
  start-page: 834
  year: 1997
  ident: 10.1124/pr.114.010397_bib72
  article-title: Rapid and reversible effects of methamphetamine on dopamine transporters
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)36858-2
– volume: 298
  start-page: 1150
  year: 2001
  ident: 10.1124/pr.114.010397_bib22
  article-title: Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)29485-4
– volume: 147
  start-page: 1
  year: 2015
  ident: 10.1124/pr.114.010397_bib204
  article-title: Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2014.12.005
– volume: 86
  start-page: 237
  year: 2001
  ident: 10.1124/pr.114.010397_bib83
  article-title: Imaging the vesicular monoamine transporter
  publication-title: Adv Neurol
– volume: 146
  start-page: 30
  year: 2015
  ident: 10.1124/pr.114.010397_bib42
  article-title: Methamphetamine/amphetamine abuse and risk of Parkinson’s disease in Utah: a population-based assessment
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2014.10.027
– volume: 279
  start-page: 21012
  year: 2004
  ident: 10.1124/pr.114.010397_bib146
  article-title: The role of N-glycosylation in function and surface trafficking of the human dopamine transporter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M311972200
– volume: 285
  start-page: 1957
  year: 2010
  ident: 10.1124/pr.114.010397_bib29
  article-title: A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M109.054510
– volume: 34
  start-page: 197
  year: 2013
  ident: 10.1124/pr.114.010397_bib201
  article-title: SLC6 transporters: structure, function, regulation, disease association and therapeutics
  publication-title: Mol Aspects Med
  doi: 10.1016/j.mam.2012.07.002
– volume: 276
  start-page: 29012
  year: 2001
  ident: 10.1124/pr.114.010397_bib203
  article-title: The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M011785200
– volume: 68
  start-page: 11
  year: 1998
  ident: 10.1124/pr.114.010397_bib194
  article-title: Food deprivation decreases mRNA and activity of the rat dopamine transporter
  publication-title: Neuroendocrinology
  doi: 10.1159/000054345
– volume: 32
  start-page: 217
  year: 2007
  ident: 10.1124/pr.114.010397_bib175
  article-title: Parkin disrupts the alpha-synuclein/dopamine transporter interaction: consequences toward dopamine-induced toxicity
  publication-title: J Mol Neurosci
  doi: 10.1007/s12031-007-0037-0
– volume: 73
  start-page: 89
  year: 2014
  ident: 10.1124/pr.114.010397_bib11
  article-title: The vesicular monoamine transporter 2: an underexplored pharmacological target
  publication-title: Neurochem Int
  doi: 10.1016/j.neuint.2013.12.003
– volume: 341
  start-page: 251
  year: 2012
  ident: 10.1124/pr.114.010397_bib216
  article-title: Studies of the biogenic amine transporters. 14. Identification of low-efficacy “partial” substrates for the biogenic amine transporters
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.111.188946
– volume: 134B
  start-page: 67
  year: 2005
  ident: 10.1124/pr.114.010397_bib14
  article-title: Support for association between ADHD and two candidate genes: NET1 and DRD1
  publication-title: Am J Med Genet B Neuropsychiatr Genet
  doi: 10.1002/ajmg.b.30142
– volume: 109
  start-page: 1489
  year: 2014
  ident: 10.1124/pr.114.010397_bib149
  article-title: Sustained-release methylphenidate in a randomized trial of treatment of methamphetamine use disorder
  publication-title: Addiction
  doi: 10.1111/add.12608
– volume: 66
  start-page: 15
  year: 2014
  ident: 10.1124/pr.114.010397_bib181
  article-title: Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)
  publication-title: Neurochem Int
  doi: 10.1016/j.neuint.2014.01.002
– volume: 123
  start-page: 288
  year: 2012
  ident: 10.1124/pr.114.010397_bib86
  article-title: Amphetamine and methamphetamine reduce striatal dopamine transporter function without concurrent dopamine transporter relocalization
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2012.07875.x
– volume: 29
  start-page: 3328
  year: 2009
  ident: 10.1124/pr.114.010397_bib84
  article-title: Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5386-08.2009
– volume: 288
  start-page: 27534
  year: 2013
  ident: 10.1124/pr.114.010397_bib211
  article-title: Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M112.441295
– volume: 73
  start-page: 2406
  year: 1999
  ident: 10.1124/pr.114.010397_bib127
  article-title: Dopamine neuronal transport kinetics and effects of amphetamine
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.1999.0732406.x
– volume: 346
  start-page: 173
  year: 2013
  ident: 10.1124/pr.114.010397_bib105
  article-title: Response of neurotensin basal ganglia systems during extinction of methamphetamine self-administration in rat
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.113.205310
– volume: 115
  start-page: 325
  year: 2010
  ident: 10.1124/pr.114.010397_bib35
  article-title: Methamphetamine alters vesicular monoamine transporter-2 function and potassium-stimulated dopamine release
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2010.06922.x
– volume: 8
  start-page: 82
  year: 2003
  ident: 10.1124/pr.114.010397_bib66
  article-title: Insulin, food intake, and reward
  publication-title: Semin Clin Neuropsychiatry
  doi: 10.1053/scnp.2003.50012
– volume: 90
  start-page: 8861
  year: 1993
  ident: 10.1124/pr.114.010397_bib144
  article-title: Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.90.19.8861
– volume: 290
  start-page: 1545
  year: 2002
  ident: 10.1124/pr.114.010397_bib45
  article-title: Cocaine increases dopamine uptake and cell surface expression of dopamine transporters
  publication-title: Biochem Biophys Res Commun
  doi: 10.1006/bbrc.2002.6384
– volume: 17
  start-page: 4037
  year: 1997
  ident: 10.1124/pr.114.010397_bib186
  article-title: Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.17-11-04037.1997
– volume: 280
  start-page: 40442
  year: 2005
  ident: 10.1124/pr.114.010397_bib281
  article-title: Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M501969200
– volume: 55
  start-page: 131
  year: 1993
  ident: 10.1124/pr.114.010397_bib69
  article-title: Electrical stimulation of reward sites in the ventral tegmental area increases dopamine transmission in the nucleus accumbens of the rat
  publication-title: Behav Brain Res
  doi: 10.1016/0166-4328(93)90109-4
– volume: 8
  start-page: 881
  year: 2005
  ident: 10.1124/pr.114.010397_bib115
  article-title: Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
  publication-title: Nat Neurosci
  doi: 10.1038/nn1478
– volume: 339
  start-page: 207
  year: 2014
  ident: 10.1124/pr.114.010397_bib121
  article-title: Comparison of dopamine transporter decline in a patient with Parkinson’s disease and normal aging effect
  publication-title: J Neurol Sci
  doi: 10.1016/j.jns.2014.01.015
– volume: 4
  start-page: 2737
  year: 1990
  ident: 10.1124/pr.114.010397_bib225
  article-title: Dopamine receptors and transporters in Parkinson's disease and schizophrenia
  publication-title: FASEB J
  doi: 10.1096/fasebj.4.10.2197154
– volume: 74
  start-page: 2221
  year: 2000
  ident: 10.1124/pr.114.010397_bib21
  article-title: Methamphetamine rapidly decreases vesicular dopamine uptake
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2000.0742221.x
– volume: 12
  start-page: 25
  year: 1965
  ident: 10.1124/pr.114.010397_bib93
  article-title: Metabolism of (H3)Norepinephrine in the Rat Brain
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.1965.tb10247.x
– volume: 69
  start-page: 71
  year: 2014
  ident: 10.1124/pr.114.010397_bib182
  article-title: The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse
  publication-title: Adv Pharmacol
  doi: 10.1016/B978-0-12-420118-7.00002-0
– volume: 61
  start-page: 1123
  year: 2011
  ident: 10.1124/pr.114.010397_bib44
  article-title: Insulin signaling and addiction
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2011.02.028
– volume: 65
  start-page: 634
  year: 2004
  ident: 10.1124/pr.114.010397_bib163
  article-title: Are mood disorders and obesity related? A review for the mental health professional
  publication-title: J Clin Psychiatry
  doi: 10.4088/JCP.v65n0507
– volume: 69
  start-page: 803
  year: 2011
  ident: 10.1124/pr.114.010397_bib46
  article-title: Age-specific progression of nigrostriatal dysfunction in Parkinson’s disease
  publication-title: Ann Neurol
  doi: 10.1002/ana.22284
– volume: 285
  start-page: 32616
  year: 2010
  ident: 10.1124/pr.114.010397_bib116
  article-title: Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M110.150565
– volume: 10
  start-page: 311
  year: 2000
  ident: 10.1124/pr.114.010397_bib245
  article-title: Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults
  publication-title: J Child Adolesc Psychopharmacol
  doi: 10.1089/cap.2000.10.311
– volume: 81
  start-page: 292
  year: 2002
  ident: 10.1124/pr.114.010397_bib159
  article-title: Dopamine transport function is elevated in cocaine users
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2002.00820.x
– volume: 295
  start-page: 149
  year: 1991
  ident: 10.1124/pr.114.010397_bib90
  article-title: Cloning and functional characterization of a cocaine-sensitive dopamine transporter
  publication-title: FEBS Lett
  doi: 10.1016/0014-5793(91)81406-X
– volume: 75
  start-page: 406
  year: 2005
  ident: 10.1124/pr.114.010397_bib239
  article-title: Mechanisms of neurotransmitter release by amphetamines: a review
  publication-title: Prog Neurobiol
  doi: 10.1016/j.pneurobio.2005.04.003
– volume: 20
  start-page: S35
  issue: Suppl 1
  year: 2014
  ident: 10.1124/pr.114.010397_bib236
  article-title: Genetics of Parkinson’s disease: the yield
  publication-title: Parkinsonism Relat Disord
  doi: 10.1016/S1353-8020(13)70011-7
– volume: 169
  start-page: 55
  year: 2012
  ident: 10.1124/pr.114.010397_bib178
  article-title: In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in cocaine abusers
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2011.11010126
– volume: 30
  start-page: 7917
  year: 2010
  ident: 10.1124/pr.114.010397_bib191
  article-title: Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5298-09.2010
– volume: 110
  start-page: 581
  year: 2009
  ident: 10.1124/pr.114.010397_bib206
  article-title: The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter-2
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2009.06135.x
– volume: 27
  start-page: 270
  year: 2004
  ident: 10.1124/pr.114.010397_bib39
  article-title: DAncing past the DAT at a DA synapse
  publication-title: Trends Neurosci
  doi: 10.1016/j.tins.2004.03.011
– volume: 46
  start-page: 10484
  year: 2007
  ident: 10.1124/pr.114.010397_bib1
  article-title: Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching
  publication-title: Biochemistry
  doi: 10.1021/bi700429z
– volume: 61
  start-page: 764
  year: 1993
  ident: 10.1124/pr.114.010397_bib165
  article-title: D2 receptors may modulate the function of the striatal transporter for dopamine: kinetic evidence from studies in vitro and in vivo
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.1993.tb02185.x
– volume: 479
  start-page: 93
  year: 2003
  ident: 10.1124/pr.114.010397_bib53
  article-title: Dopamine transporter as target for drug development of cocaine dependence medications
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2003.08.060
– volume: 9
  start-page: 1425
  year: 2008
  ident: 10.1124/pr.114.010397_bib65
  article-title: Trafficking of vesicular neurotransmitter transporters
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2008.00771.x
– volume: 124
  start-page: 3107
  year: 2014
  ident: 10.1124/pr.114.010397_bib104
  article-title: Missense dopamine transporter mutations associate with adult parkinsonism and ADHD
  publication-title: J Clin Invest
  doi: 10.1172/JCI73778
– volume: 25
  start-page: 1889
  year: 2005
  ident: 10.1124/pr.114.010397_bib49
  article-title: Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.4778-04.2005
– volume: 114
  start-page: 2283
  year: 1991
  ident: 10.1124/pr.114.010397_bib64
  article-title: Ageing and Parkinson’s disease: substantia nigra regional selectivity
  publication-title: Brain
  doi: 10.1093/brain/114.5.2283
– volume: 63
  start-page: 824
  year: 2006
  ident: 10.1124/pr.114.010397_bib229
  article-title: Association between obesity and psychiatric disorders in the US adult population
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archpsyc.63.7.824
– volume: 256
  start-page: 5773
  year: 1981
  ident: 10.1124/pr.114.010397_bib125
  article-title: Proton: substrate stoichiometries during active transport of biogenic amines in chromaffin ghosts
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(19)69274-4
– volume: 81
  start-page: 1035
  year: 2002
  ident: 10.1124/pr.114.010397_bib275
  article-title: D(3) receptor ligands modulate extracellular dopamine clearance in the nucleus accumbens
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2002.00893.x
– volume: 271
  start-page: 1444
  year: 1994
  ident: 10.1124/pr.114.010397_bib205
  article-title: Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(25)24030-7
– volume: 67
  start-page: 593
  year: 1996
  ident: 10.1124/pr.114.010397_bib10
  article-title: Modification of dopamine transporter function: effect of reactive oxygen species and dopamine
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.1996.67020593.x
– volume: 62
  start-page: 1872
  year: 2004
  ident: 10.1124/pr.114.010397_bib5
  article-title: Infantile Parkinsonism-dystonia and elevated dopamine metabolites in CSF
  publication-title: Neurology
  doi: 10.1212/01.WNL.0000126440.16612.51
– volume: 152
  start-page: 1159
  year: 2001
  ident: 10.1124/pr.114.010397_bib264
  article-title: An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles
  publication-title: J Cell Biol
  doi: 10.1083/jcb.152.6.1159
– volume: 346
  start-page: 2
  year: 2013
  ident: 10.1124/pr.114.010397_bib223
  article-title: Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.111.191056
– volume: 100
  start-page: 1387
  year: 2007
  ident: 10.1124/pr.114.010397_bib274
  article-title: The vesicular monoamine transporter 2 contains trafficking signals in both its N-glycosylation and C-terminal domains
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2006.04326.x
– volume: 26
  start-page: 1198
  year: 2006
  ident: 10.1124/pr.114.010397_bib15
  article-title: Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease
  publication-title: J Cereb Blood Flow Metab
  doi: 10.1038/sj.jcbfm.9600276
– volume: 339
  start-page: 1128
  year: 1992
  ident: 10.1124/pr.114.010397_bib62
  article-title: Insulin resistance and cigarette smoking
  publication-title: Lancet
  doi: 10.1016/0140-6736(92)90730-Q
– volume: 77
  start-page: 754
  year: 2001
  ident: 10.1124/pr.114.010397_bib32
  article-title: Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2001.00284.x
– volume: 304
  start-page: 1181
  year: 2003
  ident: 10.1124/pr.114.010397_bib220
  article-title: Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.102.045005
– volume: 6
  year: 2011
  ident: 10.1124/pr.114.010397_bib222
  article-title: The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0025790
– volume: 15
  start-page: 733
  year: 1999
  ident: 10.1124/pr.114.010397_bib103
  article-title: Synaptic vesicle biogenesis
  publication-title: Annu Rev Cell Dev Biol
  doi: 10.1146/annurev.cellbio.15.1.733
– volume: 7
  start-page: E847
  year: 2005
  ident: 10.1124/pr.114.010397_bib212
  article-title: Role of monoamine transporters in mediating psychostimulant effects
  publication-title: AAPS J
  doi: 10.1208/aapsj070481
– volume: 63
  start-page: 585
  year: 2011
  ident: 10.1124/pr.114.010397_bib137
  article-title: SLC6 neurotransmitter transporters: structure, function, and regulation
  publication-title: Pharmacol Rev
  doi: 10.1124/pr.108.000869
– volume: 59
  start-page: 419
  year: 1977
  ident: 10.1124/pr.114.010397_bib198
  article-title: Effect of neuroleptics and other drugs on monoamine uptake by membranes of adrenal chromaffin granules
  publication-title: Br J Pharmacol
  doi: 10.1111/j.1476-5381.1977.tb08395.x
– volume: 345
  start-page: 207
  year: 1998
  ident: 10.1124/pr.114.010397_bib50
  article-title: Inhibition of striatal dopamine transporter activity by 17beta-estradiol
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(98)00008-9
– volume: 85
  start-page: 351
  year: 2007
  ident: 10.1124/pr.114.010397_bib80
  article-title: RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.21125
– volume: 2
  year: 2004
  ident: 10.1124/pr.114.010397_bib131
  article-title: N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux
  publication-title: PLoS Biol
  doi: 10.1371/journal.pbio.0020078
– volume: 256
  start-page: 6541
  year: 1981
  ident: 10.1124/pr.114.010397_bib133
  article-title: Amine transport in chromaffin granule ghosts. pH dependence implies cationic form is translocated
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(19)69022-8
– volume: 30
  start-page: 121
  year: 2001
  ident: 10.1124/pr.114.010397_bib249
  article-title: Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
  publication-title: Neuron
  doi: 10.1016/S0896-6273(01)00267-7
– volume: 39
  start-page: 211
  year: 2008
  ident: 10.1124/pr.114.010397_bib18
  article-title: Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization
  publication-title: Mol Cell Neurosci
  doi: 10.1016/j.mcn.2008.06.011
– volume: 89
  start-page: 276
  year: 2011
  ident: 10.1124/pr.114.010397_bib85
  article-title: A randomized, placebo-controlled trial of sustained-release dextroamphetamine for treatment of methamphetamine addiction
  publication-title: Clin Pharmacol Ther
  doi: 10.1038/clpt.2010.307
– volume: 277
  start-page: 25178
  year: 2002
  ident: 10.1124/pr.114.010397_bib77
  article-title: Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M200294200
– volume: 106
  start-page: 233
  year: 2010
  ident: 10.1124/pr.114.010397_bib263
  article-title: Modafinil does not serve as a reinforcer in cocaine abusers
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2009.09.002
– volume: 102
  start-page: 16
  issue: Suppl 1
  year: 2007
  ident: 10.1124/pr.114.010397_bib31
  article-title: Structural and metabolic brain changes in the striatum associated with methamphetamine abuse
  publication-title: Addiction
  doi: 10.1111/j.1360-0443.2006.01782.x
– volume: 259
  start-page: 194
  year: 2014
  ident: 10.1124/pr.114.010397_bib247
  article-title: N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2013.11.059
– volume: 51
  start-page: 417
  year: 2006
  ident: 10.1124/pr.114.010397_bib75
  article-title: Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport
  publication-title: Neuron
  doi: 10.1016/j.neuron.2006.06.028
– volume: 47
  start-page: 369
  year: 2014
  ident: 10.1124/pr.114.010397_bib141
  article-title: Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases
  publication-title: BMB Rep
  doi: 10.5483/BMBRep.2014.47.7.086
– volume: 89
  start-page: 10993
  year: 1992
  ident: 10.1124/pr.114.010397_bib55
  article-title: Expression cloning of a reserpine-sensitive vesicular monoamine transporter
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.89.22.10993
– volume: 59
  start-page: 113
  year: 2001
  ident: 10.1124/pr.114.010397_bib160
  article-title: Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent
  publication-title: Mol Pharmacol
– volume: 19
  start-page: 7699
  year: 1999
  ident: 10.1124/pr.114.010397_bib166
  article-title: Membrane trafficking regulates the activity of the human dopamine transporter
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.19-18-07699.1999
– volume: 8
  year: 2013
  ident: 10.1124/pr.114.010397_bib38
  article-title: Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0060763
– volume: 8
  start-page: 73
  year: 2011
  ident: 10.1124/pr.114.010397_bib4
  article-title: Females are more vulnerable to drug abuse than males: evidence from preclinical studies and the role of ovarian hormones
  publication-title: Curr Top Behav Neurosci
  doi: 10.1007/7854_2010_93
– volume: 98
  start-page: 10055
  year: 2001
  ident: 10.1124/pr.114.010397_bib108
  article-title: Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.181344298
– volume: 160
  start-page: 47
  year: 2003
  ident: 10.1124/pr.114.010397_bib150
  article-title: Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.160.1.47
– volume: 28
  start-page: 9850
  year: 2008
  ident: 10.1124/pr.114.010397_bib16
  article-title: Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.3008-08.2008
– volume: 26
  start-page: 903
  year: 2000
  ident: 10.1124/pr.114.010397_bib51
  article-title: Prevalence and correlates of diabetes in national schizophrenia samples
  publication-title: Schizophr Bull
  doi: 10.1093/oxfordjournals.schbul.a033504
– volume: 64
  start-page: 1819
  year: 1995
  ident: 10.1124/pr.114.010397_bib89
  article-title: Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.1995.64041819.x
– volume: 72
  start-page: 405
  year: 2012
  ident: 10.1124/pr.114.010397_bib154
  article-title: R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2012.03.022
– volume: 18
  start-page: 927
  year: 1993
  ident: 10.1124/pr.114.010397_bib268
  article-title: A model of the sodium dependence of dopamine uptake in rat striatal synaptosomes
  publication-title: Neurochem Res
  doi: 10.1007/BF00998279
– volume: 57
  start-page: 253
  year: 2009
  ident: 10.1124/pr.114.010397_bib244
  article-title: Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors
  publication-title: Adv Pharmacol
  doi: 10.1016/S1054-3589(08)57007-4
– volume: 503
  start-page: 85
  year: 2013
  ident: 10.1124/pr.114.010397_bib195
  article-title: X-ray structure of dopamine transporter elucidates antidepressant mechanism
  publication-title: Nature
  doi: 10.1038/nature12533
– volume: 274
  start-page: 35794
  year: 1999
  ident: 10.1124/pr.114.010397_bib43
  article-title: Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
  publication-title: J Biol Chem
  doi: 10.1074/jbc.274.50.35794
– volume: 237
  start-page: 1219
  year: 1987
  ident: 10.1124/pr.114.010397_bib215
  article-title: Cocaine receptors on dopamine transporters are related to self-administration of cocaine
  publication-title: Science
  doi: 10.1126/science.2820058
– volume: 276
  start-page: 2045
  year: 1997
  ident: 10.1124/pr.114.010397_bib199
  article-title: Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
  publication-title: Science
  doi: 10.1126/science.276.5321.2045
– volume: 36
  start-page: 494
  year: 2009
  ident: 10.1124/pr.114.010397_bib2
  article-title: Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson’s disease
  publication-title: Neurobiol Dis
  doi: 10.1016/j.nbd.2009.09.002
– volume: 124
  start-page: 235
  year: 2009
  ident: 10.1124/pr.114.010397_bib273
  article-title: Anti-relapse medications: preclinical models for drug addiction treatment
  publication-title: Pharmacol Ther
  doi: 10.1016/j.pharmthera.2009.06.014
– volume: 298
  start-page: 172
  year: 2001
  ident: 10.1124/pr.114.010397_bib106
  article-title: Lobeline attenuates d-methamphetamine self-administration in rats
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)29365-4
– volume: 278
  start-page: 28274
  year: 2003
  ident: 10.1124/pr.114.010397_bib233
  article-title: Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M210652200
– volume: 21
  start-page: 522
  year: 2001
  ident: 10.1124/pr.114.010397_bib95
  article-title: Dextroamphetamine for cocaine-dependence treatment: a double-blind randomized clinical trial
  publication-title: J Clin Psychopharmacol
  doi: 10.1097/00004714-200110000-00010
– volume: 5
  start-page: 275
  year: 2000
  ident: 10.1124/pr.114.010397_bib98
  article-title: Systematic screening for DNA sequence variation in the coding region of the human dopamine transporter gene (DAT1)
  publication-title: Mol Psychiatry
  doi: 10.1038/sj.mp.4000711
– volume: 49
  start-page: 980
  year: 2010
  ident: 10.1124/pr.114.010397_bib168
  article-title: Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication--Adolescent Supplement (NCS-A)
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1016/j.jaac.2010.05.017
– volume: 49
  start-page: 110
  year: 2001
  ident: 10.1124/pr.114.010397_bib280
  article-title: Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects
  publication-title: Biol Psychiatry
  doi: 10.1016/S0006-3223(00)00981-1
– volume: 108
  start-page: 1575
  year: 2009
  ident: 10.1124/pr.114.010397_bib208
  article-title: Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: rat dorsal striatum versus nucleus accumbens
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2009.05910.x
– volume: 302
  start-page: 1084
  year: 2009
  ident: 10.1124/pr.114.010397_bib258
  article-title: Evaluating dopamine reward pathway in ADHD: clinical implications
  publication-title: JAMA
  doi: 10.1001/jama.2009.1308
– volume: 11
  start-page: 780
  year: 2008
  ident: 10.1124/pr.114.010397_bib12
  article-title: The binding sites for cocaine and dopamine in the dopamine transporter overlap
  publication-title: Nat Neurosci
  doi: 10.1038/nn.2146
– volume: 47
  start-page: 256
  issue: Suppl 1
  year: 2004
  ident: 10.1124/pr.114.010397_bib8
  article-title: Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2004.07.007
– volume: 17
  start-page: 39
  year: 2007
  ident: 10.1124/pr.114.010397_bib241
  article-title: Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis
  publication-title: Neuropsychol Rev
  doi: 10.1007/s11065-007-9019-9
– volume: 71
  start-page: 679
  year: 2009
  ident: 10.1124/pr.114.010397_bib34
  article-title: Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study
  publication-title: Clin Endocrinol (Oxf)
  doi: 10.1111/j.1365-2265.2009.03586.x
– volume: 368
  start-page: 543
  year: 2013
  ident: 10.1124/pr.114.010397_bib214
  article-title: Brain dopamine-serotonin vesicular transport disease and its treatment
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1207281
– volume: 286
  start-page: 5175
  year: 2011
  ident: 10.1124/pr.114.010397_bib78
  article-title: Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M110.187872
– volume: 15
  start-page: 916
  year: 2001
  ident: 10.1124/pr.114.010397_bib142
  article-title: Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
  publication-title: FASEB J
– volume: 8
  start-page: E196
  year: 2006
  ident: 10.1124/pr.114.010397_bib28
  article-title: Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse
  publication-title: AAPS J
  doi: 10.1208/aapsj080124
– volume: 354
  start-page: 2132
  year: 1999
  ident: 10.1124/pr.114.010397_bib52
  article-title: Dopamine transporter density in patients with attention deficit hyperactivity disorder
  publication-title: Lancet
  doi: 10.1016/S0140-6736(99)04030-1
– volume: 334
  start-page: 111
  year: 1997
  ident: 10.1124/pr.114.010397_bib71
  article-title: Oxygen radicals diminish dopamine transporter function in rat striatum
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(97)01175-8
– volume: 296
  start-page: 762
  year: 2001
  ident: 10.1124/pr.114.010397_bib23
  article-title: Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)38814-7
– volume: 285
  start-page: 27289
  year: 2010
  ident: 10.1124/pr.114.010397_bib57
  article-title: Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M110.131003
– volume: 336
  start-page: 575
  year: 2011
  ident: 10.1124/pr.114.010397_bib147
  article-title: N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.110.173260
– volume: 330
  start-page: 802
  year: 2009
  ident: 10.1124/pr.114.010397_bib243
  article-title: Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.109.154302
– volume: 98
  start-page: 70
  year: 2008
  ident: 10.1124/pr.114.010397_bib41
  article-title: Dopamine transporter levels in cocaine dependent subjects
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2008.04.014
– volume: 272
  start-page: 6752
  year: 1997
  ident: 10.1124/pr.114.010397_bib135
  article-title: Phosphorylation of a vesicular monoamine transporter by casein kinase II
  publication-title: J Biol Chem
  doi: 10.1074/jbc.272.10.6752
– volume: 148
  start-page: 1
  year: 1965
  ident: 10.1124/pr.114.010397_bib145
  article-title: Elucidation of the rate-limiting step in norepinephrine biosynthesis in the perfused guinea-pig heart
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(25)27006-9
– volume: 49
  start-page: 750
  year: 2005
  ident: 10.1124/pr.114.010397_bib124
  article-title: Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2005.08.018
– volume: 63
  start-page: 76
  year: 2012
  ident: 10.1124/pr.114.010397_bib6
  article-title: You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2012.02.005
– volume: 474
  start-page: 223
  year: 2003
  ident: 10.1124/pr.114.010397_bib251
  article-title: Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson’s neurodegeneration
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(03)02080-6
– volume: 69
  start-page: 628
  year: 2011
  ident: 10.1124/pr.114.010397_bib237
  article-title: How addictive drugs disrupt presynaptic dopamine neurotransmission
  publication-title: Neuron
  doi: 10.1016/j.neuron.2011.02.010
– volume: 133
  start-page: 1072
  year: 1961
  ident: 10.1124/pr.114.010397_bib47
  article-title: Uptake of tritium-labeled norepinephrine in brain and other tissues of cat in vitro
  publication-title: Science
  doi: 10.1126/science.133.3458.1072
– volume: 24
  start-page: 847
  year: 1975
  ident: 10.1124/pr.114.010397_bib110
  article-title: Studies on the distinction between uptake inhibition and release of (3H)dopamine in rat brain tissue slices
  publication-title: Biochem Pharmacol
  doi: 10.1016/0006-2952(75)90152-5
– volume: 74
  start-page: 2217
  year: 2000
  ident: 10.1124/pr.114.010397_bib114
  article-title: Analysis of VMAT2 binding after methamphetamine or MPTP treatment: disparity between homogenates and vesicle preparations
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2000.0742217.x
– volume: 10
  start-page: 54
  year: 2011
  ident: 10.1124/pr.114.010397_bib139
  article-title: Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study
  publication-title: Lancet Neurol
  doi: 10.1016/S1474-4422(10)70269-6
– volume: 315
  start-page: 397
  year: 2005
  ident: 10.1124/pr.114.010397_bib48
  article-title: Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-2-[bis-(4-fluorophenyl)methoxy]ethyl-4-(3-phenylpropyl)piperazine], and benztropine analogs
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.105.091231
– volume: 101
  start-page: 34
  year: 2009
  ident: 10.1124/pr.114.010397_bib174
  article-title: Effects of oral methamphetamine on cocaine use: a randomized, double-blind, placebo-controlled trial
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2008.10.016
– volume: 62
  start-page: 617
  year: 2005
  ident: 10.1124/pr.114.010397_bib130
  article-title: Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archpsyc.62.6.617
– volume: 70
  start-page: 185
  year: 2013
  ident: 10.1124/pr.114.010397_bib107
  article-title: Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2013.277
– volume: 339
  start-page: 662
  year: 2011
  ident: 10.1124/pr.114.010397_bib112
  article-title: Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.111.185025
– volume: 295
  start-page: 1077
  year: 2000
  ident: 10.1124/pr.114.010397_bib169
  article-title: Methamphetamine-induced rapid decrease in dopamine transporter function: role of dopamine and hyperthermia
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)39008-1
– volume: 280
  start-page: 35617
  year: 2005
  ident: 10.1124/pr.114.010397_bib173
  article-title: Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M506618200
– volume: 103
  start-page: 1219
  year: 2007
  ident: 10.1124/pr.114.010397_bib61
  article-title: A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2007.04837.x
– volume: 1184
  start-page: 188
  year: 2010
  ident: 10.1124/pr.114.010397_bib101
  article-title: The progression of pathology in Parkinson’s disease
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.2009.05118.x
– volume: 62
  start-page: 155
  year: 2010
  ident: 10.1124/pr.114.010397_bib88
  article-title: Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines
  publication-title: Pharmacol Rev
  doi: 10.1124/pr.109.002071
– volume: 10
  start-page: 582
  year: 2014
  ident: 10.1124/pr.114.010397_bib102
  article-title: PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein
  publication-title: Nat Chem Biol
  doi: 10.1038/nchembio.1545
– volume: 18
  start-page: 8417
  year: 1998
  ident: 10.1124/pr.114.010397_bib162
  article-title: Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.18-20-08417.1998
– volume: 18
  start-page: 313
  year: 2007
  ident: 10.1124/pr.114.010397_bib172
  article-title: Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter
  publication-title: Mol Biol Cell
  doi: 10.1091/mbc.e06-08-0704
– volume: 254
  start-page: 576
  year: 1991
  ident: 10.1124/pr.114.010397_bib228
  article-title: Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA
  publication-title: Science
  doi: 10.1126/science.1948034
– volume: 278
  start-page: 4990
  year: 2003
  ident: 10.1124/pr.114.010397_bib97
  article-title: N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M205058200
– volume: 49
  start-page: 7
  year: 1997
  ident: 10.1124/pr.114.010397_bib242
  article-title: Murine vesicular monoamine transporter 2: molecular cloning and genomic structure
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/S0169-328X(97)00116-2
– volume: 48
  start-page: 1067
  year: 2009
  ident: 10.1124/pr.114.010397_bib94
  article-title: Proline-directed phosphorylation of the dopamine transporter N-terminal domain
  publication-title: Biochemistry
  doi: 10.1021/bi801696n
– volume: 284
  start-page: 592
  year: 1998
  ident: 10.1124/pr.114.010397_bib283
  article-title: Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)37287-8
– volume: 35
  start-page: 217
  year: 2010
  ident: 10.1124/pr.114.010397_bib134
  article-title: Neurocircuitry of addiction
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2009.110
– volume: 18
  start-page: pyv024
  year: 2015
  ident: 10.1124/pr.114.010397_bib7
  article-title: Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents
  publication-title: Int J Neuropsychopharmacol
  doi: 10.1093/ijnp/pyv024
– volume: 312
  start-page: 160
  year: 2005
  ident: 10.1124/pr.114.010397_bib60
  article-title: Lobeline attenuates methamphetamine-induced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.104.072264
– volume: 42
  start-page: 423
  year: 2008
  ident: 10.1124/pr.114.010397_bib99
  article-title: PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity
  publication-title: Neuropeptides
  doi: 10.1016/j.npep.2008.04.003
– volume: 31
  start-page: 327
  year: 1988
  ident: 10.1124/pr.114.010397_bib183
  article-title: Effects of cocaine on release and uptake of dopamine in vivo: differentiation by mathematical modeling
  publication-title: Pharmacol Biochem Behav
  doi: 10.1016/0091-3057(88)90354-1
– volume: 60
  start-page: 527
  year: 1993
  ident: 10.1124/pr.114.010397_bib238
  article-title: Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.1993.tb03181.x
– volume: 964
  start-page: 107
  year: 2003
  ident: 10.1124/pr.114.010397_bib67
  article-title: Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
  publication-title: Brain Res
  doi: 10.1016/S0006-8993(02)04087-8
– volume: 278
  start-page: 2731
  year: 2003
  ident: 10.1124/pr.114.010397_bib248
  article-title: Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M201926200
– volume: 20
  start-page: 424
  year: 1999
  ident: 10.1124/pr.114.010397_bib170
  article-title: Dopamine transporters and neuronal injury
  publication-title: Trends Pharmacol Sci
  doi: 10.1016/S0165-6147(99)01379-6
– volume: 348
  start-page: 174
  year: 2014
  ident: 10.1124/pr.114.010397_bib111
  article-title: Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.113.208264
– volume: 220
  start-page: 9
  year: 1999
  ident: 10.1124/pr.114.010397_bib266
  article-title: Membrane-initiated steroid actions and the proteins that mediate them
  publication-title: Proc Soc Exp Biol Med
– volume: 105
  start-page: 146
  year: 2010
  ident: 10.1124/pr.114.010397_bib155
  article-title: Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence
  publication-title: Addiction
  doi: 10.1111/j.1360-0443.2009.02717.x
– volume: 83
  start-page: 53
  year: 1994
  ident: 10.1124/pr.114.010397_bib193
  article-title: Developmentally regulated glycosylation of dopamine transporter
  publication-title: Brain Res Dev Brain Res
  doi: 10.1016/0165-3806(94)90178-3
– volume: 113
  start-page: 27
  year: 2010
  ident: 10.1124/pr.114.010397_bib58
  article-title: Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2010.06599.x
– volume: 10
  start-page: 286
  year: 2002
  ident: 10.1124/pr.114.010397_bib224
  article-title: Double-blind placebo-controlled trial of methylphenidate in the treatment of adult ADHD patients with comorbid cocaine dependence
  publication-title: Exp Clin Psychopharmacol
  doi: 10.1037/1064-1297.10.3.286
– volume: 97
  start-page: 6850
  year: 2000
  ident: 10.1124/pr.114.010397_bib221
  article-title: Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.110035297
– volume: 287
  start-page: 12293
  year: 2012
  ident: 10.1124/pr.114.010397_bib157
  article-title: Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M111.294702
– volume: 271
  start-page: 21672
  year: 1996
  ident: 10.1124/pr.114.010397_bib255
  article-title: Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis
  publication-title: J Biol Chem
  doi: 10.1074/jbc.271.35.21672
– volume: 22
  start-page: 8705
  year: 2002
  ident: 10.1124/pr.114.010397_bib219
  article-title: Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.22-19-08705.2002
– volume: 6
  start-page: 157
  year: 2005
  ident: 10.1124/pr.114.010397_bib234
  article-title: Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2005.00259.x
– volume: 73
  start-page: 813
  year: 2008
  ident: 10.1124/pr.114.010397_bib153
  article-title: Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors
  publication-title: Mol Pharmacol
  doi: 10.1124/mol.107.039800
– volume: 1
  start-page: 5
  year: 2006
  ident: 10.1124/pr.114.010397_bib265
  article-title: Estradiol effects on the dopamine transporter - protein levels, subcellular location, and function
  publication-title: J Mol Signal
  doi: 10.1186/1750-2187-1-5
– volume: 4
  year: 2014
  ident: 10.1124/pr.114.010397_bib19
  article-title: SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking
  publication-title: Transl Psychiatry
  doi: 10.1038/tp.2014.90
– volume: 73
  start-page: 679
  year: 2003
  ident: 10.1124/pr.114.010397_bib209
  article-title: Neurotensin agonists: possible drugs for treatment of psychostimulant abuse
  publication-title: Life Sci
  doi: 10.1016/S0024-3205(03)00388-6
– volume: 5
  start-page: 971
  year: 2002
  ident: 10.1124/pr.114.010397_bib120
  article-title: Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons
  publication-title: Nat Neurosci
  doi: 10.1038/nn920
– volume: 2
  start-page: 311
  year: 1997
  ident: 10.1124/pr.114.010397_bib87
  article-title: Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism
  publication-title: Mol Psychiatry
  doi: 10.1038/sj.mp.4000290
– volume: 102
  start-page: 3495
  year: 2005
  ident: 10.1124/pr.114.010397_bib128
  article-title: Amphetamine induces dopamine efflux through a dopamine transporter channel
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0407737102
– volume: 644
  start-page: 331
  year: 1994
  ident: 10.1124/pr.114.010397_bib68
  article-title: Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra
  publication-title: Brain Res
  doi: 10.1016/0006-8993(94)91698-5
– volume: 44
  start-page: 73
  year: 2013
  ident: 10.1124/pr.114.010397_bib256
  article-title: The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens
  publication-title: Prog Neuropsychopharmacol Biol Psychiatry
  doi: 10.1016/j.pnpbp.2013.01.016
– volume: 17
  start-page: 230
  year: 2010
  ident: 10.1124/pr.114.010397_bib270
  article-title: Advances in the treatment of attention-deficit/hyperactivity disorder: a guide for pediatric neurologists
  publication-title: Semin Pediatr Neurol
  doi: 10.1016/j.spen.2010.10.005
– volume: 164
  start-page: 121
  year: 2002
  ident: 10.1124/pr.114.010397_bib156
  article-title: Biological basis of sex differences in drug abuse: preclinical and clinical studies
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-002-1183-2
– volume: 92
  start-page: 8773
  year: 1995
  ident: 10.1124/pr.114.010397_bib187
  article-title: The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.92.19.8773
– volume: 379
  start-page: 606
  year: 1996
  ident: 10.1124/pr.114.010397_bib92
  article-title: Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
  publication-title: Nature
  doi: 10.1038/379606a0
– volume: 323
  start-page: 738
  year: 2007
  ident: 10.1124/pr.114.010397_bib261
  article-title: Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.107.126888
– volume: 20
  start-page: 125
  year: 1997
  ident: 10.1124/pr.114.010397_bib151
  article-title: The role of vesicular transport proteins in synaptic transmission and neural degeneration
  publication-title: Annu Rev Neurosci
  doi: 10.1146/annurev.neuro.20.1.125
– volume: 37
  start-page: 68
  year: 1996
  ident: 10.1124/pr.114.010397_bib176
  article-title: Diabetes mellitus in schizophrenic patients
  publication-title: Compr Psychiatry
  doi: 10.1016/S0010-440X(96)90054-1
– volume: 329
  start-page: 677
  year: 2009
  ident: 10.1124/pr.114.010397_bib113
  article-title: Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.108.145813
– volume: 105
  start-page: 1683
  year: 2008
  ident: 10.1124/pr.114.010397_bib76
  article-title: Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2008.05262.x
– volume: 111
  start-page: E4779
  year: 2014
  ident: 10.1124/pr.114.010397_bib167
  article-title: The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1417294111
– volume: 658
  start-page: 156
  year: 2011
  ident: 10.1124/pr.114.010397_bib164
  article-title: Eating high-fat chow enhances sensitization to the effects of methamphetamine on locomotion in rats
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2011.02.027
– volume: 93
  start-page: 5166
  year: 1996
  ident: 10.1124/pr.114.010397_bib56
  article-title: Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.93.10.5166
– volume: 5
  start-page: 237
  year: 1990
  ident: 10.1124/pr.114.010397_bib231
  article-title: A tolerance study of single and multiple dosing of the selective dopamine uptake inhibitor GBR 12909 in healthy subjects
  publication-title: Int Clin Psychopharmacol
  doi: 10.1097/00004850-199010000-00001
– volume: 504
  start-page: 27
  year: 2004
  ident: 10.1124/pr.114.010397_bib250
  article-title: Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2004.09.049
– volume: 58
  start-page: 303
  year: 2008
  ident: 10.1124/pr.114.010397_bib207
  article-title: Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway
  publication-title: Brain Res Brain Res Rev
  doi: 10.1016/j.brainresrev.2008.02.004
– volume: 52
  start-page: 6768
  year: 2009
  ident: 10.1124/pr.114.010397_bib27
  article-title: Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction
  publication-title: J Med Chem
  doi: 10.1021/jm901189z
– volume: 4
  start-page: 1580
  year: 2013
  ident: 10.1124/pr.114.010397_bib210
  article-title: A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter
  publication-title: Nat Commun
  doi: 10.1038/ncomms2568
– volume: 185
  start-page: 327
  year: 2006
  ident: 10.1124/pr.114.010397_bib123
  article-title: Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-006-0330-6
– volume: 67
  start-page: 59
  year: 2010
  ident: 10.1124/pr.114.010397_bib177
  article-title: Brain serotonin and dopamine transporter bindings in adults with high-functioning autism
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2009.137
– volume: 54
  start-page: 173
  year: 2004
  ident: 10.1124/pr.114.010397_bib262
  article-title: L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism
  publication-title: Synapse
  doi: 10.1002/syn.20075
– volume: 17
  start-page: 957
  year: 1968
  ident: 10.1124/pr.114.010397_bib36
  article-title: Quantitative studies of norepinephrine uptake by synaptosomes
  publication-title: Biochem Pharmacol
  doi: 10.1016/0006-2952(68)90354-7
– volume: 21
  start-page: 1413
  year: 2001
  ident: 10.1124/pr.114.010397_bib284
  article-title: Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.21-04-01413.2001
– volume: 64
  start-page: 932
  year: 2007
  ident: 10.1124/pr.114.010397_bib260
  article-title: Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archpsyc.64.8.932
– volume: 95
  start-page: 4029
  year: 1998
  ident: 10.1124/pr.114.010397_bib126
  article-title: Profound neuronal plasticity in response to inactivation of the dopamine transporter
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.95.7.4029
– volume: 46
  start-page: 148
  year: 2011
  ident: 10.1124/pr.114.010397_bib202
  article-title: Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons
  publication-title: Mol Cell Neurosci
  doi: 10.1016/j.mcn.2010.08.016
– volume: 6
  start-page: 455
  year: 2006
  ident: 10.1124/pr.114.010397_bib252
  article-title: A review of the use of modafinil for attention-deficit hyperactivity disorder
  publication-title: Expert Rev Neurother
  doi: 10.1586/14737175.6.4.455
– volume: 26
  start-page: 2127
  year: 2007
  ident: 10.1124/pr.114.010397_bib143
  article-title: Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
  publication-title: EMBO J
  doi: 10.1038/sj.emboj.7601656
– volume: 215
  start-page: 53
  year: 1996
  ident: 10.1124/pr.114.010397_bib74
  article-title: Amphetamine releases dopamine from synaptic vesicles by dual mechanisms
  publication-title: Neurosci Lett
  doi: 10.1016/S0304-3940(96)12963-3
– volume: 24
  start-page: 7024
  year: 2004
  ident: 10.1124/pr.114.010397_bib13
  article-title: Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.1863-04.2004
– volume: 17
  start-page: 485
  year: 1997
  ident: 10.1124/pr.114.010397_bib96
  article-title: Replacement medication for cocaine dependence: methylphenidate
  publication-title: J Clin Psychopharmacol
  doi: 10.1097/00004714-199712000-00008
– volume: 1321
  start-page: 51
  year: 2010
  ident: 10.1124/pr.114.010397_bib33
  article-title: The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2009.12.093
– volume: 34
  start-page: 8210
  year: 2014
  ident: 10.1124/pr.114.010397_bib197
  article-title: Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5456-13.2014
– volume: 406
  start-page: 1
  year: 2000
  ident: 10.1124/pr.114.010397_bib70
  article-title: Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
  publication-title: Eur J Pharmacol
  doi: 10.1016/S0014-2999(00)00639-7
– volume: 36
  start-page: 359
  year: 2011
  ident: 10.1124/pr.114.010397_bib189
  article-title: Insulin regulation of monoamine signaling: pathway to obesity
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2010.167
– volume: 279
  start-page: 54380
  year: 2004
  ident: 10.1124/pr.114.010397_bib122
  article-title: Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M409282200
– volume: 49
  start-page: 724
  year: 2005
  ident: 10.1124/pr.114.010397_bib161
  article-title: Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2005.08.003
– volume: 53
  start-page: 935
  year: 2002
  ident: 10.1124/pr.114.010397_bib63
  article-title: Obesity-depression associations in the population
  publication-title: J Psychosom Res
  doi: 10.1016/S0022-3999(02)00308-2
– volume: 14
  start-page: 469
  year: 2011
  ident: 10.1124/pr.114.010397_bib40
  article-title: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT
  publication-title: Nat Neurosci
  doi: 10.1038/nn.2781
– volume: 57
  start-page: 640
  year: 2009
  ident: 10.1124/pr.114.010397_bib217
  article-title: Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2009.08.013
– volume: 456
  start-page: 904
  year: 2008
  ident: 10.1124/pr.114.010397_bib129
  article-title: Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
  publication-title: Nature
  doi: 10.1038/nature07605
– volume: 335
  start-page: 207
  year: 2010
  ident: 10.1124/pr.114.010397_bib100
  article-title: Methamphetamine-induced dopamine transporter complex formation and dopaminergic deficits: the role of D2 receptor activation
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.110.166660
– volume: 94
  start-page: 1402
  year: 2005
  ident: 10.1124/pr.114.010397_bib192
  article-title: Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2005.03289.x
– volume: 29
  start-page: 6794
  year: 2009
  ident: 10.1124/pr.114.010397_bib59
  article-title: Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.4177-08.2009
– volume: 137
  start-page: 1107
  year: 2014
  ident: 10.1124/pr.114.010397_bib180
  article-title: Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood
  publication-title: Brain
  doi: 10.1093/brain/awu022
– volume: 16
  start-page: 436
  year: 1996
  ident: 10.1124/pr.114.010397_bib188
  article-title: The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.16-02-00436.1996
– volume: 17
  start-page: 960
  year: 1997
  ident: 10.1124/pr.114.010397_bib232
  article-title: Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.17-03-00960.1997
– volume: 120
  start-page: 35
  year: 2012
  ident: 10.1124/pr.114.010397_bib25
  article-title: Increased risk of Parkinson’s disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs
  publication-title: Drug Alcohol Depend
  doi: 10.1016/j.drugalcdep.2011.06.013
– volume: 26
  start-page: 8195
  year: 2006
  ident: 10.1124/pr.114.010397_bib235
  article-title: RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.1301-06.2006
– volume: 133
  start-page: 167
  year: 2015
  ident: 10.1124/pr.114.010397_bib276
  article-title: Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities
  publication-title: J Neurochem
  doi: 10.1111/jnc.13025
– volume: 282
  start-page: 1358
  year: 1997
  ident: 10.1124/pr.114.010397_bib278
  article-title: Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes
  publication-title: J Pharmacol Exp Ther
  doi: 10.1016/S0022-3565(24)36962-9
– volume: 317
  start-page: 1390
  year: 2007
  ident: 10.1124/pr.114.010397_bib277
  article-title: LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
  publication-title: Science
  doi: 10.1126/science.1147614
– volume: 20
  start-page: 7297
  year: 2000
  ident: 10.1124/pr.114.010397_bib200
  article-title: Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.20-19-07297.2000
– volume: 32
  start-page: 5385
  year: 2012
  ident: 10.1124/pr.114.010397_bib218
  article-title: Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.6033-11.2012
– volume: 272
  start-page: 15541
  year: 1997
  ident: 10.1124/pr.114.010397_bib254
  article-title: Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
  publication-title: J Biol Chem
  doi: 10.1074/jbc.272.24.15541
– volume: 81
  start-page: 859
  year: 2002
  ident: 10.1124/pr.114.010397_bib30
  article-title: PI 3-kinase regulation of dopamine uptake
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2002.00892.x
– volume: 16
  start-page: 4135
  year: 1996
  ident: 10.1124/pr.114.010397_bib184
  article-title: Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: potential sites for somatodendritic storage and release of dopamine
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.16-13-04135.1996
– volume: 13
  start-page: 362
  year: 2013
  ident: 10.1124/pr.114.010397_bib3
  article-title: Vesicular integrity in Parkinson’s disease
  publication-title: Curr Neurol Neurosci Rep
  doi: 10.1007/s11910-013-0362-3
– volume: 119
  start-page: 1595
  year: 2009
  ident: 10.1124/pr.114.010397_bib140
  article-title: Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia
  publication-title: J Clin Invest
– volume: 5
  year: 2007
  ident: 10.1124/pr.114.010397_bib271
  article-title: Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine
  publication-title: PLoS Biol
  doi: 10.1371/journal.pbio.0050274
– volume: S1
  start-page: 003
  year: 2011
  ident: 10.1124/pr.114.010397_bib138
  article-title: Investigating methamphetamine craving using the extinction-reinstatement model in the rat
  publication-title: J Addict Res Ther
– volume: 592
  start-page: 109
  year: 2008
  ident: 10.1124/pr.114.010397_bib226
  article-title: Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2008.07.002
– volume: 20
  start-page: 163
  year: 1996
  ident: 10.1124/pr.114.010397_bib269
  article-title: Substance use among women with eating disorders
  publication-title: Int J Eat Disord
  doi: 10.1002/(SICI)1098-108X(199609)20:2<163::AID-EAT6>3.0.CO;2-E
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Snippet Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human...
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SubjectTerms Adrenergic Uptake Inhibitors - pharmacology
Animals
Central Nervous System Diseases - physiopathology
Dopamine - metabolism
Dopamine Agents - pharmacology
Dopamine Plasma Membrane Transport Proteins - pharmacology
Dopamine Plasma Membrane Transport Proteins - physiology
Glycosylation
Humans
Phosphorylation - physiology
Review
Signal Transduction
Synaptic Transmission
Vesicular Monoamine Transport Proteins - classification
Vesicular Monoamine Transport Proteins - pharmacology
Vesicular Monoamine Transport Proteins - physiology
Title Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease
URI https://dx.doi.org/10.1124/pr.114.010397
https://www.ncbi.nlm.nih.gov/pubmed/26408528
https://www.proquest.com/docview/1718075688
https://pubmed.ncbi.nlm.nih.gov/PMC4630566
http://pharmrev.aspetjournals.org/content/pharmrev/67/4/1005.full.pdf
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