IgG4-Related Sclerosing Disease Involving the Superior Vena Cava and the Atrial Septum of the Heart
A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to t...
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| Published in | Yonsei medical journal Vol. 54; no. 5; pp. 1285 - 1288 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
Yonsei University College of Medicine
01.09.2013
연세대학교의과대학 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0513-5796 1976-2437 1976-2437 |
| DOI | 10.3349/ymj.2013.54.5.1285 |
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| Abstract | A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up. |
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| AbstractList | A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up. A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up.A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up. A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up. KCI Citation Count: 9 |
| Author | Yoon, Yong-Nam Kim, Se Hoon Song, Changho Koh, Myoung Ju Joung, Boyoung |
| AuthorAffiliation | 2 Department of Pathology, Yonsei University College of Medicine, Seoul, Korea 3 Department of Cardiothoracic Surgery, Yonsei University College of Medicine, Seoul, Korea 1 Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea |
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| CitedBy_id | crossref_primary_10_2169_internalmedicine_8049_21 crossref_primary_10_1016_j_carpath_2014_08_001 crossref_primary_10_2169_internalmedicine_4054_19 crossref_primary_10_3390_biology11081168 crossref_primary_10_1007_s10067_018_4048_8 crossref_primary_10_1097_MD_0000000000034533 crossref_primary_10_1536_ihj_18_349 crossref_primary_10_1016_j_athoracsur_2019_01_029 crossref_primary_10_1016_j_athoracsur_2014_12_051 crossref_primary_10_1053_j_jvca_2021_03_022 crossref_primary_10_1155_2015_392893 crossref_primary_10_1111_echo_15645 crossref_primary_10_1097_BOR_0000000000000133 crossref_primary_10_1093_rheumatology_keae494 crossref_primary_10_1111_echo_14828 crossref_primary_10_1136_annrheumdis_2018_213042 crossref_primary_10_1536_ihj_17_467 crossref_primary_10_2169_internalmedicine_2509_18 |
| Cites_doi | 10.2169/internalmedicine.45.1601 10.1016/j.jjcc.2011.10.005 10.1046/j.1563-258X.2002.02031.x 10.1080/00365520410008033 10.1186/1741-7015-4-23 10.1080/00365520701731263 10.1056/NEJM200103083441005 10.1148/radiol.11102250 10.1016/j.jjcc.2011.07.014 10.1159/000085277 10.1097/PAP.0b013e3181ee63ce |
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| SubjectTerms | Atrial Septum - pathology Case Report Female Humans Immunoglobulin G - blood Middle Aged Pacemaker, Artificial Sclerosis - complications Sclerosis - diagnosis Sclerosis - therapy Syncope - etiology Vena Cava, Superior - pathology 의학일반 |
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| Title | IgG4-Related Sclerosing Disease Involving the Superior Vena Cava and the Atrial Septum of the Heart |
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