Positive preoperative cultures but not bacterial species predict postoperative urine culture results after holmium laser enucleation of the prostate

• Published in: Urology annals Vol. 16; no. 4; pp. 292 - 295
• Main Authors: Doersch, Karen M., Campbell, Timothy D., Li, Ashley, Jain, Rajat K., Quarrier, Scott O.
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow 01.10.2024; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Edition: 2
• Subjects: antibiotic stewardship; bacteriuria; benign prostatic hyperplasia; Health aspects; Lasers in surgery; Original; Original Article; perioperative antibiotic prophylaxis; Prostate; Risk factors; Urinary retention; urinary tract infection; Urinary tract infections; Urine; bacteriuria; Antibiotic stewardship; perioperative antibiotic prophylaxis; benign prostatic hyperplasia; urinary tract infection
• ISSN: 0974-7796; 0974-7834; 0974-7834
• DOI: 10.4103/ua.ua_31_24

Purpose: The purpose of this study was to evaluate risk factors associated with positive urine cultures following holmium laser enucleation of the prostate (HoLEP). Materials and Methods: The data from a prospectively maintained database were analyzed to evaluate urine culture results following HoLEP and determine the contribution of predefined variables (age, prostate size, Charlson comorbidity score, surgical time [surrogate for case difficulty], the presence of a catheter preoperatively, postoperative urinary retention, and preoperative positive culture) on urine culture positivity at 60 days postoperatively. Statistical analyses included logistic regression and ANOVA. Results: The data from 136 subjects were included in the database and were evaluated at a median of 13.37 ± 6.72 months after their HoLEP. Postoperative positive cultures were noted in 23 subjects (16.91%). Preoperative positive cultures were found to predict positive postoperative urine cultures (odds ratio: 3.78, confidence interval: 1.18-12.78, P = 0.03). However, the preoperative and postoperative results were discordant in 9 of 14 subjects with both positive preoperative and postoperative cultures. Conclusions: Positive preoperative cultures were predictive of positive postoperative cultures. However, the pre- and postoperative results were often discordant. Host factors increasing susceptibility to bacteriuria may explain these findings.