Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy
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| Published in | Journal of Clinical Microbiology Vol. 41; no. 5; pp. 2153 - 2155 |
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| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
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American Society for Microbiology
01.05.2003
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| ISSN | 0095-1137 1098-660X 1070-633X 1098-660X |
| DOI | 10.1128/JCM.41.5.2153-2155.2003 |
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| AbstractList | With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti- gp41 titers and Western blot band intensities. With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities. Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JCM About JCM Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JCM RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0095-1137 Online ISSN: 1098-660X Copyright © 2014 by the American Society for Microbiology. For an alternate route to JCM .asm.org, visit: JCM |
| Author | Bernard M. Branson Robert J. O'Connell Thomas C. VanCott Jennifer A. Malia Caroline C. De Witt Nelson L. Michael Hassan Zahwa Matthew J. Dolan William P. Bradley Teresa M. Merritt |
| AuthorAffiliation | Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236, 1 Division of Retrovirology, Walter Reed Army Institute for Research, 2 Henry M. Jackson Foundation, Rockville, Maryland 20850, 3 National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333 4 |
| AuthorAffiliation_xml | – name: Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236, 1 Division of Retrovirology, Walter Reed Army Institute for Research, 2 Henry M. Jackson Foundation, Rockville, Maryland 20850, 3 National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333 4 |
| Author_xml | – sequence: 1 givenname: Robert J. surname: O'Connell fullname: O'Connell, Robert J. organization: Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236 – sequence: 2 givenname: Teresa M. surname: Merritt fullname: Merritt, Teresa M. organization: Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236 – sequence: 3 givenname: Jennifer A. surname: Malia fullname: Malia, Jennifer A. organization: Division of Retrovirology, Walter Reed Army Institute for Research – sequence: 4 givenname: Thomas C. surname: VanCott fullname: VanCott, Thomas C. organization: Henry M. Jackson Foundation, Rockville, Maryland 20850 – sequence: 5 givenname: Matthew J. surname: Dolan fullname: Dolan, Matthew J. organization: Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236 – sequence: 6 givenname: Hassan surname: Zahwa fullname: Zahwa, Hassan organization: Division of Retrovirology, Walter Reed Army Institute for Research – sequence: 7 givenname: William P. surname: Bradley fullname: Bradley, William P. organization: Henry M. Jackson Foundation, Rockville, Maryland 20850 – sequence: 8 givenname: Bernard M. surname: Branson fullname: Branson, Bernard M. organization: National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333 – sequence: 9 givenname: Nelson L. surname: Michael fullname: Michael, Nelson L. organization: Division of Retrovirology, Walter Reed Army Institute for Research – sequence: 10 givenname: Caroline C. surname: De Witt fullname: De Witt, Caroline C. organization: Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236 |
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| Keywords | Performance evaluation Human Immunopathology HIV-1 virus Antibody Retroviridae AIDS Immune deficiency Lentivirus Infection Virus Chemotherapy Rapid technique Viral disease Antiviral Human immunodeficiency virus Diagnosis |
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Mendeley... With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the... |
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| SubjectTerms | Adult Antiretroviral Therapy, Highly Active Biological and medical sciences Blotting, Western Case-Control Studies False Negative Reactions Female HIV Antibodies - analysis HIV Antibodies - blood HIV Envelope Protein gp41 - immunology HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - immunology HIV-1 - immunology Human viral diseases Humans Immunoassay - methods Immunoassay - statistics & numerical data Infectious diseases Male Medical sciences Middle Aged Mouth Mucosa - immunology Sensitivity and Specificity Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology |
| Title | Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy |
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