Quantitative structure/property relationship analysis of Caco‐2 permeability using a genetic algorithm‐based partial least squares method - Yamashita, Fumiyoshi; Wanchana, Suchada; Hashida, Mitsuru (Journal of pharmaceutical sciences, 2002)
Keywords: Algorithms; Analysis; Biological and medical sciences; Caco-2 Cells; Caco-2 permeability; Cell Membrane Permeability - physiology; Databases, Genetic; General pharmacology; genetic algorithm; Genetics - statistics & numerical data; Humans; Least-Squares Analysis; Medical sciences; Molconn-Z; Molecular Weight; partial least squares; Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions; Pharmacology. Drug treatments; Quantitative Structure-Activity Relationship; quantitative structure-property relationship; genetic algorithm; Caco‐2 permeability; partial least squares; Molconn‐Z; quantitative structure–property relationship; Human; Caco-2 permeability; Digestive system; quantitative structure-property relationship; Gut; Permeation; Prediction; Permeability; Absorption; Genetic algorithm; Least squares method; Established cell line; Property structure relationship; Molconn-Z; Partial least squares; Tumor cell; Quantitative analysis