Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes - Abdelsamed, Hossam A.; Zebley, Caitlin C.; Nguyen, Hai; Rutishauser, Rachel L.; Fan, Yiping; Ghoneim, Hazem E.; Crawford, Jeremy Chase; Alfei, Francesca; Alli, Shanta; Ribeiro, Susan Pereira; Castellaw, Ashley H.; McGargill, Maureen A.; et al. (Nature immunology, 2020)
Keywords: 631/250/1619; 631/250/2152; 631/250/2502; 631/250/2520; 631/250/38; Adolescent; Adult; Animals; Autoantigens - immunology; Beta cells; Biomedical and Life Sciences; Biomedicine; CD8 antigen; CD8-Positive T-Lymphocytes - physiology; Cell differentiation; Cell Plasticity; Cells, Cultured; Chromatin; Diabetes; Diabetes mellitus (insulin dependent); Diabetes Mellitus, Type 1 - immunology; DNA Methylation; Epigenesis, Genetic; Epigenetics; Female; Flow Cytometry; Humans; Immunologic Memory; Immunology; Infectious Diseases; Insulin-Secreting Cells - immunology; Lymphocytes; Lymphocytes T; Lymphoid tissue; Male; Memory cells; Mice; Pancreas; Phenotypic plasticity; Pluripotent Stem Cells - physiology; Resource; Single-Cell Analysis; Stem cells; Transposase; Young Adult