Low expression of the CCL5 gene and low serum concentrations of CCL5 in severe invasive group a streptococcal disease - Kailankangas, V; Katayama, S; Gröndahl-Yli-Hannuksela, K; Vilhonen, J; Tervaniemi, MH; Rantakokko-Jalava, K; Seiskari, T; Lönnqvist, E; Kere, J; Oksi, J; Syrjänen, J; Vuopio, J (Infection, 2025)
Keywords: Adolescent; Adult; Biomarkers; Biomarkers - blood; blood serum; Chemokine CCL5 - blood; Chemokine CCL5 - genetics; Chemokines; Cytotoxicity; death; disease course; disease severity; Family Medicine; Female; Gene expression; Gene Expression Profiling; General Practice; genes; Humans; immunity; infection; Infectious Diseases; Intensive care; Internal Medicine; Knowledge representation; ligands; Low concentrations; Male; Medicine; Medicine & Public Health; Middle Aged; Severity of Illness Index; Streptococcal Infections - blood; Streptococcal Infections - genetics; Streptococcal Infections - immunology; Streptococcal Infections - microbiology; Streptococcus infections; Streptococcus pyogenes; transcriptome; Transcriptomes; transcriptomics; Young Adult; Streptococcus group A; Critical care; Sepsis; Streptococcal infections; Transcriptome