Point process models for sweat gland activation observed with noise

• Published in: Statistics in medicine Vol. 40; no. 8; pp. 2055 - 2072
• Main Authors: Kuronen, Mikko, Myllymäki, Mari, Loavenbruck, Adam, Särkkä, Aila
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 15.04.2021
• Subjects: Bayesian inference; Environmental; independent thinning; Matematik; Mathematical & Computational Biology; Mathematical sciences; Mathematics; Medical Informatics; Medical statistics; Medicine; Occupational Health; pattern; peripheral neuropathy; point; point pattern; Public; Research & Experimental; sequential point process; soft-core inhibition; Bayesian inference; peripheral neuropathy; sequential point process; soft-core inhibition; point pattern; independent thinning
• ISSN: 0277-6715; 1097-0258; 1097-0258
• DOI: 10.1002/sim.8891

The aim of this article is to construct spatial models for the activation of sweat glands for healthy subjects and subjects suffering from peripheral neuropathy by using videos of sweating recorded from the subjects. The sweat patterns are regarded as realizations of spatial point processes and two point process models for the sweat gland activation and two methods for inference are proposed. Several image analysis steps are needed to extract the point patterns from the videos and some incorrectly identified sweat gland locations may be present in the data. To take into account the errors, we either include an error term in the point process model or use an estimation procedure that is robust with respect to the errors.