Acellular dermal matrix graft with or without enamel matrix derivative for root coverage in smokers: a randomized clinical study

• Published in: Journal of clinical periodontology Vol. 39; no. 4; pp. 393 - 399
• Main Authors: B. Alves, Luciana, P. Costa, Priscila, de Souza, Sérgio Luís Scombatti, F. de Moraes Grisi, Márcio, B. Palioto, Daniela, Taba Jr, Mario, B. Novaes Jr, Arthur
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell Publishing Ltd 01.04.2012; Blackwell
• Subjects: acellular dermal matrix graft; Adult; Biological and medical sciences; Chi-Square Distribution; Collagen; dental enamel proteins; Dental Enamel Proteins - therapeutic use; Enamel; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Gingiva; gingival recession; Gingival Recession - drug therapy; Gingival Recession - surgery; Gingivoplasty - methods; Humans; Male; Medical sciences; Middle Aged; Non tumoral diseases; Otorhinolaryngology. Stomatology; Plastics; Roots; Single-Blind Method; Skin; Skin, Artificial; Smoking; Statistical analysis; Statistics, Nonparametric; Surgery; tobacco; Tooth root; Tooth enamel; Tobacco; gingival recession; Smoker; dental enamel proteins; acellular dermal matrix graft; Graft; Dentistry; Derm; Gingiva; Protein
• ISSN: 0303-6979; 1600-051X; 1600-051X
• DOI: 10.1111/j.1600-051X.2012.01851.x

Aim The aim of this randomized controlled clinical study was to compare the use of an acellular dermal matrix graft (ADMG) with or without the enamel matrix derivative (EMD) in smokers to evaluate which procedure would provide better root coverage. Material and Methods Nineteen smokers with bilateral Miller Class I or II gingival recessions ≥3 mm were selected. The test group was treated with an association of ADMG and EMD, and the control group with ADMG alone. Probing depth, relative clinical attachment level, gingival recession height, gingival recession width, keratinized tissue width and keratinized tissue thickness were evaluated before the surgeries and after 6 months. Wilcoxon test was used for the statistical analysis at significance level of 5%. Results No significant differences were found between groups in all parameters at baseline. The mean gain recession height between baseline and 6 months and the complete root coverage favored the test group (p = 0.042, p = 0.019 respectively). Conclusion Smoking may negatively affect the results achieved through periodontal plastic procedures; however, the association of ADMG and EMD is beneficial in the root coverage of gingival recessions in smokers, 6 months after the surgery.