Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea
As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestatio...
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| Published in | Journal of Korean medical science Vol. 35; no. 7; pp. e86 - 7 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
The Korean Academy of Medical Sciences
24.02.2020
대한의학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1011-8934 1598-6357 1598-6357 |
| DOI | 10.3346/jkms.2020.35.e86 |
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| Abstract | As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated. However, data on viral load kinetics in confirmed cases are lacking. Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown. This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV. |
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| AbstractList | As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world.
With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated. However, data on viral load kinetics in confirmed cases are lacking. Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown. This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV. KCI Citation Count: 140 As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated. However, data on viral load kinetics in confirmed cases are lacking. Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown. This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV. As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated. However, data on viral load kinetics in confirmed cases are lacking. Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown. This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV.As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated. However, data on viral load kinetics in confirmed cases are lacking. Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown. This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV. |
| Author | Kim, Yae-Jean Han, Myung-Guk Ko, Jae-Hoon Kim, Jin Yong Kim, Yeonjae Kim, Heui Man Chin, Bum Sik Chung, Yoon-Seok Kim, So Yeon Kim, Jeong-Min |
| AuthorAffiliation | 5 Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea 4 Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 1 Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea 2 Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 3 Department of Internal Medicine, National Medical Center, Seoul, Korea 6 Department of Laboratory Medicine, National Medical Center, Seoul, Korea |
| AuthorAffiliation_xml | – name: 3 Department of Internal Medicine, National Medical Center, Seoul, Korea – name: 2 Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea – name: 4 Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea – name: 1 Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea – name: 6 Department of Laboratory Medicine, National Medical Center, Seoul, Korea – name: 5 Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea |
| Author_xml | – sequence: 1 givenname: Jin Yong orcidid: 0000-0002-4306-1597 surname: Kim fullname: Kim, Jin Yong organization: Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea – sequence: 2 givenname: Jae-Hoon orcidid: 0000-0002-9490-6609 surname: Ko fullname: Ko, Jae-Hoon organization: Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea – sequence: 3 givenname: Yeonjae orcidid: 0000-0003-4144-9077 surname: Kim fullname: Kim, Yeonjae organization: Department of Internal Medicine, National Medical Center, Seoul, Korea – sequence: 4 givenname: Yae-Jean orcidid: 0000-0002-8367-3424 surname: Kim fullname: Kim, Yae-Jean organization: Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea – sequence: 5 givenname: Jeong-Min orcidid: 0000-0002-8240-0395 surname: Kim fullname: Kim, Jeong-Min organization: Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea – sequence: 6 givenname: Yoon-Seok orcidid: 0000-0003-4562-5533 surname: Chung fullname: Chung, Yoon-Seok organization: Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea – sequence: 7 givenname: Heui Man orcidid: 0000-0003-2908-6437 surname: Kim fullname: Kim, Heui Man organization: Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea – sequence: 8 givenname: Myung-Guk orcidid: 0000-0002-3543-1826 surname: Han fullname: Han, Myung-Guk organization: Division of Viral Diseases, Center for Laboratory Control of Infectious Diseases, Korea Centers for Disease Control & Prevention, Cheongju, Korea – sequence: 9 givenname: So Yeon orcidid: 0000-0003-1774-0382 surname: Kim fullname: Kim, So Yeon organization: Department of Laboratory Medicine, National Medical Center, Seoul, Korea – sequence: 10 givenname: Bum Sik orcidid: 0000-0003-3021-1434 surname: Chin fullname: Chin, Bum Sik organization: Department of Internal Medicine, National Medical Center, Seoul, Korea |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32080991$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002558175$$DAccess content in National Research Foundation of Korea (NRF) |
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| Cites_doi | 10.3343/alm.2017.37.1.81 10.1056/NEJMoa2001316 10.1016/S0140-6736(03)13412-5 10.3346/jkms.2020.35.e61 10.2807/1560-7917.ES.2020.25.3.2000045 |
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| Title | Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea |
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