Clinical Outcomes of Silk Patch in Acute Tympanic Membrane Perforation
The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP). The closure rate, otorrhea rate, and closure time in all patients and the closure tim...
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| Published in | Clinical and experimental otorhinolaryngology Vol. 8; no. 2; pp. 117 - 122 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
Korean Society of Otorhinolaryngology-Head and Neck Surgery
01.06.2015
대한이비인후과학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1976-8710 2005-0720 2005-0720 |
| DOI | 10.3342/ceo.2015.8.2.117 |
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| Abstract | The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP).
The closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups.
Demographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037).
The silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation. |
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| AbstractList | The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP).OBJECTIVESThe silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP).The closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups.METHODSThe closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups.Demographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037).RESULTSDemographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037).The silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation.CONCLUSIONThe silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation. ObjectivesThe silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP).MethodsThe closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups.ResultsDemographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037).ConclusionThe silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation. Objectives. The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP). Methods. The closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups. Results. Demographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037). Conclusion. The silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation. KCI Citation Count: 12 The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP). The closure rate, otorrhea rate, and closure time in all patients and the closure time in successful patients were compared between the paper patch and silk patch groups. Demographic data (gender, site, age, traumatic duration, preoperative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rate and otorrhea rate were not significantly different between the two groups. However, the closure time was different between the two groups (closure time of all patients, P=0.031; closure time of successful patients, P=0.037). The silk patch which has transparent, elastic, adhesive, and hyper-keratinizing properties results in a more efficient closure time than the paper patch in the treatment of TTMP patients. We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation. |
| Author | Lee, Joong Seob Lee, Hae Ran Park, Chan Hum Lee, Jun Ho Kim, Dong-Kyu |
| AuthorAffiliation | 1 Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea 3 Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea 2 Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea |
| AuthorAffiliation_xml | – name: 2 Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea – name: 3 Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea – name: 1 Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea |
| Author_xml | – sequence: 1 givenname: Jun Ho surname: Lee fullname: Lee, Jun Ho organization: Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea., Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea – sequence: 2 givenname: Joong Seob surname: Lee fullname: Lee, Joong Seob organization: Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea., Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea – sequence: 3 givenname: Dong-Kyu surname: Kim fullname: Kim, Dong-Kyu organization: Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea., Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea – sequence: 4 givenname: Chan Hum surname: Park fullname: Park, Chan Hum organization: Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea., Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Korea – sequence: 5 givenname: Hae Ran surname: Lee fullname: Lee, Hae Ran organization: Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea |
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| Cites_doi | 10.1089/ten.teb.2012.0389 10.1016/j.otohns.2009.06.746 10.1016/j.biomaterials.2004.02.047 10.1002/lary.23940 10.1089/ten.tea.2012.0053 10.4103/1117-1936.177397 10.1089/ten.tea.2009.0476 10.1016/j.biomaterials.2004.09.020 10.1017/S0022215100121723 10.1177/0194599811409836 10.1586/erd.09.47 10.1002/jbm.a.33308 10.1111/j.1749-4486.2008.01764.x 10.1111/j.1524-475X.2009.00565.x 10.1016/j.biomaterials.2007.08.017 10.1016/S0142-9612(02)00353-8 10.1111/j.1749-4486.2008.01823.x |
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| Keywords | Silk Fibroins Tympanic Membrane Perforation Ear, Middle |
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| References | da Lilly-Tariah (10.3342/ceo.2015.8.2.117_ref1) 2007; 14 Altman (10.3342/ceo.2015.8.2.117_ref16) 2003; 24 Shen (10.3342/ceo.2015.8.2.117_ref6) 2013; 123 Kim (10.3342/ceo.2015.8.2.117_ref8) 2010; 18 Teh (10.3342/ceo.2015.8.2.117_ref4) 2013; 19 Lee (10.3342/ceo.2015.8.2.117_ref7) 2012; 100 Mori (10.3342/ceo.2015.8.2.117_ref11) 2000; 74 Meinel (10.3342/ceo.2015.8.2.117_ref13) 2005; 26 Park (10.3342/ceo.2015.8.2.117_ref9) 2011; 145 Saliba (10.3342/ceo.2015.8.2.117_ref10) 2008; 33 Levin (10.3342/ceo.2015.8.2.117_ref17) 2010; 142 Shen (10.3342/ceo.2015.8.2.117_ref18) 2013; 19 Mauney (10.3342/ceo.2015.8.2.117_ref14) 2007; 28 Horan (10.3342/ceo.2015.8.2.117_ref12) 2005; 26 Levin (10.3342/ceo.2015.8.2.117_ref5) 2009; 6 Kim (10.3342/ceo.2015.8.2.117_ref15) 2010; 16 Kristensen (10.3342/ceo.2015.8.2.117_ref3) 1992; 106 Orji (10.3342/ceo.2015.8.2.117_ref2) 2008; 33 23031158 - Tissue Eng Part B Rev. 2013 Apr;19(2):116-32 1487657 - J Laryngol Otol. 1992 Dec;106(12):1037-50 18983374 - Clin Otolaryngol. 2008 Oct;33(5):420-6 19691425 - Tissue Eng Part A. 2010 Jan;16(1):225-32 20082686 - Wound Repair Regen. 2010 Jan-Feb;18(1):132-8 17599109 - Niger Postgrad Med J. 2007 Jun;14(2):121-4 12423595 - Biomaterials. 2003 Feb;24(3):401-16 21593464 - Otolaryngol Head Neck Surg. 2011 Oct;145(4):581-5 11763506 - J Biotechnol. 2000 Aug;74(2):95-103 23092139 - Tissue Eng Part A. 2013 Mar;19(5-6):657-68 23536496 - Laryngoscope. 2013 Aug;123(8):1976-82 19126140 - Clin Otolaryngol. 2008 Dec;33(6):610-4 15621227 - Biomaterials. 2005 Jun;26(17):3385-93 22581612 - J Biomed Mater Res A. 2012 Aug;100(8):2018-26 19911876 - Expert Rev Med Devices. 2009 Nov;6(6):653-64 15207461 - Biomaterials. 2005 Jan;26(2):147-55 20176279 - Otolaryngol Head Neck Surg. 2010 Mar;142(3 Suppl 1):S33-5 17765303 - Biomaterials. 2007 Dec;28(35):5280-90 |
| References_xml | – volume: 19 start-page: 116 issue: 2 year: 2013 ident: 10.3342/ceo.2015.8.2.117_ref4 publication-title: Tissue Eng Part B Rev doi: 10.1089/ten.teb.2012.0389 – volume: 74 start-page: 95 issue: 2 year: 2000 ident: 10.3342/ceo.2015.8.2.117_ref11 publication-title: J Biotechnol – volume: 142 start-page: S33 issue: 3 Suppl 1 year: 2010 ident: 10.3342/ceo.2015.8.2.117_ref17 publication-title: Otolaryngol Head Neck Surg doi: 10.1016/j.otohns.2009.06.746 – volume: 26 start-page: 147 issue: 2 year: 2005 ident: 10.3342/ceo.2015.8.2.117_ref13 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2004.02.047 – volume: 123 start-page: 1976 issue: 8 year: 2013 ident: 10.3342/ceo.2015.8.2.117_ref6 publication-title: Laryngoscope doi: 10.1002/lary.23940 – volume: 19 start-page: 657 issue: 5-6 year: 2013 ident: 10.3342/ceo.2015.8.2.117_ref18 publication-title: Tissue Eng Part A doi: 10.1089/ten.tea.2012.0053 – volume: 14 start-page: 121 issue: 2 year: 2007 ident: 10.3342/ceo.2015.8.2.117_ref1 publication-title: Niger Postgrad Med J doi: 10.4103/1117-1936.177397 – volume: 16 start-page: 225 issue: 1 year: 2010 ident: 10.3342/ceo.2015.8.2.117_ref15 publication-title: Tissue Eng Part A doi: 10.1089/ten.tea.2009.0476 – volume: 26 start-page: 3385 issue: 17 year: 2005 ident: 10.3342/ceo.2015.8.2.117_ref12 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2004.09.020 – volume: 106 start-page: 1037 issue: 12 year: 1992 ident: 10.3342/ceo.2015.8.2.117_ref3 publication-title: J Laryngol Otol doi: 10.1017/S0022215100121723 – volume: 145 start-page: 581 issue: 4 year: 2011 ident: 10.3342/ceo.2015.8.2.117_ref9 publication-title: Otolaryngol Head Neck Surg doi: 10.1177/0194599811409836 – volume: 6 start-page: 653 issue: 6 year: 2009 ident: 10.3342/ceo.2015.8.2.117_ref5 publication-title: Expert Rev Med Devices doi: 10.1586/erd.09.47 – volume: 100 start-page: 2018 issue: 8 year: 2012 ident: 10.3342/ceo.2015.8.2.117_ref7 publication-title: J Biomed Mater Res A doi: 10.1002/jbm.a.33308 – volume: 33 start-page: 420 issue: 5 year: 2008 ident: 10.3342/ceo.2015.8.2.117_ref2 publication-title: Clin Otolaryngol doi: 10.1111/j.1749-4486.2008.01764.x – volume: 18 start-page: 132 issue: 1 year: 2010 ident: 10.3342/ceo.2015.8.2.117_ref8 publication-title: Wound Repair Regen doi: 10.1111/j.1524-475X.2009.00565.x – volume: 28 start-page: 5280 issue: 35 year: 2007 ident: 10.3342/ceo.2015.8.2.117_ref14 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2007.08.017 – volume: 24 start-page: 401 issue: 3 year: 2003 ident: 10.3342/ceo.2015.8.2.117_ref16 publication-title: Biomaterials doi: 10.1016/S0142-9612(02)00353-8 – volume: 33 start-page: 610 issue: 6 year: 2008 ident: 10.3342/ceo.2015.8.2.117_ref10 publication-title: Clin Otolaryngol doi: 10.1111/j.1749-4486.2008.01823.x – reference: 11763506 - J Biotechnol. 2000 Aug;74(2):95-103 – reference: 19126140 - Clin Otolaryngol. 2008 Dec;33(6):610-4 – reference: 15207461 - Biomaterials. 2005 Jan;26(2):147-55 – reference: 1487657 - J Laryngol Otol. 1992 Dec;106(12):1037-50 – reference: 12423595 - Biomaterials. 2003 Feb;24(3):401-16 – reference: 20176279 - Otolaryngol Head Neck Surg. 2010 Mar;142(3 Suppl 1):S33-5 – reference: 23536496 - Laryngoscope. 2013 Aug;123(8):1976-82 – reference: 19691425 - Tissue Eng Part A. 2010 Jan;16(1):225-32 – reference: 23092139 - Tissue Eng Part A. 2013 Mar;19(5-6):657-68 – reference: 20082686 - Wound Repair Regen. 2010 Jan-Feb;18(1):132-8 – reference: 22581612 - J Biomed Mater Res A. 2012 Aug;100(8):2018-26 – reference: 17599109 - Niger Postgrad Med J. 2007 Jun;14(2):121-4 – reference: 15621227 - Biomaterials. 2005 Jun;26(17):3385-93 – reference: 18983374 - Clin Otolaryngol. 2008 Oct;33(5):420-6 – reference: 19911876 - Expert Rev Med Devices. 2009 Nov;6(6):653-64 – reference: 21593464 - Otolaryngol Head Neck Surg. 2011 Oct;145(4):581-5 – reference: 23031158 - Tissue Eng Part B Rev. 2013 Apr;19(2):116-32 – reference: 17765303 - Biomaterials. 2007 Dec;28(35):5280-90 |
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| Snippet | The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in... ObjectivesThe silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch... Objectives. The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk... |
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| StartPage | 117 |
| SubjectTerms | Ear, Middle Fibroins Original Silk Tympanic Membrane Perforation 이비인후과학 |
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| Title | Clinical Outcomes of Silk Patch in Acute Tympanic Membrane Perforation |
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