Predictors of severe pain during insertion of the levonorgestrel 52 mg intrauterine system among nulligravid women

To identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women. We performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed fac...

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Published inContraception (Stoneham) Vol. 102; no. 4; pp. 267 - 269
Main Authors Ferreira, Letícia Sanchez, de Nadai, Mariane Nunes, Poli-Neto, Omero B., Franceschini, Silvio A., Juliato, Cássia R.T., Monteiro, Ilza Maria U., Bahamondes, Luis, Vieira, Carolina Sales
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2020
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ISSN0010-7824
1879-0518
1879-0518
DOI10.1016/j.contraception.2020.07.004

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Abstract To identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women. We performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed factors associated with severe pain (visual analog scale pain score ≥7) immediately after insertion using bivariate and multiple regression analyses. Overall, 137/300 (45.7%) subjects reported severe pain. In multiple regression analysis, only intracervical anesthesia [RR 0.55, 95% CI 0.37–0.80] and a history of dysmenorrhea [RR 1.36, 95% CI 1.08–1.72)] were associated with severe pain. Among nulligravid women, a history of dysmenorrhea increases, and intracervical block decreases severe pain during levonorgestrel IUS insertion. Dysmenorrhea increases the risk of severe pain at levonorgestrel intrauterine system insertion, while receiving an intracervical lidocaine block decreases this risk. This information can be useful for counseling women prior to device placement and for selecting candidates who may particularly benefit from interventions to reduce pain.
AbstractList To identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women.OBJECTIVETo identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women.We performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed factors associated with severe pain (visual analog scale pain score ≥7) immediately after insertion using bivariate and multiple regression analyses.STUDY DESIGNWe performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed factors associated with severe pain (visual analog scale pain score ≥7) immediately after insertion using bivariate and multiple regression analyses.Overall, 137/300 (45.7%) subjects reported severe pain. In multiple regression analysis, only intracervical anesthesia [RR 0.55, 95% CI 0.37-0.80] and a history of dysmenorrhea [RR 1.36, 95% CI 1.08-1.72)] were associated with severe pain.RESULTSOverall, 137/300 (45.7%) subjects reported severe pain. In multiple regression analysis, only intracervical anesthesia [RR 0.55, 95% CI 0.37-0.80] and a history of dysmenorrhea [RR 1.36, 95% CI 1.08-1.72)] were associated with severe pain.Among nulligravid women, a history of dysmenorrhea increases, and intracervical block decreases severe pain during levonorgestrel IUS insertion.CONCLUSIONSAmong nulligravid women, a history of dysmenorrhea increases, and intracervical block decreases severe pain during levonorgestrel IUS insertion.Dysmenorrhea increases the risk of severe pain at levonorgestrel intrauterine system insertion, while receiving an intracervical lidocaine block decreases this risk. This information can be useful for counseling women prior to device placement and for selecting candidates who may particularly benefit from interventions to reduce pain.IMPLICATIONSDysmenorrhea increases the risk of severe pain at levonorgestrel intrauterine system insertion, while receiving an intracervical lidocaine block decreases this risk. This information can be useful for counseling women prior to device placement and for selecting candidates who may particularly benefit from interventions to reduce pain.
To identify sociodemographic and clinical variables associated with severe pain with levonorgestrel 52 mg intrauterine system (IUS) placement among nulligravid women. We performed a secondary analysis of a randomized trial that evaluated intracervical anesthesia before IUS insertion. We assessed factors associated with severe pain (visual analog scale pain score ≥7) immediately after insertion using bivariate and multiple regression analyses. Overall, 137/300 (45.7%) subjects reported severe pain. In multiple regression analysis, only intracervical anesthesia [RR 0.55, 95% CI 0.37-0.80] and a history of dysmenorrhea [RR 1.36, 95% CI 1.08-1.72)] were associated with severe pain. Among nulligravid women, a history of dysmenorrhea increases, and intracervical block decreases severe pain during levonorgestrel IUS insertion. Dysmenorrhea increases the risk of severe pain at levonorgestrel intrauterine system insertion, while receiving an intracervical lidocaine block decreases this risk. This information can be useful for counseling women prior to device placement and for selecting candidates who may particularly benefit from interventions to reduce pain.
Author Bahamondes, Luis
Monteiro, Ilza Maria U.
Ferreira, Letícia Sanchez
Franceschini, Silvio A.
Juliato, Cássia R.T.
Vieira, Carolina Sales
de Nadai, Mariane Nunes
Poli-Neto, Omero B.
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Cites_doi 10.1016/j.contraception.2015.05.009
10.1097/AOG.0000000000000362
10.1002/ejp.556
10.1016/j.ijgo.2014.11.004
10.3109/01443615.2013.868424
10.1016/j.ajem.2018.01.008
10.1016/j.ajog.2018.11.1085
10.1093/humrep/deu233
10.1016/j.contraception.2013.07.009
10.1016/0010-7824(86)90057-0
10.1097/AOG.0000000000002242
10.1016/j.contraception.2014.11.012
10.1097/AOG.0000000000002790
10.1016/j.ajog.2006.08.022
10.1016/j.contraception.2012.01.005
10.1016/S0304-3959(00)00459-0
10.1016/j.contraception.2014.11.006
10.1016/j.ajog.2019.09.013
10.1016/j.pain.2011.03.029
10.1136/postgradmedj-2016-134247
10.1016/j.ajog.2017.10.017
10.1590/S0034-89101995000500004
10.1016/j.contraception.2012.10.015
10.2147/JPR.S143512
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Issue 4
Keywords Nulligravid women
Contraception
Levonorgestrel intrauterine system
Pain
Language English
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References Botega, Bio, Zomignani, Garcia, Pereira (b0085) 1995; 29
Castro, Franceschini, Poli-Neto, Ferriani (b0025) 2014; 29
De Nadai, Poli-Neto, Franceschini, Yamaguti, Monteiro, Troncon (b0055) 2020; 222
Doty, MacIsaac (b0095) 2015; 92
Chen, Kwekkeboom, Ward (b0130) 2015; 19
Karcioglu, Topacoglu, Dikme, Dikme (b0075) 2018; 36
Mody, Farala, Jimenez, Nishikawa, Ngo (b0065) 2018; 132
World Health Organization (b0070) 2015
Jensen, Smith, Ehde, Robinsin (b0080) 2001; 91
Vincent, Warnaby, Stagg, Moore, Kennedy, Tracey (b0120) 2011; 152
da Silva-Filho, Lira, Rocha, Carneiro (b0005) 2017; 93
Allen, Carey, Raker, Goyal, Matteson (b0020) 2014; 34
Maguire, Davis, Rosario Tejeda, Westhoff (b0045) 2012; 86
Akers, Steinway, Sonalkar, Perriera, Schreiber, Harding (b0060) 2017; 130
Wiebe (b0105) 2015; 129
Bednarek, Creinin, Reeves, Cwiak, Espey, Jensen (b0090) 2015; 91
Payne, Rapkin, Seidman, Zeltzer, Tsao (b0125) 2017; 10
Dina, Peipert, Zhao, Peipert (b0015) 2018; 218
Conti, Lerma, Schneyer, Hastings, Blumenthal, Shaw (b0040) 2019; 220
Santos, Bahamondes, Hidalgo, Atti, Bahamondes, Monteiro (b0110) 2013; 88
Morrow, Naumburg (b0115) 2009; 36
Hubacher, Spector, Monteith, Chen, Hart (b0010) 2015; 91
Allen, Raker, Goyal (b0030) 2013; 88
Chi, Galich, Tauber, Wilkens, Waszak, Siemens (b0035) 1986; 34
Kaislasuo, Heikinheimo, Lähteenmäki, Suhonen (b0050) 2014; 124
Hubacher, Reyes, Lillo, Zepeda, Chen, Croxatto (b0100) 2006; 195
Chi (10.1016/j.contraception.2020.07.004_b0035) 1986; 34
Doty (10.1016/j.contraception.2020.07.004_b0095) 2015; 92
Hubacher (10.1016/j.contraception.2020.07.004_b0100) 2006; 195
Hubacher (10.1016/j.contraception.2020.07.004_b0010) 2015; 91
Botega (10.1016/j.contraception.2020.07.004_b0085) 1995; 29
Maguire (10.1016/j.contraception.2020.07.004_b0045) 2012; 86
Mody (10.1016/j.contraception.2020.07.004_b0065) 2018; 132
Jensen (10.1016/j.contraception.2020.07.004_b0080) 2001; 91
Allen (10.1016/j.contraception.2020.07.004_b0030) 2013; 88
World Health Organization (10.1016/j.contraception.2020.07.004_b0070) 2015
Kaislasuo (10.1016/j.contraception.2020.07.004_b0050) 2014; 124
Santos (10.1016/j.contraception.2020.07.004_b0110) 2013; 88
Conti (10.1016/j.contraception.2020.07.004_b0040) 2019; 220
Castro (10.1016/j.contraception.2020.07.004_b0025) 2014; 29
De Nadai (10.1016/j.contraception.2020.07.004_b0055) 2020; 222
Morrow (10.1016/j.contraception.2020.07.004_b0115) 2009; 36
Payne (10.1016/j.contraception.2020.07.004_b0125) 2017; 10
Chen (10.1016/j.contraception.2020.07.004_b0130) 2015; 19
da Silva-Filho (10.1016/j.contraception.2020.07.004_b0005) 2017; 93
Akers (10.1016/j.contraception.2020.07.004_b0060) 2017; 130
Dina (10.1016/j.contraception.2020.07.004_b0015) 2018; 218
Allen (10.1016/j.contraception.2020.07.004_b0020) 2014; 34
Wiebe (10.1016/j.contraception.2020.07.004_b0105) 2015; 129
Karcioglu (10.1016/j.contraception.2020.07.004_b0075) 2018; 36
Vincent (10.1016/j.contraception.2020.07.004_b0120) 2011; 152
Bednarek (10.1016/j.contraception.2020.07.004_b0090) 2015; 91
References_xml – volume: 91
  start-page: 193
  year: 2015
  end-page: 197
  ident: b0090
  article-title: Prophylactic ibuprofen does not improve pain with IUD insertion: a randomized trial
  publication-title: Contraception
– volume: 36
  start-page: 707
  year: 2018
  end-page: 714
  ident: b0075
  article-title: A systematic review of the pain scales in adults: Which to use?
  publication-title: Am J Emerg Med
– volume: 34
  start-page: 263
  year: 2014
  end-page: 267
  ident: b0020
  article-title: A prospective cohort study of pain with intrauterine device insertion among women with and without vaginal deliveries
  publication-title: J Obstet Gynaecol
– volume: 129
  start-page: 172
  year: 2015
  ident: b0105
  article-title: A comparison of the insertion pain associated with three different types of intrauterine device
  publication-title: Int J Gynaecol Obstet
– volume: 220
  start-page: 177.e1
  year: 2019
  end-page: 177.e7
  ident: b0040
  article-title: Self-administered vaginal lidocaine gel for pain management with intrauterine device insertion: a blinded, randomized controlled trial
  publication-title: Am J Obstet Gynecol
– volume: 222
  start-page: 245.e1
  year: 2020
  end-page: 245.e10
  ident: b0055
  article-title: Intracervical block for levonorgestrel-releasing intrauterine system placement among nulligravid women: a randomized double-blind controlled trial
  publication-title: Am J Obstet Gynecol
– volume: 152
  start-page: 1966
  year: 2011
  end-page: 1975
  ident: b0120
  article-title: Dysmenorrhoea is associated with central changes in otherwise healthy women
  publication-title: Pain
– volume: 91
  start-page: 185
  year: 2015
  end-page: 192
  ident: b0010
  article-title: Rationale and enrollment results for a partially randomized patient preference trial to compare continuation rates of short-acting and long-acting reversible contraception
  publication-title: Contraception
– volume: 88
  start-page: 730
  year: 2013
  end-page: 736
  ident: b0030
  article-title: Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial
  publication-title: Contraception
– volume: 29
  start-page: 359
  year: 1995
  end-page: 363
  ident: b0085
  article-title: Mood disorders among medical in-patients: a validation study of the hospital anxiety and depression scale (HAD)
  publication-title: Rev Saúde Pública
– volume: 10
  start-page: 2233
  year: 2017
  end-page: 2246
  ident: b0125
  article-title: Experimental and procedural pain responses in primary dysmenorrhea: a systematic review
  publication-title: J Pain Res
– volume: 93
  start-page: 376
  year: 2017
  end-page: 381
  ident: b0005
  article-title: Barriers and myths that limit the use of intrauterine contraception in nulliparous women: a survey of Brazilian gynaecologists
  publication-title: Postgrad Med J
– volume: 29
  start-page: 2439
  year: 2014
  end-page: 2445
  ident: b0025
  article-title: Silva de Sá MF, Vieira CS. Effect of intracervical anesthesia on pain associated with the insertion of the levonorgestrel-releasing intrauterine system in women without previous vaginal delivery: a RCT
  publication-title: Hum Reprod
– volume: 124
  start-page: 345
  year: 2014
  end-page: 353
  ident: b0050
  article-title: Predicting painful or difficult intrauterine device insertion in nulligravid women
  publication-title: Obstet Gynecol
– volume: 218
  start-page: 236.e1
  year: 2018
  end-page: 236.e9
  ident: b0015
  article-title: Anticipated pain as a predictor of discomfort with intrauterine device placement
  publication-title: Am J Obstet Gynecol
– volume: 92
  start-page: 567
  year: 2015
  end-page: 571
  ident: b0095
  article-title: Effect of an atraumatic vulsellum versus a single-tooth tenaculum on pain perception during intrauterine device insertion: a randomized controlled trial
  publication-title: Contraception
– volume: 130
  start-page: 795
  year: 2017
  end-page: 802
  ident: b0060
  article-title: Reducing pain during intrauterine device insertion: a randomized controlled trial in adolescents and young women
  publication-title: Obstet Gynecol
– volume: 19
  start-page: 377
  year: 2015
  end-page: 391
  ident: b0130
  article-title: Self-report pain and symptom measures for primary dysmenorrhoea: a critical review
  publication-title: Eur J Pain
– year: 2015
  ident: b0070
  article-title: WHO Medical eligibility criteria for contraceptive use
– volume: 34
  start-page: 483
  year: 1986
  end-page: 495
  ident: b0035
  article-title: Severe pain at interval IUD insertion: a case-control analysis of patient risk factors
  publication-title: Contraception
– volume: 132
  start-page: 575
  year: 2018
  end-page: 582
  ident: b0065
  article-title: Paracervical block for intrauterine device placement among nulliparous women: A randomized controlled trial
  publication-title: Obstet Gynecol
– volume: 86
  start-page: 214
  year: 2012
  end-page: 219
  ident: b0045
  article-title: Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial
  publication-title: Contraception
– volume: 36
  start-page: vii
  year: 2009
  ident: b0115
  article-title: Dysmenorrhea
  publication-title: Prim Care
– volume: 91
  start-page: 317
  year: 2001
  end-page: 322
  ident: b0080
  article-title: Pain site and the effects of amputation pain: further clarification of the meaning of mild, moderate, and severe pain
  publication-title: Pain
– volume: 195
  start-page: 1272
  year: 2006
  end-page: 1277
  ident: b0100
  article-title: Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen
  publication-title: Am J Obstet Gynecol
– volume: 88
  start-page: 164
  year: 2013
  end-page: 168
  ident: b0110
  article-title: Pain at insertion of the levonorgestrel-releasing intrauterine system in nulligravida and parous women with and without cesarean section
  publication-title: Contraception
– volume: 92
  start-page: 567
  year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0095
  article-title: Effect of an atraumatic vulsellum versus a single-tooth tenaculum on pain perception during intrauterine device insertion: a randomized controlled trial
  publication-title: Contraception
  doi: 10.1016/j.contraception.2015.05.009
– volume: 124
  start-page: 345
  year: 2014
  ident: 10.1016/j.contraception.2020.07.004_b0050
  article-title: Predicting painful or difficult intrauterine device insertion in nulligravid women
  publication-title: Obstet Gynecol
  doi: 10.1097/AOG.0000000000000362
– volume: 19
  start-page: 377
  year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0130
  article-title: Self-report pain and symptom measures for primary dysmenorrhoea: a critical review
  publication-title: Eur J Pain
  doi: 10.1002/ejp.556
– volume: 129
  start-page: 172
  year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0105
  article-title: A comparison of the insertion pain associated with three different types of intrauterine device
  publication-title: Int J Gynaecol Obstet
  doi: 10.1016/j.ijgo.2014.11.004
– volume: 34
  start-page: 263
  year: 2014
  ident: 10.1016/j.contraception.2020.07.004_b0020
  article-title: A prospective cohort study of pain with intrauterine device insertion among women with and without vaginal deliveries
  publication-title: J Obstet Gynaecol
  doi: 10.3109/01443615.2013.868424
– volume: 36
  start-page: 707
  year: 2018
  ident: 10.1016/j.contraception.2020.07.004_b0075
  article-title: A systematic review of the pain scales in adults: Which to use?
  publication-title: Am J Emerg Med
  doi: 10.1016/j.ajem.2018.01.008
– volume: 220
  start-page: 177.e1
  year: 2019
  ident: 10.1016/j.contraception.2020.07.004_b0040
  article-title: Self-administered vaginal lidocaine gel for pain management with intrauterine device insertion: a blinded, randomized controlled trial
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2018.11.1085
– volume: 29
  start-page: 2439
  year: 2014
  ident: 10.1016/j.contraception.2020.07.004_b0025
  article-title: Silva de Sá MF, Vieira CS. Effect of intracervical anesthesia on pain associated with the insertion of the levonorgestrel-releasing intrauterine system in women without previous vaginal delivery: a RCT
  publication-title: Hum Reprod
  doi: 10.1093/humrep/deu233
– volume: 88
  start-page: 730
  year: 2013
  ident: 10.1016/j.contraception.2020.07.004_b0030
  article-title: Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial
  publication-title: Contraception
  doi: 10.1016/j.contraception.2013.07.009
– volume: 34
  start-page: 483
  year: 1986
  ident: 10.1016/j.contraception.2020.07.004_b0035
  article-title: Severe pain at interval IUD insertion: a case-control analysis of patient risk factors
  publication-title: Contraception
  doi: 10.1016/0010-7824(86)90057-0
– volume: 130
  start-page: 795
  year: 2017
  ident: 10.1016/j.contraception.2020.07.004_b0060
  article-title: Reducing pain during intrauterine device insertion: a randomized controlled trial in adolescents and young women
  publication-title: Obstet Gynecol
  doi: 10.1097/AOG.0000000000002242
– volume: 91
  start-page: 193
  year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0090
  article-title: Prophylactic ibuprofen does not improve pain with IUD insertion: a randomized trial
  publication-title: Contraception
  doi: 10.1016/j.contraception.2014.11.012
– volume: 132
  start-page: 575
  year: 2018
  ident: 10.1016/j.contraception.2020.07.004_b0065
  article-title: Paracervical block for intrauterine device placement among nulliparous women: A randomized controlled trial
  publication-title: Obstet Gynecol
  doi: 10.1097/AOG.0000000000002790
– year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0070
– volume: 195
  start-page: 1272
  year: 2006
  ident: 10.1016/j.contraception.2020.07.004_b0100
  article-title: Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2006.08.022
– volume: 86
  start-page: 214
  year: 2012
  ident: 10.1016/j.contraception.2020.07.004_b0045
  article-title: Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial
  publication-title: Contraception
  doi: 10.1016/j.contraception.2012.01.005
– volume: 91
  start-page: 317
  year: 2001
  ident: 10.1016/j.contraception.2020.07.004_b0080
  article-title: Pain site and the effects of amputation pain: further clarification of the meaning of mild, moderate, and severe pain
  publication-title: Pain
  doi: 10.1016/S0304-3959(00)00459-0
– volume: 36
  start-page: vii
  issue: 19–32
  year: 2009
  ident: 10.1016/j.contraception.2020.07.004_b0115
  article-title: Dysmenorrhea
  publication-title: Prim Care
– volume: 91
  start-page: 185
  year: 2015
  ident: 10.1016/j.contraception.2020.07.004_b0010
  article-title: Rationale and enrollment results for a partially randomized patient preference trial to compare continuation rates of short-acting and long-acting reversible contraception
  publication-title: Contraception
  doi: 10.1016/j.contraception.2014.11.006
– volume: 222
  start-page: 245.e1
  year: 2020
  ident: 10.1016/j.contraception.2020.07.004_b0055
  article-title: Intracervical block for levonorgestrel-releasing intrauterine system placement among nulligravid women: a randomized double-blind controlled trial
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2019.09.013
– volume: 152
  start-page: 1966
  year: 2011
  ident: 10.1016/j.contraception.2020.07.004_b0120
  article-title: Dysmenorrhoea is associated with central changes in otherwise healthy women
  publication-title: Pain
  doi: 10.1016/j.pain.2011.03.029
– volume: 93
  start-page: 376
  year: 2017
  ident: 10.1016/j.contraception.2020.07.004_b0005
  article-title: Barriers and myths that limit the use of intrauterine contraception in nulliparous women: a survey of Brazilian gynaecologists
  publication-title: Postgrad Med J
  doi: 10.1136/postgradmedj-2016-134247
– volume: 218
  start-page: 236.e1
  year: 2018
  ident: 10.1016/j.contraception.2020.07.004_b0015
  article-title: Anticipated pain as a predictor of discomfort with intrauterine device placement
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2017.10.017
– volume: 29
  start-page: 359
  year: 1995
  ident: 10.1016/j.contraception.2020.07.004_b0085
  article-title: Mood disorders among medical in-patients: a validation study of the hospital anxiety and depression scale (HAD)
  publication-title: Rev Saúde Pública
  doi: 10.1590/S0034-89101995000500004
– volume: 88
  start-page: 164
  year: 2013
  ident: 10.1016/j.contraception.2020.07.004_b0110
  article-title: Pain at insertion of the levonorgestrel-releasing intrauterine system in nulligravida and parous women with and without cesarean section
  publication-title: Contraception
  doi: 10.1016/j.contraception.2012.10.015
– volume: 10
  start-page: 2233
  year: 2017
  ident: 10.1016/j.contraception.2020.07.004_b0125
  article-title: Experimental and procedural pain responses in primary dysmenorrhea: a systematic review
  publication-title: J Pain Res
  doi: 10.2147/JPR.S143512
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SubjectTerms Contraception
Levonorgestrel intrauterine system
Nulligravid women
Pain
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Title Predictors of severe pain during insertion of the levonorgestrel 52 mg intrauterine system among nulligravid women
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