PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation - Wimmer, Isabella; Tietz, Silvia; Nishihara, Hideaki; Deutsch, Urban; Sallusto, Federica; Gosselet, Fabien; Lyck, Ruth; Muller, William A.; Lassmann, Hans; Engelhardt, Britta (Frontiers in immunology, 2019)
Keywords: Adaptive immunology; Adult; Animals; blood-brain barrier; Blood-Brain Barrier - immunology; Cells, Cultured; endothelial junctions; Endothelium, Vascular - metabolism; Endothelium, Vascular - pathology; Female; Gray Matter - immunology; Humans; Immunology; Life Sciences; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; multiple sclerosis; Multiple Sclerosis - immunology; Neurobiology; Neurogenic Inflammation; Neurons and Cognition; Paracrine Communication; PECAM-1; Platelet Endothelial Cell Adhesion Molecule-1 - genetics; Platelet Endothelial Cell Adhesion Molecule-1 - metabolism; T-cell diapedesis; T-Lymphocyte Subsets - immunology; Th1 Cells - immunology; Transendothelial and Transepithelial Migration; Up-Regulation; vascular permeability; White Matter - immunology; blood-brain barrier; PECAM-1; T-cell diapedesis; endothelial junctions; vascular permeability; multiple sclerosis