Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation - Song, Yan; Botvinnik, Olga B.; Lovci, Michael T.; Kakaradov, Boyko; Liu, Patrick; Xu, Jia L.; Yeo, Gene W. (Molecular cell, 2017)
Keywords: Algorithms; Alternative Splicing; Bayes Theorem; Bayesian theory; bimodality; Cell Line; Computer Simulation; differentiation; Evolution, Molecular; exons; gene expression; Gene Expression Regulation, Developmental; homeostasis; Humans; Kinetics; Male; modality; Models, Genetic; Nerve Tissue Proteins - biosynthesis; Nerve Tissue Proteins - genetics; Neural Stem Cells - metabolism; Neurogenesis; neuron; neurons; Neurons - metabolism; Phenotype; Pluripotent Stem Cells - metabolism; post-transcription; RNA processing; RNA, Messenger - genetics; RNA, Messenger - metabolism; single cell; Single-Cell Analysis; stem cells; stem cells; single cell; differentiation; modality; alternative splicing; post-transcription; neuron; bimodality; RNA processing