Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma - Kawano, Hiroyuki; Saeki, Hiroshi; Kitao, Hiroyuki; Tsuda, Yasuo; Otsu, Hajime; Ando, Koji; Ito, Shuhei; Egashira, Akinori; Oki, Eiji; Morita, Masaru; Oda, Yoshinao; Maehara, Yoshihiko (Annals of surgical oncology, 2014)
Keywords: Aged; Alcohol Drinking - genetics; Blood Vessels - pathology; Carcinoma, Squamous Cell - genetics; Carcinoma, Squamous Cell - secondary; Carcinoma, Squamous Cell - surgery; Cell Transformation, Neoplastic - genetics; Chromosomal Instability; Disease Progression; DNA Methylation; Esophageal Neoplasms - genetics; Esophageal Neoplasms - pathology; Esophageal Neoplasms - surgery; Esophagus; Exons; Female; Humans; Long Interspersed Nucleotide Elements - genetics; Loss of Heterozygosity; Lymphatic Metastasis; Lymphatic Vessels - pathology; Male; Medicine; Medicine & Public Health; Middle Aged; Mucous Membrane; Mutation Rate; Oncology; Smoking - genetics; Surgery; Surgical Oncology; Survival Rate; Translational Research and Biomarkers; Tumor Suppressor Protein p53 - genetics; Noncancerous Tissue; Single Nucleotide Polymorphism Array; Chromosomal Instability; Methylation Level; Esophageal Squamous Cell Carcinoma