Comorbid posttraumatic stress disorder complicates eating disorder treatment: A nationwide study

•Of patients with eating disorders, up to 16 % experience trauma and up to 4 % develop a posttraumatic stress disorder (PTSD).•Patients with the anorexia nervosa restricting subtype and unspecified feeding and eating disorders experience trauma less often than other eating disorders.•For patients wi...

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Published inPsychiatry research Vol. 351; p. 116563
Main Authors Hübel, Christopher, Johansson, Therese, Mundy, Jessica, Lin, Yuhao, Petersen, Liselotte V., Isomaa, Rasmus, Birgegård, Andreas
Format Journal Article
LanguageEnglish
Published Ireland Elsevier B.V 01.09.2025
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Online AccessGet full text
ISSN0165-1781
1872-7123
1872-7123
DOI10.1016/j.psychres.2025.116563

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Abstract •Of patients with eating disorders, up to 16 % experience trauma and up to 4 % develop a posttraumatic stress disorder (PTSD).•Patients with the anorexia nervosa restricting subtype and unspecified feeding and eating disorders experience trauma less often than other eating disorders.•For patients with eating disorders having comorbid PTSD represents a treatment complicating factor as it is associated with more frequent binge eating, nonsuicidal self-injury and suicidal symptoms at follow-up.•A dose-response relationship may exist between having comorbid PTSD and the frequency of the experienced suicidal symptoms. In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world’s largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.
AbstractList •Of patients with eating disorders, up to 16 % experience trauma and up to 4 % develop a posttraumatic stress disorder (PTSD).•Patients with the anorexia nervosa restricting subtype and unspecified feeding and eating disorders experience trauma less often than other eating disorders.•For patients with eating disorders having comorbid PTSD represents a treatment complicating factor as it is associated with more frequent binge eating, nonsuicidal self-injury and suicidal symptoms at follow-up.•A dose-response relationship may exist between having comorbid PTSD and the frequency of the experienced suicidal symptoms. In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world’s largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.
In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world's largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.
In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world's largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world's largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.
ArticleNumber 116563
Author Johansson, Therese
Birgegård, Andreas
Hübel, Christopher
Isomaa, Rasmus
Petersen, Liselotte V.
Mundy, Jessica
Lin, Yuhao
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  fullname: Johansson, Therese
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  givenname: Jessica
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  givenname: Yuhao
  surname: Lin
  fullname: Lin, Yuhao
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  givenname: Liselotte V.
  surname: Petersen
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  organization: National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
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  givenname: Rasmus
  orcidid: 0000-0002-2611-6007
  surname: Isomaa
  fullname: Isomaa, Rasmus
  organization: The Wellbeing Services County of Ostrobothnia, Finland
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  givenname: Andreas
  surname: Birgegård
  fullname: Birgegård, Andreas
  email: andreas.birgegard@ki.se
  organization: Centre for Eating Disorders Innovation, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
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Keywords Suicide attempts
Binge eating
Suicidality
Binge-eating disorder
Anorexia nervosa
Bulimia nervosa
Nonsuicidal self-injury
Self-induced vomiting
Language English
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Snippet •Of patients with eating disorders, up to 16 % experience trauma and up to 4 % develop a posttraumatic stress disorder (PTSD).•Patients with the anorexia...
In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting,...
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SubjectTerms Adolescent
Adult
Anorexia nervosa
Binge eating
Binge-eating disorder
Bulimia nervosa
Comorbidity
Cross-Sectional Studies
Feeding and Eating Disorders - epidemiology
Feeding and Eating Disorders - therapy
Female
Humans
Male
Middle Aged
Nonsuicidal self-injury
Self-induced vomiting
Self-Injurious Behavior - epidemiology
Stress Disorders, Post-Traumatic - epidemiology
Stress Disorders, Post-Traumatic - therapy
Suicidality
Suicide attempts
Sweden - epidemiology
Young Adult
Title Comorbid posttraumatic stress disorder complicates eating disorder treatment: A nationwide study
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https://dx.doi.org/10.1016/j.psychres.2025.116563
https://www.ncbi.nlm.nih.gov/pubmed/40472598
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Volume 351
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