Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons
•Genes in mouse 14qD2 locus are upregulated during maturation of hippocampal neurons.•They are relocated away from the nuclear periphery during neuronal maturation.•Decreased lamin B1 plays a role in relocation and transcription of the 14qD2 locus.•Overexpression of lamin B1 in neurons repressed tra...
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| Published in | Neuroscience research Vol. 173; pp. 22 - 33 |
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| Main Authors | , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Ireland
Elsevier B.V
01.12.2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0168-0102 1872-8111 1872-8111 |
| DOI | 10.1016/j.neures.2021.05.011 |
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| Abstract | •Genes in mouse 14qD2 locus are upregulated during maturation of hippocampal neurons.•They are relocated away from the nuclear periphery during neuronal maturation.•Decreased lamin B1 plays a role in relocation and transcription of the 14qD2 locus.•Overexpression of lamin B1 in neurons repressed transcription of the Egr3 gene.•Reduced lamin B1 may be crucial for chromatin organization in postmitotic neurons.
Gene expression programs and concomitant chromatin regulation change dramatically during the maturation of postmitotic neurons. Subnuclear positioning of gene loci is relevant to transcriptional regulation. However, little is known about subnuclear genome positioning in neuronal maturation. Using cultured murine hippocampal neurons, we found genomic locus 14qD2 to be enriched with genes that are upregulated during neuronal maturation. Reportedly, the locus is homologous to human 8p21.3, which has been extensively studied in neuropsychiatry and neurodegenerative diseases. Mapping of the 14qD2 locus in the nucleus revealed that it was relocated from the nuclear periphery to the interior. Moreover, we found a concomitant decrease in lamin B1 expression. Overexpression of lamin B1 in neurons using a lentiviral vector prevented the relocation of the 14qD2 locus and repressed the transcription of the Egr3 gene on this locus. Taken together, our results suggest that reduced lamin B1 expression during the maturation of neurons is important for appropriate subnuclear positioning of the genome and transcriptional programs. |
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| AbstractList | Gene expression programs and concomitant chromatin regulation change dramatically during the maturation of postmitotic neurons. Subnuclear positioning of gene loci is relevant to transcriptional regulation. However, little is known about subnuclear genome positioning in neuronal maturation. Using cultured murine hippocampal neurons, we found genomic locus 14qD2 to be enriched with genes that are upregulated during neuronal maturation. Reportedly, the locus is homologous to human 8p21.3, which has been extensively studied in neuropsychiatry and neurodegenerative diseases. Mapping of the 14qD2 locus in the nucleus revealed that it was relocated from the nuclear periphery to the interior. Moreover, we found a concomitant decrease in lamin B1 expression. Overexpression of lamin B1 in neurons using a lentiviral vector prevented the relocation of the 14qD2 locus and repressed the transcription of the Egr3 gene on this locus. Taken together, our results suggest that reduced lamin B1 expression during the maturation of neurons is important for appropriate subnuclear positioning of the genome and transcriptional programs.Gene expression programs and concomitant chromatin regulation change dramatically during the maturation of postmitotic neurons. Subnuclear positioning of gene loci is relevant to transcriptional regulation. However, little is known about subnuclear genome positioning in neuronal maturation. Using cultured murine hippocampal neurons, we found genomic locus 14qD2 to be enriched with genes that are upregulated during neuronal maturation. Reportedly, the locus is homologous to human 8p21.3, which has been extensively studied in neuropsychiatry and neurodegenerative diseases. Mapping of the 14qD2 locus in the nucleus revealed that it was relocated from the nuclear periphery to the interior. Moreover, we found a concomitant decrease in lamin B1 expression. Overexpression of lamin B1 in neurons using a lentiviral vector prevented the relocation of the 14qD2 locus and repressed the transcription of the Egr3 gene on this locus. Taken together, our results suggest that reduced lamin B1 expression during the maturation of neurons is important for appropriate subnuclear positioning of the genome and transcriptional programs. Gene expression programs and concomitant chromatin regulation change dramatically during the maturation of postmitotic neurons. Subnuclear positioning of gene loci is relevant to transcriptional regulation. However, little is known about subnuclear genome positioning in neuronal maturation. Using cultured murine hippocampal neurons, we found genomic locus 14qD2 to be enriched with genes that are upregulated during neuronal maturation. Reportedly, the locus is homologous to human 8p21.3, which has been extensively studied in neuropsychiatry and neurodegenerative diseases. Mapping of the 14qD2 locus in the nucleus revealed that it was relocated from the nuclear periphery to the interior. Moreover, we found a concomitant decrease in lamin B1 expression. Overexpression of lamin B1 in neurons using a lentiviral vector prevented the relocation of the 14qD2 locus and repressed the transcription of the Egr3 gene on this locus. Taken together, our results suggest that reduced lamin B1 expression during the maturation of neurons is important for appropriate subnuclear positioning of the genome and transcriptional programs. •Genes in mouse 14qD2 locus are upregulated during maturation of hippocampal neurons.•They are relocated away from the nuclear periphery during neuronal maturation.•Decreased lamin B1 plays a role in relocation and transcription of the 14qD2 locus.•Overexpression of lamin B1 in neurons repressed transcription of the Egr3 gene.•Reduced lamin B1 may be crucial for chromatin organization in postmitotic neurons. Gene expression programs and concomitant chromatin regulation change dramatically during the maturation of postmitotic neurons. Subnuclear positioning of gene loci is relevant to transcriptional regulation. However, little is known about subnuclear genome positioning in neuronal maturation. Using cultured murine hippocampal neurons, we found genomic locus 14qD2 to be enriched with genes that are upregulated during neuronal maturation. Reportedly, the locus is homologous to human 8p21.3, which has been extensively studied in neuropsychiatry and neurodegenerative diseases. Mapping of the 14qD2 locus in the nucleus revealed that it was relocated from the nuclear periphery to the interior. Moreover, we found a concomitant decrease in lamin B1 expression. Overexpression of lamin B1 in neurons using a lentiviral vector prevented the relocation of the 14qD2 locus and repressed the transcription of the Egr3 gene on this locus. Taken together, our results suggest that reduced lamin B1 expression during the maturation of neurons is important for appropriate subnuclear positioning of the genome and transcriptional programs. |
| Author | Uosaki, Hideki Yanagawa, Yuchio Noguchi, Azumi Ideta-Otsuka, Maky Arakawa, Hirokazu Ito, Kenji Nakashima, Hideyuki Kaneda, Ruri Kakizaki, Toshikazu Takizawa, Takumi Igarashi, Katsuhide Nakashima, Kinichi Uosaki, Yuichi |
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| Cites_doi | 10.1016/j.molcel.2010.03.016 10.1016/j.yjmcc.2015.02.021 10.1002/cne.10905 10.1016/j.stemcr.2017.05.001 10.1016/S0387-7604(01)00332-1 10.1523/JNEUROSCI.08-04-01454.1988 10.1073/pnas.191352298 10.1091/mbc.E15-05-0307 10.1186/gb-2011-12-5-222 10.1101/gr.190926.115 10.1016/j.cell.2017.04.022 10.1038/nprot.2006.356 10.1016/j.cell.2012.11.049 10.1093/hmg/ddu278 10.1091/mbc.e11-10-0884 10.1016/j.cell.2008.09.026 10.1242/jcs.02727 10.1016/j.tins.2011.09.001 10.1016/j.ceb.2010.04.002 10.1083/jcb.200101089 10.1186/gb-2004-5-10-r80 10.1111/j.1601-183X.2006.00224.x 10.1016/j.mcn.2007.02.004 10.1038/85109 10.1101/gad.223834.113 10.1016/j.semcdb.2013.12.012 10.1016/S1534-5807(01)00101-0 10.1091/mbc.e11-06-0504 10.1242/jcs.203430 10.1101/gad.179515.111 10.1523/JNEUROSCI.5994-10.2011 10.1083/jcb.135.6.1441 10.1073/pnas.0403954101 10.1016/j.neuron.2008.09.002 10.1038/nn.3995 10.1073/pnas.1303916110 10.1016/S0166-2236(98)01343-5 10.1016/j.celrep.2015.10.032 10.1146/annurev-genet-112414-055008 10.1038/bmt.2012.244 10.1523/JNEUROSCI.1085-12.2013 10.1093/biostatistics/kxp059 10.1016/j.cell.2013.01.009 10.1016/j.gpb.2016.04.004 10.1083/jcb.201206121 10.1016/j.ceb.2015.03.005 10.1101/gad.1652708 10.1074/jbc.M008363200 10.1146/annurev-biochem-060614-034115 10.1007/s00412-001-0179-8 10.1186/1471-2164-7-64 10.1242/dev.114454 10.1038/s41598-017-05078-6 10.1016/j.neuroscience.2008.06.039 10.1101/gad.217281.113 10.1007/s00418-015-1346-y 10.1038/ncomms15098 10.1016/j.ceb.2013.10.002 10.1038/nprot.2006.374 10.1038/nature15548 10.1093/cercor/10.10.981 10.1002/neu.10269 10.1371/journal.pone.0103525 10.1111/j.1471-4159.2011.07555.x 10.1016/j.cell.2013.02.048 10.1038/mp.2009.2 10.1093/nar/gkg778 10.1016/S0197-0186(96)00136-2 10.1016/j.ceb.2014.03.001 10.1006/excr.1999.4793 10.1128/MCB.25.23.10286-10300.2005 10.1038/nature06727 10.1101/gad.1634608 10.1093/hmg/dds005 10.1146/annurev-genom-091212-153515 10.1126/science.1068768 10.1073/pnas.0610765104 10.1242/dmm.001065 |
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| References | Padeken, Heun (bib0255) 2014; 28 Takizawa, Gudla, Guo, Lockett, Misteli (bib0315) 2008; 22 van Steensel, Belmont (bib0360) 2017; 169 Gruenbaum, Foisner (bib0115) 2015; 84 Beckmann, Wilce (bib0020) 1997; 31 Lin, Ptacek, Fu (bib0205) 2011; 31 West, Chen, Dalva, Dolmetsch, Kornhauser, Shaywitz, Takasu, Tao, Greenberg (bib0375) 2001; 98 Dechat, Pfleghaar, Sengupta, Shimi, Shumaker, Solimando, Goldman (bib0050) 2008; 22 Harewood, Fraser (bib0125) 2014; 23 McCall, Bolstad, Irizarry (bib0230) 2010; 11 Daigle, Beaudouin, Hartnell, Imreh, Hallberg, Lippincott-Schwartz, Ellenberg (bib0045) 2001; 154 Belmont (bib0025) 2014; 26 Tamamaki, Yanagawa, Tomioka, Miyazaki, Obata, Kaneko (bib0335) 2003; 467 Chang, Li, Shao, Li, Ai, Xue, Hou, Zhang, Li, Fan, He, Li, Sun (bib0035) 2020 Takizawa, Ochiai, Nakashima, Taga (bib0330) 2003; 31 Frank, Liu, Wijayatunge, Song, Biegler, Yang, Vockley, Safi, Gersbach, Crawford, West (bib0080) 2015; 18 Kaech, Banker (bib0140) 2006; 1 Solovei, Wang, Thanisch, Schmidt, Krebs, Zwerger, Cohen, Devys, Foisner, Peichl, Herrmann, Blum, Engelkamp, Stewart, Leonhardt, Joffe (bib0300) 2013; 152 Dierssen, Ramakers (bib0055) 2006; 5 Freund, Laberge, Demaria, Campisi (bib0085) 2012; 23 Takizawa, Meaburn, Misteli (bib0320) 2008; 135 Martou, De Boni (bib0215) 2000; 256 Walczak, Szczepankiewicz, Ruszczycki, Magalska, Zamlynska, Dzwonek, Wilczek, Zybura-Broda, Rylski, Malinowska, Dabrowski, Szczepinska, Pawlowski, Pyskaty, Wlodarczyk, Szczerbal, Switonski, Cremer, Wilczynski (bib0370) 2013; 33 Matsuhashi, Hishiki, Zhou, Ono, Kaneda, Iso, Yamaguchi, Endo, Katsumata, Atsushi, Yamamoto, Shirakawa, Yan, Shinmura, Suematsu, Fukuda, Sano (bib0225) 2015; 82 Tabares-Seisdedos, Rubenstein (bib0305) 2009; 14 Li, Carter, Gao, Whitehead, Tourtellotte (bib0190) 2005; 25 Kosak, Skok, Medina, Riblet, Le Beau, Fisher, Singh (bib0180) 2002; 296 Williams, Azuara, Perry, Sauer, Dvorkina, Jorgensen, Roix, McQueen, Misteli, Merkenschlager, Fisher (bib0380) 2006; 119 Shah, Donahue, Otte, Capell, Nelson, Cao, Aggarwala, Cruickshanks, Rai, McBryan, Gregory, Adams, Berger (bib0285) 2013; 27 Hutchison (bib0130) 2014; 29 Slee, Adrain, Martin (bib0295) 2001; 276 Hardingham, Arnold, Bading (bib0120) 2001; 4 Misteli (bib0235) 2013; 152 O’Donovan, Tourtellotte, Millbrandt, Baraban (bib0250) 1999; 22 Ventura, Meissner, Dillon, McManus, Sharp, Van Parijs, Jaenisch, Jacks (bib0365) 2004; 101 Dittmer, Misteli (bib0060) 2011; 12 Bickmore (bib0030) 2013; 14 Kaufmann, Moser (bib0155) 2000; 10 Lin, Fu (bib0200) 2009; 2 Wright, Shay (bib0385) 2006; 1 Kaur, Karolina, Sepramaniam, Armugam, Jeyaseelan (bib0160) 2014; 9 Peric-Hupkes, Meuleman, Pagie, Bruggeman, Solovei, Brugman, Graf, Flicek, Kerkhoven, van Lohuizen, Reinders, Wessels, van Steensel (bib0260) 2010; 38 Coffinier, Jung, Nobumori, Chang, Tu, Barnes, Yoshinaga, de Jong, Vergnes, Reue, Fong, Young (bib0040) 2011; 22 Yasui, Uezono, Nakashima, Noguchi, Matsuda, Noda-Andoh, Okano, Nakashima (bib0395) 2017; 8 Barton, Soshnev, Geyer (bib0015) 2015; 34 Martou, Park, De Boni (bib0220) 2002; 110 Uribe, Wong, Graham, Cusack, Skotte, Pouladi, Xie, Feinberg, Ou, Ouyang, Deng, Franciosi, Bissada, Spreeuw, Zhang, Ehrnhoefer, Vaid, Miller, Deshmukh, Howland, Hayden (bib0355) 2012; 21 Kanno, Aisaki, Igarashi, Nakatsu, Ono, Kodama, Nagao (bib0150) 2006; 7 Dotti, Sullivan, Banker (bib0065) 1988; 8 Armstrong (bib0010) 2001; 23 Arimura, Menager, Fukata, Kaibuchi (bib0005) 2004; 58 Dou, Xu, Donahue, Shimi, Pan, Zhu, Ivanov, Capell, Drake, Shah, Catanzaro, Ricketts, Lamark, Adam, Marmorstein, Zong, Johansen, Goldman, Adams, Berger (bib0070) 2015; 527 Graham, Ehrnhoefer, Hayden (bib0105) 2011; 34 Shimi, Butin-Israeli, Adam, Hamanaka, Goldman, Lucas, Shumaker, Kosak, Chandel, Goldman (bib0290) 2011; 25 Gentleman, Carey, Bates, Bolstad, Dettling, Dudoit, Ellis, Gautier, Ge, Gentry, Hornik, Hothorn, Huber, Iacus, Irizarry, Leisch, Li, Maechler, Rossini, Sawitzki, Smith, Smyth, Tierney, Yang, Zhang (bib0090) 2004; 5 Li, Yun, Keblesh, Trommer, Xiong, Radulovic, Tourtellotte (bib0195) 2007; 35 Giacomini, Mahajani, Ruffilli, Marotta, Gasparini (bib0095) 2016; 27 Reddy, Zullo, Bertolino, Singh (bib0270) 2008; 452 Takano, Xu, Funahashi, Namba, Kaibuchi (bib0310) 2015; 142 Sanosaka, Namihira, Asano, Kohyama, Aisaki, Igarashi, Kanno, Nakashima (bib0280) 2008; 155 Yamada, Gerber, Iwayama, Ohnishi, Ohba, Toyota, Aruga, Minabe, Tonegawa, Yoshikawa (bib0390) 2007; 104 Rao, Perez, White (bib0265) 1996; 135 Naetar, Ferraioli, Foisner (bib0240) 2017; 130 Kohwi, Lupton, Lai, Miller, Doe (bib0175) 2013; 152 Mahajani, Giacomini, Marinaro, De Pietri Tonelli, Contestabile, Gasparini (bib0210) 2017; 7 Kim, Roberts, Hu, Lau, Brooks-Kayal, Farb, Russek (bib0165) 2012; 120 Uosaki, Taguchi (bib0350) 2016; 14 Jung, Nobumori, Goulbourne, Tu, Lee, Tatar, Wu, Yoshinaga, de Jong, Coffinier, Fong, Young (bib0135) 2013; 110 Kind, van Steensel (bib0170) 2010; 22 Nguyen, Bosco (bib0245) 2015; 49 Thakurela, Sahu, Garding, Tiwari (bib0340) 2015; 25 Kanda (bib0145) 2013; 48 Dreesen, Chojnowski, Ong, Zhao, Common, Lunny, Lane, Lee, Vardy, Stewart, Colman (bib0075) 2013; 200 Greer, Greenberg (bib0110) 2008; 59 Sadaie, Salama, Carroll, Tomimatsu, Chandra, Young, Narita, Perez-Mancera, Bennett, Chong, Kimura, Narita (bib0275) 2013; 27 Lemaitre, Bickmore (bib0185) 2015; 144 Uosaki, Cahan, Lee, Wang, Miyamoto, Fernandez, Kass, Kwon (bib0345) 2015; 13 Gigante, Dibattista, Dong, Zheng, Yue, Young, Reisert, Zheng, Zhao (bib0100) 2017; 8 Takizawa, Nakashima, Namihira, Ochiai, Uemura, Yanagisawa, Fujita, Nakao, Taga (bib0325) 2001; 1 Barton (10.1016/j.neures.2021.05.011_bib0015) 2015; 34 Thakurela (10.1016/j.neures.2021.05.011_bib0340) 2015; 25 Dou (10.1016/j.neures.2021.05.011_bib0070) 2015; 527 Nguyen (10.1016/j.neures.2021.05.011_bib0245) 2015; 49 Sadaie (10.1016/j.neures.2021.05.011_bib0275) 2013; 27 Kanda (10.1016/j.neures.2021.05.011_bib0145) 2013; 48 Sanosaka (10.1016/j.neures.2021.05.011_bib0280) 2008; 155 Armstrong (10.1016/j.neures.2021.05.011_bib0010) 2001; 23 Gruenbaum (10.1016/j.neures.2021.05.011_bib0115) 2015; 84 Frank (10.1016/j.neures.2021.05.011_bib0080) 2015; 18 Dittmer (10.1016/j.neures.2021.05.011_bib0060) 2011; 12 Slee (10.1016/j.neures.2021.05.011_bib0295) 2001; 276 Uribe (10.1016/j.neures.2021.05.011_bib0355) 2012; 21 Gigante (10.1016/j.neures.2021.05.011_bib0100) 2017; 8 Lin (10.1016/j.neures.2021.05.011_bib0205) 2011; 31 Kaur (10.1016/j.neures.2021.05.011_bib0160) 2014; 9 Uosaki (10.1016/j.neures.2021.05.011_bib0350) 2016; 14 Jung (10.1016/j.neures.2021.05.011_bib0135) 2013; 110 Hutchison (10.1016/j.neures.2021.05.011_bib0130) 2014; 29 van Steensel (10.1016/j.neures.2021.05.011_bib0360) 2017; 169 Gentleman (10.1016/j.neures.2021.05.011_bib0090) 2004; 5 Padeken (10.1016/j.neures.2021.05.011_bib0255) 2014; 28 Naetar (10.1016/j.neures.2021.05.011_bib0240) 2017; 130 Chang (10.1016/j.neures.2021.05.011_bib0035) 2020 Takizawa (10.1016/j.neures.2021.05.011_bib0315) 2008; 22 Lin (10.1016/j.neures.2021.05.011_bib0200) 2009; 2 Shimi (10.1016/j.neures.2021.05.011_bib0290) 2011; 25 Takano (10.1016/j.neures.2021.05.011_bib0310) 2015; 142 Peric-Hupkes (10.1016/j.neures.2021.05.011_bib0260) 2010; 38 Li (10.1016/j.neures.2021.05.011_bib0190) 2005; 25 Dotti (10.1016/j.neures.2021.05.011_bib0065) 1988; 8 Reddy (10.1016/j.neures.2021.05.011_bib0270) 2008; 452 Hardingham (10.1016/j.neures.2021.05.011_bib0120) 2001; 4 Wright (10.1016/j.neures.2021.05.011_bib0385) 2006; 1 Takizawa (10.1016/j.neures.2021.05.011_bib0325) 2001; 1 Belmont (10.1016/j.neures.2021.05.011_bib0025) 2014; 26 Dierssen (10.1016/j.neures.2021.05.011_bib0055) 2006; 5 Kaech (10.1016/j.neures.2021.05.011_bib0140) 2006; 1 Freund (10.1016/j.neures.2021.05.011_bib0085) 2012; 23 Matsuhashi (10.1016/j.neures.2021.05.011_bib0225) 2015; 82 McCall (10.1016/j.neures.2021.05.011_bib0230) 2010; 11 Uosaki (10.1016/j.neures.2021.05.011_bib0345) 2015; 13 Beckmann (10.1016/j.neures.2021.05.011_bib0020) 1997; 31 Solovei (10.1016/j.neures.2021.05.011_bib0300) 2013; 152 Walczak (10.1016/j.neures.2021.05.011_bib0370) 2013; 33 Yamada (10.1016/j.neures.2021.05.011_bib0390) 2007; 104 O’Donovan (10.1016/j.neures.2021.05.011_bib0250) 1999; 22 Tamamaki (10.1016/j.neures.2021.05.011_bib0335) 2003; 467 Kohwi (10.1016/j.neures.2021.05.011_bib0175) 2013; 152 Li (10.1016/j.neures.2021.05.011_bib0195) 2007; 35 Misteli (10.1016/j.neures.2021.05.011_bib0235) 2013; 152 West (10.1016/j.neures.2021.05.011_bib0375) 2001; 98 Harewood (10.1016/j.neures.2021.05.011_bib0125) 2014; 23 Kaufmann (10.1016/j.neures.2021.05.011_bib0155) 2000; 10 Kosak (10.1016/j.neures.2021.05.011_bib0180) 2002; 296 Kim (10.1016/j.neures.2021.05.011_bib0165) 2012; 120 Lemaitre (10.1016/j.neures.2021.05.011_bib0185) 2015; 144 Yasui (10.1016/j.neures.2021.05.011_bib0395) 2017; 8 Rao (10.1016/j.neures.2021.05.011_bib0265) 1996; 135 Graham (10.1016/j.neures.2021.05.011_bib0105) 2011; 34 Martou (10.1016/j.neures.2021.05.011_bib0215) 2000; 256 Shah (10.1016/j.neures.2021.05.011_bib0285) 2013; 27 Dreesen (10.1016/j.neures.2021.05.011_bib0075) 2013; 200 Arimura (10.1016/j.neures.2021.05.011_bib0005) 2004; 58 Coffinier (10.1016/j.neures.2021.05.011_bib0040) 2011; 22 Williams (10.1016/j.neures.2021.05.011_bib0380) 2006; 119 Dechat (10.1016/j.neures.2021.05.011_bib0050) 2008; 22 Kanno (10.1016/j.neures.2021.05.011_bib0150) 2006; 7 Bickmore (10.1016/j.neures.2021.05.011_bib0030) 2013; 14 Mahajani (10.1016/j.neures.2021.05.011_bib0210) 2017; 7 Martou (10.1016/j.neures.2021.05.011_bib0220) 2002; 110 Ventura (10.1016/j.neures.2021.05.011_bib0365) 2004; 101 Daigle (10.1016/j.neures.2021.05.011_bib0045) 2001; 154 Giacomini (10.1016/j.neures.2021.05.011_bib0095) 2016; 27 Greer (10.1016/j.neures.2021.05.011_bib0110) 2008; 59 Tabares-Seisdedos (10.1016/j.neures.2021.05.011_bib0305) 2009; 14 Takizawa (10.1016/j.neures.2021.05.011_bib0330) 2003; 31 Takizawa (10.1016/j.neures.2021.05.011_bib0320) 2008; 135 Kind (10.1016/j.neures.2021.05.011_bib0170) 2010; 22 |
| References_xml | – volume: 22 start-page: 167 year: 1999 end-page: 173 ident: bib0250 article-title: The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience publication-title: Trends Neurosci – volume: 26 start-page: 69 year: 2014 end-page: 78 ident: bib0025 article-title: Large-scale chromatin organization: the good, the surprising, and the still perplexing publication-title: Curr Opin Cell Biol – volume: 59 start-page: 846 year: 2008 end-page: 860 ident: bib0110 article-title: From synapse to nucleus: Calcium-dependent gene transcription in the control of synapse development and function publication-title: Neuron – volume: 14 start-page: 67 year: 2013 end-page: 84 ident: bib0030 article-title: The spatial organization of the human genome publication-title: Annu Rev Genomics Hum Genet – volume: 27 start-page: 1800 year: 2013 end-page: 1808 ident: bib0275 article-title: Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence publication-title: Genes Dev – volume: 9 year: 2014 ident: bib0160 article-title: Expression profiling of RNA transcripts during neuronal maturation and ischemic injury publication-title: PLoS One – volume: 58 start-page: 34 year: 2004 end-page: 47 ident: bib0005 article-title: Role of CRMP-2 in neuronal polarity publication-title: J Neurobiol – volume: 152 start-page: 1209 year: 2013 end-page: 1212 ident: bib0235 article-title: The cell biology of genomes: bringing the double helix to life publication-title: Cell – volume: 104 start-page: 2815 year: 2007 end-page: 2820 ident: bib0390 article-title: Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia publication-title: Proc Natl Acad Sci U S A – volume: 22 start-page: 320 year: 2010 end-page: 325 ident: bib0170 article-title: Genome-nuclear lamina interactions and gene regulation publication-title: Curr Opin Cell Biol – volume: 527 start-page: 105 year: 2015 end-page: 109 ident: bib0070 article-title: Autophagy mediates degradation of nuclear lamina publication-title: Nature – volume: 11 start-page: 242 year: 2010 end-page: 253 ident: bib0230 article-title: Frozen robust multiarray analysis (fRMA) publication-title: Biostatistics – volume: 35 start-page: 76 year: 2007 end-page: 88 ident: bib0195 article-title: Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory publication-title: Mol Cell Neurosci – volume: 276 start-page: 7320 year: 2001 end-page: 7326 ident: bib0295 article-title: Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis publication-title: J Biol Chem – volume: 48 start-page: 452 year: 2013 end-page: 458 ident: bib0145 article-title: Investigation of the freely available easy-to-use software’ EZR’ for medical statistics publication-title: Bone Marrow Transplant – volume: 452 start-page: 243 year: 2008 end-page: 247 ident: bib0270 article-title: Transcriptional repression mediated by repositioning of genes to the nuclear lamina publication-title: Nature – volume: 22 start-page: 4683 year: 2011 end-page: 4693 ident: bib0040 article-title: Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons publication-title: Mol Biol Cell – volume: 14 start-page: 563 year: 2009 end-page: 589 ident: bib0305 article-title: Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer publication-title: Mol Psychiatry – volume: 33 start-page: 2507 year: 2013 end-page: 2511 ident: bib0370 article-title: Novel higher-order epigenetic regulation of the Bdnf gene upon seizures publication-title: J Neurosci – volume: 142 start-page: 2088 year: 2015 end-page: 2093 ident: bib0310 article-title: Neuronal polarization publication-title: Development – volume: 25 start-page: 1309 year: 2015 end-page: 1324 ident: bib0340 article-title: Dynamics and function of distal regulatory elements during neurogenesis and neuroplasticity publication-title: Genome Res – volume: 34 start-page: 646 year: 2011 end-page: 656 ident: bib0105 article-title: Caspase-6 and neurodegeneration publication-title: Trends Neurosci – year: 2020 ident: bib0035 article-title: Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells publication-title: Protein Cell. – volume: 10 start-page: 981 year: 2000 end-page: 991 ident: bib0155 article-title: Dendritic anomalies in disorders associated with mental retardation publication-title: Cereb Cortex – volume: 101 start-page: 10380 year: 2004 end-page: 10385 ident: bib0365 article-title: Cre-lox-regulated conditional RNA interference from transgenes publication-title: Proc Natl Acad Sci U S A – volume: 5 start-page: 48 year: 2006 end-page: 60 ident: bib0055 article-title: Dendritic pathology in mental retardation: from molecular genetics to neurobiology publication-title: Genes Brain Behav – volume: 27 start-page: 1787 year: 2013 end-page: 1799 ident: bib0285 article-title: Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape publication-title: Genes Dev – volume: 130 start-page: 2087 year: 2017 end-page: 2096 ident: bib0240 article-title: Lamins in the nuclear interior - life outside the lamina publication-title: J Cell Sci – volume: 119 start-page: 132 year: 2006 end-page: 140 ident: bib0380 article-title: Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus publication-title: J Cell Sci – volume: 21 start-page: 1954 year: 2012 end-page: 1967 ident: bib0355 article-title: Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice publication-title: Hum Mol Genet – volume: 31 start-page: 477 year: 1997 end-page: 510 ident: bib0020 article-title: Egr transcription factors in the nervous system publication-title: Neurochem Int – volume: 154 start-page: 71 year: 2001 end-page: 84 ident: bib0045 article-title: Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells publication-title: J Cell Biol – volume: 12 start-page: 222 year: 2011 ident: bib0060 article-title: The lamin protein family publication-title: Genome Biol – volume: 82 start-page: 116 year: 2015 end-page: 124 ident: bib0225 article-title: Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart publication-title: J Mol Cell Cardiol – volume: 135 start-page: 9 year: 2008 end-page: 13 ident: bib0320 article-title: The meaning of gene positioning publication-title: Cell – volume: 200 start-page: 605 year: 2013 end-page: 617 ident: bib0075 article-title: Lamin B1 fluctuations have differential effects on cellular proliferation and senescence publication-title: J Cell Biol – volume: 38 start-page: 603 year: 2010 end-page: 613 ident: bib0260 article-title: Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation publication-title: Mol Cell – volume: 8 start-page: 15098 year: 2017 ident: bib0100 article-title: Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation publication-title: Nat Commun – volume: 8 start-page: 1454 year: 1988 end-page: 1468 ident: bib0065 article-title: The establishment of polarity by hippocampal neurons in culture publication-title: J Neurosci – volume: 155 start-page: 780 year: 2008 end-page: 788 ident: bib0280 article-title: Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cells publication-title: Neuroscience – volume: 169 start-page: 780 year: 2017 end-page: 791 ident: bib0360 article-title: Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression publication-title: Cell – volume: 25 start-page: 10286 year: 2005 end-page: 10300 ident: bib0190 article-title: The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors publication-title: Mol Cell Biol – volume: 120 start-page: 210 year: 2012 end-page: 219 ident: bib0165 article-title: Brain-derived neurotrophic factor uses CREB and Egr3 to regulate NMDA receptor levels in cortical neurons publication-title: J Neurochem – volume: 1 start-page: 749 year: 2001 end-page: 758 ident: bib0325 article-title: DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain publication-title: Dev Cell – volume: 98 start-page: 11024 year: 2001 end-page: 11031 ident: bib0375 article-title: Calcium regulation of neuronal gene expression publication-title: Proc Natl Acad Sci U S A – volume: 110 start-page: E1923 year: 2013 end-page: 1932 ident: bib0135 article-title: Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration publication-title: Proc Natl Acad Sci U S A – volume: 22 start-page: 489 year: 2008 end-page: 498 ident: bib0315 article-title: Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP publication-title: Genes Dev – volume: 1 start-page: 2406 year: 2006 end-page: 2415 ident: bib0140 article-title: Culturing hippocampal neurons publication-title: Nat Protoc – volume: 1 start-page: 2088 year: 2006 end-page: 2090 ident: bib0385 article-title: Inexpensive low-oxygen incubators publication-title: Nat Protoc – volume: 5 start-page: R80 year: 2004 ident: bib0090 article-title: Bioconductor: open software development for computational biology and bioinformatics publication-title: Genome Biol – volume: 29 start-page: 158 year: 2014 end-page: 163 ident: bib0130 article-title: B-type lamins in health and disease publication-title: Semin Cell Dev Biol – volume: 256 start-page: 131 year: 2000 end-page: 139 ident: bib0215 article-title: Nuclear topology of murine, cerebellar Purkinje neurons: changes as a function of development publication-title: Exp Cell Res – volume: 7 start-page: 4897 year: 2017 ident: bib0210 article-title: Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis publication-title: Sci Rep – volume: 28 start-page: 54 year: 2014 end-page: 60 ident: bib0255 article-title: Nucleolus and nuclear periphery: velcro for heterochromatin publication-title: Curr Opin Cell Biol – volume: 34 start-page: 1 year: 2015 end-page: 8 ident: bib0015 article-title: Networking in the nucleus: a spotlight on LEM-domain proteins publication-title: Curr Opin Cell Biol – volume: 49 start-page: 627 year: 2015 end-page: 646 ident: bib0245 article-title: Gene Positioning Effects on Expression in Eukaryotes publication-title: Annu Rev Genet – volume: 152 start-page: 584 year: 2013 end-page: 598 ident: bib0300 article-title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation publication-title: Cell – volume: 8 start-page: 1743 year: 2017 end-page: 1756 ident: bib0395 article-title: Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells publication-title: Stem Cell Reports – volume: 22 start-page: 832 year: 2008 end-page: 853 ident: bib0050 article-title: Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin publication-title: Genes Dev – volume: 152 start-page: 97 year: 2013 end-page: 108 ident: bib0175 article-title: Developmentally regulated subnuclear genome reorganization restricts neural progenitor competence in Drosophila publication-title: Cell – volume: 14 start-page: 207 year: 2016 end-page: 215 ident: bib0350 article-title: Comparative Gene Expression Analysis of Mouse and Human Cardiac Maturation publication-title: Genomics Proteomics Bioinformatics – volume: 18 start-page: 647 year: 2015 end-page: 656 ident: bib0080 article-title: Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum publication-title: Nat Neurosci – volume: 4 start-page: 261 year: 2001 end-page: 267 ident: bib0120 article-title: Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity publication-title: Nat Neurosci – volume: 144 start-page: 111 year: 2015 end-page: 122 ident: bib0185 article-title: Chromatin at the nuclear periphery and the regulation of genome functions publication-title: Histochem Cell Biol – volume: 2 start-page: 178 year: 2009 end-page: 188 ident: bib0200 article-title: miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination publication-title: Dis Model Mech – volume: 25 start-page: 2579 year: 2011 end-page: 2593 ident: bib0290 article-title: The role of nuclear lamin B1 in cell proliferation and senescence publication-title: Genes Dev – volume: 13 start-page: 1705 year: 2015 end-page: 1716 ident: bib0345 article-title: Transcriptional Landscape of Cardiomyocyte Maturation publication-title: Cell Rep – volume: 31 start-page: 1163 year: 2011 end-page: 1166 ident: bib0205 article-title: Adult-onset autosomal dominant leukodystrophy: linking nuclear envelope to myelin publication-title: J Neurosci – volume: 296 start-page: 158 year: 2002 end-page: 162 ident: bib0180 article-title: Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development publication-title: Science – volume: 84 start-page: 131 year: 2015 end-page: 164 ident: bib0115 article-title: Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation publication-title: Annu Rev Biochem – volume: 23 start-page: S72 year: 2001 end-page: 76 ident: bib0010 article-title: Rett syndrome neuropathology review 2000 publication-title: Brain Dev – volume: 7 start-page: 64 year: 2006 ident: bib0150 article-title: Per cell" normalization method for mRNA measurement by quantitative PCR and microarrays publication-title: BMC Genomics – volume: 135 start-page: 1441 year: 1996 end-page: 1455 ident: bib0265 article-title: Lamin proteolysis facilitates nuclear events during apoptosis publication-title: J Cell Biol – volume: 23 start-page: 2066 year: 2012 end-page: 2075 ident: bib0085 article-title: Lamin B1 loss is a senescence-associated biomarker publication-title: Mol Biol Cell – volume: 110 start-page: 542 year: 2002 end-page: 549 ident: bib0220 article-title: Intranuclear relocation of the Plc beta3 sequence in cerebellar purkinje neurons: temporal association with de novo expression during development publication-title: Chromosoma – volume: 27 start-page: 35 year: 2016 end-page: 47 ident: bib0095 article-title: Lamin B1 protein is required for dendrite development in primary mouse cortical neurons publication-title: Mol Biol Cell – volume: 31 start-page: 5723 year: 2003 end-page: 5731 ident: bib0330 article-title: Enhanced gene activation by Notch and BMP signaling cross-talk publication-title: Nucleic Acids Res – volume: 23 start-page: R76 year: 2014 end-page: 82 ident: bib0125 article-title: The impact of chromosomal rearrangements on regulation of gene expression publication-title: Hum Mol Genet – volume: 467 start-page: 60 year: 2003 end-page: 79 ident: bib0335 article-title: Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse publication-title: J Comp Neurol – volume: 38 start-page: 603 year: 2010 ident: 10.1016/j.neures.2021.05.011_bib0260 article-title: Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation publication-title: Mol Cell doi: 10.1016/j.molcel.2010.03.016 – volume: 82 start-page: 116 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0225 article-title: Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2015.02.021 – volume: 467 start-page: 60 year: 2003 ident: 10.1016/j.neures.2021.05.011_bib0335 article-title: Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse publication-title: J Comp Neurol doi: 10.1002/cne.10905 – volume: 8 start-page: 1743 year: 2017 ident: 10.1016/j.neures.2021.05.011_bib0395 article-title: Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells publication-title: Stem Cell Reports doi: 10.1016/j.stemcr.2017.05.001 – volume: 23 start-page: S72 issue: Suppl 1 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0010 article-title: Rett syndrome neuropathology review 2000 publication-title: Brain Dev doi: 10.1016/S0387-7604(01)00332-1 – volume: 8 start-page: 1454 year: 1988 ident: 10.1016/j.neures.2021.05.011_bib0065 article-title: The establishment of polarity by hippocampal neurons in culture publication-title: J Neurosci doi: 10.1523/JNEUROSCI.08-04-01454.1988 – volume: 98 start-page: 11024 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0375 article-title: Calcium regulation of neuronal gene expression publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.191352298 – volume: 27 start-page: 35 year: 2016 ident: 10.1016/j.neures.2021.05.011_bib0095 article-title: Lamin B1 protein is required for dendrite development in primary mouse cortical neurons publication-title: Mol Biol Cell doi: 10.1091/mbc.E15-05-0307 – year: 2020 ident: 10.1016/j.neures.2021.05.011_bib0035 article-title: Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells publication-title: Protein Cell. – volume: 12 start-page: 222 year: 2011 ident: 10.1016/j.neures.2021.05.011_bib0060 article-title: The lamin protein family publication-title: Genome Biol doi: 10.1186/gb-2011-12-5-222 – volume: 25 start-page: 1309 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0340 article-title: Dynamics and function of distal regulatory elements during neurogenesis and neuroplasticity publication-title: Genome Res doi: 10.1101/gr.190926.115 – volume: 169 start-page: 780 year: 2017 ident: 10.1016/j.neures.2021.05.011_bib0360 article-title: Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression publication-title: Cell doi: 10.1016/j.cell.2017.04.022 – volume: 1 start-page: 2406 year: 2006 ident: 10.1016/j.neures.2021.05.011_bib0140 article-title: Culturing hippocampal neurons publication-title: Nat Protoc doi: 10.1038/nprot.2006.356 – volume: 152 start-page: 97 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0175 article-title: Developmentally regulated subnuclear genome reorganization restricts neural progenitor competence in Drosophila publication-title: Cell doi: 10.1016/j.cell.2012.11.049 – volume: 23 start-page: R76 year: 2014 ident: 10.1016/j.neures.2021.05.011_bib0125 article-title: The impact of chromosomal rearrangements on regulation of gene expression publication-title: Hum Mol Genet doi: 10.1093/hmg/ddu278 – volume: 23 start-page: 2066 year: 2012 ident: 10.1016/j.neures.2021.05.011_bib0085 article-title: Lamin B1 loss is a senescence-associated biomarker publication-title: Mol Biol Cell doi: 10.1091/mbc.e11-10-0884 – volume: 135 start-page: 9 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0320 article-title: The meaning of gene positioning publication-title: Cell doi: 10.1016/j.cell.2008.09.026 – volume: 119 start-page: 132 year: 2006 ident: 10.1016/j.neures.2021.05.011_bib0380 article-title: Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus publication-title: J Cell Sci doi: 10.1242/jcs.02727 – volume: 34 start-page: 646 year: 2011 ident: 10.1016/j.neures.2021.05.011_bib0105 article-title: Caspase-6 and neurodegeneration publication-title: Trends Neurosci doi: 10.1016/j.tins.2011.09.001 – volume: 22 start-page: 320 year: 2010 ident: 10.1016/j.neures.2021.05.011_bib0170 article-title: Genome-nuclear lamina interactions and gene regulation publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2010.04.002 – volume: 154 start-page: 71 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0045 article-title: Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells publication-title: J Cell Biol doi: 10.1083/jcb.200101089 – volume: 5 start-page: R80 year: 2004 ident: 10.1016/j.neures.2021.05.011_bib0090 article-title: Bioconductor: open software development for computational biology and bioinformatics publication-title: Genome Biol doi: 10.1186/gb-2004-5-10-r80 – volume: 5 start-page: 48 issue: Suppl 2 year: 2006 ident: 10.1016/j.neures.2021.05.011_bib0055 article-title: Dendritic pathology in mental retardation: from molecular genetics to neurobiology publication-title: Genes Brain Behav doi: 10.1111/j.1601-183X.2006.00224.x – volume: 35 start-page: 76 year: 2007 ident: 10.1016/j.neures.2021.05.011_bib0195 article-title: Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory publication-title: Mol Cell Neurosci doi: 10.1016/j.mcn.2007.02.004 – volume: 4 start-page: 261 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0120 article-title: Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity publication-title: Nat Neurosci doi: 10.1038/85109 – volume: 27 start-page: 1787 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0285 article-title: Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape publication-title: Genes Dev doi: 10.1101/gad.223834.113 – volume: 29 start-page: 158 year: 2014 ident: 10.1016/j.neures.2021.05.011_bib0130 article-title: B-type lamins in health and disease publication-title: Semin Cell Dev Biol doi: 10.1016/j.semcdb.2013.12.012 – volume: 1 start-page: 749 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0325 article-title: DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain publication-title: Dev Cell doi: 10.1016/S1534-5807(01)00101-0 – volume: 22 start-page: 4683 year: 2011 ident: 10.1016/j.neures.2021.05.011_bib0040 article-title: Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons publication-title: Mol Biol Cell doi: 10.1091/mbc.e11-06-0504 – volume: 130 start-page: 2087 year: 2017 ident: 10.1016/j.neures.2021.05.011_bib0240 article-title: Lamins in the nuclear interior - life outside the lamina publication-title: J Cell Sci doi: 10.1242/jcs.203430 – volume: 25 start-page: 2579 year: 2011 ident: 10.1016/j.neures.2021.05.011_bib0290 article-title: The role of nuclear lamin B1 in cell proliferation and senescence publication-title: Genes Dev doi: 10.1101/gad.179515.111 – volume: 31 start-page: 1163 year: 2011 ident: 10.1016/j.neures.2021.05.011_bib0205 article-title: Adult-onset autosomal dominant leukodystrophy: linking nuclear envelope to myelin publication-title: J Neurosci doi: 10.1523/JNEUROSCI.5994-10.2011 – volume: 135 start-page: 1441 year: 1996 ident: 10.1016/j.neures.2021.05.011_bib0265 article-title: Lamin proteolysis facilitates nuclear events during apoptosis publication-title: J Cell Biol doi: 10.1083/jcb.135.6.1441 – volume: 101 start-page: 10380 year: 2004 ident: 10.1016/j.neures.2021.05.011_bib0365 article-title: Cre-lox-regulated conditional RNA interference from transgenes publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0403954101 – volume: 59 start-page: 846 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0110 article-title: From synapse to nucleus: Calcium-dependent gene transcription in the control of synapse development and function publication-title: Neuron doi: 10.1016/j.neuron.2008.09.002 – volume: 18 start-page: 647 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0080 article-title: Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum publication-title: Nat Neurosci doi: 10.1038/nn.3995 – volume: 110 start-page: E1923 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0135 article-title: Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1303916110 – volume: 22 start-page: 167 year: 1999 ident: 10.1016/j.neures.2021.05.011_bib0250 article-title: The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience publication-title: Trends Neurosci doi: 10.1016/S0166-2236(98)01343-5 – volume: 13 start-page: 1705 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0345 article-title: Transcriptional Landscape of Cardiomyocyte Maturation publication-title: Cell Rep doi: 10.1016/j.celrep.2015.10.032 – volume: 49 start-page: 627 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0245 article-title: Gene Positioning Effects on Expression in Eukaryotes publication-title: Annu Rev Genet doi: 10.1146/annurev-genet-112414-055008 – volume: 48 start-page: 452 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0145 article-title: Investigation of the freely available easy-to-use software’ EZR’ for medical statistics publication-title: Bone Marrow Transplant doi: 10.1038/bmt.2012.244 – volume: 33 start-page: 2507 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0370 article-title: Novel higher-order epigenetic regulation of the Bdnf gene upon seizures publication-title: J Neurosci doi: 10.1523/JNEUROSCI.1085-12.2013 – volume: 11 start-page: 242 year: 2010 ident: 10.1016/j.neures.2021.05.011_bib0230 article-title: Frozen robust multiarray analysis (fRMA) publication-title: Biostatistics doi: 10.1093/biostatistics/kxp059 – volume: 152 start-page: 584 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0300 article-title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation publication-title: Cell doi: 10.1016/j.cell.2013.01.009 – volume: 14 start-page: 207 year: 2016 ident: 10.1016/j.neures.2021.05.011_bib0350 article-title: Comparative Gene Expression Analysis of Mouse and Human Cardiac Maturation publication-title: Genomics Proteomics Bioinformatics doi: 10.1016/j.gpb.2016.04.004 – volume: 200 start-page: 605 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0075 article-title: Lamin B1 fluctuations have differential effects on cellular proliferation and senescence publication-title: J Cell Biol doi: 10.1083/jcb.201206121 – volume: 34 start-page: 1 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0015 article-title: Networking in the nucleus: a spotlight on LEM-domain proteins publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2015.03.005 – volume: 22 start-page: 832 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0050 article-title: Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin publication-title: Genes Dev doi: 10.1101/gad.1652708 – volume: 276 start-page: 7320 year: 2001 ident: 10.1016/j.neures.2021.05.011_bib0295 article-title: Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis publication-title: J Biol Chem doi: 10.1074/jbc.M008363200 – volume: 84 start-page: 131 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0115 article-title: Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation publication-title: Annu Rev Biochem doi: 10.1146/annurev-biochem-060614-034115 – volume: 110 start-page: 542 year: 2002 ident: 10.1016/j.neures.2021.05.011_bib0220 article-title: Intranuclear relocation of the Plc beta3 sequence in cerebellar purkinje neurons: temporal association with de novo expression during development publication-title: Chromosoma doi: 10.1007/s00412-001-0179-8 – volume: 7 start-page: 64 year: 2006 ident: 10.1016/j.neures.2021.05.011_bib0150 article-title: Per cell" normalization method for mRNA measurement by quantitative PCR and microarrays publication-title: BMC Genomics doi: 10.1186/1471-2164-7-64 – volume: 142 start-page: 2088 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0310 article-title: Neuronal polarization publication-title: Development doi: 10.1242/dev.114454 – volume: 7 start-page: 4897 year: 2017 ident: 10.1016/j.neures.2021.05.011_bib0210 article-title: Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis publication-title: Sci Rep doi: 10.1038/s41598-017-05078-6 – volume: 155 start-page: 780 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0280 article-title: Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cells publication-title: Neuroscience doi: 10.1016/j.neuroscience.2008.06.039 – volume: 27 start-page: 1800 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0275 article-title: Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence publication-title: Genes Dev doi: 10.1101/gad.217281.113 – volume: 144 start-page: 111 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0185 article-title: Chromatin at the nuclear periphery and the regulation of genome functions publication-title: Histochem Cell Biol doi: 10.1007/s00418-015-1346-y – volume: 8 start-page: 15098 year: 2017 ident: 10.1016/j.neures.2021.05.011_bib0100 article-title: Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation publication-title: Nat Commun doi: 10.1038/ncomms15098 – volume: 26 start-page: 69 year: 2014 ident: 10.1016/j.neures.2021.05.011_bib0025 article-title: Large-scale chromatin organization: the good, the surprising, and the still perplexing publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2013.10.002 – volume: 1 start-page: 2088 year: 2006 ident: 10.1016/j.neures.2021.05.011_bib0385 article-title: Inexpensive low-oxygen incubators publication-title: Nat Protoc doi: 10.1038/nprot.2006.374 – volume: 527 start-page: 105 year: 2015 ident: 10.1016/j.neures.2021.05.011_bib0070 article-title: Autophagy mediates degradation of nuclear lamina publication-title: Nature doi: 10.1038/nature15548 – volume: 10 start-page: 981 year: 2000 ident: 10.1016/j.neures.2021.05.011_bib0155 article-title: Dendritic anomalies in disorders associated with mental retardation publication-title: Cereb Cortex doi: 10.1093/cercor/10.10.981 – volume: 58 start-page: 34 year: 2004 ident: 10.1016/j.neures.2021.05.011_bib0005 article-title: Role of CRMP-2 in neuronal polarity publication-title: J Neurobiol doi: 10.1002/neu.10269 – volume: 9 year: 2014 ident: 10.1016/j.neures.2021.05.011_bib0160 article-title: Expression profiling of RNA transcripts during neuronal maturation and ischemic injury publication-title: PLoS One doi: 10.1371/journal.pone.0103525 – volume: 120 start-page: 210 year: 2012 ident: 10.1016/j.neures.2021.05.011_bib0165 article-title: Brain-derived neurotrophic factor uses CREB and Egr3 to regulate NMDA receptor levels in cortical neurons publication-title: J Neurochem doi: 10.1111/j.1471-4159.2011.07555.x – volume: 152 start-page: 1209 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0235 article-title: The cell biology of genomes: bringing the double helix to life publication-title: Cell doi: 10.1016/j.cell.2013.02.048 – volume: 14 start-page: 563 year: 2009 ident: 10.1016/j.neures.2021.05.011_bib0305 article-title: Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer publication-title: Mol Psychiatry doi: 10.1038/mp.2009.2 – volume: 31 start-page: 5723 year: 2003 ident: 10.1016/j.neures.2021.05.011_bib0330 article-title: Enhanced gene activation by Notch and BMP signaling cross-talk publication-title: Nucleic Acids Res doi: 10.1093/nar/gkg778 – volume: 31 start-page: 477 year: 1997 ident: 10.1016/j.neures.2021.05.011_bib0020 article-title: Egr transcription factors in the nervous system publication-title: Neurochem Int doi: 10.1016/S0197-0186(96)00136-2 – volume: 28 start-page: 54 year: 2014 ident: 10.1016/j.neures.2021.05.011_bib0255 article-title: Nucleolus and nuclear periphery: velcro for heterochromatin publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2014.03.001 – volume: 256 start-page: 131 year: 2000 ident: 10.1016/j.neures.2021.05.011_bib0215 article-title: Nuclear topology of murine, cerebellar Purkinje neurons: changes as a function of development publication-title: Exp Cell Res doi: 10.1006/excr.1999.4793 – volume: 25 start-page: 10286 year: 2005 ident: 10.1016/j.neures.2021.05.011_bib0190 article-title: The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors publication-title: Mol Cell Biol doi: 10.1128/MCB.25.23.10286-10300.2005 – volume: 452 start-page: 243 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0270 article-title: Transcriptional repression mediated by repositioning of genes to the nuclear lamina publication-title: Nature doi: 10.1038/nature06727 – volume: 22 start-page: 489 year: 2008 ident: 10.1016/j.neures.2021.05.011_bib0315 article-title: Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP publication-title: Genes Dev doi: 10.1101/gad.1634608 – volume: 21 start-page: 1954 year: 2012 ident: 10.1016/j.neures.2021.05.011_bib0355 article-title: Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice publication-title: Hum Mol Genet doi: 10.1093/hmg/dds005 – volume: 14 start-page: 67 year: 2013 ident: 10.1016/j.neures.2021.05.011_bib0030 article-title: The spatial organization of the human genome publication-title: Annu Rev Genomics Hum Genet doi: 10.1146/annurev-genom-091212-153515 – volume: 296 start-page: 158 year: 2002 ident: 10.1016/j.neures.2021.05.011_bib0180 article-title: Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development publication-title: Science doi: 10.1126/science.1068768 – volume: 104 start-page: 2815 year: 2007 ident: 10.1016/j.neures.2021.05.011_bib0390 article-title: Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0610765104 – volume: 2 start-page: 178 year: 2009 ident: 10.1016/j.neures.2021.05.011_bib0200 article-title: miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination publication-title: Dis Model Mech doi: 10.1242/dmm.001065 |
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| Title | Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons |
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