Multi-antigen serology and a diagnostic algorithm for the detection of arbovirus infections as novel tools for arbovirus preparedness in southeast Europe (MERMAIDS-ARBO): a prospective observational study - Kasbergen, Louella M R; de Bruin, Erwin; Chandler, Felicity; Sigfrid, Louise; Chan, Xin Hui S; Hookham, Lauren; Wei, Jia; Chen, Siyu; Charrel, Remi N; Corman, Victor M; Reusken, Chantal; Loens, Katherine; et al. (The Lancet infectious diseases, 2025)
Keywords: Adolescent; Adult; Aged; Algorithms; Antibodies; Antibodies, Viral - blood; Antigens; Antigens, Viral - blood; Antigens, Viral - immunology; Aquatic insects; Arachnids; Arbovirus Infections - diagnosis; Arbovirus Infections - epidemiology; Arbovirus Infections - virology; Arboviruses - immunology; Arboviruses - isolation & purification; Bacterial infections; Climate change; Climate effects; Crimean hemorrhagic fever; Differential diagnosis; Encephalitis; Europe - epidemiology; Female; Fever; Geography; Hemorrhagic Fever Virus, Crimean-Congo - immunology; Hospitals; Humans; Immunofluorescence; Immunoglobulin G; Immunoglobulin M; Infections; Infectious diseases; Insect bites; Insects; Male; Men; Middle Aged; Mosquitoes; Observational studies; Patients; Prospective Studies; Protein arrays; Proteins; Public health; Reactivity; Regulatory approval; Research ethics; Risk factors; Samples; Sampling; Serologic Tests; Serology; Surveillance; Thermal cycling; Tick-borne encephalitis; Translations; Vector-borne diseases; Viruses; West Nile virus; West Nile virus - immunology; Young Adult; Europe; Greece; Romania; Kosovo; Bosnia-Hercegovina; Serbia; Germany; Croatia; Albania