Current status of optical fiber biosensor based on surface plasmon resonance

• Published in: Biosensors & bioelectronics Vol. 142; p. 111505
• Main Authors: Zhao, Yong, Tong, Rui-jie, Xia, Feng, Peng, Yun
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.10.2019
• Subjects: Animals; Biosensor; biosensors; Equipment Design; Fiber Optic Technology - instrumentation; Fiber Optic Technology - methods; fiber optics; food safety; Humans; medicine; Optical fiber biosensor; Optical fiber grating; Optical Fibers; prototypes; Surface plasmon resonance; Surface Plasmon Resonance - instrumentation; Surface Plasmon Resonance - methods; Optical fiber grating; Surface plasmon resonance; Optical fiber biosensor; Biosensor
• ISSN: 0956-5663; 1873-4235; 1873-4235
• DOI: 10.1016/j.bios.2019.111505

Surface plasmon resonance (SPR) technology has effectively bolstered optic fiber sensing in fields of life science, clinical diagnosis, medicine, food safety and so on. The current review outlines the research status of fiber optic biosensor based on SPR, and the merits of optical fiber sensor and the development of optical fiber sensor based on SPR are completely covered. An in-depth review of four devices for generating SPR is presented, and optical fiber is finally adopted for a substrate to generate SPR. Different prototypes of optical fiber biosensor based on SPR are meticulously outlined: optical fiber grating biosensor based on SPR and optical fiber structured type biosensor based on SPR, and representative instances from literature are presented to verify the latest advancements in this potentially valuable research avenue. In addition, the sensing performance of different optical fiber structured type biosensor based on SPR are compared. What's more, simultaneous multi-parameter detection and improvement of sensitivity are discussed and summarized. The article concludes identify key challenges and develop orientation of optical fiber biosensor based on SPR. •This paper reviews the research status of fiber optic biosensors based on SPR.•Firstly, the SPR generation methods are systematically summarized.•The fiber grating biosensor and the optical fiber biosensor which can produce SPR effect are analyzed.•The double or multi-parameter measurement of SPR-based optical fiber biosensor is analyzed.