The two-stage detection-after-segmentation model improves the accuracy of identifying subdiaphragmatic lesions

• Published in: Scientific reports Vol. 14; no. 1; pp. 25414 - 13
• Main Authors: Chen, Chih-Hsiung, Hsu, Steven H., Hsieh, Kuang-Yu, Huang, Kuo-En, Lai, Hsien-Yung
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.10.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114/1564; 631/114/2397; 692/4020/2199; Abdomen; Abdomen - diagnostic imaging; Abdomen - pathology; Accuracy; Algorithms; Humanities and Social Sciences; Humans; Image processing; Image Processing, Computer-Assisted - methods; Lesions; multidisciplinary; Radiographic Image Interpretation, Computer-Assisted - methods; Radiography, Thoracic - methods; Science; Science (multidisciplinary); Segmentation
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-76450-6

Chest X-rays (CXRs) are primarily used to detect lung lesions. While the abdominal portion of CXRs can sometimes reveal critical conditions, research in this area is limited. To address this, we introduce a two-stage architecture that separates the abdominal region from the CXR and detects abdominal lesions using a specialized dataset. We compared the performance of our method on whole CXRs versus isolated abdominal regions. First, we created masks for the right upper quadrant (RUQ), left upper quadrant (LUQ), and upper abdomen (ABD) regions and trained corresponding segmentation models for each area. For detecting abdominal lesions, we curated a dataset of 5,996 images, categorized into 19 classes based on anatomical locations, air patterns, and levels of stomach or bowel dilation. The detection process was initially conducted on the original images, followed by the three regional areas, RUQ, LUQ, and ABD, extracted by the segmentation models. The results showed that the detection model trained on the entire ABD region achieved the highest accuracy, followed closely by the RUQ and LUQ models. In contrast, the CXR model had the lowest accuracy. This study highlights that the two-stage architecture effectively manages distinct segmentation and detection tasks in CXRs, offering a promising avenue for more accurate diagnoses. It also suggests that an optimal ratio between the sizes of the target lesions and the input images may exist.