A microdialysis method to measure in vivo hydrogen peroxide and superoxide in various rodent tissues
Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utiliz...
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| Published in | Methods (San Diego, Calif.) Vol. 109; pp. 131 - 140 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
15.10.2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1046-2023 1095-9130 1095-9130 |
| DOI | 10.1016/j.ymeth.2016.07.012 |
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| Abstract | Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H2O2) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H2O2 and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress. |
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| AbstractList | Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H2O2) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H2O2 and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress. Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H2O2) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H2O2 and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress.Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H2O2) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H2O2 and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress. Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H 2 O 2 ) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H 2 O 2 and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress. Reactive oxygen species (ROS) play a critical role in cell signaling and disease pathogenesis. Despite their biological importance, assessment of ROS often involves measurement of indirect byproducts or measurement of ROS from excised tissue. Herein, we describe a microdialysis technique that utilizes the Amplex Ultrared assay to directly measure hydrogen peroxide (H O ) and superoxide in tissue of living, anesthetized rats and mice. We demonstrate the application of this methodology in the penis, adipose tissue, skeletal muscle, kidney, and liver. We provide data demonstrating the impact of important methodological considerations such as membrane length, perfusion rate, and time-dependence upon probe insertion. In this report, we provide a complete list of equipment, troubleshooting tips, and suggestions for implementing this technique in a new system. The data herein demonstrate the feasibility of measuring both in vivo H O and superoxide in the extracellular environment of various rodent tissues, providing a technique with potential application to a vast array of disease states which are subject to oxidative stress. |
| Author | La Favor, Justin D. Burnett, Arthur L. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27452801$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/0891-5849(93)90044-U 10.1093/geronj/11.3.298 10.1152/ajpregu.2001.280.1.R100 10.1161/01.RES.74.6.1141 10.1002/hep.1840160225 10.3109/10715761003709802 10.1016/S0140-6736(94)92211-X 10.1089/ars.2007.1869 10.1161/01.HYP.0000101968.09376.79 10.1007/978-1-4939-2257-4_22 10.1161/01.HYP.0000258594.87211.6b 10.33549/physiolres.933254 10.1042/CS20120470 10.1161/01.HYP.37.2.547 10.1074/jbc.M111.309062 10.1111/j.1471-4159.1992.tb09346.x 10.1152/ajpheart.00247.2014 10.1152/japplphysiol.91485.2008 10.1016/S0021-9258(18)63504-5 10.1016/0160-5402(89)90012-0 10.1016/j.freeradbiomed.2015.11.011 10.1016/j.etap.2006.09.003 10.1089/ars.2012.4886 10.1152/ajpregu.00049.2013 10.1006/abbi.1997.9766 10.1186/1475-2840-12-142 10.1152/ajpregu.00322.2006 10.1093/carcin/21.5.983 10.1128/MCB.00677-14 10.1016/0891-5849(90)90131-2 10.1111/jsm.12391 10.1080/10715760410001659773 10.1016/j.freeradbiomed.2009.07.014 10.1371/journal.pone.0140728 10.1006/abbi.1999.1579 10.1111/jsm.12001 10.1152/ajpendo.00456.2007 10.1016/j.freeradbiomed.2011.03.016 10.1172/JCI73957 10.1093/cvr/cvq355 10.1016/0160-5402(89)90011-9 10.1186/1758-5996-3-17 10.1007/s00216-011-5451-z 10.1152/ajpheart.00987.2008 10.33549/physiolres.932587 10.1111/jsm.12682 10.1172/JCI21625 10.3109/01480545.2012.710629 10.1016/j.cca.2007.01.028 10.1113/jphysiol.2013.254193 10.1016/0891-5849(91)90192-6 10.1016/S0022-1759(96)00244-X 10.1016/0968-0004(79)90203-2 10.2174/0929867043455567 10.1006/abio.1997.2391 10.1152/japplphysiol.01448.2010 10.1172/JCI37048 10.1016/j.freeradbiomed.2016.03.027 10.1016/j.freeradbiomed.2012.01.033 |
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| Keywords | Oxidative stress Liver HRP Redox SOD TBARS MDA H2O2 Ang II ROS Cat ROS detection Amplex Red HO |
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| References | Fariña, García, Alzamendi, Giovambattista, Marra, Spinedi, Gagliardino (b0130) 2013; 125 Spasojevic, Liochev, Fridovich (b0055) 2000; 373 Musicki, Bivalacqua, Champion, Burnett (b0125) 2014; 11 Miwa S, Treumann, Bell, Vistoli, Nelson, Hay, von Zglinicki (b0210) 2016; 90 Liochev, Fridovich (b0050) 1997; 337 Kamimura, Gaal, Britton, Bacon, Triadafilopoulos, Tsukamoto (b0170) 1992; 16 Dikalov, Harrison (b0295) 2014; 20 Sullivan, Sasser, Pollock (b0090) 2007; 292 Zhou, Diwu, Panchuk-Voloshina, Haugland (b0070) 1997; 253 Janero (b0020) 1990; 9 Pauling (b0015) 1979; 4 Griendling, Minieri, Ollerenshaw, Alexander (b0265) 1994; 74 Halliwell (b0010) 1994; 344 López, Salom, Arregui, Valero, Fenoy (b0270) 2003; 42 Dykstra, Hsiao, Morrison, Bungay, Mefford, Scully, Dedrick (b0225) 1992; 58 Dikalov, Griendling, Harrison (b0045) 2007; 49 Ligor, Olszowy, Buszewski (b0025) 2012; 402 Dębski, Smulik, Zielonka, Michaŀowski, Jakubowska, Dębowska, Adamus, Marcinek, Kalyanaraman, Sikora (b0280) 2016; 95 Veskoukis, Nikolaidis, Kyparos, Kouretas (b0230) 2009; 47 Gentric, Maillet, Paradis, Couton, L’Hermitte, Panasyuk, Fromenty, Celton-Morizur, Desdouets (b0160) 2015; 125 Faulkner, Fridovich (b0035) 1993; 15 Fisher-Wellman, Mattox, Thayne, Katunga, La Favor, Neufer, Hickner, Wingard, Anderson (b0100) 2013; 591 Vokurková, Rauchová, Řezáčová, Vaněčková, Zicha (b0150) 2015; 64 Zou, Li, Cowley (b0155) 2001; 37 Meakin, Chowdhry, Sharma, Ashford, Walsh, McCrimmon, Dinkova-Kostova, Dillon, Hayes, Ashford (b0175) 2014; 34 Lushchak, Lushchak, Mota, Hermes-Lima (b0245) 2001; 280 Mohanty, Jaffe, Schulman, Raible (b0065) 1997; 202 Amberg, Lindefors (b0185) 1989; 22 Pohanka, Stetina, Svobodova, Ruttkay-Nedecky, Jilkova, Sochor, Sobotka, Adam, Kizek (b0235) 2013; 36 La Favor, Kraus, Carrithers, Roseno, Gavin, Hickner (b0215) 2014; 307 Esterbauer, Schaur, Zollner (b0260) 1991; 11 Ormsbee, Choi, Medlin, Geyer, Trantham, Dubis, Hickner (b0220) 2009; 106 Medow, Bamji, Clarke, Ocon, Stewart (b0275) 2011; 111 Patel, Chen, Das, Kavdia (b0075) 2013; 12 Krumschnabel, Fontana-Ayoub, Sumbalova, Heidler, Gauper, Fasching, Gnaiger (b0200) 2015; 1264 Hensley, Kotake, Sang, Pye, Wallis, Kolker, Tabatabaie, Stewart, Konishi, Nakae, Floyd (b0165) 2000; 21 Silva, Leiria, Alexandre, Davel, Mónica, De Nucci, Antunes (b0115) 2014; 11 Noeman, Hamooda, Baalash (b0250) 2011; 3 La Favor, Anderson, Dawkins, Hickner, Wingard (b0105) 2013; 305 La Favor, Anderson, Hickner, Wingard (b0110) 2013; 10 Yan, Zhao, Suo, Liu, Zhao (b0135) 2012; 52 Possamai, Fortunato, Feier, Agostinho, Quevedo, Wilhelm Filho, Dal-Pizzol (b0255) 2007; 23 Lykkesfeldt (b0030) 2007; 380 Daiber, Oelze, August, Wendt, Sydow, Wieboldt, Kleschyov, Munzel (b0040) 2004; 38 Wei, Sowers, Clark, Li, Ferrario, Stump (b0145) 2008; 294 Lindefors, Amberg, Ungerstedt (b0190) 1989; 22 Kojo (b0240) 2004; 11 Harman (b0005) 1956; 11 Dixon, Heath, Kim, Suh, Hagen (b0290) 2008; 10 McCord, Fridovich (b0180) 1969; 244 Zielonka, Zielonka, Sikora, Adamus, Joseph, Hardy, Ouari, Dranka, Kalyanaraman (b0285) 2012; 287 Zhao, Ranguelova, Jiang, Mason (b0205) 2011; 51 La Favor, Anderson, Hickner (b0195) 2014; 63 Miller, Drummond, De Silva, Mast, Hickey, Williams, Broughton, Sobey (b0085) 2009; 296 Chen, Zhong, Xu, Chen, Wang (b0060) 2010; 44 Anderson, Lustig, Boyle, Woodlief, Kane, Lin, Price, Kang, Rabinovitch, Szeto, Houmard, Cortright, Wasserman, Neufer (b0095) 2009; 119 Huang, Chin, Chen, Shindel, Ho, Lin, Shi (b0120) 2015; 10 Schreiner, Kumerz, Gesslbauer, Schachner, Joa, Erker, Atanasov, Heiss, Dirsch (b0080) 2011; 90 Furukawa, Fujita, Shimabukuro, Iwaki, Yamada, Nakajima, Nakayama, Makishima, Matsuda, Shimomura (b0140) 2004; 114 La Favor (10.1016/j.ymeth.2016.07.012_b0110) 2013; 10 McCord (10.1016/j.ymeth.2016.07.012_b0180) 1969; 244 Vokurková (10.1016/j.ymeth.2016.07.012_b0150) 2015; 64 Miwa S (10.1016/j.ymeth.2016.07.012_b0210) 2016; 90 Griendling (10.1016/j.ymeth.2016.07.012_b0265) 1994; 74 Krumschnabel (10.1016/j.ymeth.2016.07.012_b0200) 2015; 1264 Yan (10.1016/j.ymeth.2016.07.012_b0135) 2012; 52 Patel (10.1016/j.ymeth.2016.07.012_b0075) 2013; 12 Fariña (10.1016/j.ymeth.2016.07.012_b0130) 2013; 125 Lindefors (10.1016/j.ymeth.2016.07.012_b0190) 1989; 22 La Favor (10.1016/j.ymeth.2016.07.012_b0105) 2013; 305 Silva (10.1016/j.ymeth.2016.07.012_b0115) 2014; 11 Liochev (10.1016/j.ymeth.2016.07.012_b0050) 1997; 337 Possamai (10.1016/j.ymeth.2016.07.012_b0255) 2007; 23 Lykkesfeldt (10.1016/j.ymeth.2016.07.012_b0030) 2007; 380 Zou (10.1016/j.ymeth.2016.07.012_b0155) 2001; 37 Zhou (10.1016/j.ymeth.2016.07.012_b0070) 1997; 253 Hensley (10.1016/j.ymeth.2016.07.012_b0165) 2000; 21 Zhao (10.1016/j.ymeth.2016.07.012_b0205) 2011; 51 Miller (10.1016/j.ymeth.2016.07.012_b0085) 2009; 296 Musicki (10.1016/j.ymeth.2016.07.012_b0125) 2014; 11 Halliwell (10.1016/j.ymeth.2016.07.012_b0010) 1994; 344 Dixon (10.1016/j.ymeth.2016.07.012_b0290) 2008; 10 La Favor (10.1016/j.ymeth.2016.07.012_b0195) 2014; 63 Spasojevic (10.1016/j.ymeth.2016.07.012_b0055) 2000; 373 Dikalov (10.1016/j.ymeth.2016.07.012_b0295) 2014; 20 Pauling (10.1016/j.ymeth.2016.07.012_b0015) 1979; 4 Wei (10.1016/j.ymeth.2016.07.012_b0145) 2008; 294 Schreiner (10.1016/j.ymeth.2016.07.012_b0080) 2011; 90 Sullivan (10.1016/j.ymeth.2016.07.012_b0090) 2007; 292 Amberg (10.1016/j.ymeth.2016.07.012_b0185) 1989; 22 Furukawa (10.1016/j.ymeth.2016.07.012_b0140) 2004; 114 Kojo (10.1016/j.ymeth.2016.07.012_b0240) 2004; 11 Mohanty (10.1016/j.ymeth.2016.07.012_b0065) 1997; 202 Janero (10.1016/j.ymeth.2016.07.012_b0020) 1990; 9 Meakin (10.1016/j.ymeth.2016.07.012_b0175) 2014; 34 López (10.1016/j.ymeth.2016.07.012_b0270) 2003; 42 Esterbauer (10.1016/j.ymeth.2016.07.012_b0260) 1991; 11 Medow (10.1016/j.ymeth.2016.07.012_b0275) 2011; 111 Ormsbee (10.1016/j.ymeth.2016.07.012_b0220) 2009; 106 Dębski (10.1016/j.ymeth.2016.07.012_b0280) 2016; 95 Kamimura (10.1016/j.ymeth.2016.07.012_b0170) 1992; 16 Daiber (10.1016/j.ymeth.2016.07.012_b0040) 2004; 38 Ligor (10.1016/j.ymeth.2016.07.012_b0025) 2012; 402 Noeman (10.1016/j.ymeth.2016.07.012_b0250) 2011; 3 Zielonka (10.1016/j.ymeth.2016.07.012_b0285) 2012; 287 Fisher-Wellman (10.1016/j.ymeth.2016.07.012_b0100) 2013; 591 Dykstra (10.1016/j.ymeth.2016.07.012_b0225) 1992; 58 Harman (10.1016/j.ymeth.2016.07.012_b0005) 1956; 11 Faulkner (10.1016/j.ymeth.2016.07.012_b0035) 1993; 15 Dikalov (10.1016/j.ymeth.2016.07.012_b0045) 2007; 49 Lushchak (10.1016/j.ymeth.2016.07.012_b0245) 2001; 280 Chen (10.1016/j.ymeth.2016.07.012_b0060) 2010; 44 Gentric (10.1016/j.ymeth.2016.07.012_b0160) 2015; 125 La Favor (10.1016/j.ymeth.2016.07.012_b0215) 2014; 307 Huang (10.1016/j.ymeth.2016.07.012_b0120) 2015; 10 Veskoukis (10.1016/j.ymeth.2016.07.012_b0230) 2009; 47 Pohanka (10.1016/j.ymeth.2016.07.012_b0235) 2013; 36 Anderson (10.1016/j.ymeth.2016.07.012_b0095) 2009; 119 22015476 - Anal Bioanal Chem. 2012 Mar;402(7):2233-48 22978713 - Antioxid Redox Signal. 2014 Jan 10;20(2):372-82 22139901 - J Biol Chem. 2012 Jan 27;287(5):2984-95 8990275 - Arch Biochem Biophys. 1997 Jan 1;337(1):115-20 21071431 - Cardiovasc Res. 2011 Apr 1;90(1):140-7 1639354 - Hepatology. 1992 Aug;16(2):448-53 24951753 - Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H524-32 23170997 - J Sex Med. 2013 Mar;10 (3):694-703 1937131 - Free Radic Biol Med. 1991;11(1):81-128 19028794 - Am J Physiol Heart Circ Physiol. 2009 Jan;296(1):H220-5 22330066 - Free Radic Biol Med. 2012 May 1;52(9):1648-57 20370560 - Free Radic Res. 2010 Jun;44(6):587-604 19188683 - J Clin Invest. 2009 Mar;119(3):573-81 16917021 - Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R764-8 10783322 - Carcinogenesis. 2000 May;21(5):983-9 23761637 - Am J Physiol Regul Integr Comp Physiol. 2013 Aug 15;305(4):R423-34 21419845 - Free Radic Biol Med. 2011 Jul 1;51(1):153-9 9367498 - Anal Biochem. 1997 Nov 15;253(2):162-8 1738000 - J Neurochem. 1992 Mar;58(3):931-40 26491965 - PLoS One. 2015 Oct 22;10(10):e0140728 15599400 - J Clin Invest. 2004 Dec;114(12):1752-61 17336279 - Clin Chim Acta. 2007 May 1;380(1-2):50-8 2586111 - J Pharmacol Methods. 1989 Nov;22(3):141-56 11230333 - Hypertension. 2001 Feb;37(2 Pt 2):547-53 7915779 - Lancet. 1994 Sep 10;344(8924):721-4 25621497 - J Clin Invest. 2015 Mar 2;125(3):981-92 23384123 - Clin Sci (Lond). 2013 Jul 1;125(2):87-97 24564604 - Physiol Res. 2014;63(3):387-92 22947058 - Drug Chem Toxicol. 2013 Jul;36(3):270-6 26713567 - Physiol Res. 2015 ;64(6):849-56 21436462 - J Appl Physiol (1985). 2011 Jul;111(1):20-6 5389100 - J Biol Chem. 1969 Nov 25;244(22):6049-55 25196910 - J Sex Med. 2014 Nov;11(11):2661-70 24251665 - J Sex Med. 2014 Feb;11(2):424-30 25631019 - Methods Mol Biol. 2015;1264:245-61 9107302 - J Immunol Methods. 1997 Mar 28;202(2):133-41 21812977 - Diabetol Metab Syndr. 2011 Aug 03;3(1):17 17296874 - Hypertension. 2007 Apr;49(4):717-27 14597645 - Hypertension. 2003 Dec;42(6):1150-6 13332224 - J Gerontol. 1956 Jul;11(3):298-300 15129734 - Free Radic Res. 2004 Mar;38(3):259-69 18205546 - Antioxid Redox Signal. 2008 May;10(5):963-72 21783758 - Environ Toxicol Pharmacol. 2007 Mar;23(2):198-204 23613536 - J Physiol. 2013 Jul 15;591(14):3471-86 8187280 - Circ Res. 1994 Jun;74(6):1141-8 8225026 - Free Radic Biol Med. 1993 Oct;15(4):447-51 11124139 - Am J Physiol Regul Integr Comp Physiol. 2001 Jan;280(1):R100-7 19616614 - Free Radic Biol Med. 2009 Nov 15;47(10):1371-4 19265063 - J Appl Physiol (1985). 2009 May;106(5):1529-37 15078165 - Curr Med Chem. 2004 Apr;11(8):1041-64 26577176 - Free Radic Biol Med. 2016 Jan;90:173-83 18073321 - Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E345-51 24958099 - Mol Cell Biol. 2014 Sep;34(17):3305-20 2079232 - Free Radic Biol Med. 1990;9(6):515-40 2586112 - J Pharmacol Methods. 1989 Nov;22(3):157-83 27021961 - Free Radic Biol Med. 2016 Jun;95:323-32 10620371 - Arch Biochem Biophys. 2000 Jan 15;373(2):447-50 24093550 - Cardiovasc Diabetol. 2013 Oct 05;12 :142 |
| References_xml | – volume: 21 start-page: 983 year: 2000 end-page: 989 ident: b0165 article-title: Dietary choline restriction causes complex I dysfunction and increased H publication-title: Carcinogenesis – volume: 38 start-page: 259 year: 2004 end-page: 269 ident: b0040 article-title: Detection of superoxide and peroxynitrite in model systems and mitochondria by the luminol analogue L-012 publication-title: Free Radical Res. – volume: 36 start-page: 270 year: 2013 end-page: 276 ident: b0235 article-title: Sulfur mustard causes oxidative stress and depletion of antioxidants in muscles, livers, and kidneys of Wistar rats publication-title: Drug Chem. Toxicol. – volume: 125 start-page: 981 year: 2015 end-page: 992 ident: b0160 article-title: Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease publication-title: J. Clin. Invest. – volume: 114 start-page: 1752 year: 2004 end-page: 1761 ident: b0140 article-title: Increased oxidative stress in obesity and its impact on metabolic syndrome publication-title: J. Clin. Invest. – volume: 16 start-page: 448 year: 1992 end-page: 453 ident: b0170 article-title: Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxidation with liver fibrogenesis publication-title: Hepatology – volume: 1264 start-page: 245 year: 2015 end-page: 261 ident: b0200 article-title: Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production publication-title: Methods Mol. Biol. – volume: 51 start-page: 153 year: 2011 end-page: 159 ident: b0205 article-title: Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red publication-title: Free Radical Biol. Med. – volume: 3 start-page: 17 year: 2011 ident: b0250 article-title: Biochemical study of oxidative stress markers in the liver, kidney and heart of high fat diet induced obesity in rats publication-title: Diabetol. Metab. Syndr. – volume: 292 start-page: R764 year: 2007 end-page: R768 ident: b0090 article-title: Sexual dimorphism in oxidant status in spontaneously hypertensive rats publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. – volume: 74 start-page: 1141 year: 1994 end-page: 1148 ident: b0265 article-title: Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells publication-title: Circ. Res. – volume: 52 start-page: 1648 year: 2012 end-page: 1657 ident: b0135 article-title: Green tea catechins ameliorate adipose insulin resistance by improving oxidative stress publication-title: Free Radical Biol. Med. – volume: 305 start-page: R423 year: 2013 end-page: R434 ident: b0105 article-title: Exercise prevents Western diet-associated erectile dysfunction and coronary artery endothelial dysfunction: response to acute apocynin and sepiapterin treatment publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. – volume: 11 start-page: 424 year: 2014 end-page: 430 ident: b0125 article-title: Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis publication-title: J. Sex. Med. – volume: 63 start-page: 387 year: 2014 end-page: 392 ident: b0195 article-title: Novel method for detection of reactive oxygen species in vivo in human skeletal muscle publication-title: Physiol. Res. – volume: 22 start-page: 157 year: 1989 end-page: 183 ident: b0185 article-title: Intracerebral microdialysis: II. mathematical studies of diffusion kinetics publication-title: J. Pharmacol. Methods – volume: 11 start-page: 81 year: 1991 end-page: 128 ident: b0260 article-title: Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes publication-title: Free Radical Biol. Med. – volume: 337 start-page: 115 year: 1997 end-page: 120 ident: b0050 article-title: Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production publication-title: Arch. Biochem. Biophys. – volume: 591 start-page: 3471 year: 2013 end-page: 3486 ident: b0100 article-title: Novel role for thioredoxin reductase-2 in mitochondrial redox adaptations to obesogenic diet and exercise in heart and skeletal muscle publication-title: J. Physiol. – volume: 47 start-page: 1371 year: 2009 end-page: 1374 ident: b0230 article-title: Blood reflects tissue oxidative stress depending on biomarker and tissue studies publication-title: Free Radical Biol. Med. – volume: 307 start-page: H524 year: 2014 end-page: H532 ident: b0215 article-title: Sex differences with aging in nutritive skeletal muscle blood flow: impact of exercise training, nitric oxide, and α-adrenergic-mediated mechanisms publication-title: Am. J. Physiol. Heart Circ. Physiol. – volume: 280 start-page: R100 year: 2001 end-page: R107 ident: b0245 article-title: Oxidative stress and antioxidant defenses in goldfish publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. – volume: 90 start-page: 140 year: 2011 end-page: 147 ident: b0080 article-title: Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner publication-title: Cardiovasc. Res. – volume: 119 start-page: 573 year: 2009 end-page: 581 ident: b0095 article-title: Mitochondrial H publication-title: J. Clin. Invest. – volume: 111 start-page: 20 year: 2011 end-page: 26 ident: b0275 article-title: Reactive oxygen species (ROS) from NADPH and xanthine oxidase modulate the cutaneous local heating response in healthy humans publication-title: J. Appl. Physiol. – volume: 90 start-page: 173 year: 2016 end-page: 183 ident: b0210 article-title: Carboxylesterase converts Amplex red to resorufin: implications for mitochondrial H publication-title: Free Radical Biol. Med. – volume: 10 start-page: 694 year: 2013 end-page: 703 ident: b0110 article-title: Erectile dysfunction precedes coronary artery endothelial dysfunction in rats fed a high-fat, high-sucrose, Western pattern diet publication-title: J. Sex. Med. – volume: 9 start-page: 515 year: 1990 end-page: 540 ident: b0020 article-title: Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury publication-title: Free Radical Biol. Med. – volume: 11 start-page: 1041 year: 2004 end-page: 1064 ident: b0240 article-title: Vitamin C: basic metabolism and its function as an index of oxidative stress publication-title: Curr. Med. Chem. – volume: 253 start-page: 162 year: 1997 end-page: 168 ident: b0070 article-title: A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases publication-title: Anal. Biochem. – volume: 402 start-page: 2233 year: 2012 end-page: 2248 ident: b0025 article-title: Application of medical and analytical methods in Lyme borreliosis monitoring publication-title: Anal. Bioanal. Chem. – volume: 95 start-page: 323 year: 2016 end-page: 332 ident: b0280 article-title: Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies publication-title: Free Radical Biol. Med. – volume: 34 start-page: 3305 year: 2014 end-page: 3320 ident: b0175 article-title: Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance publication-title: Mol. Cell. Biol. – volume: 296 start-page: H220 year: 2009 end-page: H225 ident: b0085 article-title: NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2 publication-title: Am. J. Physiol. Heart Circ. Physiol. – volume: 37 start-page: 547 year: 2001 end-page: 553 ident: b0155 article-title: Production and actions of superoxide in the renal medulla publication-title: Hypertension – volume: 44 start-page: 587 year: 2010 end-page: 604 ident: b0060 article-title: 2′,7′-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: forty years of application and controversy publication-title: Free Radical Res. – volume: 373 start-page: 447 year: 2000 end-page: 450 ident: b0055 article-title: Lucigenin: redox potential in aqueous media and redox cycling with O publication-title: Arch. Biochem. Biophys. – volume: 125 start-page: 87 year: 2013 end-page: 97 ident: b0130 article-title: Antioxidant treatment prevents the development of fructose-induced abdominal adipose tissue dysfunction publication-title: Clin. Sci. (Lond). – volume: 11 start-page: 298 year: 1956 end-page: 300 ident: b0005 article-title: Aging: a theory based on free radical and radiation chemistry publication-title: J. Gerontol. – volume: 294 start-page: E345 year: 2008 end-page: E351 ident: b0145 article-title: Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kB activation via NADPH oxidase publication-title: Am. J. Physiol. Endocrinol. Metab. – volume: 202 start-page: 133 year: 1997 end-page: 141 ident: b0065 article-title: A highly sensitive fluorescent micro-assay of H publication-title: J. Immunol. Methods – volume: 244 start-page: 6049 year: 1969 end-page: 6055 ident: b0180 article-title: Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein) publication-title: J. Biol. Chem. – volume: 4 start-page: N270 year: 1979 end-page: N271 ident: b0015 article-title: The discovery of the superoxide radical publication-title: Trends Biochem. Sci. – volume: 49 start-page: 717 year: 2007 end-page: 727 ident: b0045 article-title: Measurement of reactive oxygen species in cardiovascular studies publication-title: Hypertension – volume: 11 start-page: 2661 year: 2014 end-page: 2670 ident: b0115 article-title: Prolonged therapy with the soluble guanylyl cyclase activator BAY 60–2770 restores the erectile function in obese mice publication-title: J. Sex. Med. – volume: 58 start-page: 931 year: 1992 end-page: 940 ident: b0225 article-title: Quantitative examination of tissue concentration profiles associated with microdialysis publication-title: J. Neurochem. – volume: 22 start-page: 141 year: 1989 end-page: 156 ident: b0190 article-title: Intracerebral microdialysis: I. experimental studies of diffusion kinetics publication-title: J. Pharmacol. Methods – volume: 20 start-page: 372 year: 2014 end-page: 382 ident: b0295 article-title: Methods for detection of mitochondrial and cellular reactive oxygen species publication-title: Antioxid. Redox Signal. – volume: 10 start-page: e0140728 year: 2015 ident: b0120 article-title: Chronic cigarette smoking impairs erectile function through increased oxidative stress and apoptosis, decreased nNOS, endothelial and smooth muscle contents in a rat model publication-title: PLoS ONE – volume: 106 start-page: 1529 year: 2009 end-page: 1537 ident: b0220 article-title: Regulation of fat metabolism during resistance exercise in sedentary lean and obese men publication-title: J. Appl. Physiol. – volume: 42 start-page: 1150 year: 2003 end-page: 1156 ident: b0270 article-title: Role of superoxide in modulating the renal effects of angiotensin II publication-title: Hypertension – volume: 344 start-page: 721 year: 1994 end-page: 724 ident: b0010 article-title: Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? publication-title: Lancet – volume: 15 start-page: 447 year: 1993 end-page: 451 ident: b0035 article-title: Luminol and lucigenin as detectors for O publication-title: Free Radical Biol. Med. – volume: 23 start-page: 198 year: 2007 end-page: 204 ident: b0255 article-title: Oxidative stress after acute and sub-chronic malathion intoxication in Wistar rats publication-title: Environ. Toxicol. Pharmacol. – volume: 12 start-page: 142 year: 2013 ident: b0075 article-title: Hyperglycemia induces differential change in oxidative stress at gene expression and functional levels in HUVEC and HMVEC publication-title: Cardiovasc. Diabetol. – volume: 64 start-page: 849 year: 2015 end-page: 856 ident: b0150 article-title: NADPH oxidase activity and reactive oxygen species production in brain and kidney of adult male hypertensive Ren-2 transgenic rats publication-title: Physiol. Res. – volume: 10 start-page: 963 year: 2008 end-page: 972 ident: b0290 article-title: Assessment of endoplasmic reticulum glutathione redox status is confounded by extensive ex vivo oxidation publication-title: Antioxid. Redox Signal. – volume: 380 start-page: 50 year: 2007 end-page: 58 ident: b0030 article-title: Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking publication-title: Clin. Chim. Acta – volume: 287 start-page: 2984 year: 2012 end-page: 2995 ident: b0285 article-title: Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses publication-title: J. Biol. Chem. – volume: 15 start-page: 447 year: 1993 ident: 10.1016/j.ymeth.2016.07.012_b0035 article-title: Luminol and lucigenin as detectors for O2- publication-title: Free Radical Biol. Med. doi: 10.1016/0891-5849(93)90044-U – volume: 11 start-page: 298 year: 1956 ident: 10.1016/j.ymeth.2016.07.012_b0005 article-title: Aging: a theory based on free radical and radiation chemistry publication-title: J. Gerontol. doi: 10.1093/geronj/11.3.298 – volume: 280 start-page: R100 year: 2001 ident: 10.1016/j.ymeth.2016.07.012_b0245 article-title: Oxidative stress and antioxidant defenses in goldfish Carassius auratus during anoxia and reoxygenation publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. doi: 10.1152/ajpregu.2001.280.1.R100 – volume: 74 start-page: 1141 year: 1994 ident: 10.1016/j.ymeth.2016.07.012_b0265 article-title: Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells publication-title: Circ. Res. doi: 10.1161/01.RES.74.6.1141 – volume: 16 start-page: 448 year: 1992 ident: 10.1016/j.ymeth.2016.07.012_b0170 article-title: Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxidation with liver fibrogenesis publication-title: Hepatology doi: 10.1002/hep.1840160225 – volume: 44 start-page: 587 year: 2010 ident: 10.1016/j.ymeth.2016.07.012_b0060 article-title: 2′,7′-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: forty years of application and controversy publication-title: Free Radical Res. doi: 10.3109/10715761003709802 – volume: 344 start-page: 721 year: 1994 ident: 10.1016/j.ymeth.2016.07.012_b0010 article-title: Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? publication-title: Lancet doi: 10.1016/S0140-6736(94)92211-X – volume: 10 start-page: 963 year: 2008 ident: 10.1016/j.ymeth.2016.07.012_b0290 article-title: Assessment of endoplasmic reticulum glutathione redox status is confounded by extensive ex vivo oxidation publication-title: Antioxid. Redox Signal. doi: 10.1089/ars.2007.1869 – volume: 42 start-page: 1150 year: 2003 ident: 10.1016/j.ymeth.2016.07.012_b0270 article-title: Role of superoxide in modulating the renal effects of angiotensin II publication-title: Hypertension doi: 10.1161/01.HYP.0000101968.09376.79 – volume: 1264 start-page: 245 year: 2015 ident: 10.1016/j.ymeth.2016.07.012_b0200 article-title: Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production publication-title: Methods Mol. Biol. doi: 10.1007/978-1-4939-2257-4_22 – volume: 49 start-page: 717 year: 2007 ident: 10.1016/j.ymeth.2016.07.012_b0045 article-title: Measurement of reactive oxygen species in cardiovascular studies publication-title: Hypertension doi: 10.1161/01.HYP.0000258594.87211.6b – volume: 64 start-page: 849 year: 2015 ident: 10.1016/j.ymeth.2016.07.012_b0150 article-title: NADPH oxidase activity and reactive oxygen species production in brain and kidney of adult male hypertensive Ren-2 transgenic rats publication-title: Physiol. Res. doi: 10.33549/physiolres.933254 – volume: 125 start-page: 87 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0130 article-title: Antioxidant treatment prevents the development of fructose-induced abdominal adipose tissue dysfunction publication-title: Clin. Sci. (Lond). doi: 10.1042/CS20120470 – volume: 37 start-page: 547 year: 2001 ident: 10.1016/j.ymeth.2016.07.012_b0155 article-title: Production and actions of superoxide in the renal medulla publication-title: Hypertension doi: 10.1161/01.HYP.37.2.547 – volume: 287 start-page: 2984 year: 2012 ident: 10.1016/j.ymeth.2016.07.012_b0285 article-title: Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.309062 – volume: 58 start-page: 931 year: 1992 ident: 10.1016/j.ymeth.2016.07.012_b0225 article-title: Quantitative examination of tissue concentration profiles associated with microdialysis publication-title: J. Neurochem. doi: 10.1111/j.1471-4159.1992.tb09346.x – volume: 307 start-page: H524 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0215 article-title: Sex differences with aging in nutritive skeletal muscle blood flow: impact of exercise training, nitric oxide, and α-adrenergic-mediated mechanisms publication-title: Am. J. Physiol. Heart Circ. Physiol. doi: 10.1152/ajpheart.00247.2014 – volume: 106 start-page: 1529 year: 2009 ident: 10.1016/j.ymeth.2016.07.012_b0220 article-title: Regulation of fat metabolism during resistance exercise in sedentary lean and obese men publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.91485.2008 – volume: 244 start-page: 6049 year: 1969 ident: 10.1016/j.ymeth.2016.07.012_b0180 article-title: Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein) publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(18)63504-5 – volume: 22 start-page: 157 year: 1989 ident: 10.1016/j.ymeth.2016.07.012_b0185 article-title: Intracerebral microdialysis: II. mathematical studies of diffusion kinetics publication-title: J. Pharmacol. Methods doi: 10.1016/0160-5402(89)90012-0 – volume: 90 start-page: 173 year: 2016 ident: 10.1016/j.ymeth.2016.07.012_b0210 article-title: Carboxylesterase converts Amplex red to resorufin: implications for mitochondrial H2O2 release assays publication-title: Free Radical Biol. Med. doi: 10.1016/j.freeradbiomed.2015.11.011 – volume: 23 start-page: 198 year: 2007 ident: 10.1016/j.ymeth.2016.07.012_b0255 article-title: Oxidative stress after acute and sub-chronic malathion intoxication in Wistar rats publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2006.09.003 – volume: 20 start-page: 372 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0295 article-title: Methods for detection of mitochondrial and cellular reactive oxygen species publication-title: Antioxid. Redox Signal. doi: 10.1089/ars.2012.4886 – volume: 305 start-page: R423 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0105 article-title: Exercise prevents Western diet-associated erectile dysfunction and coronary artery endothelial dysfunction: response to acute apocynin and sepiapterin treatment publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. doi: 10.1152/ajpregu.00049.2013 – volume: 337 start-page: 115 year: 1997 ident: 10.1016/j.ymeth.2016.07.012_b0050 article-title: Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production publication-title: Arch. Biochem. Biophys. doi: 10.1006/abbi.1997.9766 – volume: 12 start-page: 142 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0075 article-title: Hyperglycemia induces differential change in oxidative stress at gene expression and functional levels in HUVEC and HMVEC publication-title: Cardiovasc. Diabetol. doi: 10.1186/1475-2840-12-142 – volume: 292 start-page: R764 year: 2007 ident: 10.1016/j.ymeth.2016.07.012_b0090 article-title: Sexual dimorphism in oxidant status in spontaneously hypertensive rats publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. doi: 10.1152/ajpregu.00322.2006 – volume: 21 start-page: 983 year: 2000 ident: 10.1016/j.ymeth.2016.07.012_b0165 article-title: Dietary choline restriction causes complex I dysfunction and increased H2O2 generation in liver mitochondria publication-title: Carcinogenesis doi: 10.1093/carcin/21.5.983 – volume: 34 start-page: 3305 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0175 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.00677-14 – volume: 9 start-page: 515 year: 1990 ident: 10.1016/j.ymeth.2016.07.012_b0020 article-title: Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury publication-title: Free Radical Biol. Med. doi: 10.1016/0891-5849(90)90131-2 – volume: 11 start-page: 424 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0125 article-title: Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis publication-title: J. Sex. Med. doi: 10.1111/jsm.12391 – volume: 38 start-page: 259 year: 2004 ident: 10.1016/j.ymeth.2016.07.012_b0040 article-title: Detection of superoxide and peroxynitrite in model systems and mitochondria by the luminol analogue L-012 publication-title: Free Radical Res. doi: 10.1080/10715760410001659773 – volume: 47 start-page: 1371 year: 2009 ident: 10.1016/j.ymeth.2016.07.012_b0230 article-title: Blood reflects tissue oxidative stress depending on biomarker and tissue studies publication-title: Free Radical Biol. Med. doi: 10.1016/j.freeradbiomed.2009.07.014 – volume: 10 start-page: e0140728 year: 2015 ident: 10.1016/j.ymeth.2016.07.012_b0120 article-title: Chronic cigarette smoking impairs erectile function through increased oxidative stress and apoptosis, decreased nNOS, endothelial and smooth muscle contents in a rat model publication-title: PLoS ONE doi: 10.1371/journal.pone.0140728 – volume: 373 start-page: 447 year: 2000 ident: 10.1016/j.ymeth.2016.07.012_b0055 article-title: Lucigenin: redox potential in aqueous media and redox cycling with O−2 production publication-title: Arch. Biochem. Biophys. doi: 10.1006/abbi.1999.1579 – volume: 10 start-page: 694 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0110 article-title: Erectile dysfunction precedes coronary artery endothelial dysfunction in rats fed a high-fat, high-sucrose, Western pattern diet publication-title: J. Sex. Med. doi: 10.1111/jsm.12001 – volume: 294 start-page: E345 year: 2008 ident: 10.1016/j.ymeth.2016.07.012_b0145 article-title: Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kB activation via NADPH oxidase publication-title: Am. J. Physiol. Endocrinol. Metab. doi: 10.1152/ajpendo.00456.2007 – volume: 51 start-page: 153 year: 2011 ident: 10.1016/j.ymeth.2016.07.012_b0205 article-title: Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red publication-title: Free Radical Biol. Med. doi: 10.1016/j.freeradbiomed.2011.03.016 – volume: 125 start-page: 981 year: 2015 ident: 10.1016/j.ymeth.2016.07.012_b0160 article-title: Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease publication-title: J. Clin. Invest. doi: 10.1172/JCI73957 – volume: 90 start-page: 140 year: 2011 ident: 10.1016/j.ymeth.2016.07.012_b0080 article-title: Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner publication-title: Cardiovasc. Res. doi: 10.1093/cvr/cvq355 – volume: 22 start-page: 141 year: 1989 ident: 10.1016/j.ymeth.2016.07.012_b0190 article-title: Intracerebral microdialysis: I. experimental studies of diffusion kinetics publication-title: J. Pharmacol. Methods doi: 10.1016/0160-5402(89)90011-9 – volume: 3 start-page: 17 year: 2011 ident: 10.1016/j.ymeth.2016.07.012_b0250 article-title: Biochemical study of oxidative stress markers in the liver, kidney and heart of high fat diet induced obesity in rats publication-title: Diabetol. Metab. Syndr. doi: 10.1186/1758-5996-3-17 – volume: 402 start-page: 2233 year: 2012 ident: 10.1016/j.ymeth.2016.07.012_b0025 article-title: Application of medical and analytical methods in Lyme borreliosis monitoring publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-011-5451-z – volume: 296 start-page: H220 year: 2009 ident: 10.1016/j.ymeth.2016.07.012_b0085 article-title: NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2 publication-title: Am. J. Physiol. Heart Circ. Physiol. doi: 10.1152/ajpheart.00987.2008 – volume: 63 start-page: 387 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0195 article-title: Novel method for detection of reactive oxygen species in vivo in human skeletal muscle publication-title: Physiol. Res. doi: 10.33549/physiolres.932587 – volume: 11 start-page: 2661 year: 2014 ident: 10.1016/j.ymeth.2016.07.012_b0115 article-title: Prolonged therapy with the soluble guanylyl cyclase activator BAY 60–2770 restores the erectile function in obese mice publication-title: J. Sex. Med. doi: 10.1111/jsm.12682 – volume: 114 start-page: 1752 year: 2004 ident: 10.1016/j.ymeth.2016.07.012_b0140 article-title: Increased oxidative stress in obesity and its impact on metabolic syndrome publication-title: J. Clin. Invest. doi: 10.1172/JCI21625 – volume: 36 start-page: 270 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0235 article-title: Sulfur mustard causes oxidative stress and depletion of antioxidants in muscles, livers, and kidneys of Wistar rats publication-title: Drug Chem. Toxicol. doi: 10.3109/01480545.2012.710629 – volume: 380 start-page: 50 year: 2007 ident: 10.1016/j.ymeth.2016.07.012_b0030 article-title: Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking publication-title: Clin. Chim. Acta doi: 10.1016/j.cca.2007.01.028 – volume: 591 start-page: 3471 year: 2013 ident: 10.1016/j.ymeth.2016.07.012_b0100 article-title: Novel role for thioredoxin reductase-2 in mitochondrial redox adaptations to obesogenic diet and exercise in heart and skeletal muscle publication-title: J. Physiol. doi: 10.1113/jphysiol.2013.254193 – volume: 11 start-page: 81 year: 1991 ident: 10.1016/j.ymeth.2016.07.012_b0260 article-title: Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes publication-title: Free Radical Biol. Med. doi: 10.1016/0891-5849(91)90192-6 – volume: 202 start-page: 133 year: 1997 ident: 10.1016/j.ymeth.2016.07.012_b0065 article-title: A highly sensitive fluorescent micro-assay of H2O2 release from activated human leukocytes using a dihydroxyphenoxazine derivative publication-title: J. Immunol. Methods doi: 10.1016/S0022-1759(96)00244-X – volume: 4 start-page: N270 year: 1979 ident: 10.1016/j.ymeth.2016.07.012_b0015 article-title: The discovery of the superoxide radical publication-title: Trends Biochem. Sci. doi: 10.1016/0968-0004(79)90203-2 – volume: 11 start-page: 1041 year: 2004 ident: 10.1016/j.ymeth.2016.07.012_b0240 article-title: Vitamin C: basic metabolism and its function as an index of oxidative stress publication-title: Curr. Med. Chem. doi: 10.2174/0929867043455567 – volume: 253 start-page: 162 year: 1997 ident: 10.1016/j.ymeth.2016.07.012_b0070 article-title: A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases publication-title: Anal. Biochem. doi: 10.1006/abio.1997.2391 – volume: 111 start-page: 20 year: 2011 ident: 10.1016/j.ymeth.2016.07.012_b0275 article-title: Reactive oxygen species (ROS) from NADPH and xanthine oxidase modulate the cutaneous local heating response in healthy humans publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.01448.2010 – volume: 119 start-page: 573 year: 2009 ident: 10.1016/j.ymeth.2016.07.012_b0095 article-title: Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans publication-title: J. Clin. Invest. doi: 10.1172/JCI37048 – volume: 95 start-page: 323 year: 2016 ident: 10.1016/j.ymeth.2016.07.012_b0280 article-title: Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies publication-title: Free Radical Biol. Med. doi: 10.1016/j.freeradbiomed.2016.03.027 – volume: 52 start-page: 1648 year: 2012 ident: 10.1016/j.ymeth.2016.07.012_b0135 article-title: Green tea catechins ameliorate adipose insulin resistance by improving oxidative stress publication-title: Free Radical Biol. Med. doi: 10.1016/j.freeradbiomed.2012.01.033 – reference: 20370560 - Free Radic Res. 2010 Jun;44(6):587-604 – reference: 23170997 - J Sex Med. 2013 Mar;10 (3):694-703 – reference: 1738000 - J Neurochem. 1992 Mar;58(3):931-40 – reference: 24958099 - Mol Cell Biol. 2014 Sep;34(17):3305-20 – reference: 19188683 - J Clin Invest. 2009 Mar;119(3):573-81 – reference: 1937131 - Free Radic Biol Med. 1991;11(1):81-128 – reference: 9367498 - Anal Biochem. 1997 Nov 15;253(2):162-8 – reference: 10620371 - Arch Biochem Biophys. 2000 Jan 15;373(2):447-50 – reference: 23384123 - Clin Sci (Lond). 2013 Jul 1;125(2):87-97 – reference: 27021961 - Free Radic Biol Med. 2016 Jun;95:323-32 – reference: 23761637 - Am J Physiol Regul Integr Comp Physiol. 2013 Aug 15;305(4):R423-34 – reference: 14597645 - Hypertension. 2003 Dec;42(6):1150-6 – reference: 26491965 - PLoS One. 2015 Oct 22;10(10):e0140728 – reference: 5389100 - J Biol Chem. 1969 Nov 25;244(22):6049-55 – reference: 26713567 - Physiol Res. 2015 ;64(6):849-56 – reference: 21071431 - Cardiovasc Res. 2011 Apr 1;90(1):140-7 – reference: 18205546 - Antioxid Redox Signal. 2008 May;10(5):963-72 – reference: 24251665 - J Sex Med. 2014 Feb;11(2):424-30 – reference: 25621497 - J Clin Invest. 2015 Mar 2;125(3):981-92 – reference: 7915779 - Lancet. 1994 Sep 10;344(8924):721-4 – reference: 24951753 - Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H524-32 – reference: 9107302 - J Immunol Methods. 1997 Mar 28;202(2):133-41 – reference: 15078165 - Curr Med Chem. 2004 Apr;11(8):1041-64 – reference: 1639354 - Hepatology. 1992 Aug;16(2):448-53 – reference: 22015476 - Anal Bioanal Chem. 2012 Mar;402(7):2233-48 – reference: 25631019 - Methods Mol Biol. 2015;1264:245-61 – reference: 24093550 - Cardiovasc Diabetol. 2013 Oct 05;12 :142 – reference: 21783758 - Environ Toxicol Pharmacol. 2007 Mar;23(2):198-204 – reference: 2079232 - Free Radic Biol Med. 1990;9(6):515-40 – reference: 15129734 - Free Radic Res. 2004 Mar;38(3):259-69 – reference: 16917021 - Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R764-8 – reference: 19028794 - Am J Physiol Heart Circ Physiol. 2009 Jan;296(1):H220-5 – reference: 22978713 - Antioxid Redox Signal. 2014 Jan 10;20(2):372-82 – reference: 8225026 - Free Radic Biol Med. 1993 Oct;15(4):447-51 – reference: 23613536 - J Physiol. 2013 Jul 15;591(14):3471-86 – reference: 22330066 - Free Radic Biol Med. 2012 May 1;52(9):1648-57 – reference: 11230333 - Hypertension. 2001 Feb;37(2 Pt 2):547-53 – reference: 17336279 - Clin Chim Acta. 2007 May 1;380(1-2):50-8 – reference: 22139901 - J Biol Chem. 2012 Jan 27;287(5):2984-95 – reference: 21436462 - J Appl Physiol (1985). 2011 Jul;111(1):20-6 – reference: 19265063 - J Appl Physiol (1985). 2009 May;106(5):1529-37 – reference: 21812977 - Diabetol Metab Syndr. 2011 Aug 03;3(1):17 – reference: 2586112 - J Pharmacol Methods. 1989 Nov;22(3):157-83 – reference: 18073321 - Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E345-51 – reference: 11124139 - Am J Physiol Regul Integr Comp Physiol. 2001 Jan;280(1):R100-7 – reference: 8187280 - Circ Res. 1994 Jun;74(6):1141-8 – reference: 22947058 - Drug Chem Toxicol. 2013 Jul;36(3):270-6 – reference: 24564604 - Physiol Res. 2014;63(3):387-92 – reference: 10783322 - Carcinogenesis. 2000 May;21(5):983-9 – reference: 26577176 - Free Radic Biol Med. 2016 Jan;90:173-83 – reference: 15599400 - J Clin Invest. 2004 Dec;114(12):1752-61 – reference: 25196910 - J Sex Med. 2014 Nov;11(11):2661-70 – reference: 2586111 - J Pharmacol Methods. 1989 Nov;22(3):141-56 – reference: 17296874 - Hypertension. 2007 Apr;49(4):717-27 – reference: 13332224 - J Gerontol. 1956 Jul;11(3):298-300 – reference: 19616614 - Free Radic Biol Med. 2009 Nov 15;47(10):1371-4 – reference: 21419845 - Free Radic Biol Med. 2011 Jul 1;51(1):153-9 – reference: 8990275 - Arch Biochem Biophys. 1997 Jan 1;337(1):115-20 |
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| SubjectTerms | adipose tissue Amplex Red Animals byproducts H2O2 hydrogen peroxide Hydrogen Peroxide - chemistry Hydrogen Peroxide - isolation & purification kidneys Liver Mice microdialysis Microdialysis - methods Muscle, Skeletal - chemistry Muscle, Skeletal - metabolism Oxidative Stress pathogenesis penis Rats Reactive Oxygen Species - chemistry Reactive Oxygen Species - isolation & purification Redox Rodentia ROS detection skeletal muscle Superoxides - chemistry Superoxides - isolation & purification |
| Title | A microdialysis method to measure in vivo hydrogen peroxide and superoxide in various rodent tissues |
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