ImputAccur: fast and user-friendly calculation of genotype-imputation accuracy-measures

Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamen...

Full description

Saved in:
Bibliographic Details
Published inBMC bioinformatics Vol. 23; no. 1; pp. 316 - 6
Main Authors Thormann, Kolja A., Tozzi, Viola, Starke, Paula, Bickeböller, Heike, Baum, Marcus, Rosenberger, Albert
Format Journal Article
LanguageEnglish
Published London BioMed Central 04.08.2022
Springer Nature B.V
BMC
Subjects
Accuracy
Algorithms
Bioinformatics
Biomedical and Life Sciences
Chromosomes
Classification
Computational Biology/Bioinformatics
Computer Appl. in Life Sciences
Data analysis
Filtration
Genome-wide association studies
Genome-Wide Association Study
Genomes
Genotype
Genotype & phenotype
Genotypes
GWAS
Imputation
Life Sciences
Marker selection
Markers
Microarrays
Names
Polymorphism, Single Nucleotide
Quality control
SNP
Software
Source code
Marker selection
Accuracy
Imputation
GWAS
SNP
Quality control
Online AccessGet full text
ISSN1471-2105
1471-2105
DOI10.1186/s12859-022-04863-z

Cover

Abstract Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical. Results With ImputAccur, the accuracy measures info, Iam-hiQ and r 2 -based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis. Conclusions The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .
AbstractList Abstract Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical. Results With ImputAccur, the accuracy measures info, Iam-hiQ and r 2 -based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis. Conclusions The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .
Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical. Results With ImputAccur, the accuracy measures info, Iam-hiQ and r 2 -based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis. Conclusions The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .
ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical. With ImputAccur, the accuracy measures info, Iam-hiQ and r -based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis. The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .
ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical.BACKGROUNDImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical.With ImputAccur, the accuracy measures info, Iam-hiQ and r2-based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis.RESULTSWith ImputAccur, the accuracy measures info, Iam-hiQ and r2-based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis.The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .CONCLUSIONSThe source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git .
Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy for imputed genotypes is fundamental. Several accuracy measures have been proposed, but unfortunately, they are implemented on different platforms, which is impractical. Results With ImputAccur, the accuracy measures info, Iam-hiQ and r2-based indices can be derived from standard output files of imputation software. Sample/probe and marker filtering is possible. This allows e.g. accurate marker filtering ahead of data analysis. Conclusions The source code (Python version 3.9.4), a standalone executive file, and example data for ImputAccur are freely available at https://gitlab.gwdg.de/kolja.thormann1/imputationquality.git.
ArticleNumber 316
Author Starke, Paula
Rosenberger, Albert
Tozzi, Viola
Baum, Marcus
Thormann, Kolja A.
Bickeböller, Heike
Author_xml – sequence: 1
  givenname: Kolja A.
  surname: Thormann
  fullname: Thormann, Kolja A.
  email: koljaalexander.thormann@uni-goettingen.de
  organization: Institute of Computer Science, Georg-August-University Göttingen
– sequence: 2
  givenname: Viola
  surname: Tozzi
  fullname: Tozzi, Viola
  organization: Department of Genetic Epidemiology, University Medical Center Göttingen
– sequence: 3
  givenname: Paula
  surname: Starke
  fullname: Starke, Paula
  organization: Department of Genetic Epidemiology, University Medical Center Göttingen
– sequence: 4
  givenname: Heike
  surname: Bickeböller
  fullname: Bickeböller, Heike
  organization: Department of Genetic Epidemiology, University Medical Center Göttingen
– sequence: 5
  givenname: Marcus
  surname: Baum
  fullname: Baum, Marcus
  organization: Institute of Computer Science, Georg-August-University Göttingen
– sequence: 6
  givenname: Albert
  orcidid: 0000-0001-7848-1332
  surname: Rosenberger
  fullname: Rosenberger, Albert
  email: arosenb@gwdg.de
  organization: Department of Genetic Epidemiology, University Medical Center Göttingen
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35927623$$D View this record in MEDLINE/PubMed
BookMark eNqNkUtv1TAQhSNURB_wB1igSGzYBOyJX2GBVFUFrlSJDYil5TiTS64SO9hJUfrr69tcSssCsbI9PufzzPFpduS8wyx7SclbSpV4FykoXhUEoCBMibK4eZKdUCZpAZTwowf74-w0xh0hVCrCn2XHJa9ACihPsu-bYZync2vn8D5vTZxy45p8jhiKNnTomn7Jrent3Jup8y73bb5F56dlxKLbW9ey2QOMXYoBTZwDxufZ09b0EV8c1rPs28fLrxefi6svnzYX51eFZRWdCqxroQQTWIuaM1ZyKmktjWxRoVJMcQBJBYAtK5suBIrkKxlXhFED1pRn2WblNt7s9Bi6wYRFe9Ppu4IPW23C1NketYW6sVUCNIqxRkIteNlaSQRwqNMpscqVNbvRLL9M398DKdH7yPUauU6R67vI9U1yfVhd41wP2Fh0UzD9o1Ye37juh976a12laQGqBHhzAAT_c8Y46aGLFvveOPRz1CCqSpISgCXp67-kOz8HlwLWkCRScFaRpHr1sKP7Vn7_ehLAKrDBxxiw_b85D-nEJHZbDH_e_ofrFrOvz8A
Cites_doi 10.1038/nprot.2014.071
10.1038/ejhg.2017.51
10.1016/j.ajhg.2009.01.005
10.1186/1755-8794-5-12
10.1038/nrg2796
10.1186/s12859-022-04568-3
10.1007/978-1-62703-447-0_17
10.1146/annurev-genom-083117-021602
ContentType Journal Article
Copyright The Author(s) 2022
2022. The Author(s).
2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2022
– notice: 2022. The Author(s).
– notice: 2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7QO
7SC
7X7
7XB
88E
8AL
8AO
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABUWG
AEUYN
AFKRA
ARAPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
HCIFZ
JQ2
K7-
K9.
L7M
LK8
L~C
L~D
M0N
M0S
M1P
M7P
P5Z
P62
P64
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
Q9U
7X8
5PM
ADTOC
UNPAY
DOA
DOI 10.1186/s12859-022-04863-z
DatabaseName Springer Nature OA Free Journals
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Biotechnology Research Abstracts
Computer and Information Systems Abstracts
ProQuest Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Computing Database (Alumni Edition)
ProQuest Pharma Collection
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Journals
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central
ProQuest Advanced Technologies & Aerospace Database
ProQuest Central Essentials Local Electronic Collection Information
Biological Science Collection
ProQuest Central
ProQuest Technology Collection
Natural Science Collection
ProQuest One Community College
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
ProQuest SciTech Premium Collection
ProQuest Computer Science Collection
ProQuest Computer Science Database
ProQuest Health & Medical Complete (Alumni)
Advanced Technologies Database with Aerospace
Biological Sciences
Computer and Information Systems Abstracts – Academic
Computer and Information Systems Abstracts Professional
Computing Database
Health & Medical Collection (Alumni Edition)
Medical Database
ProQuest Biological Science Database
Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest Central Basic
MEDLINE - Academic
PubMed Central (Full Participant titles)
Unpaywall for CDI: Periodical Content
Unpaywall
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
Computer Science Database
ProQuest Central Student
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
ProQuest Computer Science Collection
Computer and Information Systems Abstracts
SciTech Premium Collection
ProQuest Central China
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
Health Research Premium Collection
Natural Science Collection
Health & Medical Research Collection
Biological Science Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
Advanced Technologies & Aerospace Collection
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Engineering Research Database
ProQuest One Academic
ProQuest One Academic (New)
Technology Collection
Technology Research Database
Computer and Information Systems Abstracts – Academic
ProQuest One Academic Middle East (New)
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
ProQuest Health & Medical Research Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Advanced Technologies Database with Aerospace
ProQuest Computing
ProQuest Central Basic
ProQuest Computing (Alumni Edition)
ProQuest SciTech Collection
Computer and Information Systems Abstracts Professional
Advanced Technologies & Aerospace Database
ProQuest Medical Library
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList

MEDLINE
MEDLINE - Academic
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: C6C
  name: Springer Nature OA Free Journals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 3
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 4
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 5
  dbid: UNPAY
  name: Unpaywall
  url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/
  sourceTypes: Open Access Repository
– sequence: 6
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1471-2105
EndPage 6
ExternalDocumentID oai_doaj_org_article_c2bdc96c4d844d72b653fc706252b2b6
10.1186/s12859-022-04863-z
PMC9351229
35927623
10_1186_s12859_022_04863_z
Genre Journal Article
GrantInformation_xml – fundername: National Institutes of Health (7U19CA203654-02/ 397 114564-5111078 Integrative Analysis of Lung Cancer Etiology and Risk).
– fundername: Georg-August-Universität Göttingen (1018)
– fundername: NCI NIH HHS
  grantid: U19 CA203654
– fundername: ;
GroupedDBID ---
0R~
23N
2WC
53G
5VS
6J9
7X7
88E
8AO
8FE
8FG
8FH
8FI
8FJ
AAFWJ
AAJSJ
AAKPC
AASML
ABDBF
ABUWG
ACGFO
ACGFS
ACIHN
ACIWK
ACPRK
ACUHS
ADBBV
ADMLS
ADUKV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AFRAH
AHBYD
AHMBA
AHYZX
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMTXH
AOIJS
ARAPS
AZQEC
BAPOH
BAWUL
BBNVY
BCNDV
BENPR
BFQNJ
BGLVJ
BHPHI
BMC
BPHCQ
BVXVI
C6C
CCPQU
CS3
DIK
DU5
DWQXO
E3Z
EAD
EAP
EAS
EBD
EBLON
EBS
EMB
EMK
EMOBN
ESX
F5P
FYUFA
GNUQQ
GROUPED_DOAJ
GX1
HCIFZ
HMCUK
HYE
IAO
ICD
IHR
INH
INR
ISR
ITC
K6V
K7-
KQ8
LK8
M1P
M48
M7P
MK~
ML0
M~E
O5R
O5S
OK1
OVT
P2P
P62
PGMZT
PHGZM
PHGZT
PIMPY
PJZUB
PPXIY
PQGLB
PQQKQ
PROAC
PSQYO
PUEGO
RBZ
RNS
ROL
RPM
RSV
SBL
SOJ
SV3
TR2
TUS
UKHRP
W2D
WOQ
WOW
XH6
XSB
AAYXX
CITATION
ALIPV
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7QO
7SC
7XB
8AL
8FD
8FK
FR3
JQ2
K9.
L7M
L~C
L~D
M0N
P64
PKEHL
PQEST
PQUKI
PRINS
Q9U
7X8
5PM
123
2VQ
4.4
ADRAZ
ADTOC
AHSBF
C1A
EJD
H13
IPNFZ
RIG
UNPAY
ID FETCH-LOGICAL-c491t-ebb68646eb6b54435171b7a7fe8e884852271622c39c1b76e6c493458041a2ca3
IEDL.DBID M48
ISSN 1471-2105
IngestDate Fri Oct 03 12:49:08 EDT 2025
Sun Oct 26 02:20:32 EDT 2025
Tue Sep 30 16:24:26 EDT 2025
Thu Oct 02 11:29:02 EDT 2025
Tue Oct 07 05:31:43 EDT 2025
Mon Jul 21 05:46:02 EDT 2025
Wed Oct 01 04:15:39 EDT 2025
Sat Sep 06 07:27:24 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Marker selection
Accuracy
Imputation
GWAS
SNP
Quality control
Language English
License 2022. The Author(s).
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
cc-by
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c491t-ebb68646eb6b54435171b7a7fe8e884852271622c39c1b76e6c493458041a2ca3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ORCID 0000-0001-7848-1332
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1186/s12859-022-04863-z
PMID 35927623
PQID 2703765490
PQPubID 44065
PageCount 6
ParticipantIDs doaj_primary_oai_doaj_org_article_c2bdc96c4d844d72b653fc706252b2b6
unpaywall_primary_10_1186_s12859_022_04863_z
pubmedcentral_primary_oai_pubmedcentral_nih_gov_9351229
proquest_miscellaneous_2699703224
proquest_journals_2703765490
pubmed_primary_35927623
crossref_primary_10_1186_s12859_022_04863_z
springer_journals_10_1186_s12859_022_04863_z
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2022-08-04
PublicationDateYYYYMMDD 2022-08-04
PublicationDate_xml – month: 08
  year: 2022
  text: 2022-08-04
  day: 04
PublicationDecade 2020
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle BMC bioinformatics
PublicationTitleAbbrev BMC Bioinformatics
PublicationTitleAlternate BMC Bioinformatics
PublicationYear 2022
Publisher BioMed Central
Springer Nature B.V
BMC
Publisher_xml – name: BioMed Central
– name: Springer Nature B.V
– name: BMC
References TW Winkler (4863_CR4) 2014; 9
M Mitt (4863_CR7) 2017; 25
S Krithika (4863_CR8) 2012; 5
JM Hickey (4863_CR1) 2013; 1019
A Rosenberger (4863_CR6) 2022; 23
BL Browning (4863_CR5) 2009; 84
S Das (4863_CR2) 2018; 31
J Marchini (4863_CR3) 2010; 11
References_xml – volume: 9
  start-page: 1192
  issue: 5
  year: 2014
  ident: 4863_CR4
  publication-title: Nat Protoc
  doi: 10.1038/nprot.2014.071
– volume: 25
  start-page: 869
  issue: 7
  year: 2017
  ident: 4863_CR7
  publication-title: Eur J Hum Genet
  doi: 10.1038/ejhg.2017.51
– volume: 84
  start-page: 210
  issue: 2
  year: 2009
  ident: 4863_CR5
  publication-title: Am J Hum Genet
  doi: 10.1016/j.ajhg.2009.01.005
– volume: 5
  start-page: 12
  year: 2012
  ident: 4863_CR8
  publication-title: BMC Med Genom
  doi: 10.1186/1755-8794-5-12
– volume: 11
  start-page: 499
  issue: 7
  year: 2010
  ident: 4863_CR3
  publication-title: Nat Rev Genet
  doi: 10.1038/nrg2796
– volume: 23
  start-page: 50
  issue: 1
  year: 2022
  ident: 4863_CR6
  publication-title: BMC Bioinform
  doi: 10.1186/s12859-022-04568-3
– volume: 1019
  start-page: 395
  year: 2013
  ident: 4863_CR1
  publication-title: Methods Mol Biol
  doi: 10.1007/978-1-62703-447-0_17
– volume: 31
  start-page: 73
  issue: 19
  year: 2018
  ident: 4863_CR2
  publication-title: Annu Rev Genom Hum Genet
  doi: 10.1146/annurev-genom-083117-021602
SSID ssj0017805
Score 2.3967323
Snippet Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide...
ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide association studies...
Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide...
Abstract Background ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide...
SourceID doaj
unpaywall
pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 316
SubjectTerms Accuracy
Algorithms
Bioinformatics
Biomedical and Life Sciences
Chromosomes
Classification
Computational Biology/Bioinformatics
Computer Appl. in Life Sciences
Data analysis
Filtration
Genome-wide association studies
Genome-Wide Association Study
Genomes
Genotype
Genotype & phenotype
Genotypes
GWAS
Imputation
Life Sciences
Marker selection
Markers
Microarrays
Names
Polymorphism, Single Nucleotide
Quality control
SNP
Software
Source code
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwEB6hSgg4IN6kFBQkbtTqxnb84FYQVUGCExW9WbbjiEpLturuCm1_fWfiJHQFAg4cYzuRM5_HM-PHNwCv6roVNdo5FngbmUxWsIBmkiWhdct5o3RLF4U_fVbHJ_LjaX16LdUXnQnL9MBZcAeRhyZaFWVjpGw0D6oWbdQz9Nt5wCeafWfGjsHUsH9ATP3jFRmjDpYV8bQxOrlOFHOCXW6ZoZ6t_3cu5q8nJaft0jtwa92d-80PP59fs0hH9-Du4EqWh_kX7sON1D2Amzm55OYhfP1A-RoOY1xfvClbv1yVvmtKWpRgLZEbN_NNiQDFIX9XuWhLImylNVl2Rq_mYk8f8HHDvufVxOUjODl6_-XdMRvSKLAobbViKQRllFQpqEBsd3Wlq6A9gmCSMdKgB0Y0UjwKG7FCJRS2FbImZiLPoxePYadbdOkpXfBOilpLKyvZRB2a0GKEKLxS0ibjC3g9StWdZ7YM10cZRrmMgUMMXI-BuyzgLQl-aklM130B4u8G_N3f8C9gb4TNDeq3dBznMa0w9J0V8HKqRsWh3RDfpcUa2yhrsRm6MAU8yShPPRG15WglRAF6C_-trm7XdGffenJui_Ll3BawP46Un936kyj2p9H0D5Lb_R-Sewa3ea8RBpViD3ZWF-v0HD2sVXjRK9MVK0whXg
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3raxQxEB_qFVE_iG9Xq6zgNxvaTbLZRBBppaUKHiIW-23Ja7Vw7p33QK5_vTP7qodS_LjJZMnOY2cmj98AvMzzSuTo55jjlWcyGsEcukkWRVFUnAdVVHRR-ONYnZzKD2f52RaM-7swdKyy_yc2P-ow9bRGvsdRNQuF2cz-29lPRlWjaHe1L6Fhu9IK4U0DMXYNtjkhY41g-_Bo_OnzsK9ACP791Rmt9hYZ4bcxOtFO0HOCXWy4pwbF_1-h598nKIdt1FtwY1XP7PqXnUz-8FTHd-B2F2KmB61O3IWtWN-D623RyfV9-Pqe6jgceL-av04ru1imtg4pLVawikCPw2SdouB8V9crnVYpAbnSWi07p6Fts6UXWL9mP9pVxsUDOD0--vLuhHXlFZiXJluy6JzSSqrolCMUvDwrMldYFI6OWkuNkRnBS3EvjMcOFRWOEzInxCLLvRUPYVRP6_iYLn5HRdTSyEwGX7jgKswchVVKmqhtAq96rpazFkWjbLIPrcpWBiXKoGxkUF4kcEiMHygJAbtpmM6_lZ1BlZ674A1OKWgpQ8GdykXli33M57jDpwR2erGVnVkuykslSuDF0I0GRbskto7TFdIoY5AMQ5sEHrVSHmYicsPRe4gEig35b0x1s6c-_96AdhvkL-cmgd1eUy6ndRUrdgdt-g_OPbn6o5_CTd7oukZ134HRcr6KzzCmWrrnnaH8BjVNH00
  priority: 102
  providerName: ProQuest
– databaseName: Springer Nature OA Free Journals
  dbid: C6C
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3daxQxEB-0ItYH8burVVbwzQa7STYffavFUgV9sti3kGQTLJx7pXdHuf71ndnd2_awiD5uvgjzy-xMMslvAN7XdRY12jkWeI5MJitYQDPJktA6c94onemh8Lfv6uhYfj2pTwaaHHoLczN-Xxn1cVYRwxqjO-dEDifY5V24h0ZKdYFZdTBGDIibf_Uo5tZ-a4an4-e_zan8827kGCB9CA8W7ZlfXvjJ5IYNOnwMjwbnsdzv0X4Cd1L7FO736SSXz-DnF8rQsB_j4nyvzH42L33blHQMwTLRGTeTZYmQxCFjVznNJVG00iksO6WufbGnAXxcst_9-eHsORwffv5xcMSGxAksSlvNWQpBGSVVCioQv11d6Spoj2I3yRhp0Oci4igehY1YoZLCfkLWxEXkefTiBWy00zZt0ZPupKi1tLKSTdShCRn3hMIrJW0yvoAPK6m6s54fw3X7CqNcj4FDDFyHgbss4BMJfmxJ3NZdAULuBlVxkYcmWpxSY6RsNA-qFjnqXdyp8YBfBWyvYHODws0cxz-XVrjZ3S3g3ViNqkLxD9-m6QLbKGuxGTotBbzsUR5nImrL0S6IAvQa_mtTXa9pT391dNwW5cu5LWBntVKup_U3UeyMq-kfJPfq_0Z_DZu8W_sGl_82bMzPF-kNek_z8LZTmyuvqhI5
  priority: 102
  providerName: Springer Nature
– databaseName: Unpaywall
  dbid: UNPAY
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwED-NTgh44PsjMFCQeGPuFtuxY94KYhpITAhRMZ4i23Ggokurfgi1fz13-SgrTAgkHhOfI-fyc-7O9v0O4FmaliJFO8ccLz2TwQjm0EyyILQuOS-ULilR-N2JOh7Kt6fp6Q586HJh3Jl3o0lLGkpExf3zaejjJsuBqiiE2cG0KJtJn6mDeUJMbIzOphOJnGDrS7CrUvTPe7A7PHk_-FynGemEYYyTdtkzF3bcslA1kf9F3ufvhyg3O6nX4MqymtrVdzsenzNWRzdg3r1mc0blW3-5cH2__oUB8v_q4SZcb33beNCA8RbshOo2XG6qXa7uwKc3VEBi4P1y9iIu7XwR26qIaZWElcS2XIxXMSLGtwXF4kkZE4MsLRKzEXVtblt6gPUrdtYsb87vwvDo9cdXx6yt68C8NMmCBedUpqQKTjmi30sTnThtERVZyDKZoUtIvFbcC-OxQQWF_YRMiSrJcm_FPehVkyo8oIzzoEhaGpnIwmtXuBJDVmGVkiZkNoLn3bfMpw19R16HPZnKG1XlqKq8VlW-juAlfe6NJFFv1zcmsy95O5Nzz13hDQ6pyKQsNHcqFaXXhxhIcodXEex1YMnb_8E85_hj1Qpj8cMInm6acSbT9oytwmSJMsoYFEOfKoL7DbY2IxGp4Wi2RAR6C3VbQ91uqUZfa7Zwg_rl3ESw3-Hz57D-pIr9DYb_QnMP_038EVzlNUQzROke9BazZXiMzt3CPWln6w8hiUsE
  priority: 102
  providerName: Unpaywall
Title ImputAccur: fast and user-friendly calculation of genotype-imputation accuracy-measures
URI https://link.springer.com/article/10.1186/s12859-022-04863-z
https://www.ncbi.nlm.nih.gov/pubmed/35927623
https://www.proquest.com/docview/2703765490
https://www.proquest.com/docview/2699703224
https://pubmed.ncbi.nlm.nih.gov/PMC9351229
https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-022-04863-z
https://doaj.org/article/c2bdc96c4d844d72b653fc706252b2b6
UnpaywallVersion publishedVersion
Volume 23
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVADU
  databaseName: BioMed Central
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: RBZ
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://www.biomedcentral.com/search/
  providerName: BioMedCentral
– providerCode: PRVAFT
  databaseName: Open Access Digital Library
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: KQ8
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html
  providerName: Colorado Alliance of Research Libraries
– providerCode: PRVAFT
  databaseName: Open Access Digital Library
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: KQ8
  dateStart: 20000701
  isFulltext: true
  titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html
  providerName: Colorado Alliance of Research Libraries
– providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: DOA
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVEBS
  databaseName: EBSCOhost Academic Search Ultimate
  customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: ABDBF
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn
  providerName: EBSCOhost
– providerCode: PRVEBS
  databaseName: Inspec with Full Text
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: ADMLS
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://www.ebsco.com/products/research-databases/inspec-full-text
  providerName: EBSCOhost
– providerCode: PRVBFR
  databaseName: Free Medical Journals
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: DIK
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: http://www.freemedicaljournals.com
  providerName: Flying Publisher
– providerCode: PRVFQY
  databaseName: GFMER Free Medical Journals
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: GX1
  dateStart: 0
  isFulltext: true
  titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php
  providerName: Geneva Foundation for Medical Education and Research
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: M~E
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
– providerCode: PRVAQN
  databaseName: PubMed Central
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: RPM
  dateStart: 20000101
  isFulltext: true
  titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/
  providerName: National Library of Medicine
– providerCode: PRVPQU
  databaseName: Health Medical collection
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: 7X7
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central (subscription)
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: BENPR
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Technology Collection
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: 8FG
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/technologycollection1
  providerName: ProQuest
– providerCode: PRVFZP
  databaseName: Scholars Portal - Open Access
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 20250131
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: M48
  dateStart: 20000701
  isFulltext: true
  titleUrlDefault: http://journals.scholarsportal.info
  providerName: Scholars Portal
– providerCode: PRVAVX
  databaseName: Springer Nature HAS Fully OA
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: AAJSJ
  dateStart: 20001201
  isFulltext: true
  titleUrlDefault: https://www.springernature.com
  providerName: Springer Nature
– providerCode: PRVAVX
  databaseName: Springer Nature OA Free Journals
  customDbUrl:
  eissn: 1471-2105
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017805
  issn: 1471-2105
  databaseCode: C6C
  dateStart: 20000112
  isFulltext: true
  titleUrlDefault: http://www.springeropen.com/
  providerName: Springer Nature
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Zb9NAEB71EAIeEDeGEhmJN7pQ7673QEIojRpKpEYVEJE-WbvrNVQKTskhSH89s3acEhEheLHlvbSawzOzxzcAz9O0YCnaOWJp4Qj3mhGLZpJ4JmVBaS5kES4Kn_TF8YD3hulwC5p0R0sCTjeGdiGf1GAyevnz--ItKvybSuGVeDVNAgobCefSA4AcI5fbsIuWSodUDif8alch4PdXt41kQjDUSZtLNBvHWDNUFZ7_Jif0z7OUqw3Vm3B9Xl6YxQ8zGv1ms7q34dbS2YzbtXTcgS1f3oVrdfrJxT34_D5kdGg7N5-8jgszncWmzOOwbEGKAH-cjxYxstAtM3zF4yIOkK5h1Zach651sQkDGLcg3-r1xul9GHSPPnWOyTLRAnFcJzPirRVKcOGtsAEPL01kYqVBNimvFFfoowWgKeqYdlghvMB-jKcBu8hQZ9gD2CnHpX8UroB7EVpzzROeO2lzW2AMyYwQXHtlInjRUDW7qPE0sioOUSKreZAhD7KKB9llBIeB8KuWAQu7KhhPvmRL1coctbnTOKVccZ5LakXKCicPMLKjFr8i2GvYljXylVH800mBwfFBBM9W1ahaYb_ElH48xzZCa2yGTk4ED2sur2bCUk3RjrAI5Br_16a6XlOef63guzXSl1IdwX4jKVfT-hsp9lfS9A-Ue_xfdH4CN2gl-gqlfw92ZpO5f4rO1sy2YFsOJT5V910Ldtvt3scevg-P-qcfsLQjOq1qGaNVaRrWDPqn7bNfPh0qnA
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Zb9QwEB6VIlR4QNwECgQJnqjVxnacGAmhclS79HhqRd9c23Gg0pJd9lC1_VH8RmaSTcoKVPHSx9hONJnDM-PjG4BXaVqKFP0cc7z0TAYtmEM3yYLIspLzQmUlXRTeP1C9I_nlOD1egV_tXRg6VtnOifVEXQw9rZFvclTNTGE2s_V-9JNR1SjaXW1LaDRqsRvmZ5iyTd71P6F8X3O-8_nwY48tqgowL3UyZcE5lSupglOOwN_SJEtcZpGmPOS5zDEgIVQl7oX22KGCwveETAmox3JvBX73GlyXAucStJ_suEvwEqoP0F7MydXmJCF0OEbn5QnYTrDzJedX1wj4V2D79_nMbpP2FqzNqpGdn9nB4A8_uHMHbi8C2Hi70bi7sBKqe3CjKWk5vw9f-1QlYtv72fhtXNrJNLZVEdNSCCsJUrkYzGNUC7-oGhYPy5hgYmklmJ3Sq02zpQ9YP2c_mjXMyQM4uhI2P4TValiFx3StPCgaLbVMZOEzV7gS81JhlZI65DaCNy1XzajB6DB1bpMr08jAoAxMLQNzHsEHYnw3kvC164bh-JtZmKvx3BVeI0lFLmWRcadSUfpsC7NF7vApgvVWbGZh9BNzoaIRvOy60VxpD8ZWYTjDMUprHIaBUwSPGil3lIhUc_RNIoJsSf5LpC73VKffa0hwjfzlXEew0WrKBVmXsWKj06b_4NyTy3_6Baz1Dvf3zF7_YPcp3OS13ueo-uuwOh3PwjOM3qbueW0yMZxctY3-BhsIU54
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwELagiNcB8SZQIEjcqNXGdvzgVhZWLY-KAxW9WbZjQ6Ulu9rNCm1_PTNJNnRFheAYvzSa8WRmbM83hLwsy8RLsHPUsxSoiIZTD2aSRq5UYqySKmGi8KcjeXAs3p-UJ-ey-NvX7usryS6nAVGa6mZ3VqVOxbXcXRSIu0bxJTpCxnF6dplcEWDdsIbBSI6GewRE7F-nylw4b8Mctaj9F7maf76YHK5Nb5Lry3rmVj_dZHLOMo1vk1u9S5nvd3vgDrkU67vkaldkcnWPfD3Eug37ISznr_PkFk3u6irHwwmaEOS4mqxyEFTo63jl05QjcCuezdJTnNo1O1zAhRX90Z0qLu6T4_G7L6MD2pdToEGYoqHRe6mlkNFLj6h3ZaEKrxwIQ0ethQZPDOGkWOAmQIeMEuZxUSJCkWPB8Qdkq57W8REmekeJo4URhaiC8pVPEClyJ6UwUbuMvFpz1c461AzbRhta2k4GFmRgWxnYs4y8QcYPIxHxum2Yzr_ZXoFsYL4KBkiqtBCVYl6WPAW1B_Eb8_CVke212GyvhgvL4H-mJITAexl5MXSDAuGtiKvjdAljpDEwDFyZjDzspDxQwkvDwFrwjKgN-W-QutlTn35vQboN8Jcxk5Gd9U75TdbfWLEz7KZ_4Nzj_1v9Obn2-e3Yfjw8-vCE3GCtGmjQhG2y1cyX8Sm4V41_1mrQLx6IHW8
linkToUnpaywall http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwED-NTgh44PsjMFCQeGPuFtuxY94KYhpITAhRMZ4i23Ggokurfgi1fz13-SgrTAgkHhOfI-fyc-7O9v0O4FmaliJFO8ccLz2TwQjm0EyyILQuOS-ULilR-N2JOh7Kt6fp6Q586HJh3Jl3o0lLGkpExf3zaejjJsuBqiiE2cG0KJtJn6mDeUJMbIzOphOJnGDrS7CrUvTPe7A7PHk_-FynGemEYYyTdtkzF3bcslA1kf9F3ufvhyg3O6nX4MqymtrVdzsenzNWRzdg3r1mc0blW3-5cH2__oUB8v_q4SZcb33beNCA8RbshOo2XG6qXa7uwKc3VEBi4P1y9iIu7XwR26qIaZWElcS2XIxXMSLGtwXF4kkZE4MsLRKzEXVtblt6gPUrdtYsb87vwvDo9cdXx6yt68C8NMmCBedUpqQKTjmi30sTnThtERVZyDKZoUtIvFbcC-OxQQWF_YRMiSrJcm_FPehVkyo8oIzzoEhaGpnIwmtXuBJDVmGVkiZkNoLn3bfMpw19R16HPZnKG1XlqKq8VlW-juAlfe6NJFFv1zcmsy95O5Nzz13hDQ6pyKQsNHcqFaXXhxhIcodXEex1YMnb_8E85_hj1Qpj8cMInm6acSbT9oytwmSJMsoYFEOfKoL7DbY2IxGp4Wi2RAR6C3VbQ91uqUZfa7Zwg_rl3ESw3-Hz57D-pIr9DYb_QnMP_038EVzlNUQzROke9BazZXiMzt3CPWln6w8hiUsE
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=ImputAccur%3A+fast+and+user-friendly+calculation+of+genotype-imputation+accuracy-measures&rft.jtitle=BMC+bioinformatics&rft.au=Thormann%2C+Kolja+A.&rft.au=Tozzi%2C+Viola&rft.au=Starke%2C+Paula&rft.au=Bickeb%C3%B6ller%2C+Heike&rft.date=2022-08-04&rft.issn=1471-2105&rft.eissn=1471-2105&rft.volume=23&rft.issue=1&rft_id=info:doi/10.1186%2Fs12859-022-04863-z&rft.externalDBID=n%2Fa&rft.externalDocID=10_1186_s12859_022_04863_z
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1471-2105&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1471-2105&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1471-2105&client=summon