Tracking cortical entrainment in neural activity: auditory processes in human temporal cortex

• Published in: Frontiers in computational neuroscience Vol. 9; p. 5
• Main Authors: Thwaites, Andrew, Nimmo-Smith, Ian, Fonteneau, Elisabeth, Patterson, Roy D., Buttery, Paula, Marslen-Wilson, William D.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 10.02.2015; Frontiers Media S.A
• Subjects: Acoustics; Cognitive ability; Cortex (auditory); Cortex (somatosensory); Cortex (temporal); Entrainment; Fundamental frequency contour; Hypotheses; information encoding; Localization; Magnetoencephalography; MNE source space; Nervous system; neural computation; Neuroscience; NMR; Nuclear magnetic resonance; Speech; Speech envelope; Speech perception; Spread spectrum; Superior temporal sulcus; United Kingdom > UK; fundamental frequency contour; neural computation; model expression; speech envelope; MNE source space; magnetoencephalography; information encoding
• ISSN: 1662-5188; 1662-5188
• DOI: 10.3389/fncom.2015.00005

A primary objective for cognitive neuroscience is to identify how features of the sensory environment are encoded in neural activity. Current auditory models of loudness perception can be used to make detailed predictions about the neural activity of the cortex as an individual listens to speech. We used two such models (loudness-sones and loudness-phons), varying in their psychophysiological realism, to predict the instantaneous loudness contours produced by 480 isolated words. These two sets of 480 contours were used to search for electrophysiological evidence of loudness processing in whole-brain recordings of electro- and magneto-encephalographic (EMEG) activity, recorded while subjects listened to the words. The technique identified a bilateral sequence of loudness processes, predicted by the more realistic loudness-sones model, that begin in auditory cortex at ~80 ms and subsequently reappear, tracking progressively down the superior temporal sulcus (STS) at lags from 230 to 330 ms. The technique was then extended to search for regions sensitive to the fundamental frequency (F0) of the voiced parts of the speech. It identified a bilateral F0 process in auditory cortex at a lag of ~90 ms, which was not followed by activity in STS. The results suggest that loudness information is being used to guide the analysis of the speech stream as it proceeds beyond auditory cortex down STS toward the temporal pole.