A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension - Ferrer, Elisabet; Dunmore, Benjamin J.; Hassan, Dhiya; Ormiston, Mark L.; Moore, Stephen; Deighton, John; Long, Lu; Yang, Xu Dong; Stewart, Duncan J.; Morrell, Nicholas W. (American journal of respiratory cell and molecular biology, 2018)
Keywords: Animals; Apoptosis; Biomarkers; Biomarkers, Tumor - blood; Biomarkers, Tumor - metabolism; Bone morphogenetic protein receptor type II; Bone Morphogenetic Protein Receptors, Type II - genetics; Cell Movement; Cell Proliferation; Cell Shape; Colorectal cancer; Cytoskeleton; Disease Models, Animal; Endothelial cells; Endothelial Cells - metabolism; Endothelium; Exosomes; Exosomes - metabolism; Exosomes - ultrastructure; Gene expression; Growth factors; Histamine; Humans; Hypertension; Hypertension, Pulmonary - blood; Hypertension, Pulmonary - metabolism; Hypertension, Pulmonary - pathology; Hypertension, Pulmonary - physiopathology; Kinases; Lentivirus - metabolism; Lung - metabolism; Lungs; Male; Metastasis; Microparticles; Monocrotaline; Mutation; Mutation - genetics; Myocytes, Smooth Muscle - metabolism; Original Research; Phenotypes; Protein Transport; Proteins; Pulmonary arteries; Pulmonary artery; Pulmonary Artery - metabolism; Pulmonary Artery - pathology; Pulmonary Artery - physiopathology; Pulmonary hypertension; Rats, Sprague-Dawley; Smooth muscle; Tumor Protein, Translationally-Controlled 1; Ultracentrifugation; Vascular Remodeling; Veins & arteries; Vesicles; endothelium; pulmonary; remodeling; hypertension; exosomes