Novel Transcatheter Mitral Valve Prosthesis for Patients With Severe Mitral Annular Calcification
Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak. The objective of this study was to evaluate the potential for transcatheter mitral va...
Saved in:
| Published in | Journal of the American College of Cardiology Vol. 74; no. 11; pp. 1431 - 1440 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
17.09.2019
Elsevier Limited |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0735-1097 1558-3597 1558-3597 |
| DOI | 10.1016/j.jacc.2019.07.069 |
Cover
| Abstract | Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak.
The objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis.
Nine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy.
Device implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up.
Transcatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted.
[Display omitted] |
|---|---|
| AbstractList | Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak.BACKGROUNDTreatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak.The objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis.OBJECTIVESThe objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis.Nine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy.METHODSNine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy.Device implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up.RESULTSDevice implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up.Transcatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted.CONCLUSIONSTranscatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted. Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak. The objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis. Nine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy. Device implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up. Transcatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted. [Display omitted] AbstractBackgroundTreatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak. ObjectivesThe objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis. MethodsNine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy. ResultsDevice implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up. ConclusionsTranscatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted. Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak. The objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis. Nine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy. Device implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up. Transcatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted. BackgroundTreatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrioventricular groove disruption and significant paravalvular leak.ObjectivesThe objective of this study was to evaluate the potential for transcatheter mitral valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis.MethodsNine patients (77 ± 6 years of age; 5 men) were treated with the valve, using transapical delivery performed under general anesthesia and with guidance from transesophageal echocardiography and fluoroscopy.ResultsDevice implantation was successful with relief of MR in all 9 patients. There were no procedural deaths. In 1 patient, left ventricular outflow tract obstruction occurred due to malrotation of the prosthesis, and successful alcohol septal ablation was performed. During a median follow-up of 12 months (range 1 to 28 months), there was 1 cardiac death, 1 noncardiac death, no other mortality, and no prosthetic dysfunction, and MR remained absent in all treated patients. Rehospitalization for heart failure occurred in 2 patients who did not die subsequently. Clinical improvement with mild or no symptoms occurred in all patients alive at the end of follow-up.ConclusionsTranscatheter mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is feasible and can result in MR relief with symptom improvement. Further evaluation of this approach for these high-risk patients is warranted. |
| Author | Tchetche, Didier Rizik, David Sorajja, Paul Gössl, Mario Sun, Benjamin Babaliaros, Vasilis Berthoumieu, Pierre Lisko, John C. Guyton, Robert Blanke, Philipp Cavalcante, João L. Schäfer, Ulrich Burke, Robert F. Dumonteil, Nicolas Bae, Richard Conradi, Lenard Riley, Robert D. |
| Author_xml | – sequence: 1 givenname: Paul surname: Sorajja fullname: Sorajja, Paul email: paul.sorajja@allina.com organization: Valve Science Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota – sequence: 2 givenname: Mario surname: Gössl fullname: Gössl, Mario organization: Valve Science Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota – sequence: 3 givenname: Vasilis surname: Babaliaros fullname: Babaliaros, Vasilis organization: Emory Structural Heart and Valve Center, Atlanta, Georgia – sequence: 4 givenname: David surname: Rizik fullname: Rizik, David organization: HonorHealth, Phoenix, Arizona – sequence: 5 givenname: Lenard surname: Conradi fullname: Conradi, Lenard organization: University Heart Center, Hamburg, Germany – sequence: 6 givenname: Richard surname: Bae fullname: Bae, Richard organization: Valve Science Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota – sequence: 7 givenname: Robert F. surname: Burke fullname: Burke, Robert F. organization: HonorHealth, Phoenix, Arizona – sequence: 8 givenname: Ulrich surname: Schäfer fullname: Schäfer, Ulrich organization: University Heart Center, Hamburg, Germany – sequence: 9 givenname: John C. surname: Lisko fullname: Lisko, John C. organization: Emory Structural Heart and Valve Center, Atlanta, Georgia – sequence: 10 givenname: Robert D. surname: Riley fullname: Riley, Robert D. organization: HonorHealth, Phoenix, Arizona – sequence: 11 givenname: Robert surname: Guyton fullname: Guyton, Robert organization: Emory Structural Heart and Valve Center, Atlanta, Georgia – sequence: 12 givenname: Nicolas surname: Dumonteil fullname: Dumonteil, Nicolas organization: Clinique Pasteur, Toulouse, France – sequence: 13 givenname: Pierre surname: Berthoumieu fullname: Berthoumieu, Pierre organization: Clinique Pasteur, Toulouse, France – sequence: 14 givenname: Didier surname: Tchetche fullname: Tchetche, Didier organization: Clinique Pasteur, Toulouse, France – sequence: 15 givenname: Philipp surname: Blanke fullname: Blanke, Philipp organization: Department of Radiology, St. Paul’s Hospital and University of British Columbia, Vancouver, British Columbia, Canada – sequence: 16 givenname: João L. surname: Cavalcante fullname: Cavalcante, João L. organization: Valve Science Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota – sequence: 17 givenname: Benjamin surname: Sun fullname: Sun, Benjamin organization: Valve Science Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31514943$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkt9r1TAUx4NM3N30H_BBCr740npO0zapiDAu_oKpg019DFl6wlJz25m0F_bfm3q3PVxwPgXC53MSvt9zxA6GcSDGniMUCNi87oteG1OUgG0BooCmfcRWWNcy53UrDtgKBK9zhFYcsqMYewBoJLZP2CHHGqu24iumv45b8tlF0EM0erqiiUL2xU1B--yH9lvKzsIY0310MbNjyM705GiYYvbTTVfZOW0p0J1wMgyz1yFba2-cdWmeG4en7LHVPtKz2_OYff_w_mL9KT_99vHz-uQ0N1ULU46yFGgB0FRVZekSoUTgvCaLtpYchLVQd0IYg5wSBZpbY6Uh2XXSdiU_Zq92c6_D-HumOKmNi4a81wONc1Rl2UILILFJ6Ms9tB_nMKTfJUqKCiRIkagXt9R8uaFOXQe30eFG3YWXgHIHmBRRDGTvEQS1NKR6tTSkloYUCJUaSpLck4yb_gaVInT-YfXtTqUU49ZRUNGkLgx1LpCZVDe6h_V3e7rxbkgt-V90Q_E-AlSxVKDOl-1Zlgdb3qBsZBrw5t8D_vf6H-GM05g |
| CitedBy_id | crossref_primary_10_1016_j_ccl_2021_01_006 crossref_primary_10_1016_j_jcin_2023_06_044 crossref_primary_10_1016_j_jacc_2021_04_051 crossref_primary_10_1016_j_jcin_2024_08_010 crossref_primary_10_1016_j_jscai_2023_101195 crossref_primary_10_4244_EIJ_D_21_00205 crossref_primary_10_1053_j_semtcvs_2025_01_008 crossref_primary_10_1016_j_arcmed_2022_12_009 crossref_primary_10_4081_monaldi_2022_2404 crossref_primary_10_1007_s00392_020_01757_z crossref_primary_10_4244_EIJ_D_22_00890 crossref_primary_10_1016_j_jcin_2022_11_022 crossref_primary_10_1016_j_xjse_2024_100011 crossref_primary_10_1016_j_cjca_2020_11_018 crossref_primary_10_1007_s11886_021_01524_0 crossref_primary_10_1016_j_jcin_2020_12_038 crossref_primary_10_3390_medicina60071082 crossref_primary_10_1016_j_echo_2021_04_007 crossref_primary_10_3389_fcvm_2021_782278 crossref_primary_10_1016_j_jcin_2021_10_011 crossref_primary_10_3389_fcvm_2022_967473 crossref_primary_10_1016_j_jcin_2024_07_038 crossref_primary_10_1055_a_1245_9796 crossref_primary_10_3389_fcvm_2020_531843 crossref_primary_10_1016_j_jacc_2020_01_002 crossref_primary_10_1016_j_jjcc_2020_10_020 crossref_primary_10_3389_fcvm_2020_592909 crossref_primary_10_1016_j_xjse_2025_100045 crossref_primary_10_1002_ejhf_2434 crossref_primary_10_1016_j_xjtc_2020_06_023 crossref_primary_10_17925_HI_2023_17_1_19 crossref_primary_10_1038_s41569_020_0395_7 crossref_primary_10_1016_j_jaccas_2021_04_018 crossref_primary_10_4244_EIJ_D_21_00745 crossref_primary_10_1002_ccd_31405 crossref_primary_10_1016_j_jscai_2025_102582 crossref_primary_10_1053_j_jvca_2022_05_019 crossref_primary_10_3390_jcdd11050153 crossref_primary_10_1093_eurheartj_ehab395 crossref_primary_10_4244_EIJV15I10A157 crossref_primary_10_1007_s11886_021_01556_6 crossref_primary_10_1016_j_shj_2024_100294 crossref_primary_10_1016_j_jacc_2022_06_009 crossref_primary_10_1093_ejcts_ezab389 crossref_primary_10_1007_s11886_021_01567_3 crossref_primary_10_1016_j_xjtc_2021_08_007 crossref_primary_10_15420_cfr_2022_10 crossref_primary_10_4244_EIJ_D_19_01051 crossref_primary_10_1016_j_shj_2022_100012 crossref_primary_10_1016_j_jacc_2019_06_071 crossref_primary_10_1016_j_athoracsur_2020_04_148 crossref_primary_10_1016_j_jtcvs_2020_01_088 crossref_primary_10_1002_ccd_30988 crossref_primary_10_15836_ccar2023_249 crossref_primary_10_1016_j_jcin_2023_12_027 crossref_primary_10_1053_j_jvca_2020_10_031 crossref_primary_10_47803_rjc_2021_31_3_555 crossref_primary_10_3389_fcvm_2024_1431639 crossref_primary_10_1016_j_jcmg_2021_01_022 crossref_primary_10_1016_j_recesp_2021_11_023 crossref_primary_10_4244_EIJ_E_21_00009 crossref_primary_10_1016_j_jtcvs_2021_08_047 crossref_primary_10_1016_S0140_6736_23_02755_1 crossref_primary_10_1148_rg_2020200027 crossref_primary_10_1002_ejhf_2492 crossref_primary_10_3390_life13071511 crossref_primary_10_3390_jcm11123377 crossref_primary_10_1016_j_jcct_2020_10_003 crossref_primary_10_1016_j_ijcard_2024_132741 crossref_primary_10_2459_JCM_0000000000001384 crossref_primary_10_3389_fcvm_2023_1130212 crossref_primary_10_3390_jcm10245973 crossref_primary_10_1007_s00398_022_00490_1 crossref_primary_10_3389_fcvm_2020_00061 |
| Cites_doi | 10.1016/j.jacc.2016.10.068 10.1016/S0022-5223(96)70332-X 10.1016/j.jacc.2018.07.032 10.1016/j.jcin.2016.04.022 10.1016/j.jcmg.2016.01.005 10.1016/j.atherosclerosis.2010.08.072 10.1007/s11748-013-0207-7 10.1016/j.jcmg.2014.07.028 10.1016/j.jacc.2015.05.049 10.1016/j.jcin.2017.01.035 10.1016/j.jcin.2017.03.026 10.21037/acs.2018.10.07 10.1016/j.jacc.2018.07.033 10.1016/j.jacc.2018.02.054 10.1016/j.athoracsur.2018.07.098 |
| ContentType | Journal Article |
| Copyright | 2019 American College of Cardiology Foundation American College of Cardiology Foundation Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. 2019. American College of Cardiology Foundation |
| Copyright_xml | – notice: 2019 American College of Cardiology Foundation – notice: American College of Cardiology Foundation – notice: Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. – notice: 2019. American College of Cardiology Foundation |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7T5 7TK H94 K9. NAPCQ 7X8 |
| DOI | 10.1016/j.jacc.2019.07.069 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Immunology Abstracts Neurosciences Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium Immunology Abstracts Neurosciences Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE AIDS and Cancer Research Abstracts |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1558-3597 |
| EndPage | 1440 |
| ExternalDocumentID | 31514943 10_1016_j_jacc_2019_07_069 S0735109719361868 1_s2_0_S0735109719361868 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | California France United States--US Germany |
| GeographicLocations_xml | – name: Germany – name: California – name: France – name: United States--US |
| GroupedDBID | --- --K --M .1- .FO .~1 0R~ 18M 1B1 1P~ 1~. 1~5 2WC 4.4 457 4G. 53G 5GY 5RE 5VS 6PF 7-5 71M 8P~ AABNK AABVL AAEDT AAEDW AAIKJ AALRI AAOAW AAQFI AAQQT AAXUO ABBQC ABFNM ABFRF ABLJU ABMAC ABMZM ABOCM ACGFO ACGFS ACIUM ACJTP ACPRK ACVFH ADBBV ADCNI ADEZE ADVLN AEFWE AEKER AENEX AEUPX AEVXI AEXQZ AFPUW AFRAH AFRHN AFTJW AGCQF AGYEJ AHMBA AIGII AITUG AJRQY AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ BAWUL BLXMC CS3 DIK DU5 E3Z EBS EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FNPLU G-Q GBLVA GX1 HVGLF IHE IXB J1W K-O KQ8 L7B MO0 N9A O-L O9- OA. OAUVE OK1 OL~ OZT P-8 P-9 P2P PC. PQQKQ Q38 ROL RPZ SCC SDF SDG SDP SES SSZ TR2 UNMZH UV1 W8F WH7 WOQ WOW YYM YZZ Z5R .55 .GJ 0SF 1CY 29L 3O- 3V. 6I. 7RV AACTN AAFTH AAKUH AAQXK AAYOK ABVKL ABWVN ABXDB ACRPL ADMUD ADNMO AFCTW AFETI AFFNX AGHFR AJOXV AMFUW ASPBG AVWKF AZFZN BENPR BPHCQ FGOYB H13 HX~ HZ~ J5H N4W NCXOZ PROAC QTD R2- RIG SEW T5K X7M XPP YYP ZGI ZXP AAIAV ABJNI EFLBG LCYCR NAHTW ZA5 AAYWO AAYXX AGQPQ CITATION CGR CUY CVF ECM EIF NPM 7T5 7TK H94 K9. NAPCQ 7X8 ~HD |
| ID | FETCH-LOGICAL-c490t-18271f001c444feb10210335ef1f58307ff05d77cc13e01c0a3fcf8ce8dd8fd23 |
| IEDL.DBID | IXB |
| ISSN | 0735-1097 1558-3597 |
| IngestDate | Sun Sep 28 02:44:04 EDT 2025 Fri Jul 25 09:24:21 EDT 2025 Thu Apr 03 06:59:42 EDT 2025 Tue Jul 01 01:24:22 EDT 2025 Thu Apr 24 23:00:52 EDT 2025 Fri Feb 23 02:34:16 EST 2024 Sun Feb 23 10:19:40 EST 2025 Tue Aug 26 19:31:40 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 11 |
| Keywords | mitral annular calcification NYHA TMVR MR EOA transcatheter LVOT mitral valve replacement MAC mitral regurgitation left ventricular outflow tract effective orifice area New York Heart Association transcatheter mitral valve replacement |
| Language | English |
| License | This article is made available under the Elsevier license. Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c490t-18271f001c444feb10210335ef1f58307ff05d77cc13e01c0a3fcf8ce8dd8fd23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.clinicalkey.com/#!/content/1-s2.0-S0735109719361868 |
| PMID | 31514943 |
| PQID | 2287408087 |
| PQPubID | 2031078 |
| PageCount | 10 |
| ParticipantIDs | proquest_miscellaneous_2290900816 proquest_journals_2287408087 pubmed_primary_31514943 crossref_primary_10_1016_j_jacc_2019_07_069 crossref_citationtrail_10_1016_j_jacc_2019_07_069 elsevier_sciencedirect_doi_10_1016_j_jacc_2019_07_069 elsevier_clinicalkeyesjournals_1_s2_0_S0735109719361868 elsevier_clinicalkey_doi_10_1016_j_jacc_2019_07_069 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2019-09-17 |
| PublicationDateYYYYMMDD | 2019-09-17 |
| PublicationDate_xml | – month: 09 year: 2019 text: 2019-09-17 day: 17 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: New York |
| PublicationTitle | Journal of the American College of Cardiology |
| PublicationTitleAlternate | J Am Coll Cardiol |
| PublicationYear | 2019 |
| Publisher | Elsevier Inc Elsevier Limited |
| Publisher_xml | – name: Elsevier Inc – name: Elsevier Limited |
| References | Stone, Adams, Abraham (bib11) 2015 Saran, Greason, Schaff (bib13) 2019; 107 Muller, Farivar, Jansz (bib7) 2017; 69 Kanjanauthai, Nasir, Katz (bib15) 2010; 213 Gillinov, Desai, Mick (bib14) 2018; 72 Blanke, Dvir, Cheung (bib8) 2015; 8 bib10 Russell, Guerrero, Salinger (bib6) 2018; 72 Nissen, Lamelas, George, Umana-Pizano, Nguyen (bib5) 2018; 7 Guerrero, Dvir, Himbert (bib3) 2016; 9 Guerrero, Urena, Himbert (bib4) 2018; 71 Blanke, Naoum, Dvir (bib16) 2017; 10 Okada (bib1) 2013; 61 Carpentier, Pelletin, Fuzellier (bib2) 1996; 111 Sorajja, Gossl, Bae (bib9) 2017; 10 Babaliaros, Greenbaum, Khan (bib12) 2017; 10 Carpentier (10.1016/j.jacc.2019.07.069_bib2) 1996; 111 Saran (10.1016/j.jacc.2019.07.069_bib13) 2019; 107 Nissen (10.1016/j.jacc.2019.07.069_bib5) 2018; 7 Kanjanauthai (10.1016/j.jacc.2019.07.069_bib15) 2010; 213 Stone (10.1016/j.jacc.2019.07.069_bib11) 2015 Okada (10.1016/j.jacc.2019.07.069_bib1) 2013; 61 Blanke (10.1016/j.jacc.2019.07.069_bib8) 2015; 8 Blanke (10.1016/j.jacc.2019.07.069_bib16) 2017; 10 Russell (10.1016/j.jacc.2019.07.069_bib6) 2018; 72 Muller (10.1016/j.jacc.2019.07.069_bib7) 2017; 69 Guerrero (10.1016/j.jacc.2019.07.069_bib4) 2018; 71 Guerrero (10.1016/j.jacc.2019.07.069_bib3) 2016; 9 Gillinov (10.1016/j.jacc.2019.07.069_bib14) 2018; 72 Babaliaros (10.1016/j.jacc.2019.07.069_bib12) 2017; 10 Sorajja (10.1016/j.jacc.2019.07.069_bib9) 2017; 10 31514944 - J Am Coll Cardiol. 2019 Sep 17;74(11):1441-1443 |
| References_xml | – volume: 9 start-page: 1361 year: 2016 end-page: 1371 ident: bib3 article-title: Transcatheter mitral replacement in native mitral valve disease with severe mitral annular calcification. Results from the first multicenter global registry publication-title: J Am Coll Cardiol Intv – volume: 111 start-page: 718 year: 1996 end-page: 729 ident: bib2 article-title: Extensive calcification of the mitral valve annulus: pathology and surgical management publication-title: J Thorac Cardiovasc Surg – volume: 10 start-page: 1178 year: 2017 end-page: 1179 ident: bib9 article-title: Severe mitral annular calcification. First experience with transcatheter therapy using a dedicated mitral prosthesis publication-title: J Am Coll Cardiol Intv – ident: bib10 article-title: Online STS Adult Cardiac Surgery Risk Calculator – volume: 107 start-page: 444 year: 2019 end-page: 452 ident: bib13 article-title: Does mitral valve calcium in patients undergoing mitral valve replacement portend worse survival? publication-title: Ann Thorac Surg – volume: 61 start-page: 619 year: 2013 end-page: 625 ident: bib1 article-title: Surgical management of mitral annular calcification publication-title: Gen Thorac Cardiovasc Surg – volume: 72 start-page: 1437 year: 2018 end-page: 1448 ident: bib6 article-title: Open atrial transcatheter mitral valve replacement in patients with mitral annular calcification publication-title: J Am Coll Cardiol – volume: 69 start-page: 381 year: 2017 end-page: 391 ident: bib7 article-title: Transcatheter mitral valve replacement for patients with symptomatic mitral regurgitation: a global feasibility trial publication-title: J Am Coll Cardiol – volume: 7 start-page: 827 year: 2018 end-page: 829 ident: bib5 article-title: Minimally invasive transatrial mitral valve replacement in mitral annular calcification publication-title: Ann Cardiothorac Surg – volume: 10 start-page: 798 year: 2017 end-page: 809 ident: bib12 article-title: Intentional percutaneous laceration of the anterior mitral leaflet to prevent outflow obstruction during transcatheter mitral valve replacement: first-in-human experience publication-title: J Am Coll Cardiol Intv – volume: 10 start-page: 482 year: 2017 end-page: 485 ident: bib16 article-title: Predicting LVOT obstruction in transcatheter mitral valve implantation. Concept of the neo-LVOT publication-title: J Am Coll Cardiol Img – volume: 71 start-page: 1841 year: 2018 end-page: 1853 ident: bib4 article-title: One-year outcomes of transcatheter mitral valve replacement in patients with severe mitral annular calcification publication-title: J Am Coll Cardiol – volume: 72 start-page: 1449 year: 2018 end-page: 1451 ident: bib14 article-title: Mitral annular calcification: the search for safer options publication-title: J Am Coll Cardiol – volume: 8 start-page: 612 year: 2015 end-page: 615 ident: bib8 article-title: Mitral annular evaluation with CT in the context of transcatheter mitral valve replacement publication-title: J Am Coll Cardiol Img – volume: 213 start-page: 558 year: 2010 end-page: 562 ident: bib15 article-title: Relationships of mitral annular calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Atherosclerosis – start-page: 308 year: 2015 end-page: 321 ident: bib11 article-title: Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement. Part 2: endpoint definitions: a consensus document from the Mitral Valve Academic Research Consortium publication-title: J Am Coll Cardiol – volume: 69 start-page: 381 year: 2017 ident: 10.1016/j.jacc.2019.07.069_bib7 article-title: Transcatheter mitral valve replacement for patients with symptomatic mitral regurgitation: a global feasibility trial publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2016.10.068 – volume: 111 start-page: 718 year: 1996 ident: 10.1016/j.jacc.2019.07.069_bib2 article-title: Extensive calcification of the mitral valve annulus: pathology and surgical management publication-title: J Thorac Cardiovasc Surg doi: 10.1016/S0022-5223(96)70332-X – volume: 72 start-page: 1449 year: 2018 ident: 10.1016/j.jacc.2019.07.069_bib14 article-title: Mitral annular calcification: the search for safer options publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.07.032 – volume: 9 start-page: 1361 year: 2016 ident: 10.1016/j.jacc.2019.07.069_bib3 article-title: Transcatheter mitral replacement in native mitral valve disease with severe mitral annular calcification. Results from the first multicenter global registry publication-title: J Am Coll Cardiol Intv doi: 10.1016/j.jcin.2016.04.022 – volume: 10 start-page: 482 year: 2017 ident: 10.1016/j.jacc.2019.07.069_bib16 article-title: Predicting LVOT obstruction in transcatheter mitral valve implantation. Concept of the neo-LVOT publication-title: J Am Coll Cardiol Img doi: 10.1016/j.jcmg.2016.01.005 – volume: 213 start-page: 558 year: 2010 ident: 10.1016/j.jacc.2019.07.069_bib15 article-title: Relationships of mitral annular calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2010.08.072 – volume: 61 start-page: 619 year: 2013 ident: 10.1016/j.jacc.2019.07.069_bib1 article-title: Surgical management of mitral annular calcification publication-title: Gen Thorac Cardiovasc Surg doi: 10.1007/s11748-013-0207-7 – volume: 8 start-page: 612 year: 2015 ident: 10.1016/j.jacc.2019.07.069_bib8 article-title: Mitral annular evaluation with CT in the context of transcatheter mitral valve replacement publication-title: J Am Coll Cardiol Img doi: 10.1016/j.jcmg.2014.07.028 – start-page: 308 year: 2015 ident: 10.1016/j.jacc.2019.07.069_bib11 article-title: Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement. Part 2: endpoint definitions: a consensus document from the Mitral Valve Academic Research Consortium publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2015.05.049 – volume: 10 start-page: 798 year: 2017 ident: 10.1016/j.jacc.2019.07.069_bib12 article-title: Intentional percutaneous laceration of the anterior mitral leaflet to prevent outflow obstruction during transcatheter mitral valve replacement: first-in-human experience publication-title: J Am Coll Cardiol Intv doi: 10.1016/j.jcin.2017.01.035 – volume: 10 start-page: 1178 year: 2017 ident: 10.1016/j.jacc.2019.07.069_bib9 article-title: Severe mitral annular calcification. First experience with transcatheter therapy using a dedicated mitral prosthesis publication-title: J Am Coll Cardiol Intv doi: 10.1016/j.jcin.2017.03.026 – volume: 7 start-page: 827 year: 2018 ident: 10.1016/j.jacc.2019.07.069_bib5 article-title: Minimally invasive transatrial mitral valve replacement in mitral annular calcification publication-title: Ann Cardiothorac Surg doi: 10.21037/acs.2018.10.07 – volume: 72 start-page: 1437 year: 2018 ident: 10.1016/j.jacc.2019.07.069_bib6 article-title: Open atrial transcatheter mitral valve replacement in patients with mitral annular calcification publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.07.033 – volume: 71 start-page: 1841 year: 2018 ident: 10.1016/j.jacc.2019.07.069_bib4 article-title: One-year outcomes of transcatheter mitral valve replacement in patients with severe mitral annular calcification publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.02.054 – volume: 107 start-page: 444 year: 2019 ident: 10.1016/j.jacc.2019.07.069_bib13 article-title: Does mitral valve calcium in patients undergoing mitral valve replacement portend worse survival? publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2018.07.098 – reference: 31514944 - J Am Coll Cardiol. 2019 Sep 17;74(11):1441-1443 |
| SSID | ssj0006819 |
| Score | 2.5637798 |
| Snippet | Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal... AbstractBackgroundTreatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for... BackgroundTreatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal... Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1431 |
| SubjectTerms | Aged Aged, 80 and over Anesthesia Anticoagulants Calcification Calcinosis - surgery Cardiac arrhythmia Cardiac Catheterization Cardiology Cardiovascular Catheters Congestive heart failure Echocardiography Endocarditis Feasibility studies Female Fluoroscopy Heart attacks Heart failure Heart Valve Diseases - surgery Heart Valve Prosthesis Implantation - methods Hospitalization Hospitals Humans Hypertension Male Medical equipment mitral annular calcification Mitral valve Mitral Valve - surgery mitral valve replacement Mortality Ostomy Patients Prostheses Regurgitation Risk groups Severity of Illness Index Stroke Surgery Thoracic surgery transcatheter Ventricle |
| Title | Novel Transcatheter Mitral Valve Prosthesis for Patients With Severe Mitral Annular Calcification |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0735109719361868 https://www.clinicalkey.es/playcontent/1-s2.0-S0735109719361868 https://dx.doi.org/10.1016/j.jacc.2019.07.069 https://www.ncbi.nlm.nih.gov/pubmed/31514943 https://www.proquest.com/docview/2287408087 https://www.proquest.com/docview/2290900816 |
| Volume | 74 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9wwDI8YD2gvE-zzxocyibepu7RJm_YRTiCEdAiJsd1bFFJHFJ3u0HrwyN-OnaaV0BiTeGxrK5Ht2L80tsPYfo2wFlSdJ1BLnSib6aQqoEqkraVwWeUKSQXO07Pi5FKdzvLZGpv0tTCUVhl9f-fTg7eOb8ZRmuPbphlfoHHmdH6KECQ0fUc_TFWlVMQ3Oxy8cVGGyz2IOCHqWDjT5XjdWEdtDNMqNPCkpOfng9O_wGcIQseb7F1Ej_ygm-AWW4PFe7YxjefjH5g9W97DnIcAFBqyotT4tKG_GfyXnd8DP6cqj2tom5YjXOXnXVvVlv9uVtf8AtCwoWeg1vu47-UTOw-Je0GHH9nl8dHPyUkSL1FInKrEKsH9g049BiOnlPLomWmTJ2UOPvV5iSvce5HXWjuXSkAqYaV3vnRQ1nXpUZWf2PpiuYAvjKurwmdWe5dlXinrMNILmSGgETmgbvWIpb30jIsdxumii7npU8luDEnckMSN0AYlPmLfB57brr_Gi9SyV4rpK0fR1xl0_y9y6ee4oI3LtTWpaTMjzF8mNWL5wPnEKv874k5vMWYYJKOrBRCglyiob8NnXM10RGMXsLwjmkpUBNOKEfvcWdogFongTFVKfn3lpLbZW3qiZJdU77D11Z872EVEtbraY29-PKR7YeE8AvI-HYA |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VIgEXVF5loQUjcUNhndiJk2O1olqgu6rUFnqzXMdWU612K7Ltkd_OjOMEIdoicY1nZGs8nvkczwPgfY2w1sk6T1wtVCJNppKqcFUiTC24zSpbCEpwns2L6Yn8cpqfbsCkz4WhsMpo-zubHqx1_DKO0hxfNs34CJUzp_dThCCh6Ps9uC-pzQEq9cefv-M8ijJ09yDqhMhj5kwX5HVhLNUxTKtQwZOinm_2Trehz-CF9rfgcYSPbK9b4RPYcMun8GAWH8ifgZmvrt2CBQ8UKrKi2Nisod8Z7JtZXDt2SGke565tWoZ4lR12dVVb9r1Zn7Mjh5rtegaqvY8XXzYxixC5FzbxOZzsfzqeTJPYRSGxsuLrBC8QKvXojayU0qNpplueELnzqc9LPOLe87xWytpUOKTiRnjrS-vKui497uUL2Fyulu4lMHlW-Mwob7PMS2ksunouMkQ0PHe4uWoEaS89bWOJcep0sdB9LNmFJolrkrjmSqPER_Bh4LnsCmzcSS36TdF96igaO432_04udROXa-N5bXWq20xz_ZdOjSAfOP9Qy3_OuNNrjB4myai3ACL0EgX1bhjG40xvNGbpVldEU_GKcFoxgu1O0waxCERnspLi1X8u6i08nB7PDvTB5_nX1_CIRijyJVU7sLn-ceV2EV6tz96E4_MLZTwfjw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Novel+Transcatheter+Mitral+Valve+Prosthesis+for+Patients+With+Severe+Mitral+Annular+Calcification&rft.jtitle=Journal+of+the+American+College+of+Cardiology&rft.au=Sorajja%2C+Paul&rft.au=G%C3%B6ssl%2C+Mario&rft.au=Babaliaros%2C+Vasilis&rft.au=Rizik%2C+David&rft.date=2019-09-17&rft.pub=Elsevier+Limited&rft.issn=0735-1097&rft.eissn=1558-3597&rft.volume=74&rft.issue=11&rft.spage=1431&rft_id=info:doi/10.1016%2Fj.jacc.2019.07.069&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F07351097%2FS0735109718X00424%2Fcov150h.gif |