Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion - Glover, Elisa I.; Phillips, Stuart M.; Oates, Bryan R.; Tang, Jason E.; Tarnopolsky, Mark A.; Selby, Anna; Smith, Kenneth; Rennie, Michael J. (The Journal of physiology, 2008)
Keywords: Adult; Amino Acids - administration & dosage; Amino Acids - metabolism; Amino Acids - pharmacology; Amino Acids, Essential - blood; Amino Acids, Essential - metabolism; Dose-Response Relationship, Drug; Elongation Factor 2 Kinase - metabolism; Female; Focal Adhesion Protein-Tyrosine Kinases - metabolism; Glycogen Synthase Kinase 3 - metabolism; Glycogen Synthase Kinase 3 beta; Humans; Immobilization - methods; Infusions, Intravenous; Insulin - blood; Male; Muscle Proteins - biosynthesis; Muscle Strength - drug effects; Muscle Strength - physiology; Myofibrils - drug effects; Myofibrils - metabolism; Myofibrils - physiology; Phosphorylation - drug effects; Protein Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Quadriceps Muscle - drug effects; Quadriceps Muscle - metabolism; Quadriceps Muscle - physiology; Ribosomal Protein S6 Kinases, 70-kDa - metabolism; Skeletal Muscle and Exercise; TOR Serine-Threonine Kinases; Ubiquitination - drug effects; Young Adult