Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients

To investigate if increased dietary fiber, in terms of kiwifruit, is effective in Chinese constipated patients. 33 constipated patients and 20 healthy volunteers were recruited for a 4-wk treatment of kiwi fruit twice daily. Response during wk 1-4 was defined as an increase in complete spontaneous b...

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Published inWorld journal of gastroenterology : WJG Vol. 13; no. 35; pp. 4771 - 4775
Main Author Chan, Annie On On
Format Journal Article
LanguageEnglish
Published United States Department of Medicine, The University of Hong Kong, Hong Kong, China 21.09.2007
Baishideng Publishing Group Co., Limited
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ISSN1007-9327
2219-2840
DOI10.3748/wjg.v13.i35.4771

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Summary:To investigate if increased dietary fiber, in terms of kiwifruit, is effective in Chinese constipated patients. 33 constipated patients and 20 healthy volunteers were recruited for a 4-wk treatment of kiwi fruit twice daily. Response during wk 1-4 was defined as an increase in complete spontaneous bowl, motion (CSBM) > or = 1/wk. Secondary efficacy included response during wk 1-4, individual symptoms and scores of bowel habits and constipation. Responses were compared with the baseline run-in period. Colonic transit time and anorectal manometry were performed before and after treatment. Responder rate was 54.5% in the constipated group. The mean CSBM increased after treatment (2.2 +/- 2.6 vs 4.4 +/- 4.6, P = 0.013). There was also improvement in the scores for bothersomeness of constipation (P = 0.02), and satisfaction of bowel habit (P = 0.001), and decreased in days of laxative used (P = 0.003). There was also improvement in transit time (P = 0.003) and rectal sensation (P < 0.05). However, there was no change in the bowel symptoms or anorectal physiology in the healthy subjects. Increasing dietary fiber intake is effective in relieving chronic constipation in Chinese population.
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Correspondence to: Annie On On Chan, MD, PhD, Associate Professor, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China. aoochan@hku.hk
Telephone: +852-28553890 Fax: +852-28725828
Author contributions: All authors contributed equally to the work.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v13.i35.4771