Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes - Hui, Daniel J; Basner-Tschakarjan, Etiena; Chen, Yifeng; Davidson, Robert J; Buchlis, George; Yazicioglu, Mustafa; Pien, Gary C; Finn, Jonathan D; Haurigot, Virginia; Tai, Alex; Scott, David W; Cousens, Leslie P; et al. (Molecular therapy, 2013)
Keywords: Animals; Antigens; Antigens, Viral - genetics; Antigens, Viral - immunology; Capsid - immunology; Capsid Proteins - genetics; Capsid Proteins - immunology; Capsid Proteins - metabolism; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - metabolism; Cell cycle; Cells, Cultured; Clinical trials; Dependovirus - genetics; Dependovirus - immunology; Enzymes; Epitopes, T-Lymphocyte - genetics; Epitopes, T-Lymphocyte - immunology; Epitopes, T-Lymphocyte - metabolism; Genetic Therapy; Genetic Vectors; Genomes; Hemophilia; Histocompatibility Antigens Class I - immunology; Histocompatibility Antigens Class II - immunology; Humans; Immunoglobulin G - genetics; Immunoglobulin G - immunology; Life Sciences; Liver; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Original; Peptides; Spleen - immunology; T-Lymphocytes, Regulatory - immunology; Viruses; United States--US; Pennsylvania