The development of non-coding RNA ontology

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. W...

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Published inInternational journal of data mining and bioinformatics Vol. 15; no. 3; p. 214
Main Authors Huang, Jingshan, Eilbeck, Karen, Smith, Barry, Blake, Judith A, Dou, Dejing, Huang, Weili, Natale, Darren A, Ruttenberg, Alan, Huan, Jun, Zimmermann, Michael T, Jiang, Guoqian, Lin, Yu, Wu, Bin, Strachan, Harrison J, de Silva, Nisansa, Kasukurthi, Mohan Vamsi, Jha, Vikash Kumar, He, Yongqun, Zhang, Shaojie, Wang, Xiaowei, Liu, Zixing, Borchert, Glen M, Tan, Ming
Format Journal Article
LanguageEnglish
Published Switzerland 2016
Subjects
bio-ontologies
ontology development
reference ontology
non-coding RNA
semantic data annotation
domain ontology
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ISSN1748-5673
1748-5681
DOI10.1504/IJDMB.2016.077072

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Summary:Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.
ISSN:1748-5673
1748-5681
DOI:10.1504/IJDMB.2016.077072